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The map label for this gene is fumA [C]

Identifier: 94314391

GI number: 94314391

Start: 2216859

End: 2217701

Strand: Reverse

Name: fumA [C]

Synonym: Rmet_5472

Alternate gene names: 94314391

Gene position: 2217701-2216859 (Counterclockwise)

Preceding gene: 94314392

Following gene: 94314390

Centisome position: 85.95

GC content: 57.53

Gene sequence:

>843_bases
ATGAGAGAGATTCACGTAGACACCCTGACCGATGCCGTCGCCAAGCTGTGCATCGATGCTTGCCACCGCTTGCCCGACAA
TCTGGTGGAAAGCTTTCACAAGGCTGCCGAGAAGGAAGTATCCCCGCTTGGCAAGTCGGTGCTCATGAAGCTGATTGACA
ACGACCGCATCGCTCGCGAAAACGATGTCTCGTATTGCCACGACACTGGACTGGCGATTGTCTTCGTGGAAGTTGGCCAG
GATGTGCATATCGTCGGCGGGAGCTACGAAGATGCCATTCAGGCGGGTGTACGCAAGGGCTACGCCGAAGGCTACATGCG
CAAATCGGTCGTCTCGGACCCGTTGCTTCGCGTGAACAGCAATGACAACACGCCGGCGGTCGTCCATACGGAAATTGTCC
CCGGAGACAATATTGAAGTCACCGTGGTCCCCAAGGGTGGTGGAAGCGAGAACTGGAGCACGATGAAGTTCCTGCTTCCG
GGCGAAGGTGCTGAAGGCGTAAAGAAGTTCGTGCTGTCGGCTATTGAAGCTGCGGGCGGTGCTGCGTGCCCACCCCTGAC
AGTAGGTGTGGGCATTGGCGGCAGTTTCGACAAGGTCACGGCCATCGCAAAGAAGGCGATCCTGCGGGATATTGGTGTTC
ATCACAAGGAACCGCACGTTGCCAAGCTGGAAGCCGAGCTTCTTGATGCCATCAACAAGACCGGTATCGGCCCGCAAGGT
TATGGCGGTGTCAACACGGCGCTTTGGGTCTCGGTAGAGACCTATGCTTGTCACATCACCGCCTTGCCGGTAGCTGTGAA
CATCCAATGCCACGCTGGCCGCCGCGCCACTGCGGTTATCTGA

Upstream 100 bases:

>100_bases
TTGACGCCGGCGCCGTGGCGCTTCCCTCGCTTCCTGGATTCGGCTTCGAAGGCAAGGCCGAATTGTGGCAAGAACTGGCT
TCACTCCAATCCTGAATATC

Downstream 100 bases:

>100_bases
GGAGCGGGCCATTATGGCAACACATCGACTCACCACGCCTCTGACGGAAGAGGCAATTCGCCAACTCAACGTTGGTGATG
AGGTACTGCTGTCTGGCACG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREIHVDTLTDAVAKLCIDACHRLPDNLVESFHKAAEKEVSPLGKSVLMKLIDNDRIARENDVSYCHDTGLAIVFVEVGQ
DVHIVGGSYEDAIQAGVRKGYAEGYMRKSVVSDPLLRVNSNDNTPAVVHTEIVPGDNIEVTVVPKGGGSENWSTMKFLLP
GEGAEGVKKFVLSAIEAAGGAACPPLTVGVGIGGSFDKVTAIAKKAILRDIGVHHKEPHVAKLEAELLDAINKTGIGPQG
YGGVNTALWVSVETYACHITALPVAVNIQCHAGRRATAVI

Sequences:

>Translated_280_residues
MREIHVDTLTDAVAKLCIDACHRLPDNLVESFHKAAEKEVSPLGKSVLMKLIDNDRIARENDVSYCHDTGLAIVFVEVGQ
DVHIVGGSYEDAIQAGVRKGYAEGYMRKSVVSDPLLRVNSNDNTPAVVHTEIVPGDNIEVTVVPKGGGSENWSTMKFLLP
GEGAEGVKKFVLSAIEAAGGAACPPLTVGVGIGGSFDKVTAIAKKAILRDIGVHHKEPHVAKLEAELLDAINKTGIGPQG
YGGVNTALWVSVETYACHITALPVAVNIQCHAGRRATAVI
>Mature_280_residues
MREIHVDTLTDAVAKLCIDACHRLPDNLVESFHKAAEKEVSPLGKSVLMKLIDNDRIARENDVSYCHDTGLAIVFVEVGQ
DVHIVGGSYEDAIQAGVRKGYAEGYMRKSVVSDPLLRVNSNDNTPAVVHTEIVPGDNIEVTVVPKGGGSENWSTMKFLLP
GEGAEGVKKFVLSAIEAAGGAACPPLTVGVGIGGSFDKVTAIAKKAILRDIGVHHKEPHVAKLEAELLDAINKTGIGPQG
YGGVNTALWVSVETYACHITALPVAVNIQCHAGRRATAVI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=33.9222614840989, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790564, Length=259, Percent_Identity=31.2741312741313, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787897, Length=257, Percent_Identity=30.7392996108949, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29658; Mature: 29658

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIHVDTLTDAVAKLCIDACHRLPDNLVESFHKAAEKEVSPLGKSVLMKLIDNDRIARE
CCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NDVSYCHDTGLAIVFVEVGQDVHIVGGSYEDAIQAGVRKGYAEGYMRKSVVSDPLLRVNS
CCCCEEECCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
NDNTPAVVHTEIVPGDNIEVTVVPKGGGSENWSTMKFLLPGEGAEGVKKFVLSAIEAAGG
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
AACPPLTVGVGIGGSFDKVTAIAKKAILRDIGVHHKEPHVAKLEAELLDAINKTGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
YGGVNTALWVSVETYACHITALPVAVNIQCHAGRRATAVI
CCCCCEEEEEEEEEEEEEEEEEEEEEEEEEECCCCEEECC
>Mature Secondary Structure
MREIHVDTLTDAVAKLCIDACHRLPDNLVESFHKAAEKEVSPLGKSVLMKLIDNDRIARE
CCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NDVSYCHDTGLAIVFVEVGQDVHIVGGSYEDAIQAGVRKGYAEGYMRKSVVSDPLLRVNS
CCCCEEECCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
NDNTPAVVHTEIVPGDNIEVTVVPKGGGSENWSTMKFLLPGEGAEGVKKFVLSAIEAAGG
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
AACPPLTVGVGIGGSFDKVTAIAKKAILRDIGVHHKEPHVAKLEAELLDAINKTGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
YGGVNTALWVSVETYACHITALPVAVNIQCHAGRRATAVI
CCCCCEEEEEEEEEEEEEEEEEEEEEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]