Click here to switch to the map view.

The map label for this gene is CYP102A1 [H]

Identifier: 94314308

GI number: 94314308

Start: 2114486

End: 2116684

Strand: Reverse

Name: CYP102A1 [H]

Synonym: Rmet_5389

Alternate gene names: 94314308

Gene position: 2116684-2114486 (Counterclockwise)

Preceding gene: 94314309

Following gene: 94314307

Centisome position: 82.04

GC content: 66.8

Gene sequence:

>2199_bases
ATGCTACGCAAGTTCCATCTGGTTCCAGGACTCGTCGCCGCGTTGCTGATGACGATCATCGCACTATCGGGCGCGGTGTT
GTCGGTGAATCCGGCGCTTGAACGTGTGGATGCCGTTCGCGCGGGCCAGGCTTCGGTAAGCGTGGCCACGCTCGCGAGCC
GCGTACAGACGGAGATCCCGGGCGTCGAAGCGCTTGCGCGGCGGCCGTCGGGGACGTTCATCGCGTATCACGAGGTCGAC
GGTCAGCAGCGCGCCTCGATCATCGACCCTGCCAGCGGCAAGGCGACGGGAGACTATGTCACCTCGCCGGTTTGGCGATG
GATGAAGAACCTGCATCGCAAGCTGTTTCTCGGCGACGCAGGCCGGATTGCGGCCGGCGTGACGGCCGCATTCATGCTGC
TCGTCACGATTTCCGGGCTGGCGTTGCTCGCGCGGCGCATGGGCGGGTGGAAGCACCTGCTCGGCCCGATCCGCGGCAAC
GGACTCCAGCGCGTGCACAACGAGACCGCGCGCGTGGCGCTGCTAGGGCTGACGCTGTCGGCGGTGACCGGGCTTGTTAT
GTCGATGACGACATTCGGGCTGATACCGGAAGGCGGCGGCCAGGACCCTGTGCTCAGCGTGCCTGCGGCGGTGGCGCCGG
CAATGCCGCTGGAGCGGATGCCCGCGCTGGGTATCGACAGCGCAGGCCTGCACCAACTGACATTCGCCCATGCCGATGCC
CAGGGCGACGTCATCGAACTGGATACGACCGACGGCGTCGGGTATGTCGATCCGGCGACGGGGAAGATGACCGCCTTCCA
GCCCACCGACGGCTGGCAGCGCGTGCAGGCGGTTGTCCGCATGTTGCATACGGGCCAGGGGATGTGGTGGCTCGGGTTGA
TGCTTGGTGCGTCGTCGCTGTCGGTGCCGGTGCTGGCAGTGACGGGCCTGCTGCTGTGGCTGCGTCGTCGGGGAACCATG
CCGACCTTGGCCGGCAATGTGCCGGCACGCGACGCGGATACGGTGTTGCTGGTGGGCTCCGAGGGCAACACCACATGGGG
CTTTGCTTCTGCGCTGCATGCCGCGTTGACCGAGGCAGGCCTGCGCGTGCATACCGCGCCGATGAATGAGCTGGCGGACA
GCTATCGTGGGAAAAAGCGGCTGCTGGTCCTGACCGCCACGTATGGCGATGGCGATGCACCCGAGAGCGCAAGTCACTTC
CTGTCGAAGCTCAATCGCCTGACGGTCCCAACCGATACCGACTTTGCGGTGCTGGGGTTCGGTGATCGCCAGTTCCCCGC
GTTCTGCGGCTATGCGAGCGCGGTGCACGATGCGCTGCTGGGCAAGGGTCTGCGAGCCCTTGCCGATCCGGGCACGGTGG
ACCGGCAGTCGGAGCCGGAATTCCGGCAATGGTGCGACTGGCTGGCCACGACGCTCGGGTTGTCGCTTGATATTCGCTAC
ACGCCGATGCTGCCACCCAGCGTGCCGCTCAAGCTCCTCTCGCGTGAGGACTACGGCGTCGGCGCTGAGGCGATGACCTC
GGTCCTGCGCTTCGTCCCAGAGCAGCGTGCCACGCCGTTCCGGCCAGGGCTGCCCACGTTCGAGACCGGGGATCTGCTCG
GCATCGTGCCGCCCGGCGCTACGTCGCCCCGGTACTACTCGCTCGCGAGCGGCGCGGCGGACGGTGTGGTGGAGATCTGC
GTGCGGCGGCTGCCTGAAGGCGTGTGTTCCACGTACCTCACAGACCTGCGCCCCGGCGACACCATCGACGCATTTATCCG
GCCGCACACGCGCTTCCGGCCCGAACCAGGCAATGCACCCGTGATCATGATCGGGGCCGGCACCGGGATCGGCCCGTTGA
TTGGCTTTATCCGGCACAACGCGGCACGCCGGCCCATGCACCTGTACTTTGGGGCGCGCAATGCCGAGGACGGCTACCTG
TATCGCGACGAGCTGAAGGGCCTGGTGGCCGACCAGCGGCTGCACGCGCTCACGACCGCGTTCTCACGTTCGGGCAACCG
GACCTATGTGCAGGAAAGACTGGTCGCCGATGCGCAGAGCCTGCGCGGGTTGATGGCCCACGGTGCGCAGATCATGGTGT
GCGGCGGCCGCAAGATGGCCGAGGGCGTGGCACAGGCGTGGGAGCGGATTCTGACGGACACCGGCTTGTCCGTCGCGCAA
CTCAAAGCGGAGGGACGCTATGTCGAGGACGTCTACTAA

Upstream 100 bases:

>100_bases
CAAGCCGGTGAGCGGCAATGGTTACGTGAAGTCGTTCCGCTACGCCTTGTAAGCAGGGCGGCCACGACAACACGCGATAA
AGGAAAAAGGAGGTCCACCG

Downstream 100 bases:

>100_bases
TCGGTCAGACACGGCGCTCGAACTCTGTCGCGTCAGCGGCGCGACCATGGGCACCCGCTACACGGCGGCATACTACGCGC
CGCCGGGCATGGATGAAGCG

Product: oxidoreductase FAD/NAD(P)-binding

Products: NA

Alternate protein names: Cytochrome P450(BM-3); Cytochrome P450BM-3; Cytochrome P450 102; NADPH--cytochrome P450 reductase [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MLRKFHLVPGLVAALLMTIIALSGAVLSVNPALERVDAVRAGQASVSVATLASRVQTEIPGVEALARRPSGTFIAYHEVD
GQQRASIIDPASGKATGDYVTSPVWRWMKNLHRKLFLGDAGRIAAGVTAAFMLLVTISGLALLARRMGGWKHLLGPIRGN
GLQRVHNETARVALLGLTLSAVTGLVMSMTTFGLIPEGGGQDPVLSVPAAVAPAMPLERMPALGIDSAGLHQLTFAHADA
QGDVIELDTTDGVGYVDPATGKMTAFQPTDGWQRVQAVVRMLHTGQGMWWLGLMLGASSLSVPVLAVTGLLLWLRRRGTM
PTLAGNVPARDADTVLLVGSEGNTTWGFASALHAALTEAGLRVHTAPMNELADSYRGKKRLLVLTATYGDGDAPESASHF
LSKLNRLTVPTDTDFAVLGFGDRQFPAFCGYASAVHDALLGKGLRALADPGTVDRQSEPEFRQWCDWLATTLGLSLDIRY
TPMLPPSVPLKLLSREDYGVGAEAMTSVLRFVPEQRATPFRPGLPTFETGDLLGIVPPGATSPRYYSLASGAADGVVEIC
VRRLPEGVCSTYLTDLRPGDTIDAFIRPHTRFRPEPGNAPVIMIGAGTGIGPLIGFIRHNAARRPMHLYFGARNAEDGYL
YRDELKGLVADQRLHALTTAFSRSGNRTYVQERLVADAQSLRGLMAHGAQIMVCGGRKMAEGVAQAWERILTDTGLSVAQ
LKAEGRYVEDVY

Sequences:

>Translated_732_residues
MLRKFHLVPGLVAALLMTIIALSGAVLSVNPALERVDAVRAGQASVSVATLASRVQTEIPGVEALARRPSGTFIAYHEVD
GQQRASIIDPASGKATGDYVTSPVWRWMKNLHRKLFLGDAGRIAAGVTAAFMLLVTISGLALLARRMGGWKHLLGPIRGN
GLQRVHNETARVALLGLTLSAVTGLVMSMTTFGLIPEGGGQDPVLSVPAAVAPAMPLERMPALGIDSAGLHQLTFAHADA
QGDVIELDTTDGVGYVDPATGKMTAFQPTDGWQRVQAVVRMLHTGQGMWWLGLMLGASSLSVPVLAVTGLLLWLRRRGTM
PTLAGNVPARDADTVLLVGSEGNTTWGFASALHAALTEAGLRVHTAPMNELADSYRGKKRLLVLTATYGDGDAPESASHF
LSKLNRLTVPTDTDFAVLGFGDRQFPAFCGYASAVHDALLGKGLRALADPGTVDRQSEPEFRQWCDWLATTLGLSLDIRY
TPMLPPSVPLKLLSREDYGVGAEAMTSVLRFVPEQRATPFRPGLPTFETGDLLGIVPPGATSPRYYSLASGAADGVVEIC
VRRLPEGVCSTYLTDLRPGDTIDAFIRPHTRFRPEPGNAPVIMIGAGTGIGPLIGFIRHNAARRPMHLYFGARNAEDGYL
YRDELKGLVADQRLHALTTAFSRSGNRTYVQERLVADAQSLRGLMAHGAQIMVCGGRKMAEGVAQAWERILTDTGLSVAQ
LKAEGRYVEDVY
>Mature_732_residues
MLRKFHLVPGLVAALLMTIIALSGAVLSVNPALERVDAVRAGQASVSVATLASRVQTEIPGVEALARRPSGTFIAYHEVD
GQQRASIIDPASGKATGDYVTSPVWRWMKNLHRKLFLGDAGRIAAGVTAAFMLLVTISGLALLARRMGGWKHLLGPIRGN
GLQRVHNETARVALLGLTLSAVTGLVMSMTTFGLIPEGGGQDPVLSVPAAVAPAMPLERMPALGIDSAGLHQLTFAHADA
QGDVIELDTTDGVGYVDPATGKMTAFQPTDGWQRVQAVVRMLHTGQGMWWLGLMLGASSLSVPVLAVTGLLLWLRRRGTM
PTLAGNVPARDADTVLLVGSEGNTTWGFASALHAALTEAGLRVHTAPMNELADSYRGKKRLLVLTATYGDGDAPESASHF
LSKLNRLTVPTDTDFAVLGFGDRQFPAFCGYASAVHDALLGKGLRALADPGTVDRQSEPEFRQWCDWLATTLGLSLDIRY
TPMLPPSVPLKLLSREDYGVGAEAMTSVLRFVPEQRATPFRPGLPTFETGDLLGIVPPGATSPRYYSLASGAADGVVEIC
VRRLPEGVCSTYLTDLRPGDTIDAFIRPHTRFRPEPGNAPVIMIGAGTGIGPLIGFIRHNAARRPMHLYFGARNAEDGYL
YRDELKGLVADQRLHALTTAFSRSGNRTYVQERLVADAQSLRGLMAHGAQIMVCGGRKMAEGVAQAWERILTDTGLSVAQ
LKAEGRYVEDVY

Specific function: Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is re

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI40254422, Length=226, Percent_Identity=34.9557522123894, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI127139033, Length=224, Percent_Identity=33.9285714285714, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI24041029, Length=237, Percent_Identity=30.8016877637131, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI10835173, Length=224, Percent_Identity=31.6964285714286, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI169790958, Length=165, Percent_Identity=31.5151515151515, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI169790956, Length=165, Percent_Identity=31.5151515151515, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1789123, Length=216, Percent_Identity=32.8703703703704, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554134, Length=191, Percent_Identity=34.5549738219895, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17566446, Length=168, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325305, Length=169, Percent_Identity=27.810650887574, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321832, Length=171, Percent_Identity=34.5029239766082, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582192, Length=225, Percent_Identity=30.6666666666667, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17137192, Length=225, Percent_Identity=30.6666666666667, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583543, Length=224, Percent_Identity=32.5892857142857, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706876, Length=224, Percent_Identity=32.5892857142857, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706872, Length=224, Percent_Identity=32.5892857142857, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023206
- InterPro:   IPR001128
- InterPro:   IPR015702
- InterPro:   IPR017972
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1; PF00067 p450 [H]

EC number: =1.14.14.1; =1.6.2.4 [H]

Molecular weight: Translated: 78313; Mature: 78313

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKFHLVPGLVAALLMTIIALSGAVLSVNPALERVDAVRAGQASVSVATLASRVQTEIP
CCCEECCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GVEALARRPSGTFIAYHEVDGQQRASIIDPASGKATGDYVTSPVWRWMKNLHRKLFLGDA
CHHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHEECCCC
GRIAAGVTAAFMLLVTISGLALLARRMGGWKHLLGPIRGNGLQRVHNETARVALLGLTLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHEEHHHHHHH
AVTGLVMSMTTFGLIPEGGGQDPVLSVPAAVAPAMPLERMPALGIDSAGLHQLTFAHADA
HHHHHHHHHHHHCCCCCCCCCCCCEECCHHHCCCCCHHHCCCCCCCCCCCHHEEEEECCC
QGDVIELDTTDGVGYVDPATGKMTAFQPTDGWQRVQAVVRMLHTGQGMWWLGLMLGASSL
CCCEEEEECCCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
SVPVLAVTGLLLWLRRRGTMPTLAGNVPARDADTVLLVGSEGNTTWGFASALHAALTEAG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
LRVHTAPMNELADSYRGKKRLLVLTATYGDGDAPESASHFLSKLNRLTVPTDTDFAVLGF
CEEEECCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEC
GDRQFPAFCGYASAVHDALLGKGLRALADPGTVDRQSEPEFRQWCDWLATTLGLSLDIRY
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEE
TPMLPPSVPLKLLSREDYGVGAEAMTSVLRFVPEQRATPFRPGLPTFETGDLLGIVPPGA
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCEEEEECCCC
TSPRYYSLASGAADGVVEICVRRLPEGVCSTYLTDLRPGDTIDAFIRPHTRFRPEPGNAP
CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCC
VIMIGAGTGIGPLIGFIRHNAARRPMHLYFGARNAEDGYLYRDELKGLVADQRLHALTTA
EEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHH
FSRSGNRTYVQERLVADAQSLRGLMAHGAQIMVCGGRKMAEGVAQAWERILTDTGLSVAQ
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
LKAEGRYVEDVY
HHHCCCCCCCCC
>Mature Secondary Structure
MLRKFHLVPGLVAALLMTIIALSGAVLSVNPALERVDAVRAGQASVSVATLASRVQTEIP
CCCEECCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GVEALARRPSGTFIAYHEVDGQQRASIIDPASGKATGDYVTSPVWRWMKNLHRKLFLGDA
CHHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHEECCCC
GRIAAGVTAAFMLLVTISGLALLARRMGGWKHLLGPIRGNGLQRVHNETARVALLGLTLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHEEHHHHHHH
AVTGLVMSMTTFGLIPEGGGQDPVLSVPAAVAPAMPLERMPALGIDSAGLHQLTFAHADA
HHHHHHHHHHHHCCCCCCCCCCCCEECCHHHCCCCCHHHCCCCCCCCCCCHHEEEEECCC
QGDVIELDTTDGVGYVDPATGKMTAFQPTDGWQRVQAVVRMLHTGQGMWWLGLMLGASSL
CCCEEEEECCCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
SVPVLAVTGLLLWLRRRGTMPTLAGNVPARDADTVLLVGSEGNTTWGFASALHAALTEAG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
LRVHTAPMNELADSYRGKKRLLVLTATYGDGDAPESASHFLSKLNRLTVPTDTDFAVLGF
CEEEECCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEC
GDRQFPAFCGYASAVHDALLGKGLRALADPGTVDRQSEPEFRQWCDWLATTLGLSLDIRY
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEE
TPMLPPSVPLKLLSREDYGVGAEAMTSVLRFVPEQRATPFRPGLPTFETGDLLGIVPPGA
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCEEEEECCCC
TSPRYYSLASGAADGVVEICVRRLPEGVCSTYLTDLRPGDTIDAFIRPHTRFRPEPGNAP
CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCC
VIMIGAGTGIGPLIGFIRHNAARRPMHLYFGARNAEDGYLYRDELKGLVADQRLHALTTA
EEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHH
FSRSGNRTYVQERLVADAQSLRGLMAHGAQIMVCGGRKMAEGVAQAWERILTDTGLSVAQ
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
LKAEGRYVEDVY
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544578; 1727637; 8342039; 9033595; 10051560; 11695892 [H]