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The map label for this gene is apbE [H]

Identifier: 94314307

GI number: 94314307

Start: 2113516

End: 2114505

Strand: Reverse

Name: apbE [H]

Synonym: Rmet_5388

Alternate gene names: 94314307

Gene position: 2114505-2113516 (Counterclockwise)

Preceding gene: 94314308

Following gene: 94314305

Centisome position: 81.95

GC content: 68.08

Gene sequence:

>990_bases
ATGTCGAGGACGTCTACTAATCGGTCAGACACGGCGCTCGAACTCTGTCGCGTCAGCGGCGCGACCATGGGCACCCGCTA
CACGGCGGCATACTACGCGCCGCCGGGCATGGATGAAGCGGTGCTGGCGGAACGACTCGCCCTGGCGGTCGGCGCCGTGG
ATGCGCAGATGTCGAACTGGAAGGCAGACTCGGATCTGTCCCGACTGAACCGTGCTGCGCCGGGCGGTTGGGTGCCGGTC
TCCAGGAACCTCGCAACCCTGCTTGCGCGGGCGCTGAAGATCGGCAGTGATACGCACAACGCGTTCAACATCGGCGTCGG
CGATCTGGTCGACCGGTGGGGGTTCGGACCGTCCGGGGCGCAATGCGTTTCGCATCCAGATCTCGGTGAGGCGGCCGGCG
CAAGTCCCCGCCAGCCAGCAGGAGAACTGATCGAGGTGGATGAGCGGCTGTGCCGCGTGCGCAAGCTCGGCCCGGTCGTG
CTCGATCTGTGTGGCATCGCCAAGGGGTTTGGCGTCGATGAACTCGGGCGTGTGCTGAGCGAGCACGGTATCGAATCCTG
GCTGGTCGGCATCGACGGCGAGATGCGCGCGCGTGGGAATAAGCCAGATGGCGGGCCGTGGGCGATCGCCCTCGAGGCCC
CGGACTATGAGCGCCGCGCGGCGATGGGCGTGATCGAACTGGCAGATGCCGCCATTGCCACGTCCGGCGATTACCGGCGC
TGGGCCGATGTCGGCGGCGCGCGCATTTCGCACACGATGGACCCGCGTACCGGTGCGCCGCTGGCGGGTGGGATGGCATC
GGTCACGGTGGTGGCGAAGACCTGCGCGGATGCCGATGCCTATGCGACGGCGCTGATGGTGCTCGGCGCGCAGGCTGGGC
CGGACTACGCGCGGCAGCGCGGCCTCGACGTCCTCTTCATCGTGCGCGATGGCGAGGCGCTGCGCACGATCGGAACCGGA
TGCTTTGCGGACGAGGCGCCGTCAAGCTGA

Upstream 100 bases:

>100_bases
TGCGGCGGCCGCAAGATGGCCGAGGGCGTGGCACAGGCGTGGGAGCGGATTCTGACGGACACCGGCTTGTCCGTCGCGCA
ACTCAAAGCGGAGGGACGCT

Downstream 100 bases:

>100_bases
CACGGCACTAGCGCGATTCGCGCCCCGAGCGCCGCGCCGCCAGCCCGCTCCACACGGTCGCCCACGCAAAGGGGCGCGGG
TCGGCCAACATGCTCATGGC

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSRTSTNRSDTALELCRVSGATMGTRYTAAYYAPPGMDEAVLAERLALAVGAVDAQMSNWKADSDLSRLNRAAPGGWVPV
SRNLATLLARALKIGSDTHNAFNIGVGDLVDRWGFGPSGAQCVSHPDLGEAAGASPRQPAGELIEVDERLCRVRKLGPVV
LDLCGIAKGFGVDELGRVLSEHGIESWLVGIDGEMRARGNKPDGGPWAIALEAPDYERRAAMGVIELADAAIATSGDYRR
WADVGGARISHTMDPRTGAPLAGGMASVTVVAKTCADADAYATALMVLGAQAGPDYARQRGLDVLFIVRDGEALRTIGTG
CFADEAPSS

Sequences:

>Translated_329_residues
MSRTSTNRSDTALELCRVSGATMGTRYTAAYYAPPGMDEAVLAERLALAVGAVDAQMSNWKADSDLSRLNRAAPGGWVPV
SRNLATLLARALKIGSDTHNAFNIGVGDLVDRWGFGPSGAQCVSHPDLGEAAGASPRQPAGELIEVDERLCRVRKLGPVV
LDLCGIAKGFGVDELGRVLSEHGIESWLVGIDGEMRARGNKPDGGPWAIALEAPDYERRAAMGVIELADAAIATSGDYRR
WADVGGARISHTMDPRTGAPLAGGMASVTVVAKTCADADAYATALMVLGAQAGPDYARQRGLDVLFIVRDGEALRTIGTG
CFADEAPSS
>Mature_328_residues
SRTSTNRSDTALELCRVSGATMGTRYTAAYYAPPGMDEAVLAERLALAVGAVDAQMSNWKADSDLSRLNRAAPGGWVPVS
RNLATLLARALKIGSDTHNAFNIGVGDLVDRWGFGPSGAQCVSHPDLGEAAGASPRQPAGELIEVDERLCRVRKLGPVVL
DLCGIAKGFGVDELGRVLSEHGIESWLVGIDGEMRARGNKPDGGPWAIALEAPDYERRAAMGVIELADAAIATSGDYRRW
ADVGGARISHTMDPRTGAPLAGGMASVTVVAKTCADADAYATALMVLGAQAGPDYARQRGLDVLFIVRDGEALRTIGTGC
FADEAPSS

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=316, Percent_Identity=33.2278481012658, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34425; Mature: 34294

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTSTNRSDTALELCRVSGATMGTRYTAAYYAPPGMDEAVLAERLALAVGAVDAQMSNW
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KADSDLSRLNRAAPGGWVPVSRNLATLLARALKIGSDTHNAFNIGVGDLVDRWGFGPSGA
CCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCCC
QCVSHPDLGEAAGASPRQPAGELIEVDERLCRVRKLGPVVLDLCGIAKGFGVDELGRVLS
CCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EHGIESWLVGIDGEMRARGNKPDGGPWAIALEAPDYERRAAMGVIELADAAIATSGDYRR
HCCHHHEEEECCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHH
WADVGGARISHTMDPRTGAPLAGGMASVTVVAKTCADADAYATALMVLGAQAGPDYARQR
HHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHC
GLDVLFIVRDGEALRTIGTGCFADEAPSS
CCEEEEEEECCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SRTSTNRSDTALELCRVSGATMGTRYTAAYYAPPGMDEAVLAERLALAVGAVDAQMSNW
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KADSDLSRLNRAAPGGWVPVSRNLATLLARALKIGSDTHNAFNIGVGDLVDRWGFGPSGA
CCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCCC
QCVSHPDLGEAAGASPRQPAGELIEVDERLCRVRKLGPVVLDLCGIAKGFGVDELGRVLS
CCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EHGIESWLVGIDGEMRARGNKPDGGPWAIALEAPDYERRAAMGVIELADAAIATSGDYRR
HCCHHHEEEECCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHH
WADVGGARISHTMDPRTGAPLAGGMASVTVVAKTCADADAYATALMVLGAQAGPDYARQR
HHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHC
GLDVLFIVRDGEALRTIGTGCFADEAPSS
CCEEEEEEECCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]