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The map label for this gene is gbpR [H]

Identifier: 94314113

GI number: 94314113

Start: 1888600

End: 1889664

Strand: Reverse

Name: gbpR [H]

Synonym: Rmet_5194

Alternate gene names: 94314113

Gene position: 1889664-1888600 (Counterclockwise)

Preceding gene: 94314117

Following gene: 94314112

Centisome position: 73.24

GC content: 64.41

Gene sequence:

>1065_bases
ATGTGTGTGCGCTATACGGCACGTATATGGCGGAAAATCGCCGGCTGCCCGCGCAGGACTTCTCAACTTTGTGATTCCGA
GGCTCAAATGTCCGTCAATCCACTCAGCGAGATCTCGCTGATTCGCAGGTTGAAGCTGAACCAACTGATGATCTTCGAGC
GCGTGCTGCAGACGCGCTCGGTGATGCGCGCCGCCAATGACATGCGTCTGACGCAGCCAGCCGTGACCAAGGTGATTCAC
GAACTGGAGTCTTGCTTCGATGGCGCGCTATTCCTGCGTTCCAACCGCGGCGTGATGCCGACGGAGCTTGGGCTGCTGCT
CGGCCAGCGCGTCAAGTCGCTGATGGCCGAACTGCGCTACATGACCGACGAGCTGAATGATTTCCGCTTGGGGACCAGCG
GACACGTCATCGTCGGCACGCTGATCTCGGCATCGGCACGACTGTTGCCGCTGGCCATCTCCATGCTCAAGTCGCGCACG
CCGAACGTACTGGTGACCGTGCGCGAAGGCACCACCGCCCACTTGTTTCCGGCGCTGGCCACGGGAGACCTCGACATCGT
CGTCGGCCGCCTTCCCGAGCGTGAACTGCCGATTGCCACGGCCTTCCCGCTGACGCATGAGGTGTTGTTCGAGGAGTCGC
TCTGCGCGGTGGTCGGCAAGGGCTACGGCGACGCGCCGGATCGCGTGGGGCACCTGTCCGAGCTGGCCGATTCGGCGTGG
ATACTCCCGACGTCCGACTCTCCGGCACGCCTGGCAGCGGAGCAGCTTTTCCGTACTGCCGGCCTGCCGCTGCCAGGGGA
CGTCGTCGAGTCGCTGTCGCTGCTGACCAACCTTGGGCTGCTGATGGAGACCCCGCGCATTGCACTGATGCCAAGCGTGG
CGGCGAACCAGTTCGCGCGCGCCGGCCTGTTGCGCGTCCTCGACCTGCCGGAGACCTGCGCCTTCGGCACGGTTGGATTC
TCGGTGCGTTCGAACAAGGAACAGAGCGCGGCGGGCCGTGCATTCATCGCTTGCCTGCGAGAGGCCGCGCAGGCAAGCGT
GCCCGACGTGCCGCTGCCTTGTTGA

Upstream 100 bases:

>100_bases
GTATACTCGGGAGTTACAAATTATACGTAGACGAGTATGTGTATTCCGATGATTATTTTCTTATACACAGAGGGGGTTTG
GTAATAGCGGGTTGACCCGA

Downstream 100 bases:

>100_bases
GTGACACATTCCGAAAGGGTGGCTTCGGGACGCGCTGGTATTCCTGTTCGGGATAGCCAGCGCCGGATGTTTGATTATCG
AGGCCGGCGTGGCTCCCCTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MCVRYTARIWRKIAGCPRRTSQLCDSEAQMSVNPLSEISLIRRLKLNQLMIFERVLQTRSVMRAANDMRLTQPAVTKVIH
ELESCFDGALFLRSNRGVMPTELGLLLGQRVKSLMAELRYMTDELNDFRLGTSGHVIVGTLISASARLLPLAISMLKSRT
PNVLVTVREGTTAHLFPALATGDLDIVVGRLPERELPIATAFPLTHEVLFEESLCAVVGKGYGDAPDRVGHLSELADSAW
ILPTSDSPARLAAEQLFRTAGLPLPGDVVESLSLLTNLGLLMETPRIALMPSVAANQFARAGLLRVLDLPETCAFGTVGF
SVRSNKEQSAAGRAFIACLREAAQASVPDVPLPC

Sequences:

>Translated_354_residues
MCVRYTARIWRKIAGCPRRTSQLCDSEAQMSVNPLSEISLIRRLKLNQLMIFERVLQTRSVMRAANDMRLTQPAVTKVIH
ELESCFDGALFLRSNRGVMPTELGLLLGQRVKSLMAELRYMTDELNDFRLGTSGHVIVGTLISASARLLPLAISMLKSRT
PNVLVTVREGTTAHLFPALATGDLDIVVGRLPERELPIATAFPLTHEVLFEESLCAVVGKGYGDAPDRVGHLSELADSAW
ILPTSDSPARLAAEQLFRTAGLPLPGDVVESLSLLTNLGLLMETPRIALMPSVAANQFARAGLLRVLDLPETCAFGTVGF
SVRSNKEQSAAGRAFIACLREAAQASVPDVPLPC
>Mature_354_residues
MCVRYTARIWRKIAGCPRRTSQLCDSEAQMSVNPLSEISLIRRLKLNQLMIFERVLQTRSVMRAANDMRLTQPAVTKVIH
ELESCFDGALFLRSNRGVMPTELGLLLGQRVKSLMAELRYMTDELNDFRLGTSGHVIVGTLISASARLLPLAISMLKSRT
PNVLVTVREGTTAHLFPALATGDLDIVVGRLPERELPIATAFPLTHEVLFEESLCAVVGKGYGDAPDRVGHLSELADSAW
ILPTSDSPARLAAEQLFRTAGLPLPGDVVESLSLLTNLGLLMETPRIALMPSVAANQFARAGLLRVLDLPETCAFGTVGF
SVRSNKEQSAAGRAFIACLREAAQASVPDVPLPC

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=237, Percent_Identity=27.4261603375527, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789506, Length=285, Percent_Identity=24.5614035087719, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081904, Length=308, Percent_Identity=25.3246753246753, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=24.9134948096886, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=239, Percent_Identity=25.5230125523013, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081766, Length=294, Percent_Identity=23.469387755102, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38485; Mature: 38485

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVRYTARIWRKIAGCPRRTSQLCDSEAQMSVNPLSEISLIRRLKLNQLMIFERVLQTRS
CCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRAANDMRLTQPAVTKVIHELESCFDGALFLRSNRGVMPTELGLLLGQRVKSLMAELRY
HHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
MTDELNDFRLGTSGHVIVGTLISASARLLPLAISMLKSRTPNVLVTVREGTTAHLFPALA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TGDLDIVVGRLPERELPIATAFPLTHEVLFEESLCAVVGKGYGDAPDRVGHLSELADSAW
CCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCE
ILPTSDSPARLAAEQLFRTAGLPLPGDVVESLSLLTNLGLLMETPRIALMPSVAANQFAR
EEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
AGLLRVLDLPETCAFGTVGFSVRSNKEQSAAGRAFIACLREAAQASVPDVPLPC
HHHHHHHCCCCHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCVRYTARIWRKIAGCPRRTSQLCDSEAQMSVNPLSEISLIRRLKLNQLMIFERVLQTRS
CCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRAANDMRLTQPAVTKVIHELESCFDGALFLRSNRGVMPTELGLLLGQRVKSLMAELRY
HHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
MTDELNDFRLGTSGHVIVGTLISASARLLPLAISMLKSRTPNVLVTVREGTTAHLFPALA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TGDLDIVVGRLPERELPIATAFPLTHEVLFEESLCAVVGKGYGDAPDRVGHLSELADSAW
CCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCE
ILPTSDSPARLAAEQLFRTAGLPLPGDVVESLSLLTNLGLLMETPRIALMPSVAANQFAR
EEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
AGLLRVLDLPETCAFGTVGFSVRSNKEQSAAGRAFIACLREAAQASVPDVPLPC
HHHHHHHCCCCHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]