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The map label for this gene is mmgC [H]

Identifier: 94314071

GI number: 94314071

Start: 1850580

End: 1851725

Strand: Reverse

Name: mmgC [H]

Synonym: Rmet_5152

Alternate gene names: 94314071

Gene position: 1851725-1850580 (Counterclockwise)

Preceding gene: 94314072

Following gene: 94314067

Centisome position: 71.77

GC content: 62.13

Gene sequence:

>1146_bases
ATGACCAACCCTTTGCCCTGGATCAGCGGCGACCTGGAGATCTTCCAGGATGGCATTCGCAAGTTCGTCGAGCGCGAGCT
TGCACCCAACGAGGATCGTTGGTGGAAGCAGCAGTACATCGACCGTGAAGTCTGGTACAAGGCAGGCGAGATGGGGATGC
TCTGCGCAAGCATTCCCGAAGAGTACGGTGGCGGCGGCGGGACGTTCGCCCACGAGGCCATCATCACGATGGAACAGGGG
CGGGCCGGCGTGAGCAGCCTCGGCACCAACGTGCACAGCGGCATCGTTGCCCACTACATCCTGCGCTACGGCACTGAGGA
ACAGAAACGCAAGTGGCTGCCGAAGATGGCGACGGGCGAGCTGGTTGCCGCCATCGCCATGTCGGAACCCGGCGCGGGTT
CGGATCTCAAGAGCGTCAAGACGCGCGCGCTGAAGGAGGGCGACAGCTACGTCATCAATGGTTCGAAGACCTTCATCACG
AACGGCTATCACGCGAACCTGATCCTGGTGATCTGCAAGACCGATCCCGAGGCGGGCGCGCGCGGCGTGTCGATCGTCGT
GGTCGAGACCGATGGCCAGCAGGGATTCCGCCGCGGTCGCATCCTGGAAAAGATGGGGCAGAAGGGCCAGGACACCGCCG
AGTTGTTCTTCGACGACATGCGCGTGCCGTGCGCGAACCTGCTCGGCACCGAAGAGGGCAAGGGCTTCTACCAGCTCATG
CAACAGTTGCCGCAGGAGCGCATGATCATCGCGCTGGGCGCGTTGGCATCGATGGAGCGCGCGCTGGGCCTGACGATCGA
GTACGTGCGCAATCGCAAGGTCTTCGGCGAATCACTGATCGAGCTGCAGAACACCCGATTCCGGTTGGCGGAGTGCAAGA
CCAACGCGACCATCGCGCGCAGCTTCGTCAACGATTGCATGGAGAAAATCCTGCGTGGGGAGCTGGACCCCGGCACGGCG
GCGATGGCCAAGTGGTGGTGCACGCAGCGTTCGTGCGAGATCATCGACGAATGCCTGCAGTTGCACGGCGGCTATGGCTA
CATGATGGAGTACCCGATTGCGCGGATGTATGTGAACGCGCGGGTCAGCAAGATCTACGGTGGCTCGAACGAGATCATGA
AGGAACTGATCGCGCGCGAACTCTGA

Upstream 100 bases:

>100_bases
CGCTGGGGCGAGACCATCCGCCTCGCCAACCTGACACTCGACTGATGACGCTGTCATCGTTCAACGCATCCAACACAATC
GAAGCAGGAGACATCGCATC

Downstream 100 bases:

>100_bases
GGTGCTGCCGGCGAGGCGAAGTCGCTACGGTTTCGGTCAGGGTCCTTTTTCGATCCGGGCCGAAGCCTACGCGGCCGGCG
CGTCGCCGGCAAATTCCGCA

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTNPLPWISGDLEIFQDGIRKFVERELAPNEDRWWKQQYIDREVWYKAGEMGMLCASIPEEYGGGGGTFAHEAIITMEQG
RAGVSSLGTNVHSGIVAHYILRYGTEEQKRKWLPKMATGELVAAIAMSEPGAGSDLKSVKTRALKEGDSYVINGSKTFIT
NGYHANLILVICKTDPEAGARGVSIVVVETDGQQGFRRGRILEKMGQKGQDTAELFFDDMRVPCANLLGTEEGKGFYQLM
QQLPQERMIIALGALASMERALGLTIEYVRNRKVFGESLIELQNTRFRLAECKTNATIARSFVNDCMEKILRGELDPGTA
AMAKWWCTQRSCEIIDECLQLHGGYGYMMEYPIARMYVNARVSKIYGGSNEIMKELIAREL

Sequences:

>Translated_381_residues
MTNPLPWISGDLEIFQDGIRKFVERELAPNEDRWWKQQYIDREVWYKAGEMGMLCASIPEEYGGGGGTFAHEAIITMEQG
RAGVSSLGTNVHSGIVAHYILRYGTEEQKRKWLPKMATGELVAAIAMSEPGAGSDLKSVKTRALKEGDSYVINGSKTFIT
NGYHANLILVICKTDPEAGARGVSIVVVETDGQQGFRRGRILEKMGQKGQDTAELFFDDMRVPCANLLGTEEGKGFYQLM
QQLPQERMIIALGALASMERALGLTIEYVRNRKVFGESLIELQNTRFRLAECKTNATIARSFVNDCMEKILRGELDPGTA
AMAKWWCTQRSCEIIDECLQLHGGYGYMMEYPIARMYVNARVSKIYGGSNEIMKELIAREL
>Mature_380_residues
TNPLPWISGDLEIFQDGIRKFVERELAPNEDRWWKQQYIDREVWYKAGEMGMLCASIPEEYGGGGGTFAHEAIITMEQGR
AGVSSLGTNVHSGIVAHYILRYGTEEQKRKWLPKMATGELVAAIAMSEPGAGSDLKSVKTRALKEGDSYVINGSKTFITN
GYHANLILVICKTDPEAGARGVSIVVVETDGQQGFRRGRILEKMGQKGQDTAELFFDDMRVPCANLLGTEEGKGFYQLMQ
QLPQERMIIALGALASMERALGLTIEYVRNRKVFGESLIELQNTRFRLAECKTNATIARSFVNDCMEKILRGELDPGTAA
MAKWWCTQRSCEIIDECLQLHGGYGYMMEYPIARMYVNARVSKIYGGSNEIMKELIAREL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=47.6063829787234, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI226958412, Length=370, Percent_Identity=34.5945945945946, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=34.402332361516, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=34.5945945945946, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=34.3243243243243, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=29.5514511873351, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI4557231, Length=371, Percent_Identity=32.6145552560647, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI187960098, Length=371, Percent_Identity=32.6145552560647, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI21361497, Length=396, Percent_Identity=32.3232323232323, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4557235, Length=358, Percent_Identity=33.2402234636872, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI76496475, Length=358, Percent_Identity=33.2402234636872, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=27.4869109947644, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=27.7929155313352, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI48976061, Length=292, Percent_Identity=30.1369863013699, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=292, Percent_Identity=30.1369863013699, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38505218, Length=289, Percent_Identity=26.9896193771626, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=29.0666666666667, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081958, Length=341, Percent_Identity=28.4457478005865, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081702, Length=402, Percent_Identity=24.3781094527363, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082384, Length=268, Percent_Identity=29.4776119402985, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=34.9333333333333, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=34.4, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=33.3333333333333, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=32.0652173913043, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=31.8918918918919, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=32.5268817204301, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=380, Percent_Identity=30.7894736842105, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=32.6027397260274, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=30.7894736842105, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=32.3033707865169, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=34.8591549295775, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=33.920704845815, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=314, Percent_Identity=32.484076433121, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=370, Percent_Identity=25.1351351351351, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=334, Percent_Identity=28.1437125748503, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=26.9709543568465, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355753, Length=365, Percent_Identity=35.3424657534247, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=32.5396825396825, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=33.4190231362468, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=31.5363881401617, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24666513, Length=378, Percent_Identity=28.8359788359788, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=32, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=27.3458445040214, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42614; Mature: 42482

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPLPWISGDLEIFQDGIRKFVERELAPNEDRWWKQQYIDREVWYKAGEMGMLCASIPE
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHCCCCCHHHHHCCH
EYGGGGGTFAHEAIITMEQGRAGVSSLGTNVHSGIVAHYILRYGTEEQKRKWLPKMATGE
HHCCCCCCCHHHHEEEECCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCH
LVAAIAMSEPGAGSDLKSVKTRALKEGDSYVINGSKTFITNGYHANLILVICKTDPEAGA
HHHHEEECCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCC
RGVSIVVVETDGQQGFRRGRILEKMGQKGQDTAELFFDDMRVPCANLLGTEEGKGFYQLM
CCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHH
QQLPQERMIIALGALASMERALGLTIEYVRNRKVFGESLIELQNTRFRLAECKTNATIAR
HHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHH
SFVNDCMEKILRGELDPGTAAMAKWWCTQRSCEIIDECLQLHGGYGYMMEYPIARMYVNA
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCHHHHHHHHH
RVSKIYGGSNEIMKELIAREL
HHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TNPLPWISGDLEIFQDGIRKFVERELAPNEDRWWKQQYIDREVWYKAGEMGMLCASIPE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHCCCCCHHHHHCCH
EYGGGGGTFAHEAIITMEQGRAGVSSLGTNVHSGIVAHYILRYGTEEQKRKWLPKMATGE
HHCCCCCCCHHHHEEEECCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCH
LVAAIAMSEPGAGSDLKSVKTRALKEGDSYVINGSKTFITNGYHANLILVICKTDPEAGA
HHHHEEECCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCC
RGVSIVVVETDGQQGFRRGRILEKMGQKGQDTAELFFDDMRVPCANLLGTEEGKGFYQLM
CCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHH
QQLPQERMIIALGALASMERALGLTIEYVRNRKVFGESLIELQNTRFRLAECKTNATIAR
HHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHH
SFVNDCMEKILRGELDPGTAAMAKWWCTQRSCEIIDECLQLHGGYGYMMEYPIARMYVNA
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCHHHHHHHHH
RVSKIYGGSNEIMKELIAREL
HHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]