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The map label for this gene is crt [H]

Identifier: 94314069

GI number: 94314069

Start: 1848601

End: 1849395

Strand: Direct

Name: crt [H]

Synonym: Rmet_5150

Alternate gene names: 94314069

Gene position: 1848601-1849395 (Clockwise)

Preceding gene: 94314068

Following gene: 94314070

Centisome position: 71.65

GC content: 64.28

Gene sequence:

>795_bases
ATGTCGAACTTCCTGTCCTACGAACAAGACGGGCACGTCGTCACGTTGACGATGTCGGAACCCGAGCGCCGGAACCCACT
GACGGGCAATACGGCCGTGCCCGAATTCCTGGCCGCGATCGAGCGTATCGAGTCCGATACGTCGGTCCGCGCCGTGATCA
TCACCGGAAGCGGTACCGCATTCTCGTCGGGCGGCAACATCCACGAAATGAAGCGGCAGGCATCCGGGACTGCCTCGGCA
ATGGACGTCAGACGGGACTATCGCCATGGCATTCAGCGGCTGCCGCTTGCGCTGTTCAATCTGGAGGTCCCGGTCATCGC
CGCCGTCAACGGTCCGGCACTGGGGGCGGGTCTCGATCTCACCTGCATGTGCGACATCCGCATCGCGTCGCGCGCCGCCC
AGTTTGCGGAGAGCTTCGTCAAGCTGGGCATCATTCCCGGGGATGGCGGCGCCTGGCTGCTGCCCCGAATCATCGGGATG
TCGCGCGCGGCGGAGCTTACGTTCACGGGCAAGGCGATCGACGCGCAAACGGCGCTCGAGTGGAATCTCGTTTCGCAGGT
AGTCGAACCTGAGGCTCTGCTGCCCACGGCCCGGGAGATCGCGGCCGCCATCGCGGCAAACCCGCCGCACGCGGTCCGAT
TGGCCAAGCGCCTGTTGCGCGAAGGCATGCACACGTCGCTGGGCACGCTGCTGGAACTTTCCGCCGTCTATCAAGCGGTC
TCGCATCAGGCCGCCGATCACAAGGAAGCCGTGGAAGCGTTCCTCGACAAGCGCAAACCCGTATTCAAGGGATAA

Upstream 100 bases:

>100_bases
GGAGATCAAGAAGTGGTCGGACGCCGCCGAGCGCGCAGGCGTGCCGAAACAGTAGACGCAACGATAGACGAACCGATCCA
TCCAATCCCGGAGACCTACC

Downstream 100 bases:

>100_bases
AGGGGTCACGACAGGCCGTTTCTCGTTCCGGCGTGGCGGCGGGAAACGGCTCCCCTGACAGCGATGGCACCGCAGCGGGA
ATGCCCCGCGACATGCGTAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSNFLSYEQDGHVVTLTMSEPERRNPLTGNTAVPEFLAAIERIESDTSVRAVIITGSGTAFSSGGNIHEMKRQASGTASA
MDVRRDYRHGIQRLPLALFNLEVPVIAAVNGPALGAGLDLTCMCDIRIASRAAQFAESFVKLGIIPGDGGAWLLPRIIGM
SRAAELTFTGKAIDAQTALEWNLVSQVVEPEALLPTAREIAAAIAANPPHAVRLAKRLLREGMHTSLGTLLELSAVYQAV
SHQAADHKEAVEAFLDKRKPVFKG

Sequences:

>Translated_264_residues
MSNFLSYEQDGHVVTLTMSEPERRNPLTGNTAVPEFLAAIERIESDTSVRAVIITGSGTAFSSGGNIHEMKRQASGTASA
MDVRRDYRHGIQRLPLALFNLEVPVIAAVNGPALGAGLDLTCMCDIRIASRAAQFAESFVKLGIIPGDGGAWLLPRIIGM
SRAAELTFTGKAIDAQTALEWNLVSQVVEPEALLPTAREIAAAIAANPPHAVRLAKRLLREGMHTSLGTLLELSAVYQAV
SHQAADHKEAVEAFLDKRKPVFKG
>Mature_263_residues
SNFLSYEQDGHVVTLTMSEPERRNPLTGNTAVPEFLAAIERIESDTSVRAVIITGSGTAFSSGGNIHEMKRQASGTASAM
DVRRDYRHGIQRLPLALFNLEVPVIAAVNGPALGAGLDLTCMCDIRIASRAAQFAESFVKLGIIPGDGGAWLLPRIIGMS
RAAELTFTGKAIDAQTALEWNLVSQVVEPEALLPTAREIAAAIAANPPHAVRLAKRLLREGMHTSLGTLLELSAVYQAVS
HQAADHKEAVEAFLDKRKPVFKG

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=257, Percent_Identity=33.852140077821, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI4502327, Length=262, Percent_Identity=32.824427480916, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI31542718, Length=267, Percent_Identity=31.4606741573034, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI70995211, Length=262, Percent_Identity=30.1526717557252, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI213417737, Length=216, Percent_Identity=26.8518518518519, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI157694516, Length=216, Percent_Identity=26.8518518518519, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116235487, Length=205, Percent_Identity=25.8536585365854, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI45643119, Length=214, Percent_Identity=25.7009345794392, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI260275230, Length=214, Percent_Identity=25.7009345794392, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI260274832, Length=214, Percent_Identity=25.7009345794392, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI221136756, Length=228, Percent_Identity=25.4385964912281, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI221136753, Length=228, Percent_Identity=25.4385964912281, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI221307494, Length=228, Percent_Identity=25.4385964912281, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI150378541, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI157694520, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=37.593984962406, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=34.0909090909091, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI221142681, Length=269, Percent_Identity=32.7137546468402, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788597, Length=274, Percent_Identity=30.2919708029197, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082183, Length=221, Percent_Identity=30.316742081448, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788682, Length=250, Percent_Identity=29.6, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=30.9644670050761, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=32.1285140562249, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=32.5991189427313, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=29.1187739463602, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=272, Percent_Identity=27.2058823529412, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=188, Percent_Identity=29.2553191489362, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=234, Percent_Identity=29.0598290598291, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=189, Percent_Identity=30.1587301587302, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=189, Percent_Identity=30.1587301587302, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=220, Percent_Identity=25, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129971, Length=255, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24653477, Length=255, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=31.5175097276265, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24654903, Length=253, Percent_Identity=26.8774703557312, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357171, Length=238, Percent_Identity=27.3109243697479, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=24.4274809160305, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650670, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920382, Length=263, Percent_Identity=27.3764258555133, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28291; Mature: 28160

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFLSYEQDGHVVTLTMSEPERRNPLTGNTAVPEFLAAIERIESDTSVRAVIITGSGTA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FSSGGNIHEMKRQASGTASAMDVRRDYRHGIQRLPLALFNLEVPVIAAVNGPALGAGLDL
ECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEECCCCCCCCCCE
TCMCDIRIASRAAQFAESFVKLGIIPGDGGAWLLPRIIGMSRAAELTFTGKAIDAQTALE
EEEECHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCHHCEEEECCCCCCHHHHHH
WNLVSQVVEPEALLPTAREIAAAIAANPPHAVRLAKRLLREGMHTSLGTLLELSAVYQAV
HHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SHQAADHKEAVEAFLDKRKPVFKG
HHHCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNFLSYEQDGHVVTLTMSEPERRNPLTGNTAVPEFLAAIERIESDTSVRAVIITGSGTA
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FSSGGNIHEMKRQASGTASAMDVRRDYRHGIQRLPLALFNLEVPVIAAVNGPALGAGLDL
ECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEECCCCCCCCCCE
TCMCDIRIASRAAQFAESFVKLGIIPGDGGAWLLPRIIGMSRAAELTFTGKAIDAQTALE
EEEECHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCHHCEEEECCCCCCHHHHHH
WNLVSQVVEPEALLPTAREIAAAIAANPPHAVRLAKRLLREGMHTSLGTLLELSAVYQAV
HHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SHQAADHKEAVEAFLDKRKPVFKG
HHHCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]