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The map label for this gene is acdA [H]

Identifier: 94314060

GI number: 94314060

Start: 1839093

End: 1840331

Strand: Reverse

Name: acdA [H]

Synonym: Rmet_5141

Alternate gene names: 94314060

Gene position: 1840331-1839093 (Counterclockwise)

Preceding gene: 94314061

Following gene: 94314059

Centisome position: 71.33

GC content: 66.26

Gene sequence:

>1239_bases
ATGGATATCGACGAGTCTCCGCAAGACCTGCAGTTTCGCGCCGAGGTGCGCGCCTGGATCTCCGAAGCGTTTGATGACGA
GCTTCGCGCCATGATGGCGCAATCGAAGAACGGTTATCTCGACAAGGCGGCACAGGTACGCTGGCAAAAGGCCCTGCACG
CGCGTGGCTGGGCCGCGCCGAACTGGCCGCAAGCACATGGTGGCCCCGGCTGGACACCCACGCAACGGCACCTCTTCCAG
AGCGAACTGGCCGCCGCCGGTTGCCCGCCGGTGTCGCCGATGGGTCTCAAGATGGTGGCGCCCGTCATCATGAAGTACGG
CAGCCCCGAGCAACAGGCCCGCTTCCTGCCGCGCATCCTGGCGTCCGACGACTGGTGGTGCCAGGGCTACTCCGAACCGA
ACTCAGGCTCCGATCTGGCCTCGCTGCAGATGCGCGCGACACGCGGCGTCGATGCGAATGGCGAGCACTACATCCTCAAC
GGTTCGAAGATCTGGACGACGCACGCCCAGTGGGCCGACTGGATGTTCTGTCTGGTGCGGACCTCGCGCGAGGGCAGGCC
GCAGGAGGGCATTACGTTCCTGCTGCTCGACATGCGCACGCCGGGTATCACCGTATCGGCGCTGCCTACGCTCGACGGCC
CGATGGAGGGCCAGCAGGAGGTCAATCAGGTTTTCTTTGACGATGTGCGCGTGCCGGCCGCCCAACGCATTGGCGAGGAG
GGCATGGGCTGGACCATTGCCAAGTACCTGCTCGAGTTCGAGCGTGGCGGCAGCTTCGCGCCGATGCTGCACCGGCAACT
GGACAAGGTGGCTGCCATGGCCGCCGCTCAGCCCGGTGAGGATGGCACCGGGCGGCTGGTCGACGATCCCGTCTTCCGGC
AACGGCTGGGCGCCACGTATGTGCGCGTGGCGGCGACCGAGGCGGCGGAGTTGCGGCTGTTCTCCGGCGTGGCCTCGGGT
ACGTCGATCGGCGCGGCGTCGAGCATGATCAAGTTGGTCGGTACCGAGACGGCACAGGCCATCTCCGAGCTAGCCGTCGA
CGTGCTCGGACCCTATGCGCTGCCATTCGTGCGGGATACCTGGGCCGAGATCCAGGGCCGCGCTGCCGACCCGCGTCTGG
GTCCGGACGATGCCGCCCCGATTGCGCCGCGCTACTTCAACTATCGCAAGGCATCGATCTACGGCGGTTCGAGCGAGATC
CAGCGCAACATCATCGCGCGACAGGTATTGCGGCTCTGA

Upstream 100 bases:

>100_bases
TCAAGCGTGTCACCGCCATCGGCCTGCAGTTCGGCAACGTTGCCTACCATCTGCGCCGTTGTGTCGACCTGCGCTACCCG
GCCAACGCATAAGGACCGCC

Downstream 100 bases:

>100_bases
GTGCCCGCATTGGCGTCCCTCGACGCCATTTGTCACCAGTACCCATCCTATCAATCAAAAAGGGAGACAAGGCTCATGGA
GACGGAATACCTCGCGACGC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MDIDESPQDLQFRAEVRAWISEAFDDELRAMMAQSKNGYLDKAAQVRWQKALHARGWAAPNWPQAHGGPGWTPTQRHLFQ
SELAAAGCPPVSPMGLKMVAPVIMKYGSPEQQARFLPRILASDDWWCQGYSEPNSGSDLASLQMRATRGVDANGEHYILN
GSKIWTTHAQWADWMFCLVRTSREGRPQEGITFLLLDMRTPGITVSALPTLDGPMEGQQEVNQVFFDDVRVPAAQRIGEE
GMGWTIAKYLLEFERGGSFAPMLHRQLDKVAAMAAAQPGEDGTGRLVDDPVFRQRLGATYVRVAATEAAELRLFSGVASG
TSIGAASSMIKLVGTETAQAISELAVDVLGPYALPFVRDTWAEIQGRAADPRLGPDDAAPIAPRYFNYRKASIYGGSSEI
QRNIIARQVLRL

Sequences:

>Translated_412_residues
MDIDESPQDLQFRAEVRAWISEAFDDELRAMMAQSKNGYLDKAAQVRWQKALHARGWAAPNWPQAHGGPGWTPTQRHLFQ
SELAAAGCPPVSPMGLKMVAPVIMKYGSPEQQARFLPRILASDDWWCQGYSEPNSGSDLASLQMRATRGVDANGEHYILN
GSKIWTTHAQWADWMFCLVRTSREGRPQEGITFLLLDMRTPGITVSALPTLDGPMEGQQEVNQVFFDDVRVPAAQRIGEE
GMGWTIAKYLLEFERGGSFAPMLHRQLDKVAAMAAAQPGEDGTGRLVDDPVFRQRLGATYVRVAATEAAELRLFSGVASG
TSIGAASSMIKLVGTETAQAISELAVDVLGPYALPFVRDTWAEIQGRAADPRLGPDDAAPIAPRYFNYRKASIYGGSSEI
QRNIIARQVLRL
>Mature_412_residues
MDIDESPQDLQFRAEVRAWISEAFDDELRAMMAQSKNGYLDKAAQVRWQKALHARGWAAPNWPQAHGGPGWTPTQRHLFQ
SELAAAGCPPVSPMGLKMVAPVIMKYGSPEQQARFLPRILASDDWWCQGYSEPNSGSDLASLQMRATRGVDANGEHYILN
GSKIWTTHAQWADWMFCLVRTSREGRPQEGITFLLLDMRTPGITVSALPTLDGPMEGQQEVNQVFFDDVRVPAAQRIGEE
GMGWTIAKYLLEFERGGSFAPMLHRQLDKVAAMAAAQPGEDGTGRLVDDPVFRQRLGATYVRVAATEAAELRLFSGVASG
TSIGAASSMIKLVGTETAQAISELAVDVLGPYALPFVRDTWAEIQGRAADPRLGPDDAAPIAPRYFNYRKASIYGGSSEI
QRNIIARQVLRL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=404, Percent_Identity=27.970297029703, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI21361497, Length=373, Percent_Identity=26.0053619302949, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI226958414, Length=222, Percent_Identity=27.4774774774775, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI226958412, Length=209, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4501857, Length=425, Percent_Identity=24.2352941176471, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI7656849, Length=182, Percent_Identity=31.8681318681319, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557235, Length=379, Percent_Identity=23.7467018469657, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI76496475, Length=379, Percent_Identity=23.7467018469657, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4557231, Length=369, Percent_Identity=23.3062330623306, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4501859, Length=357, Percent_Identity=26.3305322128852, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI187960098, Length=369, Percent_Identity=23.3062330623306, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=418, Percent_Identity=22.9665071770335, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786223, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=436, Percent_Identity=25.9174311926606, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=26.9230769230769, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=390, Percent_Identity=25.3846153846154, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=388, Percent_Identity=24.4845360824742, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=199, Percent_Identity=31.1557788944724, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=210, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=199, Percent_Identity=31.1557788944724, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=27.2479564032698, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=203, Percent_Identity=31.5270935960591, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=277, Percent_Identity=23.826714801444, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=163, Percent_Identity=26.9938650306748, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=221, Percent_Identity=28.5067873303167, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281363737, Length=311, Percent_Identity=25.08038585209, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355753, Length=248, Percent_Identity=28.2258064516129, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24666513, Length=325, Percent_Identity=25.8461538461538, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=158, Percent_Identity=29.746835443038, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=24.7252747252747, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45306; Mature: 45306

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDESPQDLQFRAEVRAWISEAFDDELRAMMAQSKNGYLDKAAQVRWQKALHARGWAAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
NWPQAHGGPGWTPTQRHLFQSELAAAGCPPVSPMGLKMVAPVIMKYGSPEQQARFLPRIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
ASDDWWCQGYSEPNSGSDLASLQMRATRGVDANGEHYILNGSKIWTTHAQWADWMFCLVR
CCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHH
TSREGRPQEGITFLLLDMRTPGITVSALPTLDGPMEGQQEVNQVFFDDVRVPAAQRIGEE
HCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCC
GMGWTIAKYLLEFERGGSFAPMLHRQLDKVAAMAAAQPGEDGTGRLVDDPVFRQRLGATY
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCE
VRVAATEAAELRLFSGVASGTSIGAASSMIKLVGTETAQAISELAVDVLGPYALPFVRDT
EEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHH
WAEIQGRAADPRLGPDDAAPIAPRYFNYRKASIYGGSSEIQRNIIARQVLRL
HHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIDESPQDLQFRAEVRAWISEAFDDELRAMMAQSKNGYLDKAAQVRWQKALHARGWAAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
NWPQAHGGPGWTPTQRHLFQSELAAAGCPPVSPMGLKMVAPVIMKYGSPEQQARFLPRIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
ASDDWWCQGYSEPNSGSDLASLQMRATRGVDANGEHYILNGSKIWTTHAQWADWMFCLVR
CCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHH
TSREGRPQEGITFLLLDMRTPGITVSALPTLDGPMEGQQEVNQVFFDDVRVPAAQRIGEE
HCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCC
GMGWTIAKYLLEFERGGSFAPMLHRQLDKVAAMAAAQPGEDGTGRLVDDPVFRQRLGATY
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCE
VRVAATEAAELRLFSGVASGTSIGAASSMIKLVGTETAQAISELAVDVLGPYALPFVRDT
EEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHH
WAEIQGRAADPRLGPDDAAPIAPRYFNYRKASIYGGSSEIQRNIIARQVLRL
HHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]