| Definition | Cupriavidus metallidurans CH34 megaplasmid, complete sequence. |
|---|---|
| Accession | NC_007974 |
| Length | 2,580,084 |
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The map label for this gene is phaB3 [H]
Identifier: 94314042
GI number: 94314042
Start: 1818056
End: 1818802
Strand: Reverse
Name: phaB3 [H]
Synonym: Rmet_5123
Alternate gene names: 94314042
Gene position: 1818802-1818056 (Counterclockwise)
Preceding gene: 94314043
Following gene: 94314041
Centisome position: 70.49
GC content: 61.58
Gene sequence:
>747_bases ATGAGCTCCGGACGCATTGCGGTAGTGACGGGGGGCATGGGTGGTCTGGGCGAAGCCATCGCCGAAAGGCTGCTGAGCGA CGGATTCCGCGTGGTCGTCACGCATTCGCTTGGCAACGATCATGTCGCGACCTGGCTGCGCGAGCACAGTACGCAGCAAC GCGAGTTCGTGGCCTACCCGGTAGATGTCGCCGACTTCGAATCCTGCCAGCAATGTGCGGCCAGGATATTGTCCGAGGTG GGCCCGGTGGATGTCCTGATCAACAATGCCGGCATCACGCGCGATTCGACCTTGCGCAAGATGACGCACGAGGCCTGGCG CGCCGTGATGTCTACCGACCTCGATTCGGTGTTCAACATGACCAAGCCGTTCTGCGAAGGCATGGTGGAGCGTCGCTGGG GCCGGATCGTGAACATCTCATCGATCAACGGCTCGAAGGGCGCGTTTGGCCAGACTAACTATGCAGCGGCAAAGGCCGGC ATCCACGGATTCAGCAAATCGCTGGCGCTGGAGCTGGCCAGCAAGGGCGTGACGGTCAACACCGTTTCTCCCGGTTATCT CGATACGAAGATGGTGCGGGCAGTGCCGCAGGACGTGCTCGACCAGCACGTGATTCCGCAGATTCCGGTCGGCCGCCTGG GTCAGCCGAAGGAAGTGGCCGCGCTGATCAGTTACCTCTGCTCGGACGATGGCGCGTACGTGACCGGCGCCAACCTTGCC ATCAATGGTGGCCAACATATGGATTGA
Upstream 100 bases:
>100_bases TCGGAAAGATGACGCCGTTTGGGGTGGTACCGCCCAGCGAGTCCAGCACGACTGCGACCAGCGCCACCCGTTCGCGCGCC GCCAAGGGCGGTGCGACATC
Downstream 100 bases:
>100_bases TGCATGCGCCCCAAAAAGCCAGTCGCCCTCGAGCACACCACGGATACGCTGATCGAACAGGCCCCGCCCGCCAAACGGGC GAAGGCCACCTCACCCAAGC
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 247
Protein sequence:
>248_residues MSSGRIAVVTGGMGGLGEAIAERLLSDGFRVVVTHSLGNDHVATWLREHSTQQREFVAYPVDVADFESCQQCAARILSEV GPVDVLINNAGITRDSTLRKMTHEAWRAVMSTDLDSVFNMTKPFCEGMVERRWGRIVNISSINGSKGAFGQTNYAAAKAG IHGFSKSLALELASKGVTVNTVSPGYLDTKMVRAVPQDVLDQHVIPQIPVGRLGQPKEVAALISYLCSDDGAYVTGANLA INGGQHMD
Sequences:
>Translated_248_residues MSSGRIAVVTGGMGGLGEAIAERLLSDGFRVVVTHSLGNDHVATWLREHSTQQREFVAYPVDVADFESCQQCAARILSEV GPVDVLINNAGITRDSTLRKMTHEAWRAVMSTDLDSVFNMTKPFCEGMVERRWGRIVNISSINGSKGAFGQTNYAAAKAG IHGFSKSLALELASKGVTVNTVSPGYLDTKMVRAVPQDVLDQHVIPQIPVGRLGQPKEVAALISYLCSDDGAYVTGANLA INGGQHMD >Mature_247_residues SSGRIAVVTGGMGGLGEAIAERLLSDGFRVVVTHSLGNDHVATWLREHSTQQREFVAYPVDVADFESCQQCAARILSEVG PVDVLINNAGITRDSTLRKMTHEAWRAVMSTDLDSVFNMTKPFCEGMVERRWGRIVNISSINGSKGAFGQTNYAAAKAGI HGFSKSLALELASKGVTVNTVSPGYLDTKMVRAVPQDVLDQHVIPQIPVGRLGQPKEVAALISYLCSDDGAYVTGANLAI NGGQHMD
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=33.852140077821, Blast_Score=141, Evalue=6e-34, Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=31.8897637795276, Blast_Score=127, Evalue=9e-30, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=28.6885245901639, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=28.740157480315, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI4504505, Length=241, Percent_Identity=30.7053941908714, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.9595141700405, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI66933014, Length=220, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=30.327868852459, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=30.5019305019305, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.0983606557377, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI4503301, Length=193, Percent_Identity=29.0155440414508, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=26.2948207171315, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=32.5, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=28.921568627451, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.0833333333333, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=31.9587628865979, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=28.957528957529, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=27.4611398963731, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI226371731, Length=203, Percent_Identity=29.064039408867, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7705855, Length=216, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI25282469, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI109715829, Length=231, Percent_Identity=25.974025974026, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=29.4797687861272, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI19743808, Length=190, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=43.0894308943089, Blast_Score=205, Evalue=2e-54, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.2834645669291, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=27.1604938271605, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=29.045643153527, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=28.9795918367347, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=30.3149606299213, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=33.6032388663968, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=27.4590163934426, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.3172690763052, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.8449612403101, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=27.1604938271605, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=30, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787526, Length=247, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=43.0894308943089, Blast_Score=180, Evalue=6e-46, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=40.3225806451613, Blast_Score=166, Evalue=8e-42, Organism=Caenorhabditis elegans, GI17568967, Length=235, Percent_Identity=33.6170212765957, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=28.2868525896414, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=35.0253807106599, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=29.2682926829268, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=34.6938775510204, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.4176245210728, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=28.6290322580645, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.8, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.8973384030418, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=26.7175572519084, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=28.4090909090909, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=26.7441860465116, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.027027027027, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=29.4776119402985, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=25.8687258687259, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=26.2548262548263, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.030303030303, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=26.0536398467433, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=25.4752851711027, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=25.5230125523013, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=26.4367816091954, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=26.2357414448669, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.171875, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=25.9927797833935, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=25.968992248062, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=25.5725190839695, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=26.4248704663212, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=25.9398496240602, Blast_Score=71, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=239, Percent_Identity=31.7991631799163, Blast_Score=108, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=27.0916334661355, Blast_Score=94, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6320089, Length=215, Percent_Identity=26.046511627907, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=36.9918699186992, Blast_Score=152, Evalue=2e-37, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=32.6693227091633, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32.4, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=35.2331606217617, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI18859837, Length=247, Percent_Identity=33.6032388663968, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=28.2786885245902, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=34.2105263157895, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=28.7449392712551, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=35.3260869565217, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=28.643216080402, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=28.7878787878788, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24581726, Length=156, Percent_Identity=32.0512820512821, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=31.9767441860465, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=29.6875, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=30.6532663316583, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=30.2127659574468, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=28.5, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=28.5, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=27.7227722772277, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=27.7227722772277, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26576; Mature: 26444
Theoretical pI: Translated: 6.62; Mature: 6.62
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSGRIAVVTGGMGGLGEAIAERLLSDGFRVVVTHSLGNDHVATWLREHSTQQREFVAYP CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHEEEEC VDVADFESCQQCAARILSEVGPVDVLINNAGITRDSTLRKMTHEAWRAVMSTDLDSVFNM CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH TKPFCEGMVERRWGRIVNISSINGSKGAFGQTNYAAAKAGIHGFSKSLALELASKGVTVN HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE TVSPGYLDTKMVRAVPQDVLDQHVIPQIPVGRLGQPKEVAALISYLCSDDGAYVTGANLA ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEE INGGQHMD ECCCCCCC >Mature Secondary Structure SSGRIAVVTGGMGGLGEAIAERLLSDGFRVVVTHSLGNDHVATWLREHSTQQREFVAYP CCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHEEEEC VDVADFESCQQCAARILSEVGPVDVLINNAGITRDSTLRKMTHEAWRAVMSTDLDSVFNM CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH TKPFCEGMVERRWGRIVNISSINGSKGAFGQTNYAAAKAGIHGFSKSLALELASKGVTVN HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE TVSPGYLDTKMVRAVPQDVLDQHVIPQIPVGRLGQPKEVAALISYLCSDDGAYVTGANLA ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEE INGGQHMD ECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]