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The map label for this gene is cph2 [H]

Identifier: 94313963

GI number: 94313963

Start: 1727941

End: 1729143

Strand: Reverse

Name: cph2 [H]

Synonym: Rmet_5041

Alternate gene names: 94313963

Gene position: 1729143-1727941 (Counterclockwise)

Preceding gene: 94313964

Following gene: 94313961

Centisome position: 67.02

GC content: 63.51

Gene sequence:

>1203_bases
ATGTCCGAAGCAGACGTCGAAATGAGTTTCGTTGTTGATCCGGTTCGGGTCGAGTTCTCGGATCCGGGGCTCGAGCGGGA
GTTTCAGCAACACCATCTGCGGACCACGCGGGCGTCGTTGCGGGTCACCCTGGTGTTCTGTTCGCTGTTTTATCTGGCCT
TTTCCCTGACCGATCTGGCCGCGCTGGGCTATGGGACGTCGTTCCTCGTGCTGCTGCTGGGGCGAATCACCGTTGCGCTG
ACTGCCTGCGGCGGTCTGTATCTGATTCGCCGGAAAACTGAGTCGGTGCTGGCCCACCGGGCCGTGGCCAGCGCGGCGGA
GGTCGTCGGGATGGCGATCTTCATGCTGGTCGTCTGGTTCCGTCCCGGCGAGTTGCCCTGGCACGCGATGTCGCTCTGCA
TCATGCTGATCGTCATCTACGTCTTCATCCCAAATCGGCTCATCACCGCGATTGGCATCGCCCTTGGCGCGACGGCGGCC
TTCATCGCGCTGGCCGTGATAAGGGGGGAGTCGAGGTTCTCCGACGAAGTCACGATGGCGATGCTTCTGCTGCTGACCAA
CAGCTTCGGCATCATCGCGGCGCGCCGCTATCACCGGCTGTGGCGCGACGAGTATCGGGCGCTCAGTACATTGAAGGCGC
TATCCATCCGCGACCATCTCACAGCCTGCTTCAACCGGCGGCATCTGCACACGACGCTGCTGCCGCAGGTGCTGGAGCGG
GCTCGCGCCGAGCGTCGCTGGCTGACGCTGATGGTTTGCGATATCGACCATTTCAAGCGCGTCAACGACAACCACGGCCA
CCAGGGTGGCGATGCCGTGCTGATGCACGTTGCCATGCTGCTGCAGGACCGCATCCACGAGCCACGGGACAGCGTCGTTC
GCTACGGCGGGGAGGAGTTCCTGCTCGTCATGCCGCAGATGGACTTCGAGTCGGCCGCCAGTCTGGCCGAGGACATGCGC
GCCGCGGTGGCGGGCAGTGAGGTGCCCGGCCCCGATGGCAAGAGCATGCGCGCCACGGTCAGCATCGGGGTGCTCTCCGT
CGATTTCTCGGCCAGCGATACCGAGGTCACCGAAAGCGCGTTGATTGCCGCTGCCGATATGTTGCTCTATGAAGCCAAAC
GGGCCGGACGGAACAGCATCCGGACCCGGCTTTGGGCGGATATGGTGTCCAGCCACGCTGTCTTGAGTATGCGAACGGCC
TGA

Upstream 100 bases:

>100_bases
GCAGATCAAGGATTGAGGATTCTTTCCGGCTGCCAGGCTGTAATAGGAGACAATGGCGCACATTCAATGACCGCCGGGCC
GACTGGTCACCCACGCGCTT

Downstream 100 bases:

>100_bases
TTGACCGCCGGATGTATGGGCCACCGGCGAGGCCCGCATCAATCCGCATCAATCCGCATCAATCCGCATCAATCGGCTTC
AGTCCGCTTCACCCTCCAGA

Product: putative signaling protein (GGDEF domain)

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSEADVEMSFVVDPVRVEFSDPGLEREFQQHHLRTTRASLRVTLVFCSLFYLAFSLTDLAALGYGTSFLVLLLGRITVAL
TACGGLYLIRRKTESVLAHRAVASAAEVVGMAIFMLVVWFRPGELPWHAMSLCIMLIVIYVFIPNRLITAIGIALGATAA
FIALAVIRGESRFSDEVTMAMLLLLTNSFGIIAARRYHRLWRDEYRALSTLKALSIRDHLTACFNRRHLHTTLLPQVLER
ARAERRWLTLMVCDIDHFKRVNDNHGHQGGDAVLMHVAMLLQDRIHEPRDSVVRYGGEEFLLVMPQMDFESAASLAEDMR
AAVAGSEVPGPDGKSMRATVSIGVLSVDFSASDTEVTESALIAAADMLLYEAKRAGRNSIRTRLWADMVSSHAVLSMRTA

Sequences:

>Translated_400_residues
MSEADVEMSFVVDPVRVEFSDPGLEREFQQHHLRTTRASLRVTLVFCSLFYLAFSLTDLAALGYGTSFLVLLLGRITVAL
TACGGLYLIRRKTESVLAHRAVASAAEVVGMAIFMLVVWFRPGELPWHAMSLCIMLIVIYVFIPNRLITAIGIALGATAA
FIALAVIRGESRFSDEVTMAMLLLLTNSFGIIAARRYHRLWRDEYRALSTLKALSIRDHLTACFNRRHLHTTLLPQVLER
ARAERRWLTLMVCDIDHFKRVNDNHGHQGGDAVLMHVAMLLQDRIHEPRDSVVRYGGEEFLLVMPQMDFESAASLAEDMR
AAVAGSEVPGPDGKSMRATVSIGVLSVDFSASDTEVTESALIAAADMLLYEAKRAGRNSIRTRLWADMVSSHAVLSMRTA
>Mature_399_residues
SEADVEMSFVVDPVRVEFSDPGLEREFQQHHLRTTRASLRVTLVFCSLFYLAFSLTDLAALGYGTSFLVLLLGRITVALT
ACGGLYLIRRKTESVLAHRAVASAAEVVGMAIFMLVVWFRPGELPWHAMSLCIMLIVIYVFIPNRLITAIGIALGATAAF
IALAVIRGESRFSDEVTMAMLLLLTNSFGIIAARRYHRLWRDEYRALSTLKALSIRDHLTACFNRRHLHTTLLPQVLERA
RAERRWLTLMVCDIDHFKRVNDNHGHQGGDAVLMHVAMLLQDRIHEPRDSVVRYGGEEFLLVMPQMDFESAASLAEDMRA
AVAGSEVPGPDGKSMRATVSIGVLSVDFSASDTEVTESALIAAADMLLYEAKRAGRNSIRTRLWADMVSSHAVLSMRTA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=35, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=34.8837209302326, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082007, Length=204, Percent_Identity=30.3921568627451, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787802, Length=184, Percent_Identity=33.695652173913, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=34.0782122905028, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788085, Length=181, Percent_Identity=30.939226519337, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=34.5238095238095, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788381, Length=131, Percent_Identity=32.0610687022901, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 44452; Mature: 44321

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEADVEMSFVVDPVRVEFSDPGLEREFQQHHLRTTRASLRVTLVFCSLFYLAFSLTDLA
CCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGYGTSFLVLLLGRITVALTACGGLYLIRRKTESVLAHRAVASAAEVVGMAIFMLVVWF
HHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPGELPWHAMSLCIMLIVIYVFIPNRLITAIGIALGATAAFIALAVIRGESRFSDEVTMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MLLLLTNSFGIIAARRYHRLWRDEYRALSTLKALSIRDHLTACFNRRHLHTTLLPQVLER
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARAERRWLTLMVCDIDHFKRVNDNHGHQGGDAVLMHVAMLLQDRIHEPRDSVVRYGGEEF
HHHHHHEEEEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEE
LLVMPQMDFESAASLAEDMRAAVAGSEVPGPDGKSMRATVSIGVLSVDFSASDTEVTESA
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHH
LIAAADMLLYEAKRAGRNSIRTRLWADMVSSHAVLSMRTA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECC
>Mature Secondary Structure 
SEADVEMSFVVDPVRVEFSDPGLEREFQQHHLRTTRASLRVTLVFCSLFYLAFSLTDLA
CCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGYGTSFLVLLLGRITVALTACGGLYLIRRKTESVLAHRAVASAAEVVGMAIFMLVVWF
HHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPGELPWHAMSLCIMLIVIYVFIPNRLITAIGIALGATAAFIALAVIRGESRFSDEVTMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MLLLLTNSFGIIAARRYHRLWRDEYRALSTLKALSIRDHLTACFNRRHLHTTLLPQVLER
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ARAERRWLTLMVCDIDHFKRVNDNHGHQGGDAVLMHVAMLLQDRIHEPRDSVVRYGGEEF
HHHHHHEEEEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEE
LLVMPQMDFESAASLAEDMRAAVAGSEVPGPDGKSMRATVSIGVLSVDFSASDTEVTESA
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHH
LIAAADMLLYEAKRAGRNSIRTRLWADMVSSHAVLSMRTA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]