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The map label for this gene is pepV [H]

Identifier: 94313812

GI number: 94313812

Start: 1552500

End: 1554239

Strand: Direct

Name: pepV [H]

Synonym: Rmet_4890

Alternate gene names: 94313812

Gene position: 1552500-1554239 (Clockwise)

Preceding gene: 94313807

Following gene: 291481545

Centisome position: 60.17

GC content: 65.11

Gene sequence:

>1740_bases
ATGAATCGTCTGACTGCACGACTGCCAGCAGCAACCCTGCTGGCCGCCGCCCTGCTCGCCTGCCCGCTGACACCCATGGC
GAACGCGGCGACCATCGCCAAGCCGGAGCTCGACCAACTCGTGGCCGGTGCTACGACAACGCCACCAGCCAGTTTCAATG
CCTTCCTCGACGCCGCGGTCAAGGCCGACCCGAAACTTGCGCCTTCGGTGCGAGCCTATCGGGCAAAGCGCCCGCTCACG
GGCGACGACCTCGTCAACATCGGACGCCTGCTCGGTGTCTACAACCGCGTGCATAACGGGCATGCCGTGCTCGACAGCAT
CAGCGAGATGGTGGCGCTGCGCACGGTGCGCGACGACAAGGTGCCGCAGCACGAGAACCCCGCAATCATCGAGTTCGGCA
AGCTCGTGGAGCGGATGGCCAAGGACTTCGGCCTGCACTATCGCAACATCGACAACCGCGTGTTCGAAGTCACGCTGCCT
GGCACCGGCAAGGACACCTTCGGCATCCTTACCCATGCCGACGTGGTGCCCGTGGTGGCCGACGAATGGGTACTCGACGA
TGGCACGAAGCTCGACCCGTTCAAGGTCACGCGCGTAGGCGACTACCTCTATGGACGTGGCACGATCGACGACAAGGGCT
CGATTGCCGCCGCCCTCTACGCGATGAAAACCGTGCGCGAAAGCGGCGTGCCGCTGGCGCGTTCGATCCGGCTGATGATC
GAGACCACCGAGGAAACCGGTGGCGACGGCATGAAGTACTACCGCGAGAAAACCGCCCTGCCCGAGTACAACATCGTGCT
CGACAGCAAGTACCCCGCCGTGGTCGCCGAGAAAGGCTCGGGCGCGCTGACCGCGCGCTTCGCGGATCAGGCGGTGGACG
GCAAGCAGCCGGCCATCGTGGCCATGAGCGGCGCCGCCTCGGCCAACGCGATTCCTCAGACGGCGACGGCACGCATCAGC
GGCGGTGACCTGGCAGCCGTGGCCGCCGGCCTGGAAAAGGCGCGCGCCGGTTTCATCGCCCAGCATGAGGCCCAGGGCAA
GTTCTCGATCGACATCGCGCGTGACGGCGACGTCATCGTCGTGAAGGTGACTGGCACGTCCGCCCATGGCTCCCGCCCCG
AGGAAGGCGTGAACCCCGTGCCGCGTCTCGCGATGTTCCTGCAGTCGTCGGGCGTCGCCTTTGCAGACAACCAGTACGCC
CATGCGATCCGCTACCTGACCGACCTCTATGGCACCGACTATCTCGGGGAAAAGCTCGGCGTGGCCTATCGCGATGACTT
CATGGGTCCGTTGACGATCTCGCCGACGCTGATCCGCGAGCGCGGCGGCAAGCTCGAAGTCACCGCCAACGTGCGGATGC
CGCGCGGTGCAACGCCCGATGCCTTGCGCGCGAAGATCGCCGAGCGCATCCAGGGCTGGGCAGCAACCACGCACACCGCG
CTGGAAATCCAGCACGAACAGGGCGACTGGATGGCCCGGGACCCCAAGGGCGCCTGGCTAACCACATTGCTGAACATCTA
CGGTGATACCACCGGGCTCGAAGCCAAGCCCGTGCCGACCGCCGGCAGCACCACGGCCAAGCTGATGCCGAACGCGATCA
ACTTCGGGCCAGCGATGCCGGGCAAGAAGTACACCGCGCACAACGCGAAGGAGTACAAGGAAGTGCCGGACCTGAACCTG
GACATGCAGATGTTCACGGAGATGCTCGTGCGCGTTGGCAATCTGAAATCGATGCAGTAA

Upstream 100 bases:

>100_bases
TCTATCGACGAGTGATCTCCCTGCTTTCTTGCCGCACCGGGCGCCGCTATCATTCGGCCACCCAACAAAGACAACCAAGA
CAACCGAAGGGACAAACCCG

Downstream 100 bases:

>100_bases
GAGGCCGTTTCAAACTGAAGCGAAGCGGTTCTGGCTAGGGTGAAGCAGGGGTTTCGGCTCGCATGCGAGCCGCCTGCGGA
ACGGCATGTGCCTGCGAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MNRLTARLPAATLLAAALLACPLTPMANAATIAKPELDQLVAGATTTPPASFNAFLDAAVKADPKLAPSVRAYRAKRPLT
GDDLVNIGRLLGVYNRVHNGHAVLDSISEMVALRTVRDDKVPQHENPAIIEFGKLVERMAKDFGLHYRNIDNRVFEVTLP
GTGKDTFGILTHADVVPVVADEWVLDDGTKLDPFKVTRVGDYLYGRGTIDDKGSIAAALYAMKTVRESGVPLARSIRLMI
ETTEETGGDGMKYYREKTALPEYNIVLDSKYPAVVAEKGSGALTARFADQAVDGKQPAIVAMSGAASANAIPQTATARIS
GGDLAAVAAGLEKARAGFIAQHEAQGKFSIDIARDGDVIVVKVTGTSAHGSRPEEGVNPVPRLAMFLQSSGVAFADNQYA
HAIRYLTDLYGTDYLGEKLGVAYRDDFMGPLTISPTLIRERGGKLEVTANVRMPRGATPDALRAKIAERIQGWAATTHTA
LEIQHEQGDWMARDPKGAWLTTLLNIYGDTTGLEAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNAKEYKEVPDLNL
DMQMFTEMLVRVGNLKSMQ

Sequences:

>Translated_579_residues
MNRLTARLPAATLLAAALLACPLTPMANAATIAKPELDQLVAGATTTPPASFNAFLDAAVKADPKLAPSVRAYRAKRPLT
GDDLVNIGRLLGVYNRVHNGHAVLDSISEMVALRTVRDDKVPQHENPAIIEFGKLVERMAKDFGLHYRNIDNRVFEVTLP
GTGKDTFGILTHADVVPVVADEWVLDDGTKLDPFKVTRVGDYLYGRGTIDDKGSIAAALYAMKTVRESGVPLARSIRLMI
ETTEETGGDGMKYYREKTALPEYNIVLDSKYPAVVAEKGSGALTARFADQAVDGKQPAIVAMSGAASANAIPQTATARIS
GGDLAAVAAGLEKARAGFIAQHEAQGKFSIDIARDGDVIVVKVTGTSAHGSRPEEGVNPVPRLAMFLQSSGVAFADNQYA
HAIRYLTDLYGTDYLGEKLGVAYRDDFMGPLTISPTLIRERGGKLEVTANVRMPRGATPDALRAKIAERIQGWAATTHTA
LEIQHEQGDWMARDPKGAWLTTLLNIYGDTTGLEAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNAKEYKEVPDLNL
DMQMFTEMLVRVGNLKSMQ
>Mature_579_residues
MNRLTARLPAATLLAAALLACPLTPMANAATIAKPELDQLVAGATTTPPASFNAFLDAAVKADPKLAPSVRAYRAKRPLT
GDDLVNIGRLLGVYNRVHNGHAVLDSISEMVALRTVRDDKVPQHENPAIIEFGKLVERMAKDFGLHYRNIDNRVFEVTLP
GTGKDTFGILTHADVVPVVADEWVLDDGTKLDPFKVTRVGDYLYGRGTIDDKGSIAAALYAMKTVRESGVPLARSIRLMI
ETTEETGGDGMKYYREKTALPEYNIVLDSKYPAVVAEKGSGALTARFADQAVDGKQPAIVAMSGAASANAIPQTATARIS
GGDLAAVAAGLEKARAGFIAQHEAQGKFSIDIARDGDVIVVKVTGTSAHGSRPEEGVNPVPRLAMFLQSSGVAFADNQYA
HAIRYLTDLYGTDYLGEKLGVAYRDDFMGPLTISPTLIRERGGKLEVTANVRMPRGATPDALRAKIAERIQGWAATTHTA
LEIQHEQGDWMARDPKGAWLTTLLNIYGDTTGLEAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNAKEYKEVPDLNL
DMQMFTEMLVRVGNLKSMQ

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 62210; Mature: 62210

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLTARLPAATLLAAALLACPLTPMANAATIAKPELDQLVAGATTTPPASFNAFLDAAV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
KADPKLAPSVRAYRAKRPLTGDDLVNIGRLLGVYNRVHNGHAVLDSISEMVALRTVRDDK
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VPQHENPAIIEFGKLVERMAKDFGLHYRNIDNRVFEVTLPGTGKDTFGILTHADVVPVVA
CCCCCCCCEEHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEEE
DEWVLDDGTKLDPFKVTRVGDYLYGRGTIDDKGSIAAALYAMKTVRESGVPLARSIRLMI
CCEEECCCCCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEE
ETTEETGGDGMKYYREKTALPEYNIVLDSKYPAVVAEKGSGALTARFADQAVDGKQPAIV
EECCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCEEEEEHHHHHCCCCCCEEE
AMSGAASANAIPQTATARISGGDLAAVAAGLEKARAGFIAQHEAQGKFSIDIARDGDVIV
EECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCEEE
VKVTGTSAHGSRPEEGVNPVPRLAMFLQSSGVAFADNQYAHAIRYLTDLYGTDYLGEKLG
EEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCHHHHHHC
VAYRDDFMGPLTISPTLIRERGGKLEVTANVRMPRGATPDALRAKIAERIQGWAATTHTA
CEEHHCCCCCEECCHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCHHCCCEEE
LEIQHEQGDWMARDPKGAWLTTLLNIYGDTTGLEAKPVPTAGSTTAKLMPNAINFGPAMP
EEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
GKKYTAHNAKEYKEVPDLNLDMQMFTEMLVRVGNLKSMQ
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRLTARLPAATLLAAALLACPLTPMANAATIAKPELDQLVAGATTTPPASFNAFLDAAV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
KADPKLAPSVRAYRAKRPLTGDDLVNIGRLLGVYNRVHNGHAVLDSISEMVALRTVRDDK
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VPQHENPAIIEFGKLVERMAKDFGLHYRNIDNRVFEVTLPGTGKDTFGILTHADVVPVVA
CCCCCCCCEEHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEEE
DEWVLDDGTKLDPFKVTRVGDYLYGRGTIDDKGSIAAALYAMKTVRESGVPLARSIRLMI
CCEEECCCCCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEE
ETTEETGGDGMKYYREKTALPEYNIVLDSKYPAVVAEKGSGALTARFADQAVDGKQPAIV
EECCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCEEEEEHHHHHCCCCCCEEE
AMSGAASANAIPQTATARISGGDLAAVAAGLEKARAGFIAQHEAQGKFSIDIARDGDVIV
EECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCEEE
VKVTGTSAHGSRPEEGVNPVPRLAMFLQSSGVAFADNQYAHAIRYLTDLYGTDYLGEKLG
EEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCHHHHHHC
VAYRDDFMGPLTISPTLIRERGGKLEVTANVRMPRGATPDALRAKIAERIQGWAATTHTA
CEEHHCCCCCEECCHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCHHCCCEEE
LEIQHEQGDWMARDPKGAWLTTLLNIYGDTTGLEAKPVPTAGSTTAKLMPNAINFGPAMP
EEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
GKKYTAHNAKEYKEVPDLNLDMQMFTEMLVRVGNLKSMQ
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]