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The map label for this gene is catM [H]

Identifier: 94313801

GI number: 94313801

Start: 1541086

End: 1541961

Strand: Direct

Name: catM [H]

Synonym: Rmet_4879

Alternate gene names: 94313801

Gene position: 1541086-1541961 (Clockwise)

Preceding gene: 94313796

Following gene: 94313803

Centisome position: 59.73

GC content: 66.1

Gene sequence:

>876_bases
ATGGAACTCCGCCACCTCCGCTACTTCCAGACGGTTGCCCAGGAACTCAACGTGACACGGGCGGCCGAAAAGCTTCATAT
GGCACAGCCGCCACTTTCCCGGCAAATCCGCCAGTTCGAGGAAGAAGTCGGCGTGGCGTTGTTCGATCGTGTCGGGCGGG
GCCTGAGGTTGACCGAGGCGGGCCGTTTCCTGCTCGAGCAGTCGCTGCAACTGACCCAGCGACTGGAGGAGACGCTGGAA
AGCACGCGGCGCATCGGCCGCAATGAAAAGCGCTGGTTCGGCATCGGCTTCGTGCCGTCGGTGCTGTATGGCGTGCTGCC
CGAGCTGATCCGCGAACTGCGTGGCGACGATAGCCAGGTGGAGGTCGGCCTGACCGAGATGATCACGGTGCAGCAACTCG
AAGCGCTCAAGTCCGGGCGGATCGATCTGGCCTTCGGGCGTCTCACGTTCAACGACCCGGCGATCGTCCAGCAGGTGGTG
ATGGCCGAATCGCTGGTGGCGGCGATCCCGGGCACCGCGCCCACCCCCACCGCTCCTTTCGATGCCGACGCGCTGGCCCG
ACAGCCGCTGATCCTCTATCCGGCCCGGCCACGGCCAAGCTACGCCGACCATGTGCTGTCGCTGTTCCGCGGCCAAGGGT
TGCAGCCCCGCGTGGTGCAGGAGGCCAACGAACTGCAGACCGCGCTCGGCCTCGTCGCCGCCGGGCTAGGCATCACGCTC
GTGCCGTCCTCGGTGCAGCGCCTGCATCGTGATGATGTGCGCTATGTGCCGATCAACGCTCCGGGCTTCGTCTCACCCGT
GATCATGAGCTACCGCTCTGGCGACACCTCGCCATACCTGGCCCGCGCGGTCGCATGGGTCCTGCAGCAAGCGTAG

Upstream 100 bases:

>100_bases
AAGACCGAAGATGTCTCATCTCATACCTTTTCGGTATGCCAGGATTCTCCTCCTCTCCCTGCTGCGGGAGAGGGAAAAAC
CCACCGCGATCGCCATCACC

Downstream 100 bases:

>100_bases
TCACTCCTGGGCCGGCGGAATGTACTCCATGCCGATTTCCTCGTAGAGCCGGTAGATCATGTCCAGCATCGCACGCAGGT
CCTCGGATTCGTCCAGTGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: CatBC operon transcriptional activator [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MELRHLRYFQTVAQELNVTRAAEKLHMAQPPLSRQIRQFEEEVGVALFDRVGRGLRLTEAGRFLLEQSLQLTQRLEETLE
STRRIGRNEKRWFGIGFVPSVLYGVLPELIRELRGDDSQVEVGLTEMITVQQLEALKSGRIDLAFGRLTFNDPAIVQQVV
MAESLVAAIPGTAPTPTAPFDADALARQPLILYPARPRPSYADHVLSLFRGQGLQPRVVQEANELQTALGLVAAGLGITL
VPSSVQRLHRDDVRYVPINAPGFVSPVIMSYRSGDTSPYLARAVAWVLQQA

Sequences:

>Translated_291_residues
MELRHLRYFQTVAQELNVTRAAEKLHMAQPPLSRQIRQFEEEVGVALFDRVGRGLRLTEAGRFLLEQSLQLTQRLEETLE
STRRIGRNEKRWFGIGFVPSVLYGVLPELIRELRGDDSQVEVGLTEMITVQQLEALKSGRIDLAFGRLTFNDPAIVQQVV
MAESLVAAIPGTAPTPTAPFDADALARQPLILYPARPRPSYADHVLSLFRGQGLQPRVVQEANELQTALGLVAAGLGITL
VPSSVQRLHRDDVRYVPINAPGFVSPVIMSYRSGDTSPYLARAVAWVLQQA
>Mature_291_residues
MELRHLRYFQTVAQELNVTRAAEKLHMAQPPLSRQIRQFEEEVGVALFDRVGRGLRLTEAGRFLLEQSLQLTQRLEETLE
STRRIGRNEKRWFGIGFVPSVLYGVLPELIRELRGDDSQVEVGLTEMITVQQLEALKSGRIDLAFGRLTFNDPAIVQQVV
MAESLVAAIPGTAPTPTAPFDADALARQPLILYPARPRPSYADHVLSLFRGQGLQPRVVQEANELQTALGLVAAGLGITL
VPSSVQRLHRDDVRYVPINAPGFVSPVIMSYRSGDTSPYLARAVAWVLQQA

Specific function: Positive regulator of the catBC operon that degrades catechol to acetyl-CoA. CatR binds in trans to the catR-catBC promoter-control region in the presence or absence of inducer but only activates the catBC operon in the presence of the inducer, cis-cis-mu

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=281, Percent_Identity=33.0960854092527, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=35.1351351351351, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=28.7671232876712, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790399, Length=287, Percent_Identity=29.616724738676, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787806, Length=246, Percent_Identity=28.8617886178862, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=25.8196721311475, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081904, Length=219, Percent_Identity=26.027397260274, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=27.8225806451613, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787949, Length=301, Percent_Identity=24.2524916943522, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=25.4980079681275, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=25.5905511811024, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789506, Length=243, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788296, Length=250, Percent_Identity=27.6, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32358; Mature: 32358

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFQTVAQELNVTRAAEKLHMAQPPLSRQIRQFEEEVGVALFDRVGRGLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
GRFLLEQSLQLTQRLEETLESTRRIGRNEKRWFGIGFVPSVLYGVLPELIRELRGDDSQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEE
EVGLTEMITVQQLEALKSGRIDLAFGRLTFNDPAIVQQVVMAESLVAAIPGTAPTPTAPF
EECHHHHHHHHHHHHHHCCCEEEEECCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DADALARQPLILYPARPRPSYADHVLSLFRGQGLQPRVVQEANELQTALGLVAAGLGITL
CHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
VPSSVQRLHRDDVRYVPINAPGFVSPVIMSYRSGDTSPYLARAVAWVLQQA
CCHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MELRHLRYFQTVAQELNVTRAAEKLHMAQPPLSRQIRQFEEEVGVALFDRVGRGLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
GRFLLEQSLQLTQRLEETLESTRRIGRNEKRWFGIGFVPSVLYGVLPELIRELRGDDSQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEE
EVGLTEMITVQQLEALKSGRIDLAFGRLTFNDPAIVQQVVMAESLVAAIPGTAPTPTAPF
EECHHHHHHHHHHHHHHCCCEEEEECCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DADALARQPLILYPARPRPSYADHVLSLFRGQGLQPRVVQEANELQTALGLVAAGLGITL
CHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
VPSSVQRLHRDDVRYVPINAPGFVSPVIMSYRSGDTSPYLARAVAWVLQQA
CCHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1688844 [H]