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The map label for this gene is qseC [H]

Identifier: 94313752

GI number: 94313752

Start: 1483786

End: 1485159

Strand: Direct

Name: qseC [H]

Synonym: Rmet_4830

Alternate gene names: 94313752

Gene position: 1483786-1485159 (Clockwise)

Preceding gene: 94313751

Following gene: 94313753

Centisome position: 57.51

GC content: 67.69

Gene sequence:

>1374_bases
ATGACGCTGCGGCGGCGGCTGATCCTGGCCGTCCTGGCCGCCGTGACGTTTGCATGGGTACTGACCAGCGCATTGATCTA
CCTGAGCGCCCAGGAAGAAATCAACGAGCTCTATGACACCGCGATGGTCCGCATGGCCCAGCAGATGCAGGCCCTGCTGC
CGCGCGTGCATACGCAAACCTCGCCGGCGCCGCCGGCGGCGAACGGGCCGATCCCCGGAGATGCCGATCTGGTCGACGAG
GGGTCGGCCGGGCTTGGTGATCTGGCGATCGCCGCATGGCGCCCCGACGGGGAGCCCCTGCACATCGACCCGGACGGAGA
TCACCTGCCCCGGCTGCCCGACGTCCAGGGGTTCACCGAGCGCAAGATCGACGGCGTGCCCTGGCGGCTCTACTACCTGA
ACGACCCGGCACAAGGCTGGCGCGTATGCGTCGGTCAGGTCAAGGCCGAGCGTGGCGAACTGATCGTCGCGTATCTGCAG
GCGCAGGTATTGCCTTGGGTCTTTGGTCTGCCGCTGCTGACCACGCTGCTGCTCTGGGGCGTGAGCCGCGCCCTGCATCC
CGTGCTGACGCTGTCGCAGGCCATTGCCGCGCGCGTGCCGGGCGATCCTACCCCGCTGACACTGCATGAGGTGCCGCGCG
AACTCGTGCCGCTGGTGACGGAAATGAACAAGCTGCTGAGCCGCGCCACGGCGCTGCTCGAACATGAACGCCGCCTGACC
GCCGATGCCGCGCACGAACTGCGCACGCCGCTGGCGGCCCTGAAGGCCCAGTGGGAAGTCGCACGCCGCTCCGACGATCC
GACCGAGCGCTCCCGCGCCGCCGCCAACGTCGAGGCCGGCATCGACGGTATGAGCCGGCTGGTCTCGCAACTGTTGACGA
TGAGCAGGCTCGAGGACGAAGAGGCGCCGCCCACGCGTGGCCCGGTGGACTGGCGGGAGGTGTCGCGGCAGGTGCTGTCG
GATTGCCTGCTGCTATCCGAACGGCGCAACGTCGACATGGAAGTGCTGTGGCCTCCGGCAGGCCAGCAACCGCTACCTGT
CAACGGCGACCCAACACTGCTCGGCACGATGCTTCGTAATCTGATGGACAACGCCATCCGCTATAGTCCGGCTGGCACGG
TGGTGACGCTGGCGTTCGAACCTGACCGGATTACCGTGTCCGATCGTGGCCCGGGCGTAGCACCGGAACTGCTGCGGCGG
CTCGGCGACCGCTTCTTCCGCGCCGCAGGCCAGCAGGAGCAAGGTAACGGACTCGGGATTTCGATCGCGCGCCGTGTGGC
CGTGCTTCATGGGCTCGCGCTGGAGTTCGCCAACCGTCAGGCCGGCGACGGCAGTGGACTGGTGGCTGCCATCCGCCTCA
ATGGCATGTATTGA

Upstream 100 bases:

>100_bases
ATCCCGGCATCGTGCGCACGCTGCGCGGCGCCGGCTACACCCTGGGCACGCTCGAGGCGATCGAGATCGGCACCTCGGAA
CCCGAGGGCGGGGATCGCGC

Downstream 100 bases:

>100_bases
TCGGCATTGGCCCACAATGACGGGAAATCGTCAGAACCAGCATCCGGCATGAGCACGCTCCGCGCCACCGAAACCCATCG
CGCCAGCCAAAGCGCCTGGG

Product: sensory histidine kinase in two-component regulatory system with QseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTLRRRLILAVLAAVTFAWVLTSALIYLSAQEEINELYDTAMVRMAQQMQALLPRVHTQTSPAPPAANGPIPGDADLVDE
GSAGLGDLAIAAWRPDGEPLHIDPDGDHLPRLPDVQGFTERKIDGVPWRLYYLNDPAQGWRVCVGQVKAERGELIVAYLQ
AQVLPWVFGLPLLTTLLLWGVSRALHPVLTLSQAIAARVPGDPTPLTLHEVPRELVPLVTEMNKLLSRATALLEHERRLT
ADAAHELRTPLAALKAQWEVARRSDDPTERSRAAANVEAGIDGMSRLVSQLLTMSRLEDEEAPPTRGPVDWREVSRQVLS
DCLLLSERRNVDMEVLWPPAGQQPLPVNGDPTLLGTMLRNLMDNAIRYSPAGTVVTLAFEPDRITVSDRGPGVAPELLRR
LGDRFFRAAGQQEQGNGLGISIARRVAVLHGLALEFANRQAGDGSGLVAAIRLNGMY

Sequences:

>Translated_457_residues
MTLRRRLILAVLAAVTFAWVLTSALIYLSAQEEINELYDTAMVRMAQQMQALLPRVHTQTSPAPPAANGPIPGDADLVDE
GSAGLGDLAIAAWRPDGEPLHIDPDGDHLPRLPDVQGFTERKIDGVPWRLYYLNDPAQGWRVCVGQVKAERGELIVAYLQ
AQVLPWVFGLPLLTTLLLWGVSRALHPVLTLSQAIAARVPGDPTPLTLHEVPRELVPLVTEMNKLLSRATALLEHERRLT
ADAAHELRTPLAALKAQWEVARRSDDPTERSRAAANVEAGIDGMSRLVSQLLTMSRLEDEEAPPTRGPVDWREVSRQVLS
DCLLLSERRNVDMEVLWPPAGQQPLPVNGDPTLLGTMLRNLMDNAIRYSPAGTVVTLAFEPDRITVSDRGPGVAPELLRR
LGDRFFRAAGQQEQGNGLGISIARRVAVLHGLALEFANRQAGDGSGLVAAIRLNGMY
>Mature_456_residues
TLRRRLILAVLAAVTFAWVLTSALIYLSAQEEINELYDTAMVRMAQQMQALLPRVHTQTSPAPPAANGPIPGDADLVDEG
SAGLGDLAIAAWRPDGEPLHIDPDGDHLPRLPDVQGFTERKIDGVPWRLYYLNDPAQGWRVCVGQVKAERGELIVAYLQA
QVLPWVFGLPLLTTLLLWGVSRALHPVLTLSQAIAARVPGDPTPLTLHEVPRELVPLVTEMNKLLSRATALLEHERRLTA
DAAHELRTPLAALKAQWEVARRSDDPTERSRAAANVEAGIDGMSRLVSQLLTMSRLEDEEAPPTRGPVDWREVSRQVLSD
CLLLSERRNVDMEVLWPPAGQQPLPVNGDPTLLGTMLRNLMDNAIRYSPAGTVVTLAFEPDRITVSDRGPGVAPELLRRL
GDRFFRAAGQQEQGNGLGISIARRVAVLHGLALEFANRQAGDGSGLVAAIRLNGMY

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=446, Percent_Identity=34.7533632286996, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=32.3024054982818, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786783, Length=270, Percent_Identity=28.8888888888889, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=205, Percent_Identity=31.219512195122, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=26.510067114094, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=26.6409266409266, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=290, Percent_Identity=28.2758620689655, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=222, Percent_Identity=27.4774774774775, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=26.5486725663717, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787894, Length=215, Percent_Identity=27.906976744186, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=28.0373831775701, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49977; Mature: 49846

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRRRLILAVLAAVTFAWVLTSALIYLSAQEEINELYDTAMVRMAQQMQALLPRVHTQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAPPAANGPIPGDADLVDEGSAGLGDLAIAAWRPDGEPLHIDPDGDHLPRLPDVQGFTE
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCHH
RKIDGVPWRLYYLNDPAQGWRVCVGQVKAERGELIVAYLQAQVLPWVFGLPLLTTLLLWG
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VSRALHPVLTLSQAIAARVPGDPTPLTLHEVPRELVPLVTEMNKLLSRATALLEHERRLT
HHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAAHELRTPLAALKAQWEVARRSDDPTERSRAAANVEAGIDGMSRLVSQLLTMSRLEDE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
EAPPTRGPVDWREVSRQVLSDCLLLSERRNVDMEVLWPPAGQQPLPVNGDPTLLGTMLRN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
LMDNAIRYSPAGTVVTLAFEPDRITVSDRGPGVAPELLRRLGDRFFRAAGQQEQGNGLGI
HHHHHHEECCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
SIARRVAVLHGLALEFANRQAGDGSGLVAAIRLNGMY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TLRRRLILAVLAAVTFAWVLTSALIYLSAQEEINELYDTAMVRMAQQMQALLPRVHTQT
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAPPAANGPIPGDADLVDEGSAGLGDLAIAAWRPDGEPLHIDPDGDHLPRLPDVQGFTE
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCHH
RKIDGVPWRLYYLNDPAQGWRVCVGQVKAERGELIVAYLQAQVLPWVFGLPLLTTLLLWG
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VSRALHPVLTLSQAIAARVPGDPTPLTLHEVPRELVPLVTEMNKLLSRATALLEHERRLT
HHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAAHELRTPLAALKAQWEVARRSDDPTERSRAAANVEAGIDGMSRLVSQLLTMSRLEDE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
EAPPTRGPVDWREVSRQVLSDCLLLSERRNVDMEVLWPPAGQQPLPVNGDPTLLGTMLRN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
LMDNAIRYSPAGTVVTLAFEPDRITVSDRGPGVAPELLRRLGDRFFRAAGQQEQGNGLGI
HHHHHHEECCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
SIARRVAVLHGLALEFANRQAGDGSGLVAAIRLNGMY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]