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The map label for this gene is tlcA [H]

Identifier: 94313705

GI number: 94313705

Start: 1426863

End: 1428224

Strand: Direct

Name: tlcA [H]

Synonym: Rmet_4783

Alternate gene names: 94313705

Gene position: 1426863-1428224 (Clockwise)

Preceding gene: 94313704

Following gene: 94313706

Centisome position: 55.3

GC content: 66.15

Gene sequence:

>1362_bases
ATGGACACTCCGGACCTGCCTCCCAATCCCGCCGGCCCCAGCGGGCTGCTTGGCATCGATCGGAGCGAAACCCCGGCCGT
GGTGGCGGGCTTCCTATTCTTCTTCTGCCTGTTCGCGAGCTACTTCATGCTGCGGCCCGTGCGGGAGACGATGGGCATCG
CTGGCGGCGTGCAGAATCTGCAGTGGCTGTTTACCGCGACGTTCGTGGTGATGCTCGTGGCCATCCCGTTCTACGGCGCA
TGTTGCAAGTGGCTGCCGCGCCGGCGCTTCGTGCCATGGGTCTACGCATTCTTCATCGCCAACCTCGTGGCGTTCGCGCT
GGTCACCCGCGCCCTGCCCGATAGTGTCTGGCTGGCCCGCGTGTTCTATGTCTGGATCTCGGTCTTCAACCTGTTTGTGG
TATCGGTGGCGTGGAGCCTGATGGCCGATGTATTTCGGCCCGAACAGGCCAAGCGACTGTTCGCCATCATCGCGGCGGGC
GCCAGCGCAGGTGGTCTCGCCGGACCCGTACTCGGCGCCGGGCTCGTGGGACACATCGGATTGACTGGCCTGATGTTGCT
GTCGGCCGCGTTGCTGGCCGCGACGCTGCCCGGGGTCGGCTACCTGTTCGCCTGGCGACGCAGGTATGGAGCGGGTGCGC
CCGGCAGCGAGACAGCTTCGGCGGCGGACCCCGCGCAACCGGTAGGCGGCGGACTCTGGGCTGGCCTGTCCCTGGTCCTC
CGTTCCCGGTACCTCATCGGTATCAGCCTGTTCGTGATCCTGCTGGCCACATCGAGCACGTTCCTCTACTTCGAGCAGGC
ACGACTGGTGGCGGCCACCTTCCACTCGCGTGCGCAGCAGACACAGGTATTCAGCGCGCTCGACGCCACCGTGCAGGCGC
TAACGATCCTCGTGCAGATCTTCTTTTCAGGACGCGTGGCGCGGCGCTACGGCGTGACCGCCCTGTTGACCGCCGTGCCG
CTGGCCGTGACCGGCGGCTTCCTGCTACTGGCGATGTGGCCCACATTCGGCGTGCTCGCGGCTGCCATGATCGTGCGGCG
CGTCGGGGAGTACGCGATGCTGCGCCCCGGCCGGGAGATGCTGTTTACGGTGGTCGACCCGGAAACCAAGTACAAGGCCA
AGAACGTCATCGATACCGCAATCTATCGTGCCGGCGATGCCGTCAGCGCCTGGGTGAAAACGGCGATCGACGCCTTGTCC
GGGCACCCCGCAACCGTGGCGCTGGCGGGCGCGGTACTCGCCATCGTGTGGGGCTGGCTAGGCTGGTGGCTTGGCCGCCA
GCACGAAGGTCAACTGACCGAACTGACAGTCGAGAAATCCTCACCGGCTGTACTCGCCCGGGGCCAGACCGGCAGCCGAT
AA

Upstream 100 bases:

>100_bases
CGCGTTCGGGCGGATGCCCGATACGCCCGAACGCGCCCGCATCGCAGCGGCGCTGGCCTGACTGCTGACCTGACTGCTGG
CCTGACCGTCGGCCCTCGCC

Downstream 100 bases:

>100_bases
TCGCCCGCCGGTCTGGCTCGTGTGCGCGGTTCGGCTTATAGTCGTGGCCTTGGTATTAGCCTGTCACGCGGACACGTGCC
GCCTCAATTCATTCGCTCGG

Product: putative transporter, major facilitator superfamily (MFS)

Products: NA

Alternate protein names: ADP/ATP translocase 1 [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDTPDLPPNPAGPSGLLGIDRSETPAVVAGFLFFFCLFASYFMLRPVRETMGIAGGVQNLQWLFTATFVVMLVAIPFYGA
CCKWLPRRRFVPWVYAFFIANLVAFALVTRALPDSVWLARVFYVWISVFNLFVVSVAWSLMADVFRPEQAKRLFAIIAAG
ASAGGLAGPVLGAGLVGHIGLTGLMLLSAALLAATLPGVGYLFAWRRRYGAGAPGSETASAADPAQPVGGGLWAGLSLVL
RSRYLIGISLFVILLATSSTFLYFEQARLVAATFHSRAQQTQVFSALDATVQALTILVQIFFSGRVARRYGVTALLTAVP
LAVTGGFLLLAMWPTFGVLAAAMIVRRVGEYAMLRPGREMLFTVVDPETKYKAKNVIDTAIYRAGDAVSAWVKTAIDALS
GHPATVALAGAVLAIVWGWLGWWLGRQHEGQLTELTVEKSSPAVLARGQTGSR

Sequences:

>Translated_453_residues
MDTPDLPPNPAGPSGLLGIDRSETPAVVAGFLFFFCLFASYFMLRPVRETMGIAGGVQNLQWLFTATFVVMLVAIPFYGA
CCKWLPRRRFVPWVYAFFIANLVAFALVTRALPDSVWLARVFYVWISVFNLFVVSVAWSLMADVFRPEQAKRLFAIIAAG
ASAGGLAGPVLGAGLVGHIGLTGLMLLSAALLAATLPGVGYLFAWRRRYGAGAPGSETASAADPAQPVGGGLWAGLSLVL
RSRYLIGISLFVILLATSSTFLYFEQARLVAATFHSRAQQTQVFSALDATVQALTILVQIFFSGRVARRYGVTALLTAVP
LAVTGGFLLLAMWPTFGVLAAAMIVRRVGEYAMLRPGREMLFTVVDPETKYKAKNVIDTAIYRAGDAVSAWVKTAIDALS
GHPATVALAGAVLAIVWGWLGWWLGRQHEGQLTELTVEKSSPAVLARGQTGSR
>Mature_453_residues
MDTPDLPPNPAGPSGLLGIDRSETPAVVAGFLFFFCLFASYFMLRPVRETMGIAGGVQNLQWLFTATFVVMLVAIPFYGA
CCKWLPRRRFVPWVYAFFIANLVAFALVTRALPDSVWLARVFYVWISVFNLFVVSVAWSLMADVFRPEQAKRLFAIIAAG
ASAGGLAGPVLGAGLVGHIGLTGLMLLSAALLAATLPGVGYLFAWRRRYGAGAPGSETASAADPAQPVGGGLWAGLSLVL
RSRYLIGISLFVILLATSSTFLYFEQARLVAATFHSRAQQTQVFSALDATVQALTILVQIFFSGRVARRYGVTALLTAVP
LAVTGGFLLLAMWPTFGVLAAAMIVRRVGEYAMLRPGREMLFTVVDPETKYKAKNVIDTAIYRAGDAVSAWVKTAIDALS
GHPATVALAGAVLAIVWGWLGWWLGRQHEGQLTELTVEKSSPAVLARGQTGSR

Specific function: Unknown

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48644; Mature: 48644

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCEEEEEEECCCCCEEECCCCCCC
>Mature Secondary Structure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HHHHCCCCCCCEEEEEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]