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The map label for this gene is kdgD [C]

Identifier: 94313658

GI number: 94313658

Start: 1380586

End: 1381500

Strand: Direct

Name: kdgD [C]

Synonym: Rmet_4736

Alternate gene names: 94313658

Gene position: 1380586-1381500 (Clockwise)

Preceding gene: 94313655

Following gene: 94313660

Centisome position: 53.51

GC content: 63.72

Gene sequence:

>915_bases
ATGACTACACCGCAAGAACTCAAGCAGATCATCTCGGAAGGCCTGCTCTCTTTCCCTATCACCGATTTCGACGCGCAAGG
CAACTTCCGCCCCGATACCTATATCGAGCGCCTGGAATGGCTGGCGCCCTACGGTGCGTCGGCGCTGTTTGCCGCCGGCG
GCACGGGTGAGTTCTTCTCGCTGACGCAGCAGGACTATTCGAACGTGATTCGCACCGCGGTGGAGACCTGCCGGGGCAAG
GTACCCATTCTTGCCGGCGCCGGTGGCGCGACTCGCGTGGCGATCGAATACGCGAAGGAAGCCGAGCGCCTGGGCGCCCA
CGGCGTGCTGCTGATGCCGCACTACCTGACCGAAGCCAGCGAAGAAGGCATCGCCAACCACATCGAAGAGGTTTGCAAGG
CGCTGAAAATCGGCGTGATCGTCTACAACCGCGCGAACTCCCGTATCGGCGCCGACCTGCTGGAACGCGTGGTCGACCGC
TGCCCCAACCTGATCGGCTTCAAGGACGGCGTGGGCGAGATCGAGGCGATGGTGCGCGTTCGCCGCAAGCTTGGTGACCG
GCTCGCATACCTGGGCGGCCTGCCTACCGCCGAAGTCTATGCCGCCGCCTACAAGGCGCTGGGCGTGCCCGTCTACTCGT
CGGCCGTGTTCAACTTCATCCCGAAGACCGCGATGGAGTTTTACCGCGCGATTGCCGCTGACGACCACGCCACGGTGGGT
CGCCTGATCGACGATTTCTTCCTGCCGTACCTGGACATCCGCAACCGCAAACAAGGCTACGCGGTGTCGATCGTCAAGGC
TGGCGCCAAGCTGGTTGGCCACGATGCCGGTCCGGTGCGCGCGCCGCTGACCGATCTGACCGAAGACGAAATGGCACGGC
TGGATGCGCTGATCCGCAAGCTCGGACCGCAGTAA

Upstream 100 bases:

>100_bases
GATGACTTATCTCGAAGCCATCGACCAGATGGAACGAGGCCATAACCCACCTTGTTCCCCACCAACCGCCATCTGCCATG
TGGCGATCAGGAAGCGTGAC

Downstream 100 bases:

>100_bases
GTTTCTCAGGTCGTCACTTTGAGAGTTTGGACAGAGCCGATTCGTCGGCTCTTTTTTTTGCGCGTCGCCAAATTAAAAAA
AAAACGCCAACCCGCGAAGG

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTTPQELKQIISEGLLSFPITDFDAQGNFRPDTYIERLEWLAPYGASALFAAGGTGEFFSLTQQDYSNVIRTAVETCRGK
VPILAGAGGATRVAIEYAKEAERLGAHGVLLMPHYLTEASEEGIANHIEEVCKALKIGVIVYNRANSRIGADLLERVVDR
CPNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMEFYRAIAADDHATVG
RLIDDFFLPYLDIRNRKQGYAVSIVKAGAKLVGHDAGPVRAPLTDLTEDEMARLDALIRKLGPQ

Sequences:

>Translated_304_residues
MTTPQELKQIISEGLLSFPITDFDAQGNFRPDTYIERLEWLAPYGASALFAAGGTGEFFSLTQQDYSNVIRTAVETCRGK
VPILAGAGGATRVAIEYAKEAERLGAHGVLLMPHYLTEASEEGIANHIEEVCKALKIGVIVYNRANSRIGADLLERVVDR
CPNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMEFYRAIAADDHATVG
RLIDDFFLPYLDIRNRKQGYAVSIVKAGAKLVGHDAGPVRAPLTDLTEDEMARLDALIRKLGPQ
>Mature_303_residues
TTPQELKQIISEGLLSFPITDFDAQGNFRPDTYIERLEWLAPYGASALFAAGGTGEFFSLTQQDYSNVIRTAVETCRGKV
PILAGAGGATRVAIEYAKEAERLGAHGVLLMPHYLTEASEEGIANHIEEVCKALKIGVIVYNRANSRIGADLLERVVDRC
PNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMEFYRAIAADDHATVGR
LIDDFFLPYLDIRNRKQGYAVSIVKAGAKLVGHDAGPVRAPLTDLTEDEMARLDALIRKLGPQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=234, Percent_Identity=25.6410256410256, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786463, Length=217, Percent_Identity=25.3456221198157, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082415, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 33122; Mature: 32991

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQELKQIISEGLLSFPITDFDAQGNFRPDTYIERLEWLAPYGASALFAAGGTGEFFS
CCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHH
LTQQDYSNVIRTAVETCRGKVPILAGAGGATRVAIEYAKEAERLGAHGVLLMPHYLTEAS
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
EEGIANHIEEVCKALKIGVIVYNRANSRIGADLLERVVDRCPNLIGFKDGVGEIEAMVRV
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMEFYRAIAADDHATVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDDFFLPYLDIRNRKQGYAVSIVKAGAKLVGHDAGPVRAPLTDLTEDEMARLDALIRK
HHHHHHHHHHHHHCCCCCCCEEHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHH
LGPQ
HCCC
>Mature Secondary Structure 
TTPQELKQIISEGLLSFPITDFDAQGNFRPDTYIERLEWLAPYGASALFAAGGTGEFFS
CCHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHH
LTQQDYSNVIRTAVETCRGKVPILAGAGGATRVAIEYAKEAERLGAHGVLLMPHYLTEAS
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
EEGIANHIEEVCKALKIGVIVYNRANSRIGADLLERVVDRCPNLIGFKDGVGEIEAMVRV
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMEFYRAIAADDHATVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDDFFLPYLDIRNRKQGYAVSIVKAGAKLVGHDAGPVRAPLTDLTEDEMARLDALIRK
HHHHHHHHHHHHHCCCCCCCEEHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHH
LGPQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA