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The map label for this gene is 94313556

Identifier: 94313556

GI number: 94313556

Start: 1264381

End: 1265274

Strand: Direct

Name: 94313556

Synonym: Rmet_4634

Alternate gene names: NA

Gene position: 1264381-1265274 (Clockwise)

Preceding gene: 94313554

Following gene: 94313559

Centisome position: 49.01

GC content: 63.31

Gene sequence:

>894_bases
GTGCTTGCTGGCGCCGCAGGTATGGCGGACTTTTCCCAATGCCGCCAGTTCTTTGCCCACAGCGCGCCACCGAGAGTCAC
CGCCACGTCCGACCTGAAGTTACGGCCGCTCTGCTATGACGCATTCGCGGTCATGCACTCGGGCCGCAGCAAGACGCCGG
TCTACGTCGCAGAGCGATTATCGAGATCCCAGCTTGTCGATGCCCGCGATGAAAAGCGGACCAACCAGTTCTTCGCCGAC
GCGCGATTACCGCGAGCCGAACGCGCCGAGCTGGACGACTACCGCGGCAGCGGATGGGATCGTGGTCACCTGGCGCCGGC
AGGCGATCAGCCCACTGCGCAGGCCATGGCGCAATCGTTCAGCCTGGCCAACATGACGCCACAGGCGCCAAAGAACAACC
GCGAGGCGTGGAGTTCGATCGAATCGGCTACGCGCAAGTACGCCATGCGGGCCAAGGGCGATGTCTACGTGATCTCTGGC
CCCGTATTCTCCGATCGCCCCCAAACCATCGGCGCGGGCCGCGTCTGGGTGCCCAGCTACTACTTCAAGCTGGTCTACGA
CCCCACCACGAATCGCGCCTGGGCGCACTGGATTGCGAACACCAACGAGGCTCGCCCTTCGAAGCCGATCAGCTATCACG
AACTGGTGAAACGTACCGGCATCGAATTCCTACCGGGCCTGATGCCCGGTGAAAACACGACTGCCACTGCGCCGGAGTTG
CGGGCGGAATCGACCACACGTGGCAACCGTGAGCCGAAGCGCGAGCCGAAGCGCGAGGGCGAGGATCTTGGCCAGGCGCT
CAGATCGCTGATTCAGCCCATCGCGCAGGATTTTGAGCGGATCATGCACACCTTGCTGCGGTGGTGGGCTCAGCTACGAC
ACATCATGGCCTGA

Upstream 100 bases:

>100_bases
CGAGTGAACGTATTGACGCTTGCGCAGTCAATCTGGTCCCACTCGTGACACCAGAACAATGAAGAAGTTAGTGATTTCCC
TGATCCTGGGGATGGCGCCC

Downstream 100 bases:

>100_bases
TCGTCCGATCGTCACCGCGTTCATGTTGCCGGCGCATCGGCGCCGATGGATTCCAGGGCCAGCGACTGCACCGCCTCATC
CACGCTGAGTTCATGCAGGG

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLAGAAGMADFSQCRQFFAHSAPPRVTATSDLKLRPLCYDAFAVMHSGRSKTPVYVAERLSRSQLVDARDEKRTNQFFAD
ARLPRAERAELDDYRGSGWDRGHLAPAGDQPTAQAMAQSFSLANMTPQAPKNNREAWSSIESATRKYAMRAKGDVYVISG
PVFSDRPQTIGAGRVWVPSYYFKLVYDPTTNRAWAHWIANTNEARPSKPISYHELVKRTGIEFLPGLMPGENTTATAPEL
RAESTTRGNREPKREPKREGEDLGQALRSLIQPIAQDFERIMHTLLRWWAQLRHIMA

Sequences:

>Translated_297_residues
MLAGAAGMADFSQCRQFFAHSAPPRVTATSDLKLRPLCYDAFAVMHSGRSKTPVYVAERLSRSQLVDARDEKRTNQFFAD
ARLPRAERAELDDYRGSGWDRGHLAPAGDQPTAQAMAQSFSLANMTPQAPKNNREAWSSIESATRKYAMRAKGDVYVISG
PVFSDRPQTIGAGRVWVPSYYFKLVYDPTTNRAWAHWIANTNEARPSKPISYHELVKRTGIEFLPGLMPGENTTATAPEL
RAESTTRGNREPKREPKREGEDLGQALRSLIQPIAQDFERIMHTLLRWWAQLRHIMA
>Mature_297_residues
MLAGAAGMADFSQCRQFFAHSAPPRVTATSDLKLRPLCYDAFAVMHSGRSKTPVYVAERLSRSQLVDARDEKRTNQFFAD
ARLPRAERAELDDYRGSGWDRGHLAPAGDQPTAQAMAQSFSLANMTPQAPKNNREAWSSIESATRKYAMRAKGDVYVISG
PVFSDRPQTIGAGRVWVPSYYFKLVYDPTTNRAWAHWIANTNEARPSKPISYHELVKRTGIEFLPGLMPGENTTATAPEL
RAESTTRGNREPKREPKREGEDLGQALRSLIQPIAQDFERIMHTLLRWWAQLRHIMA

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI224451073, Length=214, Percent_Identity=33.1775700934579, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI53759134, Length=222, Percent_Identity=32.8828828828829, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI224451075, Length=185, Percent_Identity=33.5135135135135, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17505967, Length=159, Percent_Identity=31.4465408805031, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322253, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581065, Length=170, Percent_Identity=32.9411764705882, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI20129899, Length=158, Percent_Identity=30.379746835443, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: 3.1.30.-

Molecular weight: Translated: 33435; Mature: 33435

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGAAGMADFSQCRQFFAHSAPPRVTATSDLKLRPLCYDAFAVMHSGRSKTPVYVAERL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHH
SRSQLVDARDEKRTNQFFADARLPRAERAELDDYRGSGWDRGHLAPAGDQPTAQAMAQSF
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLANMTPQAPKNNREAWSSIESATRKYAMRAKGDVYVISGPVFSDRPQTIGAGRVWVPSY
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEECCCE
YFKLVYDPTTNRAWAHWIANTNEARPSKPISYHELVKRTGIEFLPGLMPGENTTATAPEL
EEEEEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCHH
RAESTTRGNREPKREPKREGEDLGQALRSLIQPIAQDFERIMHTLLRWWAQLRHIMA
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLAGAAGMADFSQCRQFFAHSAPPRVTATSDLKLRPLCYDAFAVMHSGRSKTPVYVAERL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHH
SRSQLVDARDEKRTNQFFADARLPRAERAELDDYRGSGWDRGHLAPAGDQPTAQAMAQSF
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLANMTPQAPKNNREAWSSIESATRKYAMRAKGDVYVISGPVFSDRPQTIGAGRVWVPSY
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEECCCE
YFKLVYDPTTNRAWAHWIANTNEARPSKPISYHELVKRTGIEFLPGLMPGENTTATAPEL
EEEEEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCHH
RAESTTRGNREPKREPKREGEDLGQALRSLIQPIAQDFERIMHTLLRWWAQLRHIMA
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]