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The map label for this gene is virS [H]

Identifier: 94313554

GI number: 94313554

Start: 1262167

End: 1263174

Strand: Direct

Name: virS [H]

Synonym: Rmet_4632

Alternate gene names: 94313554

Gene position: 1262167-1263174 (Clockwise)

Preceding gene: 94313553

Following gene: 94313556

Centisome position: 48.92

GC content: 64.68

Gene sequence:

>1008_bases
ATGAGTACTCTGATTCGCAGTGCCCTCCTCGTCAAATTCTCCGAAGTGTCCCGCACCGTTGGCATCGACGCCGACCGGCT
GATCCAGCATGTCGGTGGCGACAGATCCTGCATGTTCTCGCCGGATCTGCACGTGCCGGAACCGTGGCTCGCCCGGATGC
TGGAAAGCAGCGAGCAGGCCGGCCAAGGCGCATCGGCGTCGATCGGCTTGCTGATGGCGGAAACCTGGCGGATGTCGGAT
TTCGGCCCGATCAGTCTGCTACTGCAGCATCAGCCCACGCTGCGCCACGCACTGGGCCAGCTAGAGACCTACCGTCATCT
GCTCAGCGAATCCGTCGCGGTCCATGTGGAGGAGTTCGACGATATCGCCATCGTCCACCAGCAGGTCATTACCGAGCGGC
CTAATCCTGGCCGTCAGCCGGTGGAACTGTCGGTCGGCGCGTTGCAGAGCCTGATGAAGTCGATGCTCGGTGGTCACTGG
AAGCCGCGTAGCGTTCATTTCTCTCATGCCGCGCCGGCGAGCCTGCATGTGCACCAGCGCCTGTTCGGCACGCGGGTTGA
GTTCGGCTGCGACTTCGATGGCATCACGATCGACCGGCATGACCTCGATCGGCCCAATCCGCTCGGCGACGTCAATCTGG
CCCGCTATGCCAAGGAGTTTCTCGACGAGCGTCCGCATGGCAAGCAGGCGTCCACGGCATCCAACGTGCGCCGGGCCATT
CAGTTGCTGCTGCCGCGTGGGCGCAGTGGCATCGAACAGGTCGGCCAGCAACTCGGCATGAGTTCGCGCACGCTACAGCG
GCGGCTGGAGCAGGAAGGCGTCGAGTTCTCCACGCTGCTCGGCGAGGTGCGCAGGGGGCTGGCCAACCGCTATCTGGGAG
ACCAGCGGTACCCGGTGTCGCAGGTGGCCACGTTGCTCGGTTTCTCCGAGGTCAGCACGTTCTCGCGCTGGTTCGCCGCG
CAGTTCGGTGTGTCCCCGACACGCTGGAGGGCGGGCCAGCCCGCGTGA

Upstream 100 bases:

>100_bases
GCCCCGGCAAAGGGGCTGGAGCCGGATCAGGGCAATCCCGTCTTGTCCGGTTCCCCGAATCATCAGATAACACTTGCCGC
TTCTCCGCCCCCGTGATGCC

Downstream 100 bases:

>100_bases
GCGGCCGGCCCTGCGCTGTTCGGTTGGGCTCGGTTGGGCGCGGATCAGAACGGACGATCGCCCTTGATTGTGGCTCGCTC
CATCCGGCGTGGCGCAGGCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSTLIRSALLVKFSEVSRTVGIDADRLIQHVGGDRSCMFSPDLHVPEPWLARMLESSEQAGQGASASIGLLMAETWRMSD
FGPISLLLQHQPTLRHALGQLETYRHLLSESVAVHVEEFDDIAIVHQQVITERPNPGRQPVELSVGALQSLMKSMLGGHW
KPRSVHFSHAAPASLHVHQRLFGTRVEFGCDFDGITIDRHDLDRPNPLGDVNLARYAKEFLDERPHGKQASTASNVRRAI
QLLLPRGRSGIEQVGQQLGMSSRTLQRRLEQEGVEFSTLLGEVRRGLANRYLGDQRYPVSQVATLLGFSEVSTFSRWFAA
QFGVSPTRWRAGQPA

Sequences:

>Translated_335_residues
MSTLIRSALLVKFSEVSRTVGIDADRLIQHVGGDRSCMFSPDLHVPEPWLARMLESSEQAGQGASASIGLLMAETWRMSD
FGPISLLLQHQPTLRHALGQLETYRHLLSESVAVHVEEFDDIAIVHQQVITERPNPGRQPVELSVGALQSLMKSMLGGHW
KPRSVHFSHAAPASLHVHQRLFGTRVEFGCDFDGITIDRHDLDRPNPLGDVNLARYAKEFLDERPHGKQASTASNVRRAI
QLLLPRGRSGIEQVGQQLGMSSRTLQRRLEQEGVEFSTLLGEVRRGLANRYLGDQRYPVSQVATLLGFSEVSTFSRWFAA
QFGVSPTRWRAGQPA
>Mature_334_residues
STLIRSALLVKFSEVSRTVGIDADRLIQHVGGDRSCMFSPDLHVPEPWLARMLESSEQAGQGASASIGLLMAETWRMSDF
GPISLLLQHQPTLRHALGQLETYRHLLSESVAVHVEEFDDIAIVHQQVITERPNPGRQPVELSVGALQSLMKSMLGGHWK
PRSVHFSHAAPASLHVHQRLFGTRVEFGCDFDGITIDRHDLDRPNPLGDVNLARYAKEFLDERPHGKQASTASNVRRAIQ
LLLPRGRSGIEQVGQQLGMSSRTLQRRLEQEGVEFSTLLGEVRRGLANRYLGDQRYPVSQVATLLGFSEVSTFSRWFAAQ
FGVSPTRWRAGQPA

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37310; Mature: 37179

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLIRSALLVKFSEVSRTVGIDADRLIQHVGGDRSCMFSPDLHVPEPWLARMLESSEQA
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHH
GQGASASIGLLMAETWRMSDFGPISLLLQHQPTLRHALGQLETYRHLLSESVAVHVEEFD
CCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
DIAIVHQQVITERPNPGRQPVELSVGALQSLMKSMLGGHWKPRSVHFSHAAPASLHVHQR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHH
LFGTRVEFGCDFDGITIDRHDLDRPNPLGDVNLARYAKEFLDERPHGKQASTASNVRRAI
HHHCHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QLLLPRGRSGIEQVGQQLGMSSRTLQRRLEQEGVEFSTLLGEVRRGLANRYLGDQRYPVS
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHH
QVATLLGFSEVSTFSRWFAAQFGVSPTRWRAGQPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STLIRSALLVKFSEVSRTVGIDADRLIQHVGGDRSCMFSPDLHVPEPWLARMLESSEQA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHH
GQGASASIGLLMAETWRMSDFGPISLLLQHQPTLRHALGQLETYRHLLSESVAVHVEEFD
CCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
DIAIVHQQVITERPNPGRQPVELSVGALQSLMKSMLGGHWKPRSVHFSHAAPASLHVHQR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHH
LFGTRVEFGCDFDGITIDRHDLDRPNPLGDVNLARYAKEFLDERPHGKQASTASNVRRAI
HHHCHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QLLLPRGRSGIEQVGQQLGMSSRTLQRRLEQEGVEFSTLLGEVRRGLANRYLGDQRYPVS
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHH
QVATLLGFSEVSTFSRWFAAQFGVSPTRWRAGQPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]