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The map label for this gene is yiaV [H]

Identifier: 94313542

GI number: 94313542

Start: 1247243

End: 1248421

Strand: Reverse

Name: yiaV [H]

Synonym: Rmet_4620

Alternate gene names: 94313542

Gene position: 1248421-1247243 (Counterclockwise)

Preceding gene: 94313543

Following gene: 94313541

Centisome position: 48.39

GC content: 64.21

Gene sequence:

>1179_bases
ATGGATGCGCTGATACTCGGTGTCTACGCGCTGGCCGTCTGGCTGGTCTTCTTCAAGTTCAAGTGGCTGCCGTGGAACAC
CCCGACCATGGTGATCGTGGTCACCATCCCGGTGGTGGCGATGACGGTGCTGGTCCTGACGCTGAACGTGGTGGCGCCGT
CCTCGCATGACGTGCGGGTGGTCGGCAAGGTCCTGCAGGTGGTGCCGCAAGTGAGGGGCCGCATTGTCGAACTGCCGGCC
GAAGGCAACCGAAGCTACAAGAAGGGCGACGTGCTGCTGCGTATCGATCCAACGCCATATCAGGCGTCGGTCAGGCAGCT
CGAAGGCAGGCTGATGGCCGACGATGCGGCGCTCGCCGAAGCCGAAGCGGCGGCACGTCAGCTAAGTGAATCGGTGCGTG
GCGCTGCGGGGCGGGTGAGTGCCGTTCAGGCCAGGCTGTCGCTGGCCCGCAGGCGGGTCAGCGAGCACGATGCGCTGCTT
TCCGCCGGTGCCGGGTCGAAGTTCGACCGTGAGGAAGCCAGCGCTCGCGAGCATGAACTGGAAGGCGATCTGCTCAGTGC
CCAGGCCGCGGAGGAAGAGGCCCGGCAGAAGCTATCGGCCAAAAGCCAGGGAGAGTTTGTCGCGATCGCCACCGCGCGCG
CCAAGCGCGCCGAGACCGAAGTCATGCTCGAGAACGCCCGCTGGGAACTGGAGCAGACGGTCTATCGGGCGCCGTCGGAC
GGCCGCGTCGTGAACTTGCAGGTGCGCGTCGGCACTATGCTCGTGCCGTTCCCGTTCTCCCCGGCATTCAGCTTCGTGGA
GGATCAGCAGGAGGTCCTGGCCTTCTATCATCAGAACGAGCTCTACAACGTCAAAACGGGCGATCTCGCTGAAATCTACC
TGCCAACGGCCCCGGGCGAAATCATCAAGGCCCGCGTCGATTCGATCGTCTGGGCCCAGTCGCAAGGCCAGTTCGCACAG
GGCGGCATGATTCCGAACACCGGGGCCACGGATGTGGTGCCGAACCGGTTCGCGGTCAAGCTTGCGCTCCGCGACGAATC
GAGCGGACTGACGCTACCCGTCGGCGCGGTGGGTGCTGGCGCGATCTACACGGAGCGCATGGAGATGTTCCATATCATCC
GCATGGTCTTCCTGCGCGTCAGTTCCAAGCTGAACTACCTCGTGTTCAAGCTGCACTAG

Upstream 100 bases:

>100_bases
TACCAAGCCCGTGTTCTACCGGGCGGCCTACGGCACCGACCAGGCGCCGGAAGACACTGAAGCGCCCGGCGAGATTCGCG
CCGGAAAGGAGCCGATCTGA

Downstream 100 bases:

>100_bases
GCCACGGGAGACAAGCTTATGTCGTCATCTCAGATCAAGAAGTCCCTGCTGCTGGCGCTGCCGGTTGCCATGCTTGCCGG
GTGCGCCCTGCAGACCCCGC

Product: putative membrane fusion protein of efflux pump HlyD family v

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDALILGVYALAVWLVFFKFKWLPWNTPTMVIVVTIPVVAMTVLVLTLNVVAPSSHDVRVVGKVLQVVPQVRGRIVELPA
EGNRSYKKGDVLLRIDPTPYQASVRQLEGRLMADDAALAEAEAAARQLSESVRGAAGRVSAVQARLSLARRRVSEHDALL
SAGAGSKFDREEASAREHELEGDLLSAQAAEEEARQKLSAKSQGEFVAIATARAKRAETEVMLENARWELEQTVYRAPSD
GRVVNLQVRVGTMLVPFPFSPAFSFVEDQQEVLAFYHQNELYNVKTGDLAEIYLPTAPGEIIKARVDSIVWAQSQGQFAQ
GGMIPNTGATDVVPNRFAVKLALRDESSGLTLPVGAVGAGAIYTERMEMFHIIRMVFLRVSSKLNYLVFKLH

Sequences:

>Translated_392_residues
MDALILGVYALAVWLVFFKFKWLPWNTPTMVIVVTIPVVAMTVLVLTLNVVAPSSHDVRVVGKVLQVVPQVRGRIVELPA
EGNRSYKKGDVLLRIDPTPYQASVRQLEGRLMADDAALAEAEAAARQLSESVRGAAGRVSAVQARLSLARRRVSEHDALL
SAGAGSKFDREEASAREHELEGDLLSAQAAEEEARQKLSAKSQGEFVAIATARAKRAETEVMLENARWELEQTVYRAPSD
GRVVNLQVRVGTMLVPFPFSPAFSFVEDQQEVLAFYHQNELYNVKTGDLAEIYLPTAPGEIIKARVDSIVWAQSQGQFAQ
GGMIPNTGATDVVPNRFAVKLALRDESSGLTLPVGAVGAGAIYTERMEMFHIIRMVFLRVSSKLNYLVFKLH
>Mature_392_residues
MDALILGVYALAVWLVFFKFKWLPWNTPTMVIVVTIPVVAMTVLVLTLNVVAPSSHDVRVVGKVLQVVPQVRGRIVELPA
EGNRSYKKGDVLLRIDPTPYQASVRQLEGRLMADDAALAEAEAAARQLSESVRGAAGRVSAVQARLSLARRRVSEHDALL
SAGAGSKFDREEASAREHELEGDLLSAQAAEEEARQKLSAKSQGEFVAIATARAKRAETEVMLENARWELEQTVYRAPSD
GRVVNLQVRVGTMLVPFPFSPAFSFVEDQQEVLAFYHQNELYNVKTGDLAEIYLPTAPGEIIKARVDSIVWAQSQGQFAQ
GGMIPNTGATDVVPNRFAVKLALRDESSGLTLPVGAVGAGAIYTERMEMFHIIRMVFLRVSSKLNYLVFKLH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=396, Percent_Identity=29.5454545454545, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790024, Length=393, Percent_Identity=29.2620865139949, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790519, Length=283, Percent_Identity=31.4487632508834, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43054; Mature: 43054

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALILGVYALAVWLVFFKFKWLPWNTPTMVIVVTIPVVAMTVLVLTLNVVAPSSHDVRV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VGKVLQVVPQVRGRIVELPAEGNRSYKKGDVLLRIDPTPYQASVRQLEGRLMADDAALAE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEECHHHHHH
AEAAARQLSESVRGAAGRVSAVQARLSLARRRVSEHDALLSAGAGSKFDREEASAREHEL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
EGDLLSAQAAEEEARQKLSAKSQGEFVAIATARAKRAETEVMLENARWELEQTVYRAPSD
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHCCCCC
GRVVNLQVRVGTMLVPFPFSPAFSFVEDQQEVLAFYHQNELYNVKTGDLAEIYLPTAPGE
CCEEEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHH
IIKARVDSIVWAQSQGQFAQGGMIPNTGATDVVPNRFAVKLALRDESSGLTLPVGAVGAG
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCC
AIYTERMEMFHIIRMVFLRVSSKLNYLVFKLH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MDALILGVYALAVWLVFFKFKWLPWNTPTMVIVVTIPVVAMTVLVLTLNVVAPSSHDVRV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VGKVLQVVPQVRGRIVELPAEGNRSYKKGDVLLRIDPTPYQASVRQLEGRLMADDAALAE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEECHHHHHH
AEAAARQLSESVRGAAGRVSAVQARLSLARRRVSEHDALLSAGAGSKFDREEASAREHEL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
EGDLLSAQAAEEEARQKLSAKSQGEFVAIATARAKRAETEVMLENARWELEQTVYRAPSD
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHCCCCC
GRVVNLQVRVGTMLVPFPFSPAFSFVEDQQEVLAFYHQNELYNVKTGDLAEIYLPTAPGE
CCEEEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHH
IIKARVDSIVWAQSQGQFAQGGMIPNTGATDVVPNRFAVKLALRDESSGLTLPVGAVGAG
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCC
AIYTERMEMFHIIRMVFLRVSSKLNYLVFKLH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]