Click here to switch to the map view.

The map label for this gene is mdtO [H]

Identifier: 94313436

GI number: 94313436

Start: 1113378

End: 1115369

Strand: Direct

Name: mdtO [H]

Synonym: Rmet_4511

Alternate gene names: 94313436

Gene position: 1113378-1115369 (Clockwise)

Preceding gene: 94313435

Following gene: 94313437

Centisome position: 43.15

GC content: 67.02

Gene sequence:

>1992_bases
ATGGCGCAGCCTGCCGCTGACAAGCTGCGCCTCGGCCTGGGCGACATCGGCGCCCTGCTCGCGCCGACGCCCGGCCGGGC
GGCCGCCACCACCCGTATCACCGTGGCGAGCGTGCTGACGGTGCTCGTCACCGCCATCTACGGCACGCCGGAAGCCGCTA
TCTCTGCCTACGTCATCTTCTTCATCAACCGGGAAGATCGCACCGTCAGCATCGTGATGAGTGTGGCAGCGTTGGTGCTG
GTCAGCCTGATCATTGGCCTGGTGATCGTGCTGGCCAACTTCAGTGTCGACGATTCGCTGCGGCGGCTGGCCTTCATGGC
CGTCCTGTCGGCCGCGCTGCTGTTTCTCACGTCGGCCAGCAAGCTTCGGCCGATCGGCGCCATCGTGGCAATGATCATCG
GCTTCGGGCTCGATGAACTCGGACTGGTCCCGGGCGGAGAGGCCGCCACGCGCGCCCTGCTCTACGCGTGGCTGATGGTA
GCGATTCCGATTGGCGTGAATGTAGCGGTCAATCTCGTGATGGGACCTTCGCCACGCCGGTTGGCGGGCGACCGGCTCGC
CCATTGCCTGCGCATGGCTGCTGCCAGCCTGCGACAGGAGGACGCCGCCCCGGCCATGCTCGTCCCGCTGCTGCGCGACG
GCACGCAACCCGTCGGCATGTGGCTGAAGCTGGCGAAGATCGAGGGGCTGTCCCGCGCCGAAGACCTTGCGGCGCTGCGA
CGGGCCGCCGCGTCGACCACGGCCATTCTGATCGCCGCCGACATGGCGCTCCGGCAGCCGAACGCCCGCTTGCCGGCCGC
CTTCCGCACCCCGATTGCGGACACGCTCGATCAGATGGCGGCGATGCTCCAGGCGGGCGGCTACCCGGTGGAAATCACGC
TGGCGCTTCCCGCGCTCGAATCGCTCGCGCCAGTGCAGCAGGCCATCGCCGTGGAACTGCGTGACGCCATCGTCGGCTTC
ACCGATGCGGATGCACCGAGCGCACAGGCCAACGCGGCCCTCGCCGAGGCCCCCAACGCAACGGAAGAGAAAAAAGGCGG
ATTCCTCAGCGCGGATGCCTTCACGAATCCCGAGCACATCCGCTACGCGCTCAAGACCACCGGCGCGGCAATGTTCTGCT
ACGTGCTCTACCAGCAACTGAACTGGCCTGGCATCCATACCTGCTTCATCACGGTCTACCTGGTATCGCTGTCGACCGCG
GCCGAAACGGTCGAAAAGCTCTCGCTGCGGCTGGCTGGCTGCCTGATCGGCGCGCTGATCGGCACTGCCGCGCTGGTCTA
TGTCGTACCGTCGATCGATTCCGTCGGTGGGCTCCTGATGCTGGTCTTCACGGGCACATGGGTAGCCGCCTGGGTCGCGC
AGGGGTCGCCCCGTATCTCGTATGCGGGCTTCCAGATCGCGTTCGCGTTCTACCTCTGCGTGATTCAGGGAGCCGGACCC
GGCTACGACCTGACGATTGCGCGGGACCGGACCATCGGCATCGTGATCGGCAATCTGGTGACATTCCTGGTCTTCACGCG
CATCTGGCCGGTCAGCATTTCAGGGCGGATCGAAGCCGCGCTCCATGACATGGTGCGGCAATGGCGGCAACTAATTGCCA
CGCCGCGGCGCGAAGCACAGCGGCAAAACGCCGCCGCCGCGTTGGCGCTGCATGGCGCCATCACGCAGGACCTGATCCTG
GCCAGATATGAGCCGGCATTGGTCGGCCCCGGCACTGACTGGATCGAGGCCCGCCAGCGCCATCTGGCAACGCTGGACGC
CGTAGCCGGTCCGCTTTTTCTGCTGGCGGAGCGATTTCCGGGCGATCCGGAGGTCGATCGACGTCTGCAGGCCGTTCGCA
TGGATGGCCACGCGCCCGTAACAAGCGCGGCCCCGCTTTCTCCGCAGCATTCCCCGCGCGACGCGCTGCTCGCCCTGGTT
GACCGGCATCTCGCCGCTCCGCGCCAGGACGATCCGCCGGCCGCCGCCACCGGATCACCGTTGCATGCCTAG

Upstream 100 bases:

>100_bases
TGGGTACGCGTCGCCAAGCGTTTCCCGGTTCGCATCCGGCTCGAAGATCCGCCCGAGACGCTGGCCCGCGCCGGCGCCAG
CGCAAACGTCGAGATCCGGC

Downstream 100 bases:

>100_bases
AACAGGATTACCGATTTTCCCGCTGATGCTGCTCGGCGCCAGCCTTGCCGGTTGCGCGACGGCGTCGCTCGACCTTGCGC
CGGAGCAGCCCGATCGTCCG

Product: Fusaric acid resistance protein conserved region/ multidrug efflux system component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MAQPAADKLRLGLGDIGALLAPTPGRAAATTRITVASVLTVLVTAIYGTPEAAISAYVIFFINREDRTVSIVMSVAALVL
VSLIIGLVIVLANFSVDDSLRRLAFMAVLSAALLFLTSASKLRPIGAIVAMIIGFGLDELGLVPGGEAATRALLYAWLMV
AIPIGVNVAVNLVMGPSPRRLAGDRLAHCLRMAAASLRQEDAAPAMLVPLLRDGTQPVGMWLKLAKIEGLSRAEDLAALR
RAAASTTAILIAADMALRQPNARLPAAFRTPIADTLDQMAAMLQAGGYPVEITLALPALESLAPVQQAIAVELRDAIVGF
TDADAPSAQANAALAEAPNATEEKKGGFLSADAFTNPEHIRYALKTTGAAMFCYVLYQQLNWPGIHTCFITVYLVSLSTA
AETVEKLSLRLAGCLIGALIGTAALVYVVPSIDSVGGLLMLVFTGTWVAAWVAQGSPRISYAGFQIAFAFYLCVIQGAGP
GYDLTIARDRTIGIVIGNLVTFLVFTRIWPVSISGRIEAALHDMVRQWRQLIATPRREAQRQNAAAALALHGAITQDLIL
ARYEPALVGPGTDWIEARQRHLATLDAVAGPLFLLAERFPGDPEVDRRLQAVRMDGHAPVTSAAPLSPQHSPRDALLALV
DRHLAAPRQDDPPAAATGSPLHA

Sequences:

>Translated_663_residues
MAQPAADKLRLGLGDIGALLAPTPGRAAATTRITVASVLTVLVTAIYGTPEAAISAYVIFFINREDRTVSIVMSVAALVL
VSLIIGLVIVLANFSVDDSLRRLAFMAVLSAALLFLTSASKLRPIGAIVAMIIGFGLDELGLVPGGEAATRALLYAWLMV
AIPIGVNVAVNLVMGPSPRRLAGDRLAHCLRMAAASLRQEDAAPAMLVPLLRDGTQPVGMWLKLAKIEGLSRAEDLAALR
RAAASTTAILIAADMALRQPNARLPAAFRTPIADTLDQMAAMLQAGGYPVEITLALPALESLAPVQQAIAVELRDAIVGF
TDADAPSAQANAALAEAPNATEEKKGGFLSADAFTNPEHIRYALKTTGAAMFCYVLYQQLNWPGIHTCFITVYLVSLSTA
AETVEKLSLRLAGCLIGALIGTAALVYVVPSIDSVGGLLMLVFTGTWVAAWVAQGSPRISYAGFQIAFAFYLCVIQGAGP
GYDLTIARDRTIGIVIGNLVTFLVFTRIWPVSISGRIEAALHDMVRQWRQLIATPRREAQRQNAAAALALHGAITQDLIL
ARYEPALVGPGTDWIEARQRHLATLDAVAGPLFLLAERFPGDPEVDRRLQAVRMDGHAPVTSAAPLSPQHSPRDALLALV
DRHLAAPRQDDPPAAATGSPLHA
>Mature_662_residues
AQPAADKLRLGLGDIGALLAPTPGRAAATTRITVASVLTVLVTAIYGTPEAAISAYVIFFINREDRTVSIVMSVAALVLV
SLIIGLVIVLANFSVDDSLRRLAFMAVLSAALLFLTSASKLRPIGAIVAMIIGFGLDELGLVPGGEAATRALLYAWLMVA
IPIGVNVAVNLVMGPSPRRLAGDRLAHCLRMAAASLRQEDAAPAMLVPLLRDGTQPVGMWLKLAKIEGLSRAEDLAALRR
AAASTTAILIAADMALRQPNARLPAAFRTPIADTLDQMAAMLQAGGYPVEITLALPALESLAPVQQAIAVELRDAIVGFT
DADAPSAQANAALAEAPNATEEKKGGFLSADAFTNPEHIRYALKTTGAAMFCYVLYQQLNWPGIHTCFITVYLVSLSTAA
ETVEKLSLRLAGCLIGALIGTAALVYVVPSIDSVGGLLMLVFTGTWVAAWVAQGSPRISYAGFQIAFAFYLCVIQGAGPG
YDLTIARDRTIGIVIGNLVTFLVFTRIWPVSISGRIEAALHDMVRQWRQLIATPRREAQRQNAAAALALHGAITQDLILA
RYEPALVGPGTDWIEARQRHLATLDAVAGPLFLLAERFPGDPEVDRRLQAVRMDGHAPVTSAAPLSPQHSPRDALLALVD
RHLAAPRQDDPPAAATGSPLHA

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MdtO family [H]

Homologues:

Organism=Escherichia coli, GI87082367, Length=211, Percent_Identity=33.6492890995261, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 70086; Mature: 69954

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPAADKLRLGLGDIGALLAPTPGRAAATTRITVASVLTVLVTAIYGTPEAAISAYVIF
CCCCCCHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEE
FINREDRTVSIVMSVAALVLVSLIIGLVIVLANFSVDDSLRRLAFMAVLSAALLFLTSAS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHH
KLRPIGAIVAMIIGFGLDELGLVPGGEAATRALLYAWLMVAIPIGVNVAVNLVMGPSPRR
HCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
LAGDRLAHCLRMAAASLRQEDAAPAMLVPLLRDGTQPVGMWLKLAKIEGLSRAEDLAALR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
RAAASTTAILIAADMALRQPNARLPAAFRTPIADTLDQMAAMLQAGGYPVEITLALPALE
HHHHHHHEEEEEHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHH
SLAPVQQAIAVELRDAIVGFTDADAPSAQANAALAEAPNATEEKKGGFLSADAFTNPEHI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHCCCEEECCCCCCHHHH
RYALKTTGAAMFCYVLYQQLNWPGIHTCFITVYLVSLSTAAETVEKLSLRLAGCLIGALI
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTAALVYVVPSIDSVGGLLMLVFTGTWVAAWVAQGSPRISYAGFQIAFAFYLCVIQGAGP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCC
GYDLTIARDRTIGIVIGNLVTFLVFTRIWPVSISGRIEAALHDMVRQWRQLIATPRREAQ
CEEEEEECCCEEEHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHH
RQNAAAALALHGAITQDLILARYEPALVGPGTDWIEARQRHLATLDAVAGPLFLLAERFP
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPEVDRRLQAVRMDGHAPVTSAAPLSPQHSPRDALLALVDRHLAAPRQDDPPAAATGSP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LHA
CCC
>Mature Secondary Structure 
AQPAADKLRLGLGDIGALLAPTPGRAAATTRITVASVLTVLVTAIYGTPEAAISAYVIF
CCCCCHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEE
FINREDRTVSIVMSVAALVLVSLIIGLVIVLANFSVDDSLRRLAFMAVLSAALLFLTSAS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHH
KLRPIGAIVAMIIGFGLDELGLVPGGEAATRALLYAWLMVAIPIGVNVAVNLVMGPSPRR
HCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
LAGDRLAHCLRMAAASLRQEDAAPAMLVPLLRDGTQPVGMWLKLAKIEGLSRAEDLAALR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
RAAASTTAILIAADMALRQPNARLPAAFRTPIADTLDQMAAMLQAGGYPVEITLALPALE
HHHHHHHEEEEEHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHH
SLAPVQQAIAVELRDAIVGFTDADAPSAQANAALAEAPNATEEKKGGFLSADAFTNPEHI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHCCCEEECCCCCCHHHH
RYALKTTGAAMFCYVLYQQLNWPGIHTCFITVYLVSLSTAAETVEKLSLRLAGCLIGALI
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTAALVYVVPSIDSVGGLLMLVFTGTWVAAWVAQGSPRISYAGFQIAFAFYLCVIQGAGP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCC
GYDLTIARDRTIGIVIGNLVTFLVFTRIWPVSISGRIEAALHDMVRQWRQLIATPRREAQ
CEEEEEECCCEEEHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHH
RQNAAAALALHGAITQDLILARYEPALVGPGTDWIEARQRHLATLDAVAGPLFLLAERFP
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPEVDRRLQAVRMDGHAPVTSAAPLSPQHSPRDALLALVDRHLAAPRQDDPPAAATGSP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LHA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]