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The map label for this gene is abgR [H]

Identifier: 94313430

GI number: 94313430

Start: 1107028

End: 1107954

Strand: Reverse

Name: abgR [H]

Synonym: Rmet_4505

Alternate gene names: 94313430

Gene position: 1107954-1107028 (Counterclockwise)

Preceding gene: 94313433

Following gene: 94313428

Centisome position: 42.94

GC content: 63.97

Gene sequence:

>927_bases
GTGAAGCTACATCAACTGCGCATTCTGCTGGCCGTGGCGCAGCACGGCAGCATCCACGAGGCGTCACGCGGGCTGCATAT
TTCGCAGCCCGCGCTATCCAAGGCCATCGCTGAACTGGAGCGAGAGCTTGGCGTCACGCTGCTGTCCCGCTCCGTGCGCG
GTGTGAGTCTGACTGCGTACGGGATGGCGCTGGTCAAGCGCGCCACCGTAGTCGAGCAGGAACTGCGACACGCGCTGGAA
GACATCGAATCCATACGCGGCCATGCGGAAGCCGAACTCAATATCGGGTTTACCGCCGTGGCCTCCAGTGGCCCGCTGCC
CGATGCCATGGCGGCGTTGCGCAAGCGCTTTCCCAATGTCGCCTTGCGTGGCTTCGAGCAGCGCCCGCAGCAGATTCAGG
AGGGGCTGCGGGAGGGGCGGCTTGATCTCGGGCTGATCTCCACCAATAGCGGGCCGGGAGCGGGCGGACTCCAGTGGGAG
TCCTTGTTCTCGGTGCCGATGCGTCTGGCCGTGCGGCCGGGCCATCCACTACGGCGTGTCCGCCGGCTGCGTCCGCTGCT
GGATGCCGACTGGCTGGTGCTGGACCCGCTCGATGACCCCGGCAGCCCGATATCAAGCCTGATGCGATTGCACCGACTGG
AAATACCGCGCCGGGTCGTGCAGAGCGCATCCAATCTACTGGGGCTGCAGCTGGCCACCAAGACCGACCTTATCAGCATG
TGGTCGGACTTCGTTTTCCGGGGCACTGGCGGGCCATTGCGCATGGACCCCGGTTCGCTGGAGGTGCTAGCGATGGAAGA
CGAACTGCCGGACTTCAACGTCTACCTGGTCTATCGCTCGATGGACCTGATGACGCATGTCTGTGCCGAGTTCAGCAAGG
AAATCAGGCACTTTGCCGAGGGCTATCGTCCTCGATGGGCGAGATAG

Upstream 100 bases:

>100_bases
CACCGCACAGGCGCGCGAAGCACCTGATGCGCACCTGATGCGGGCATGGTCCGGTCGGGACGCCGCAGCGGGCGCGGAGA
AGAGGGGAGACCAGGCGAAC

Downstream 100 bases:

>100_bases
GTTGCATGCCGCGCTGCCGGTACTCGCCGGGCGCGACGCCGGTCCATTTCTTGAATGCGCGGTGGAAGGTGCTCAGCTCG
GAAAAGCCCAGCCTCAGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKLHQLRILLAVAQHGSIHEASRGLHISQPALSKAIAELERELGVTLLSRSVRGVSLTAYGMALVKRATVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAALRKRFPNVALRGFEQRPQQIQEGLREGRLDLGLISTNSGPGAGGLQWE
SLFSVPMRLAVRPGHPLRRVRRLRPLLDADWLVLDPLDDPGSPISSLMRLHRLEIPRRVVQSASNLLGLQLATKTDLISM
WSDFVFRGTGGPLRMDPGSLEVLAMEDELPDFNVYLVYRSMDLMTHVCAEFSKEIRHFAEGYRPRWAR

Sequences:

>Translated_308_residues
MKLHQLRILLAVAQHGSIHEASRGLHISQPALSKAIAELERELGVTLLSRSVRGVSLTAYGMALVKRATVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAALRKRFPNVALRGFEQRPQQIQEGLREGRLDLGLISTNSGPGAGGLQWE
SLFSVPMRLAVRPGHPLRRVRRLRPLLDADWLVLDPLDDPGSPISSLMRLHRLEIPRRVVQSASNLLGLQLATKTDLISM
WSDFVFRGTGGPLRMDPGSLEVLAMEDELPDFNVYLVYRSMDLMTHVCAEFSKEIRHFAEGYRPRWAR
>Mature_308_residues
MKLHQLRILLAVAQHGSIHEASRGLHISQPALSKAIAELERELGVTLLSRSVRGVSLTAYGMALVKRATVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAALRKRFPNVALRGFEQRPQQIQEGLREGRLDLGLISTNSGPGAGGLQWE
SLFSVPMRLAVRPGHPLRRVRRLRPLLDADWLVLDPLDDPGSPISSLMRLHRLEIPRRVVQSASNLLGLQLATKTDLISM
WSDFVFRGTGGPLRMDPGSLEVLAMEDELPDFNVYLVYRSMDLMTHVCAEFSKEIRHFAEGYRPRWAR

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=30.4347826086957, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081904, Length=239, Percent_Identity=27.6150627615063, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790399, Length=177, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789506, Length=240, Percent_Identity=24.1666666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=168, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788887, Length=230, Percent_Identity=29.5652173913043, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI145693105, Length=178, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789204, Length=186, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=34.7517730496454, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=181, Percent_Identity=31.4917127071823, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=189, Percent_Identity=27.5132275132275, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=170, Percent_Identity=31.1764705882353, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=185, Percent_Identity=27.027027027027, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34292; Mature: 34292

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHQLRILLAVAQHGSIHEASRGLHISQPALSKAIAELERELGVTLLSRSVRGVSLTAY
CCHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GMALVKRATVVEQELRHALEDIESIRGHAEAELNIGFTAVASSGPLPDAMAALRKRFPNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCHHHHHHHHHHCCCH
ALRGFEQRPQQIQEGLREGRLDLGLISTNSGPGAGGLQWESLFSVPMRLAVRPGHPLRRV
HHHCHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHH
RRLRPLLDADWLVLDPLDDPGSPISSLMRLHRLEIPRRVVQSASNLLGLQLATKTDLISM
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
WSDFVFRGTGGPLRMDPGSLEVLAMEDELPDFNVYLVYRSMDLMTHVCAEFSKEIRHFAE
HHHHHEECCCCCCEECCCCEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
GYRPRWAR
CCCCCCCC
>Mature Secondary Structure
MKLHQLRILLAVAQHGSIHEASRGLHISQPALSKAIAELERELGVTLLSRSVRGVSLTAY
CCHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GMALVKRATVVEQELRHALEDIESIRGHAEAELNIGFTAVASSGPLPDAMAALRKRFPNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCHHHHHHHHHHCCCH
ALRGFEQRPQQIQEGLREGRLDLGLISTNSGPGAGGLQWESLFSVPMRLAVRPGHPLRRV
HHHCHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHH
RRLRPLLDADWLVLDPLDDPGSPISSLMRLHRLEIPRRVVQSASNLLGLQLATKTDLISM
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
WSDFVFRGTGGPLRMDPGSLEVLAMEDELPDFNVYLVYRSMDLMTHVCAEFSKEIRHFAE
HHHHHEECCCCCCEECCCCEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
GYRPRWAR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]