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The map label for this gene is frc [H]

Identifier: 94313286

GI number: 94313286

Start: 957538

End: 958770

Strand: Direct

Name: frc [H]

Synonym: Rmet_4361

Alternate gene names: 94313286

Gene position: 957538-958770 (Clockwise)

Preceding gene: 94313285

Following gene: 94313287

Centisome position: 37.11

GC content: 65.61

Gene sequence:

>1233_bases
ATGAACAACAAGGCACTGGAAGGGGTCCGCATTCTGGACATGACGCATGTGCAGGCCGGCCCGTCGGCCACCCAGCTGAT
GGCCTGGCTGGGTGCCGATGTCATCAAGGTGGAACTGCCCGGTCGCGGCGACATCACGCGTAGCCAGCTGCGCGATGTTC
CGAACGCGGACAGCCTCTACTTTACGATGCTGAACTCGAACAAGCGCAGTCTGACGTTGAACATGAAGACGCCGGAAGGC
AAGGCGCTGCTTGAAGACCTGGTGCAGCGCTGCGACGTGCTGGTGGAGAACTTCGGGCCGGGCGTGCTGGATCGCGCCGG
GTTCGACTGGGACCGCCTGCAGTCGCTGAATCCGCGCCTGATCTACGCATCGATCAAAGGCTTCGGCCCCGGCCCGTACG
CCGATTGCAAGGCGTACGAGAACGTGGCGCAGTGCATGGGCGGCTCGGCCAGCACCACTGGCAACGAAGACGGCGTGCCG
ACGGTGACCGGCGCGCAGATCGGCGATTCGGGCACGGGCGTGCATTGCGTGGTCGGCATCCTGGCCGCGCTGCTGCACCG
CGAGCAGAGCGGGCGTGGGCAGCGGGTGGAAGTCGCCATGCAGGACTCGGTGCTGAACCTGTGCCGCGTGAAGCTGCGCG
ATCAGCAACGGTTGTCGGCCGGGCCGCTCAAGGAGTATCCGAACGACGATTTCCAGGACTACGTGCCGCGCGCTGGCAAT
GCGTCCGGTGGCGGACAACCGGGTGCGGCGCTGCGCTGCTCGCCCGGTGGCGCCAACGACTTCGTCTACGTCATCATCCA
GCCGCAGGGCTGGGAGCCGCTGATGCGCCTGTGCGGCCGCGAGGATCTGATCACGCATCCGCAGTTCGCCACGCCGGAGG
CTCGCCTCAAGTGCCTGGCCGAGTGCTTCTCGATCGTCGAGAAATGGACGCGGACCAAGAGCAAGTTCGAGGTGATGGCG
GCGCTTAATGACGTTGACGTGCCGTGTGGCCCGATCCTGTCGATGAAGGACCTGATCGAGGATCGCTCGCTCTACGAACG
TGGCTATATGGTCGAACTCGACCATCCGGAGCGCGGCAGGTACGTGCAGCTCGGCTGCCCGATCTCGCTGTCGGCATCGC
CGGTGGAAGTCGAGCGCTCGCCGCTGCTTGGCGAGCATACCGAAGAGATCCTCGAGTGGCTCGGCCGCACGCCGTCGCAA
ATCGTCGCGCTCAAGGCCGCCGGCGCGGTGTAG

Upstream 100 bases:

>100_bases
GCGCGAGTACGCGCCGGGCACAAAGAACCAGACCATGTACAAGTAAAGGCCGGTCGCCAGCACGACATTGCCTCAAGAGA
ATCCTCAAGGAGACAACGCC

Downstream 100 bases:

>100_bases
CCCTCCACACCCTCAACGCACACTCTCTCAACCGATTCCGGCGAAATCCGCAGGCCGCCCGCATCTCCAATGCGTGGCGG
GTGGGCCTGCTTTCGCCCTG

Product: formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNNKALEGVRILDMTHVQAGPSATQLMAWLGADVIKVELPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTPEG
KALLEDLVQRCDVLVENFGPGVLDRAGFDWDRLQSLNPRLIYASIKGFGPGPYADCKAYENVAQCMGGSASTTGNEDGVP
TVTGAQIGDSGTGVHCVVGILAALLHREQSGRGQRVEVAMQDSVLNLCRVKLRDQQRLSAGPLKEYPNDDFQDYVPRAGN
ASGGGQPGAALRCSPGGANDFVYVIIQPQGWEPLMRLCGREDLITHPQFATPEARLKCLAECFSIVEKWTRTKSKFEVMA
ALNDVDVPCGPILSMKDLIEDRSLYERGYMVELDHPERGRYVQLGCPISLSASPVEVERSPLLGEHTEEILEWLGRTPSQ
IVALKAAGAV

Sequences:

>Translated_410_residues
MNNKALEGVRILDMTHVQAGPSATQLMAWLGADVIKVELPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTPEG
KALLEDLVQRCDVLVENFGPGVLDRAGFDWDRLQSLNPRLIYASIKGFGPGPYADCKAYENVAQCMGGSASTTGNEDGVP
TVTGAQIGDSGTGVHCVVGILAALLHREQSGRGQRVEVAMQDSVLNLCRVKLRDQQRLSAGPLKEYPNDDFQDYVPRAGN
ASGGGQPGAALRCSPGGANDFVYVIIQPQGWEPLMRLCGREDLITHPQFATPEARLKCLAECFSIVEKWTRTKSKFEVMA
ALNDVDVPCGPILSMKDLIEDRSLYERGYMVELDHPERGRYVQLGCPISLSASPVEVERSPLLGEHTEEILEWLGRTPSQ
IVALKAAGAV
>Mature_410_residues
MNNKALEGVRILDMTHVQAGPSATQLMAWLGADVIKVELPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTPEG
KALLEDLVQRCDVLVENFGPGVLDRAGFDWDRLQSLNPRLIYASIKGFGPGPYADCKAYENVAQCMGGSASTTGNEDGVP
TVTGAQIGDSGTGVHCVVGILAALLHREQSGRGQRVEVAMQDSVLNLCRVKLRDQQRLSAGPLKEYPNDDFQDYVPRAGN
ASGGGQPGAALRCSPGGANDFVYVIIQPQGWEPLMRLCGREDLITHPQFATPEARLKCLAECFSIVEKWTRTKSKFEVMA
ALNDVDVPCGPILSMKDLIEDRSLYERGYMVELDHPERGRYVQLGCPISLSASPVEVERSPLLGEHTEEILEWLGRTPSQ
IVALKAAGAV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=417, Percent_Identity=30.6954436450839, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI300863124, Length=443, Percent_Identity=28.8939051918736, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI266456254, Length=412, Percent_Identity=29.8543689320388, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI42794625, Length=412, Percent_Identity=29.8543689320388, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI300863126, Length=158, Percent_Identity=43.6708860759494, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI13376042, Length=443, Percent_Identity=26.1851015801354, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI266458397, Length=278, Percent_Identity=31.294964028777, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI266458393, Length=291, Percent_Identity=30.9278350515464, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI42822893, Length=190, Percent_Identity=30, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI266458395, Length=126, Percent_Identity=37.3015873015873, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788717, Length=412, Percent_Identity=53.3980582524272, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87082093, Length=402, Percent_Identity=32.3383084577114, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786222, Length=349, Percent_Identity=24.6418338108883, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648431, Length=410, Percent_Identity=32.6829268292683, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24585488, Length=197, Percent_Identity=30.9644670050761, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44652; Mature: 44652

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKALEGVRILDMTHVQAGPSATQLMAWLGADVIKVELPGRGDITRSQLRDVPNADSLY
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCCCEE
FTMLNSNKRSLTLNMKTPEGKALLEDLVQRCDVLVENFGPGVLDRAGFDWDRLQSLNPRL
EEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHCCCCEE
IYASIKGFGPGPYADCKAYENVAQCMGGSASTTGNEDGVPTVTGAQIGDSGTGVHCVVGI
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHH
LAALLHREQSGRGQRVEVAMQDSVLNLCRVKLRDQQRLSAGPLKEYPNDDFQDYVPRAGN
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
ASGGGQPGAALRCSPGGANDFVYVIIQPQGWEPLMRLCGREDLITHPQFATPEARLKCLA
CCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ECFSIVEKWTRTKSKFEVMAALNDVDVPCGPILSMKDLIEDRSLYERGYMVELDHPERGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCC
YVQLGCPISLSASPVEVERSPLLGEHTEEILEWLGRTPSQIVALKAAGAV
EEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECCCCC
>Mature Secondary Structure
MNNKALEGVRILDMTHVQAGPSATQLMAWLGADVIKVELPGRGDITRSQLRDVPNADSLY
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCCCEE
FTMLNSNKRSLTLNMKTPEGKALLEDLVQRCDVLVENFGPGVLDRAGFDWDRLQSLNPRL
EEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHCCCCEE
IYASIKGFGPGPYADCKAYENVAQCMGGSASTTGNEDGVPTVTGAQIGDSGTGVHCVVGI
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHH
LAALLHREQSGRGQRVEVAMQDSVLNLCRVKLRDQQRLSAGPLKEYPNDDFQDYVPRAGN
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
ASGGGQPGAALRCSPGGANDFVYVIIQPQGWEPLMRLCGREDLITHPQFATPEARLKCLA
CCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ECFSIVEKWTRTKSKFEVMAALNDVDVPCGPILSMKDLIEDRSLYERGYMVELDHPERGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCC
YVQLGCPISLSASPVEVERSPLLGEHTEEILEWLGRTPSQIVALKAAGAV
EEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]