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The map label for this gene is dgdR [H]

Identifier: 94313146

GI number: 94313146

Start: 803256

End: 804107

Strand: Direct

Name: dgdR [H]

Synonym: Rmet_4219

Alternate gene names: 94313146

Gene position: 803256-804107 (Clockwise)

Preceding gene: 94313144

Following gene: 94313147

Centisome position: 31.13

GC content: 66.55

Gene sequence:

>852_bases
ATGAAGAAGCTCGATCTCGATGTGATGGAGATGATCGTTGCCGTGGCCGATGCCGGGTCGTTCGCGCGCGCGGCGGAGAC
CCTGCATCGCTCGCCATCGGCCGTGAGCATGCAGATCAAGGCGATCGAGGACGTGCTCGGCAAGCCACTCTTCACGCGCA
CCACGCGCAACGTCGCCCTGACCGAGGACGGCAGGACGCTCCTGGATTACGGACGGCGAATGCTGGCGTTGCGGGAGGAG
GCATGGTCGGTGGTGGTTCGCCCGGAGATTCGCGGGCGCGTCACGATCGGCGTTCCCGACGATTACGCGTCGTCGCTGCT
GCCTTCGGTCCTGCGCCGATTCGCGGCGGCTCATCCGCGCGTGGAGATCCGTGTCATCGGGCTGCCCAGCCACGCGCTGA
TTCCATTGCTGAAGGACAACACGCTGGATCTGGCCTGCATCACGAAGGCGCGCGGCGTCACCGGGGATTTCATCCGCCAT
GAGCCGATGGTTTGGGTCTCGGCCCGCGGTGGCCGACCCATCTGGCGGGAGCGCCCGCTCCCGATCGCCGTCTTCGCCCA
CGGCAGTGCCGCGAGAGCCGGCGCCATCGCAGCGCTGCAGCAGGCCGATATTCAGTATCGGATGTCGTATGAAAGCCCCA
GTCTGCTTGGATTGATCAGCATGGTCGAGGCTGGACTGGCGGTAGCGCCGCTGGCGCGATGCAGCGTACCGGCGCATCTC
GCCGTGCTGGGGGAGTCCGAAGGACTGCCGCCGCTTGCGCCGCTGGAGGTCGTGCTGGCGCGTAGCGCGAAATCGGCGCG
GCTACCGTGCGACTTTCTGGCGGAGCAGATGCTGGCGGACTTGAAGGTCTGA

Upstream 100 bases:

>100_bases
TCCAGAACCATCCTTGATCGGGAATGCTGGCAGTATCGGACCACGGGATAACTAAGTAAAACGGATTATACTGATCCGAT
TGTTCAGATTTTCTGATGAA

Downstream 100 bases:

>100_bases
GGTCCCGACTGGCTGACGCCCGGCGTGATCAGATGATGGGGCAGCGAAGAGCAGGGATAAGGGCGAAACTCACATACGCG
AATCGAGGCGATTTTTTCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKKLDLDVMEMIVAVADAGSFARAAETLHRSPSAVSMQIKAIEDVLGKPLFTRTTRNVALTEDGRTLLDYGRRMLALREE
AWSVVVRPEIRGRVTIGVPDDYASSLLPSVLRRFAAAHPRVEIRVIGLPSHALIPLLKDNTLDLACITKARGVTGDFIRH
EPMVWVSARGGRPIWRERPLPIAVFAHGSAARAGAIAALQQADIQYRMSYESPSLLGLISMVEAGLAVAPLARCSVPAHL
AVLGESEGLPPLAPLEVVLARSAKSARLPCDFLAEQMLADLKV

Sequences:

>Translated_283_residues
MKKLDLDVMEMIVAVADAGSFARAAETLHRSPSAVSMQIKAIEDVLGKPLFTRTTRNVALTEDGRTLLDYGRRMLALREE
AWSVVVRPEIRGRVTIGVPDDYASSLLPSVLRRFAAAHPRVEIRVIGLPSHALIPLLKDNTLDLACITKARGVTGDFIRH
EPMVWVSARGGRPIWRERPLPIAVFAHGSAARAGAIAALQQADIQYRMSYESPSLLGLISMVEAGLAVAPLARCSVPAHL
AVLGESEGLPPLAPLEVVLARSAKSARLPCDFLAEQMLADLKV
>Mature_283_residues
MKKLDLDVMEMIVAVADAGSFARAAETLHRSPSAVSMQIKAIEDVLGKPLFTRTTRNVALTEDGRTLLDYGRRMLALREE
AWSVVVRPEIRGRVTIGVPDDYASSLLPSVLRRFAAAHPRVEIRVIGLPSHALIPLLKDNTLDLACITKARGVTGDFIRH
EPMVWVSARGGRPIWRERPLPIAVFAHGSAARAGAIAALQQADIQYRMSYESPSLLGLISMVEAGLAVAPLARCSVPAHL
AVLGESEGLPPLAPLEVVLARSAKSARLPCDFLAEQMLADLKV

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=264, Percent_Identity=32.9545454545455, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787806, Length=261, Percent_Identity=27.5862068965517, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790208, Length=124, Percent_Identity=35.4838709677419, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=26.9076305220884, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=126, Percent_Identity=34.1269841269841, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=138, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994962, Length=150, Percent_Identity=28.6666666666667, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693193, Length=122, Percent_Identity=33.6065573770492, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788887, Length=130, Percent_Identity=36.9230769230769, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=155, Percent_Identity=30.9677419354839, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30631; Mature: 30631

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLDLDVMEMIVAVADAGSFARAAETLHRSPSAVSMQIKAIEDVLGKPLFTRTTRNVAL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCEEECCCCEEE
TEDGRTLLDYGRRMLALREEAWSVVVRPEIRGRVTIGVPDDYASSLLPSVLRRFAAAHPR
ECCCCHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCC
VEIRVIGLPSHALIPLLKDNTLDLACITKARGVTGDFIRHEPMVWVSARGGRPIWRERPL
EEEEEEECCCHHEEEEECCCCEEEEEEHHCCCCCCHHHCCCCEEEEECCCCCCCCCCCCC
PIAVFAHGSAARAGAIAALQQADIQYRMSYESPSLLGLISMVEAGLAVAPLARCSVPAHL
CEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEE
AVLGESEGLPPLAPLEVVLARSAKSARLPCDFLAEQMLADLKV
EEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLDLDVMEMIVAVADAGSFARAAETLHRSPSAVSMQIKAIEDVLGKPLFTRTTRNVAL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCEEECCCCEEE
TEDGRTLLDYGRRMLALREEAWSVVVRPEIRGRVTIGVPDDYASSLLPSVLRRFAAAHPR
ECCCCHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCC
VEIRVIGLPSHALIPLLKDNTLDLACITKARGVTGDFIRHEPMVWVSARGGRPIWRERPL
EEEEEEECCCHHEEEEECCCCEEEEEEHHCCCCCCHHHCCCCEEEEECCCCCCCCCCCCC
PIAVFAHGSAARAGAIAALQQADIQYRMSYESPSLLGLISMVEAGLAVAPLARCSVPAHL
CEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEE
AVLGESEGLPPLAPLEVVLARSAKSARLPCDFLAEQMLADLKV
EEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]