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The map label for this gene is nahD [H]

Identifier: 94313123

GI number: 94313123

Start: 781579

End: 782172

Strand: Reverse

Name: nahD [H]

Synonym: Rmet_4196

Alternate gene names: 94313123

Gene position: 782172-781579 (Counterclockwise)

Preceding gene: 94313124

Following gene: 94313121

Centisome position: 30.32

GC content: 63.64

Gene sequence:

>594_bases
ATGAACAAGCAGGTGGAATTTTTCTTCGATTTCGGCAGCCCCTACTCGTACCTGGCGTACAAGGAACTGCCTCGCGTGGC
GGCGCGTACCGGCGCAACGATCATGTGGCGGCCGATGCTGCTGGGCGGGGTGTTCAAGGCCACCGGCAACCATAGCCCGG
CCGAGATTCCGGCCAAGAGCAAGTGGTCGTCCGGCGATACCGAACGCTGGGCCCGGCGCTACGATGCACCGTTCCGGCAC
AACCCGTTCTTTCCGGTGAACACGCTGGCCCTGATGCGTGGCGCGATCGGCTACCAGCGCAAGGGTGACGCCGAGTTCCA
CCGCTATGTCGACGCGATCTTCAGCGCGATGTGGGAACACGGCAAGAACCTCAACGACCCGAACGAGATCGGCAAGGTGC
TGGTGGCGGCGGGATTCGACCCGCGCGAGGCACTGGCGATGCTCGACGACCCCGAGGTCAAGGCCGAACTCAAGCAGGTG
ACCGAGGAAGCCGTGGCACGCGGCATCTTCGGCGCGCCAAGCTTCATTGTCGATGGCGAATTGTTCTGGGGCAACGACCG
GCTGACGTTCGTCGAGGAACAGCTCGCCGGCTAA

Upstream 100 bases:

>100_bases
CGATCTGCGTCCCTGGATCGAACACTGGTAATCGCCCTCAAGCCAGCATTGCCAAGAAGCACAAAGCCGGACGCAAAGCC
GGACACAAAGGAGACATGCA

Downstream 100 bases:

>100_bases
TGCCACCCGCCCGGGTAAATCCCCCTCGGGCGGGCCTTCAGACGAACCATCAAGCCGCCAGCTTGAACGTTGTCACGGCG
GCGGCAAGCTGGTTGGCATG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MNKQVEFFFDFGSPYSYLAYKELPRVAARTGATIMWRPMLLGGVFKATGNHSPAEIPAKSKWSSGDTERWARRYDAPFRH
NPFFPVNTLALMRGAIGYQRKGDAEFHRYVDAIFSAMWEHGKNLNDPNEIGKVLVAAGFDPREALAMLDDPEVKAELKQV
TEEAVARGIFGAPSFIVDGELFWGNDRLTFVEEQLAG

Sequences:

>Translated_197_residues
MNKQVEFFFDFGSPYSYLAYKELPRVAARTGATIMWRPMLLGGVFKATGNHSPAEIPAKSKWSSGDTERWARRYDAPFRH
NPFFPVNTLALMRGAIGYQRKGDAEFHRYVDAIFSAMWEHGKNLNDPNEIGKVLVAAGFDPREALAMLDDPEVKAELKQV
TEEAVARGIFGAPSFIVDGELFWGNDRLTFVEEQLAG
>Mature_197_residues
MNKQVEFFFDFGSPYSYLAYKELPRVAARTGATIMWRPMLLGGVFKATGNHSPAEIPAKSKWSSGDTERWARRYDAPFRH
NPFFPVNTLALMRGAIGYQRKGDAEFHRYVDAIFSAMWEHGKNLNDPNEIGKVLVAAGFDPREALAMLDDPEVKAELKQV
TEEAVARGIFGAPSFIVDGELFWGNDRLTFVEEQLAG

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705704, Length=209, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI219842333, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538137, Length=204, Percent_Identity=26.9607843137255, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539520, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22152; Mature: 22152

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQVEFFFDFGSPYSYLAYKELPRVAARTGATIMWRPMLLGGVFKATGNHSPAEIPAKS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
KWSSGDTERWARRYDAPFRHNPFFPVNTLALMRGAIGYQRKGDAEFHRYVDAIFSAMWEH
CCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GKNLNDPNEIGKVLVAAGFDPREALAMLDDPEVKAELKQVTEEAVARGIFGAPSFIVDGE
CCCCCCHHHHHHEHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCE
LFWGNDRLTFVEEQLAG
EEECCCCEEEHHHHHCC
>Mature Secondary Structure
MNKQVEFFFDFGSPYSYLAYKELPRVAARTGATIMWRPMLLGGVFKATGNHSPAEIPAKS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
KWSSGDTERWARRYDAPFRHNPFFPVNTLALMRGAIGYQRKGDAEFHRYVDAIFSAMWEH
CCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GKNLNDPNEIGKVLVAAGFDPREALAMLDDPEVKAELKQVTEEAVARGIFGAPSFIVDGE
CCCCCCHHHHHHEHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCE
LFWGNDRLTFVEEQLAG
EEECCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]