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The map label for this gene is tauD [H]

Identifier: 94313063

GI number: 94313063

Start: 710349

End: 711275

Strand: Direct

Name: tauD [H]

Synonym: Rmet_4136

Alternate gene names: 94313063

Gene position: 710349-711275 (Clockwise)

Preceding gene: 291481515

Following gene: 94313064

Centisome position: 27.53

GC content: 64.51

Gene sequence:

>927_bases
ATGACGATTGCCACTGCCGACGCTTCCGTCGATACCTCCGCCAACCTCGCCACCGAGTCTTCCACCAGATCCCTTCAGGA
TTTCGAGATCCGCCCGCTGGGCGCCGCACTGGGTGCGGAAGTCATCGGGGTCGATCTGGGGCGGCCGCTGTCGCATGGTG
ATTTCCAGCGCATCCATCAGGCGCATCTCGATCATCACGTGCTGGTGTTCCGCGACCAGCGCATCACGCCGGCACAACAG
ATCGCCTTCAGCCGCCGCTTCGGGCCGCTGCAGATTCACGTGCTGAACCAGTTCCAGTTGCCGGGCCACCCCGAAGTGCT
GATCGTCTCGAACGTGATCGAGAACGGCAAGCCGATCGGGCTGGGTGATGCCGGCCACTTCTGGCATTCGGATCTCTCGT
ACAAGGAGACACCGAGTCTTGGTTCCCTGTTGCACGCACGGGAGTTGCCCGCCGAAGGCGGCGACACGCTTTTCGCCAAT
ATGCACACCGCATGGGAGAGCCTGCCGGAAGCGCTGCAGCGCAAGGTGGCGGATCTCACCGCCGAGCACACGTATCTGGC
GCGGTACGCCGAGTTGCAGGCGCGCAGCCCGTGGCGTCCGAACCTGACGCCGGAGCAGATCGCGCAGGTCAAGCCCGTGG
TGCATCCGGTGGTCCGCACGCATCCGGAGACCGGGCGTCGCGCGCTGTTCGTCAGCGAGCATTTCACCACGCGCATCGTC
GGCCTGCCTGATGCCGAAAGCCGCGCGATCCTCGATGAATTGTTTGCGCACAGCGTGAAGCCCGAGCACGTGTACCGCCA
TCAGTGGCGCGAGCACGACCTCGTGTTCTGGGACAACCGGTCGCTGCTGCATCTGGCCGCCGGCACGCCCGATCAACTGC
GGCGCGTGATGTATCGCACCACGATCGAAGGCGATCAGCCGTTCTGA

Upstream 100 bases:

>100_bases
TAAGGAATCCGCATAATCGCGCGCGATTTGATTCGTTGTCCGGCCGGTGCGGCTTCCCTACAGTGCAAGGCTTGTGCTTC
CCCCAGAGCAAAGACCTGCC

Downstream 100 bases:

>100_bases
TTCGATTCTCGTTTTTTCACTCCGGCCCCATTTTTCAGGAGTCCATTGCATGTCGCTGTTTTCGTCCGCTTCCACCCTGA
CCCGTCGCGCCGCCGTTGCC

Product: taurine dioxygenase (TauD/TfdA family)

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTIATADASVDTSANLATESSTRSLQDFEIRPLGAALGAEVIGVDLGRPLSHGDFQRIHQAHLDHHVLVFRDQRITPAQQ
IAFSRRFGPLQIHVLNQFQLPGHPEVLIVSNVIENGKPIGLGDAGHFWHSDLSYKETPSLGSLLHARELPAEGGDTLFAN
MHTAWESLPEALQRKVADLTAEHTYLARYAELQARSPWRPNLTPEQIAQVKPVVHPVVRTHPETGRRALFVSEHFTTRIV
GLPDAESRAILDELFAHSVKPEHVYRHQWREHDLVFWDNRSLLHLAAGTPDQLRRVMYRTTIEGDQPF

Sequences:

>Translated_308_residues
MTIATADASVDTSANLATESSTRSLQDFEIRPLGAALGAEVIGVDLGRPLSHGDFQRIHQAHLDHHVLVFRDQRITPAQQ
IAFSRRFGPLQIHVLNQFQLPGHPEVLIVSNVIENGKPIGLGDAGHFWHSDLSYKETPSLGSLLHARELPAEGGDTLFAN
MHTAWESLPEALQRKVADLTAEHTYLARYAELQARSPWRPNLTPEQIAQVKPVVHPVVRTHPETGRRALFVSEHFTTRIV
GLPDAESRAILDELFAHSVKPEHVYRHQWREHDLVFWDNRSLLHLAAGTPDQLRRVMYRTTIEGDQPF
>Mature_307_residues
TIATADASVDTSANLATESSTRSLQDFEIRPLGAALGAEVIGVDLGRPLSHGDFQRIHQAHLDHHVLVFRDQRITPAQQI
AFSRRFGPLQIHVLNQFQLPGHPEVLIVSNVIENGKPIGLGDAGHFWHSDLSYKETPSLGSLLHARELPAEGGDTLFANM
HTAWESLPEALQRKVADLTAEHTYLARYAELQARSPWRPNLTPEQIAQVKPVVHPVVRTHPETGRRALFVSEHFTTRIVG
LPDAESRAILDELFAHSVKPEHVYRHQWREHDLVFWDNRSLLHLAAGTPDQLRRVMYRTTIEGDQPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=291, Percent_Identity=41.2371134020619, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322971, Length=316, Percent_Identity=26.8987341772152, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 34624; Mature: 34493

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIATADASVDTSANLATESSTRSLQDFEIRPLGAALGAEVIGVDLGRPLSHGDFQRIHQ
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCHHHHHHHH
AHLDHHVLVFRDQRITPAQQIAFSRRFGPLQIHVLNQFQLPGHPEVLIVSNVIENGKPIG
HHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEHHHHCCCCCC
LGDAGHFWHSDLSYKETPSLGSLLHARELPAEGGDTLFANMHTAWESLPEALQRKVADLT
CCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
AEHTYLARYAELQARSPWRPNLTPEQIAQVKPVVHPVVRTHPETGRRALFVSEHFTTRIV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEE
GLPDAESRAILDELFAHSVKPEHVYRHQWREHDLVFWDNRSLLHLAAGTPDQLRRVMYRT
ECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHHHHH
TIEGDQPF
HCCCCCCC
>Mature Secondary Structure 
TIATADASVDTSANLATESSTRSLQDFEIRPLGAALGAEVIGVDLGRPLSHGDFQRIHQ
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCHHHHHHHH
AHLDHHVLVFRDQRITPAQQIAFSRRFGPLQIHVLNQFQLPGHPEVLIVSNVIENGKPIG
HHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEHHHHCCCCCC
LGDAGHFWHSDLSYKETPSLGSLLHARELPAEGGDTLFANMHTAWESLPEALQRKVADLT
CCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
AEHTYLARYAELQARSPWRPNLTPEQIAQVKPVVHPVVRTHPETGRRALFVSEHFTTRIV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEE
GLPDAESRAILDELFAHSVKPEHVYRHQWREHDLVFWDNRSLLHLAAGTPDQLRRVMYRT
ECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHHHHH
TIEGDQPF
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]