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The map label for this gene is ahpC [C]

Identifier: 94313058

GI number: 94313058

Start: 705457

End: 706110

Strand: Reverse

Name: ahpC [C]

Synonym: Rmet_4131

Alternate gene names: 94313058

Gene position: 706110-705457 (Counterclockwise)

Preceding gene: 94313059

Following gene: 94313054

Centisome position: 27.37

GC content: 60.4

Gene sequence:

>654_bases
ATGGCAATCCGACTTGGCGAGGAAGCACCGGACTTCACCGCCGACACCACTGAAGGGAAGATTCATTTTCATGAGTGGAT
CGGCGACAGCTGGGCCATCCTTTTCTCGCACCCCAAGGATTTCACGCCGGTCTGCACCACCGAGCTCGGCTACATGGCCA
AGCTGAAGCCCGAGTTCGACAAACGCAATACGAAGATCATCGGCCTGTCGATCGATCCGGTGGGCGACCATTCGCGCTGG
GTCAAGGACATCGAGGAAACGCAGGGCGCCACGGTCAACTACCCGATGATCGGCGATCACGACCTCAAGGTGGCCAAGCT
CTACGACATGATCCACCCCGAGGCGAGCGGCGGCCCACGCACGGCAGCGGACAACGCCACGATCCGCGCGGTGTTCATGA
TCGGCCCTGACAAGAAGGTCAAGGCCATGCTGGTCTACCCGATGAGCGCGGGACGCAATTTCGACGAGGTGCTGCGCCTG
CTCGACTCGCTGCAACTGAACGCGAAACACACCGTCGCCACACCCGTCAACTGGAAGCCGGGCGACGACGTGATCATCCC
CACCTCGGTGTCGGATGACGACGCGAAGAAGAAATATCCACAGGGCTTCAAGACGCTCAAGCCTTATCTGCGAACGGTTG
CCCAGCCGAAGTAG

Upstream 100 bases:

>100_bases
ATTGTCCGTCCGGCGGGCAAACCAGTTCCTATACTGGATTTTCGCCGCACAGACGGCTGCGTCACGCCCCCACCCAACCC
ACCAATAAAGGAGCACGACC

Downstream 100 bases:

>100_bases
GGACCGAAGTAAGCACCTCTGTTAATACAGATGGGGTAGTCCGCACGACGGATAGGAACTATCCACAGAGAGCGTGGATA
ATCCCCCTCTTGACAACCCG

Product: 1-Cysteine peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAIRLGEEAPDFTADTTEGKIHFHEWIGDSWAILFSHPKDFTPVCTTELGYMAKLKPEFDKRNTKIIGLSIDPVGDHSRW
VKDIEETQGATVNYPMIGDHDLKVAKLYDMIHPEASGGPRTAADNATIRAVFMIGPDKKVKAMLVYPMSAGRNFDEVLRL
LDSLQLNAKHTVATPVNWKPGDDVIIPTSVSDDDAKKKYPQGFKTLKPYLRTVAQPK

Sequences:

>Translated_217_residues
MAIRLGEEAPDFTADTTEGKIHFHEWIGDSWAILFSHPKDFTPVCTTELGYMAKLKPEFDKRNTKIIGLSIDPVGDHSRW
VKDIEETQGATVNYPMIGDHDLKVAKLYDMIHPEASGGPRTAADNATIRAVFMIGPDKKVKAMLVYPMSAGRNFDEVLRL
LDSLQLNAKHTVATPVNWKPGDDVIIPTSVSDDDAKKKYPQGFKTLKPYLRTVAQPK
>Mature_216_residues
AIRLGEEAPDFTADTTEGKIHFHEWIGDSWAILFSHPKDFTPVCTTELGYMAKLKPEFDKRNTKIIGLSIDPVGDHSRWV
KDIEETQGATVNYPMIGDHDLKVAKLYDMIHPEASGGPRTAADNATIRAVFMIGPDKKVKAMLVYPMSAGRNFDEVLRLL
DSLQLNAKHTVATPVNWKPGDDVIIPTSVSDDDAKKKYPQGFKTLKPYLRTVAQPK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=227, Percent_Identity=49.7797356828194, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI32189392, Length=203, Percent_Identity=27.0935960591133, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI5453549, Length=170, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483377, Length=195, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI5802974, Length=195, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1786822, Length=159, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25153706, Length=226, Percent_Identity=39.8230088495575, Blast_Score=163, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=200, Percent_Identity=27, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32565831, Length=200, Percent_Identity=27, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554494, Length=158, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=53.7735849056604, Blast_Score=236, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6323613, Length=205, Percent_Identity=23.9024390243902, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652436, Length=205, Percent_Identity=50.2439024390244, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24652434, Length=205, Percent_Identity=49.2682926829268, Blast_Score=198, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=49.2682926829268, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24581278, Length=224, Percent_Identity=44.1964285714286, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17738015, Length=205, Percent_Identity=27.8048780487805, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=31.1764705882353, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=31.1764705882353, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357347, Length=201, Percent_Identity=25.3731343283582, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24656348, Length=169, Percent_Identity=29.585798816568, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17864676, Length=169, Percent_Identity=29.585798816568, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24207; Mature: 24076

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRLGEEAPDFTADTTEGKIHFHEWIGDSWAILFSHPKDFTPVCTTELGYMAKLKPEFD
CEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCCC
KRNTKIIGLSIDPVGDHSRWVKDIEETQGATVNYPMIGDHDLKVAKLYDMIHPEASGGPR
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
TAADNATIRAVFMIGPDKKVKAMLVYPMSAGRNFDEVLRLLDSLQLNAKHTVATPVNWKP
CCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
GDDVIIPTSVSDDDAKKKYPQGFKTLKPYLRTVAQPK
CCCEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIRLGEEAPDFTADTTEGKIHFHEWIGDSWAILFSHPKDFTPVCTTELGYMAKLKPEFD
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCCC
KRNTKIIGLSIDPVGDHSRWVKDIEETQGATVNYPMIGDHDLKVAKLYDMIHPEASGGPR
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
TAADNATIRAVFMIGPDKKVKAMLVYPMSAGRNFDEVLRLLDSLQLNAKHTVATPVNWKP
CCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
GDDVIIPTSVSDDDAKKKYPQGFKTLKPYLRTVAQPK
CCCEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]