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The map label for this gene is gstA [H]

Identifier: 94312979

GI number: 94312979

Start: 617587

End: 618258

Strand: Reverse

Name: gstA [H]

Synonym: Rmet_4051

Alternate gene names: 94312979

Gene position: 618258-617587 (Counterclockwise)

Preceding gene: 94312980

Following gene: 94312978

Centisome position: 23.96

GC content: 65.18

Gene sequence:

>672_bases
TTGATGCGAGCCCGGCATTTGCCGTCGCGCCGAACCATCGCATCCAAGGACGTCCCGACCATGAAACTCTATGTGCACCC
GCTTTCCGGCCACGCCCACCGCGCACAGCTGCTCCTGTCCCTGCTCGGCCAGCCGGCAGAACTGATCGAAGTGGACCTGA
TGACCGGCGCGCACAAATCGCCCGAGTTCCTGAAGCTGAATCCGTTCGGCCAGATCCCGGTGCTGGTCGATGGCGAAACG
GTCGTGCCCGATTCGAACGCGATCCTGGTCTACCTGAGCAAGAAGCTTGGCCGCACCGACTGGCTGCCCGAAGCACCGGC
GACGGCAGCGGCTGTGCAACGCTGGCTGTCGGTCGCCGCAGGCGACATTGCCTTCGGACCTGCCCGCGCTCGCATCGCCA
CGCTGTTCAACGCGCCGTACGATCTGGATGATGCTGTCGCGCGGGCCCACGTCGTGCTCAAGCGCATGGACGATGCGCTG
GCCGATCGTCCATGGATCGCCGCCGATCATCCAACGATTGCAGACGTGGCGCTCTACAGCTACACCGCGCGGGCGCCGGA
GGGCTTTGTCGATCTGCGGGACTACGGCAAAGTGCGCCAATGGCTGGCTCGCGTGGAGGCCCTGCCGGGCTTCGTGCCGA
TTGTGAAAAGCCCGGTCGGACTCGAAGCCTGA

Upstream 100 bases:

>100_bases
GTAGGACGCCCCATCGTCGGGTTCTCCGCGGATTCTTCTCGAATCCGCAAGAGTCACTTCTTCCCCCGGCCGTTTTTCGT
GGCACGGGACGCCCCTATAT

Downstream 100 bases:

>100_bases
ATCCGCCTGCCTGCCTGAAATCGCCTGTCCGAGAAGTCGCCACCTGGAGCGCGCCATGAACCGTCAACCTGCCCCCCATG
CGGAGCTGCTGCCCGGCACG

Product: putative glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MMRARHLPSRRTIASKDVPTMKLYVHPLSGHAHRAQLLLSLLGQPAELIEVDLMTGAHKSPEFLKLNPFGQIPVLVDGET
VVPDSNAILVYLSKKLGRTDWLPEAPATAAAVQRWLSVAAGDIAFGPARARIATLFNAPYDLDDAVARAHVVLKRMDDAL
ADRPWIAADHPTIADVALYSYTARAPEGFVDLRDYGKVRQWLARVEALPGFVPIVKSPVGLEA

Sequences:

>Translated_223_residues
MMRARHLPSRRTIASKDVPTMKLYVHPLSGHAHRAQLLLSLLGQPAELIEVDLMTGAHKSPEFLKLNPFGQIPVLVDGET
VVPDSNAILVYLSKKLGRTDWLPEAPATAAAVQRWLSVAAGDIAFGPARARIATLFNAPYDLDDAVARAHVVLKRMDDAL
ADRPWIAADHPTIADVALYSYTARAPEGFVDLRDYGKVRQWLARVEALPGFVPIVKSPVGLEA
>Mature_223_residues
MMRARHLPSRRTIASKDVPTMKLYVHPLSGHAHRAQLLLSLLGQPAELIEVDLMTGAHKSPEFLKLNPFGQIPVLVDGET
VVPDSNAILVYLSKKLGRTDWLPEAPATAAAVQRWLSVAAGDIAFGPARARIATLFNAPYDLDDAVARAHVVLKRMDDAL
ADRPWIAADHPTIADVALYSYTARAPEGFVDLRDYGKVRQWLARVEALPGFVPIVKSPVGLEA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=178, Percent_Identity=33.1460674157303, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI124249394, Length=178, Percent_Identity=33.1460674157303, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1788640, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922932, Length=196, Percent_Identity=31.1224489795918, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24654965, Length=180, Percent_Identity=31.6666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19922526, Length=202, Percent_Identity=33.1683168316832, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17864592, Length=182, Percent_Identity=28.021978021978, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654992, Length=184, Percent_Identity=32.0652173913043, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130115, Length=202, Percent_Identity=31.1881188118812, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85725204, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737923, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45549270, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864594, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221378983, Length=186, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17933730, Length=203, Percent_Identity=23.6453201970443, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922532, Length=184, Percent_Identity=30.9782608695652, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646259, Length=186, Percent_Identity=30.6451612903226, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130123, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 24366; Mature: 24366

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRARHLPSRRTIASKDVPTMKLYVHPLSGHAHRAQLLLSLLGQPAELIEVDLMTGAHKS
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEHHHCCCCCC
PEFLKLNPFGQIPVLVDGETVVPDSNAILVYLSKKLGRTDWLPEAPATAAAVQRWLSVAA
CCEEEECCCCCCCEEECCCEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
GDIAFGPARARIATLFNAPYDLDDAVARAHVVLKRMDDALADRPWIAADHPTIADVALYS
CCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
YTARAPEGFVDLRDYGKVRQWLARVEALPGFVPIVKSPVGLEA
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MMRARHLPSRRTIASKDVPTMKLYVHPLSGHAHRAQLLLSLLGQPAELIEVDLMTGAHKS
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEHHHCCCCCC
PEFLKLNPFGQIPVLVDGETVVPDSNAILVYLSKKLGRTDWLPEAPATAAAVQRWLSVAA
CCEEEECCCCCCCEEECCCEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
GDIAFGPARARIATLFNAPYDLDDAVARAHVVLKRMDDALADRPWIAADHPTIADVALYS
CCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
YTARAPEGFVDLRDYGKVRQWLARVEALPGFVPIVKSPVGLEA
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA