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The map label for this gene is nahR [H]

Identifier: 94312950

GI number: 94312950

Start: 592121

End: 593017

Strand: Direct

Name: nahR [H]

Synonym: Rmet_4022

Alternate gene names: 94312950

Gene position: 592121-593017 (Clockwise)

Preceding gene: 94312948

Following gene: 94312953

Centisome position: 22.95

GC content: 67.22

Gene sequence:

>897_bases
ATGATTAATTTGAGGCGTCTCGATCTGAACCTGCTCGTCACACTCGACACGCTGCTGGCCGAGCATAACGTCACGCGCGC
GGCCGAGCGGCTGCACTACTCCCAGCCCTCGGTGAGCGTGCATCTGGCCAGGCTGCGAGAGATCTTTGACGATCCGCTTT
TGCTGCCCGGGCCACGTGGCATGCGCCCCACCGCCCGCGCCGAATCACTGCGCGAACCGCTGCGCGAGGCGCTGGCCGCA
CTGGAGGCGGCCATCTCGCCAGAGCATCCGTTCGACCCCGCCGAGGCCACGCAGACATGGCGCGTTGCCGCCACCGACTA
CAGCGAAACAACCGTATTGCTGCCGGCGCTGGCCGGCTTGCGCCAGGCTGCGCCCGGCACCCGCATGGCGGTCATTGAAC
TGGCGCCGCCACGGATTGCGCGTCAGGCGGAGCAAGGTGACGTCGATCTGGTGTTCCATATCACCACCGATGCCCCGGAA
AGCCTGCATCTCCTTCCGCTGTTCACCGAGCGCTTCGTGCTGGCCGGCCGCCGTGGGCACCCACGCCTGAAGCGCAAGCC
GACCATCGCCCAGTTCTGCGCACTGGAGCATGTGATCGTGTCGCCCGAGGGCGGGGGATTCGTCGGTGCCACCGATGAGG
CGTTGGCCGAGGTGGGGCTGTCGCGACGGGTCGTGCTGTCCGTGCCGCACTTCCTCTACCTTGAATCGGTGCTGGCCAGC
ACCGATCTGGTCGCGATGCTGCCGGCCCGGCTGGTGCGGGACAACGACCGGCTGCAGATCGTCGATGCGCCAGTGGAGGT
GCCAGGATTCGAGATGTCGATGTTGTGGCACGAGCGGGTCCATCGCGACCCCGCGCATCAGTGGCTGCGGGAGTCGATCG
CGGCGGCGGTGCGATAG

Upstream 100 bases:

>100_bases
CGTTCATGTCGGTGTCCTGATGACTGAGGATGGGGCAGGACCAAGATTAGGTTCGCCTGAGTTATATTGGAAATGAATTC
CTAATATCCCAGGTATTGCC

Downstream 100 bases:

>100_bases
GTGGGGCCCGGATGGCTCCGGGCCCGTGATGGCGGTGTGATGGTGGTGTGATGGCGGCCGCCGGATGACAGTCAGATGTC
GTCGGGATGACGTTGGGATG

Product: putative LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MINLRRLDLNLLVTLDTLLAEHNVTRAAERLHYSQPSVSVHLARLREIFDDPLLLPGPRGMRPTARAESLREPLREALAA
LEAAISPEHPFDPAEATQTWRVAATDYSETTVLLPALAGLRQAAPGTRMAVIELAPPRIARQAEQGDVDLVFHITTDAPE
SLHLLPLFTERFVLAGRRGHPRLKRKPTIAQFCALEHVIVSPEGGGFVGATDEALAEVGLSRRVVLSVPHFLYLESVLAS
TDLVAMLPARLVRDNDRLQIVDAPVEVPGFEMSMLWHERVHRDPAHQWLRESIAAAVR

Sequences:

>Translated_298_residues
MINLRRLDLNLLVTLDTLLAEHNVTRAAERLHYSQPSVSVHLARLREIFDDPLLLPGPRGMRPTARAESLREPLREALAA
LEAAISPEHPFDPAEATQTWRVAATDYSETTVLLPALAGLRQAAPGTRMAVIELAPPRIARQAEQGDVDLVFHITTDAPE
SLHLLPLFTERFVLAGRRGHPRLKRKPTIAQFCALEHVIVSPEGGGFVGATDEALAEVGLSRRVVLSVPHFLYLESVLAS
TDLVAMLPARLVRDNDRLQIVDAPVEVPGFEMSMLWHERVHRDPAHQWLRESIAAAVR
>Mature_298_residues
MINLRRLDLNLLVTLDTLLAEHNVTRAAERLHYSQPSVSVHLARLREIFDDPLLLPGPRGMRPTARAESLREPLREALAA
LEAAISPEHPFDPAEATQTWRVAATDYSETTVLLPALAGLRQAAPGTRMAVIELAPPRIARQAEQGDVDLVFHITTDAPE
SLHLLPLFTERFVLAGRRGHPRLKRKPTIAQFCALEHVIVSPEGGGFVGATDEALAEVGLSRRVVLSVPHFLYLESVLAS
TDLVAMLPARLVRDNDRLQIVDAPVEVPGFEMSMLWHERVHRDPAHQWLRESIAAAVR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=26.4214046822742, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081766, Length=251, Percent_Identity=26.6932270916335, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786820, Length=277, Percent_Identity=25.6317689530686, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790147, Length=306, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33036; Mature: 33036

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLRRLDLNLLVTLDTLLAEHNVTRAAERLHYSQPSVSVHLARLREIFDDPLLLPGPRG
CCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
MRPTARAESLREPLREALAALEAAISPEHPFDPAEATQTWRVAATDYSETTVLLPALAGL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHH
RQAAPGTRMAVIELAPPRIARQAEQGDVDLVFHITTDAPESLHLLPLFTERFVLAGRRGH
HHCCCCCEEEEEEECCCHHHHHCCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCC
PRLKRKPTIAQFCALEHVIVSPEGGGFVGATDEALAEVGLSRRVVLSVPHFLYLESVLAS
CCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHH
TDLVAMLPARLVRDNDRLQIVDAPVEVPGFEMSMLWHERVHRDPAHQWLRESIAAAVR
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINLRRLDLNLLVTLDTLLAEHNVTRAAERLHYSQPSVSVHLARLREIFDDPLLLPGPRG
CCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
MRPTARAESLREPLREALAALEAAISPEHPFDPAEATQTWRVAATDYSETTVLLPALAGL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHH
RQAAPGTRMAVIELAPPRIARQAEQGDVDLVFHITTDAPESLHLLPLFTERFVLAGRRGH
HHCCCCCEEEEEEECCCHHHHHCCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCC
PRLKRKPTIAQFCALEHVIVSPEGGGFVGATDEALAEVGLSRRVVLSVPHFLYLESVLAS
CCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHH
TDLVAMLPARLVRDNDRLQIVDAPVEVPGFEMSMLWHERVHRDPAHQWLRESIAAAVR
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]