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The map label for this gene is fecR [H]

Identifier: 94312928

GI number: 94312928

Start: 571663

End: 572607

Strand: Reverse

Name: fecR [H]

Synonym: Rmet_4000

Alternate gene names: 94312928

Gene position: 572607-571663 (Counterclockwise)

Preceding gene: 94312929

Following gene: 94312927

Centisome position: 22.19

GC content: 69.31

Gene sequence:

>945_bases
GTGGCACTCGCCGCAGTGGAATGGTTGGTAACGCTGCAAGGCGGTGAAACGGATGGGGCATCCCACGCCGCGTGGCGCCA
TTGGCTCTCTCAGCATCCCGACCACGCGCGCGCCTGGGCGCGGATCGAGGCAGTGAATGCGCGGCTGCGCGACGTCGCGT
CGCCACTGACCACGGCCGTCGCGCACGCGGCGCTGACTACGCCGCGCTCCGCGAGTCGCCGCCGGGCCGTCCAGGCGCTG
GTGGTTGCCTTCACCGGCGGCGCGGCAGCATGGGCTGCGCGAGATCACGCGCCATTGCAGGACTGGCTGGCCGATGTAAG
TACGGCCGTGGGTGAGCAACGTCTTCTGTCGCTCGCGGACGGCACGCAGATCAGACTCAATTCCGATACCGCCATCGATA
TCGCCTTCACGGCCACCGAGCGGCGTGTTGTCCTGCGACGCGGCGAGATCCATGTCCAGACAGCCCCGGATCGACACTGG
CCAGCGCGCCCATTCATCGTCGCAACCGCCTCGGCCACGCTACGCCCAATGGGCACCCGGTTCGCGGTGCGCGTATCGGG
TGACGCCGGCTGGATCGCCGTCACCGAAGGCGCCGTCGCGGTTCAGCCACAGGCGGACCCTACTGGCGGACGCATCATCG
CCGCGGGCAAGCAGGCACGGTTCACCCCGGCGAGCGTCGGTGCGCCCACGCCGCTGCCCGAGAGCGATACCGCCTGGACC
GACGGCATGATCGTCGCCACGGACATGCGCCTGGCGGATTTCCTCGCCGAGGTCGACCGTTACCGACCCGGGCGGCTGCG
CTGCGCCCCGGACGTGGCCGATCTGCGCGTGTCCGGCACCTTTCCAGTAGCCGATACCGATCGCATCCTCGATGCCCTTC
GCACCGCCCTCCCCGTGCGCATCCATTTCCTGACGCGCTACTGGACAACGGTCCTTCCCGCCTGA

Upstream 100 bases:

>100_bases
CGGTGACGACGGTCAAGCGCTATCTGGTTCGCGCCGGCACAAAGTGCTATTTCGCGATGTCCCTCGCATGAGCGCGCAAG
ATCTGGGGATACCACCGCAC

Downstream 100 bases:

>100_bases
CGTTTCGTTTTTTTCCGCCAAGGAGTGGTCTGTTCTGGATTCTCGCGTGACATAGGAGATGAGACCTACTTTCACGCCTC
TCCCGCAGTCGAATCCATGC

Product: FecR-like transmembrane sensor, Fe2+-dicitrate sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MALAAVEWLVTLQGGETDGASHAAWRHWLSQHPDHARAWARIEAVNARLRDVASPLTTAVAHAALTTPRSASRRRAVQAL
VVAFTGGAAAWAARDHAPLQDWLADVSTAVGEQRLLSLADGTQIRLNSDTAIDIAFTATERRVVLRRGEIHVQTAPDRHW
PARPFIVATASATLRPMGTRFAVRVSGDAGWIAVTEGAVAVQPQADPTGGRIIAAGKQARFTPASVGAPTPLPESDTAWT
DGMIVATDMRLADFLAEVDRYRPGRLRCAPDVADLRVSGTFPVADTDRILDALRTALPVRIHFLTRYWTTVLPA

Sequences:

>Translated_314_residues
MALAAVEWLVTLQGGETDGASHAAWRHWLSQHPDHARAWARIEAVNARLRDVASPLTTAVAHAALTTPRSASRRRAVQAL
VVAFTGGAAAWAARDHAPLQDWLADVSTAVGEQRLLSLADGTQIRLNSDTAIDIAFTATERRVVLRRGEIHVQTAPDRHW
PARPFIVATASATLRPMGTRFAVRVSGDAGWIAVTEGAVAVQPQADPTGGRIIAAGKQARFTPASVGAPTPLPESDTAWT
DGMIVATDMRLADFLAEVDRYRPGRLRCAPDVADLRVSGTFPVADTDRILDALRTALPVRIHFLTRYWTTVLPA
>Mature_313_residues
ALAAVEWLVTLQGGETDGASHAAWRHWLSQHPDHARAWARIEAVNARLRDVASPLTTAVAHAALTTPRSASRRRAVQALV
VAFTGGAAAWAARDHAPLQDWLADVSTAVGEQRLLSLADGTQIRLNSDTAIDIAFTATERRVVLRRGEIHVQTAPDRHWP
ARPFIVATASATLRPMGTRFAVRVSGDAGWIAVTEGAVAVQPQADPTGGRIIAAGKQARFTPASVGAPTPLPESDTAWTD
GMIVATDMRLADFLAEVDRYRPGRLRCAPDVADLRVSGTFPVADTDRILDALRTALPVRIHFLTRYWTTVLPA

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=310, Percent_Identity=33.8709677419355, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 33825; Mature: 33693

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAAVEWLVTLQGGETDGASHAAWRHWLSQHPDHARAWARIEAVNARLRDVASPLTTAV
CCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AHAALTTPRSASRRRAVQALVVAFTGGAAAWAARDHAPLQDWLADVSTAVGEQRLLSLAD
HHHHHCCCCCHHHHHHHHEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GTQIRLNSDTAIDIAFTATERRVVLRRGEIHVQTAPDRHWPARPFIVATASATLRPMGTR
CCEEEECCCCEEEEEEECCCCEEEEEECEEEEEECCCCCCCCCCEEEEECCCEECCCCCE
FAVRVSGDAGWIAVTEGAVAVQPQADPTGGRIIAAGKQARFTPASVGAPTPLPESDTAWT
EEEEECCCCCEEEEECCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
DGMIVATDMRLADFLAEVDRYRPGRLRCAPDVADLRVSGTFPVADTDRILDALRTALPVR
CCEEEEECHHHHHHHHHHHHCCCCCEEECCCHHHEEECCCCCCCCHHHHHHHHHHHHHHH
IHFLTRYWTTVLPA
HHHHHHHHHHHCCC
>Mature Secondary Structure 
ALAAVEWLVTLQGGETDGASHAAWRHWLSQHPDHARAWARIEAVNARLRDVASPLTTAV
CCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AHAALTTPRSASRRRAVQALVVAFTGGAAAWAARDHAPLQDWLADVSTAVGEQRLLSLAD
HHHHHCCCCCHHHHHHHHEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GTQIRLNSDTAIDIAFTATERRVVLRRGEIHVQTAPDRHWPARPFIVATASATLRPMGTR
CCEEEECCCCEEEEEEECCCCEEEEEECEEEEEECCCCCCCCCCEEEEECCCEECCCCCE
FAVRVSGDAGWIAVTEGAVAVQPQADPTGGRIIAAGKQARFTPASVGAPTPLPESDTAWT
EEEEECCCCCEEEEECCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
DGMIVATDMRLADFLAEVDRYRPGRLRCAPDVADLRVSGTFPVADTDRILDALRTALPVR
CCEEEEECHHHHHHHHHHHHCCCCCEEECCCHHHEEECCCCCCCCHHHHHHHHHHHHHHH
IHFLTRYWTTVLPA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]