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The map label for this gene is coxM [H]

Identifier: 94312883

GI number: 94312883

Start: 514448

End: 515623

Strand: Direct

Name: coxM [H]

Synonym: Rmet_3955

Alternate gene names: 94312883

Gene position: 514448-515623 (Clockwise)

Preceding gene: 94312882

Following gene: 94312884

Centisome position: 19.94

GC content: 63.35

Gene sequence:

>1176_bases
ATGGCGATCGCCATCGCACTCGTCATCATTGTCGTTGCCTCGGTGCTCTTTCATTTCCTGAGCCCGTGGTGGGCGACACC
GCTGGCGTCCAACTGGAAACAGATGGACGACACGCTGACCATTACCCTCGTCATCACCGGCCTGTTCTTTGTCGTTATCA
ACCTGCTCGTCGGATACATCGTCTGGCGCTTCCGTCATCGTGCGGGGCATCGCGCTGCCTATGCGCCGGAGAACCCGAAA
CTGGAGCGCTGGCTGATCGGGTTGACCGCTGTGTGCATCATCGCGTTGCTGGCACCAGGCCTGATCGTCTACGCGGAGTA
CGTGCGGCCACCACGCGATGCGATGGTCATGGAGGTGGTGGGGCAGCAGTGGCAATGGGCCTTCCGCTTCCCCGGCAAAA
GTGGCCAGCTCGGTACCACGGACCCGCGATTCGTCAGCGGCACGAATCCACTCGGCCTGAATCCCGATGATCCAAATGGA
CAGGACAACATACTCGTCATGGGGCCGGAGGTACACCTGCCGCTGAACCGGCCCATCAAGGTGCTCCTGCGCTCGAAGGA
CGTTTTGCACGATTTCTATGTGCCACCGTTCCGCGCGCGCATGAACATGGTGCCCGGCATGGTCACATCGTTCTGGTTCA
CGCCCACCAAGACCGGTCGCTTCGATATTCTTTGTGCACAACTCTGCGGTCTGGGCCACTACAACATGCGCGGCCACGTC
GTGGTCGAGGAGCAGGCCGCTTTCGACACGTGGCTTGCGAAGCAGCAGACGTTCGCGATGACGCTGGCAAAGGTCGCCGC
TCCCACCGCTGCGCCAGCCGAAGGCCCCGCTGTGGCGGGCGCGTCGGCTGGCGCCGCCGATCTCGTGGCGCAGGGCCGCG
CACTGGCGCAAAGCAAAGGATGCGTGGGATGCCATAGCGTCGATGGCAGCGTGGGTGTCGGCCCAAGCTGGAAGGGCCTG
TACGGCAGCACGCAGACCTTCAGCAACGGCAGCAGCGCGACCGTGAACGATGCGTTCCTGAAGACGGAGATCGAGGACCC
GCAGGCCCGCATCGTCAAGGGCTTCGGGCCCGTCATGCCCAAGTTGCCTGTTACCGATGCCGACGTGGTGGCGCTGTCGG
CGTATATCCGTTCGCTGGGTGCTGGCGCAACGGGCACCCCGCAGGCCGGCAAATAG

Upstream 100 bases:

>100_bases
ATGTCGCCTTGCCGTGACCTGAAACGATGCACTAGTCTTAATCCACCTGCGCAGTCTGCGCATTCCTCGCGGCTTTTCGT
CCGCGCGGAGGAGGGGGGTC

Downstream 100 bases:

>100_bases
CGGCCCGGTGCACAGTCAGAGATCGGAGAGCAAAAAGATGGCCTATGCCGATGATGCCGCCCACCACGGCCCACAGAGTT
TCTGGACGCGCTACATCTGG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MAIAIALVIIVVASVLFHFLSPWWATPLASNWKQMDDTLTITLVITGLFFVVINLLVGYIVWRFRHRAGHRAAYAPENPK
LERWLIGLTAVCIIALLAPGLIVYAEYVRPPRDAMVMEVVGQQWQWAFRFPGKSGQLGTTDPRFVSGTNPLGLNPDDPNG
QDNILVMGPEVHLPLNRPIKVLLRSKDVLHDFYVPPFRARMNMVPGMVTSFWFTPTKTGRFDILCAQLCGLGHYNMRGHV
VVEEQAAFDTWLAKQQTFAMTLAKVAAPTAAPAEGPAVAGASAGAADLVAQGRALAQSKGCVGCHSVDGSVGVGPSWKGL
YGSTQTFSNGSSATVNDAFLKTEIEDPQARIVKGFGPVMPKLPVTDADVVALSAYIRSLGAGATGTPQAGK

Sequences:

>Translated_391_residues
MAIAIALVIIVVASVLFHFLSPWWATPLASNWKQMDDTLTITLVITGLFFVVINLLVGYIVWRFRHRAGHRAAYAPENPK
LERWLIGLTAVCIIALLAPGLIVYAEYVRPPRDAMVMEVVGQQWQWAFRFPGKSGQLGTTDPRFVSGTNPLGLNPDDPNG
QDNILVMGPEVHLPLNRPIKVLLRSKDVLHDFYVPPFRARMNMVPGMVTSFWFTPTKTGRFDILCAQLCGLGHYNMRGHV
VVEEQAAFDTWLAKQQTFAMTLAKVAAPTAAPAEGPAVAGASAGAADLVAQGRALAQSKGCVGCHSVDGSVGVGPSWKGL
YGSTQTFSNGSSATVNDAFLKTEIEDPQARIVKGFGPVMPKLPVTDADVVALSAYIRSLGAGATGTPQAGK
>Mature_390_residues
AIAIALVIIVVASVLFHFLSPWWATPLASNWKQMDDTLTITLVITGLFFVVINLLVGYIVWRFRHRAGHRAAYAPENPKL
ERWLIGLTAVCIIALLAPGLIVYAEYVRPPRDAMVMEVVGQQWQWAFRFPGKSGQLGTTDPRFVSGTNPLGLNPDDPNGQ
DNILVMGPEVHLPLNRPIKVLLRSKDVLHDFYVPPFRARMNMVPGMVTSFWFTPTKTGRFDILCAQLCGLGHYNMRGHVV
VEEQAAFDTWLAKQQTFAMTLAKVAAPTAAPAEGPAVAGASAGAADLVAQGRALAQSKGCVGCHSVDGSVGVGPSWKGLY
GSTQTFSNGSSATVNDAFLKTEIEDPQARIVKGFGPVMPKLPVTDADVVALSAYIRSLGAGATGTPQAGK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226540, Length=169, Percent_Identity=26.6272189349112, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 42049; Mature: 41918

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAIALVIIVVASVLFHFLSPWWATPLASNWKQMDDTLTITLVITGLFFVVINLLVGYI
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHH
VWRFRHRAGHRAAYAPENPKLERWLIGLTAVCIIALLAPGLIVYAEYVRPPRDAMVMEVV
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHH
GQQWQWAFRFPGKSGQLGTTDPRFVSGTNPLGLNPDDPNGQDNILVMGPEVHLPLNRPIK
CCCCEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHH
VLLRSKDVLHDFYVPPFRARMNMVPGMVTSFWFTPTKTGRFDILCAQLCGLGHYNMRGHV
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCEE
VVEEQAAFDTWLAKQQTFAMTLAKVAAPTAAPAEGPAVAGASAGAADLVAQGRALAQSKG
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
CVGCHSVDGSVGVGPSWKGLYGSTQTFSNGSSATVNDAFLKTEIEDPQARIVKGFGPVMP
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHEEECCCCHHHHHHHHHCCCCC
KLPVTDADVVALSAYIRSLGAGATGTPQAGK
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AIAIALVIIVVASVLFHFLSPWWATPLASNWKQMDDTLTITLVITGLFFVVINLLVGYI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHH
VWRFRHRAGHRAAYAPENPKLERWLIGLTAVCIIALLAPGLIVYAEYVRPPRDAMVMEVV
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHH
GQQWQWAFRFPGKSGQLGTTDPRFVSGTNPLGLNPDDPNGQDNILVMGPEVHLPLNRPIK
CCCCEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHH
VLLRSKDVLHDFYVPPFRARMNMVPGMVTSFWFTPTKTGRFDILCAQLCGLGHYNMRGHV
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCEE
VVEEQAAFDTWLAKQQTFAMTLAKVAAPTAAPAEGPAVAGASAGAADLVAQGRALAQSKG
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
CVGCHSVDGSVGVGPSWKGLYGSTQTFSNGSSATVNDAFLKTEIEDPQARIVKGFGPVMP
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHEEECCCCHHHHHHHHHCCCCC
KLPVTDADVVALSAYIRSLGAGATGTPQAGK
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]