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The map label for this gene is acrB [H]

Identifier: 94312852

GI number: 94312852

Start: 480365

End: 483511

Strand: Direct

Name: acrB [H]

Synonym: Rmet_3924

Alternate gene names: 94312852

Gene position: 480365-483511 (Clockwise)

Preceding gene: 94312851

Following gene: 94312853

Centisome position: 18.62

GC content: 62.22

Gene sequence:

>3147_bases
ATGTCTAATTTCTTTATCGAGCGGCCGATCTTTGCCTGGGTGATCGCGCTGGTCATCATGCTGGCCGGCGTGCTCTCCAT
CAGAACGCTGCCGATCAACCAGTACCCGGCGATCGCCCCGCCGACCATCGCCATCTCCGTAACCTACCCGGGCGCTTCGG
CGCAAACGGTGCAGGATACGGTGGTGCAGGTGATCGAGCAGCAGCTGAATGGCCTGGATCGCCTCCGCTACATCTCGTCG
GAATCGAACTCCGACGGCAGCATGACCATCACGGTCACGTTCGAGCAAGGCACCAACCCGGATATCGCGCAGGTGCAGGT
GCAGAACAAGCTTGCCCTAGCCACGCCACTGTTGCCGCAGGAAGTTCAGCAGCAGGGGATTCGCGTAACCAAGTCGGTGC
GTAACTTCCTGCTGATCGTGGGTCTGATTTCGACCGACCCCAACATGACGCGGGAGGATTTGTCGAACTACATCGTTTCG
AACATCCAGGATCCGCTATCGCGTACCGCAGGCGTGGGCGACTTCCAGGTGTTCGGCTCGCAGTATGCGATGCGGATCTG
GCTGGACCCGGCCAAGCTCAACAGCTACCAGCTCGCGCCGCTGGATGTGAGCAACGCGATCAAGGCCCAGAACGTCCAGG
TGGCTTCGGGTCAGCTTGGTGGCCTGCCGGCGGTTCGCGGACAGCAGCTTAATGCGACGGTGATTGGCAAGACGCGTCTC
CAGACCGCCGAGCAGTTTGGCGACATCCTGCTCAAGGTCAATCCCGACGGCTCGCAGGTGCGCCTGAAGGACGTGGCCGA
TGTTGCTCTGGGTGGCCAGGACTACACGATCAACGCGCAGTACAACGGTCGCCCGGCATCGGGTATCGCGATTCGCCTGG
CATCCGGCGCCAACGCGCTGGAGACGGTCAAGAACATCCACAATACGCTGGCTCAGCTGGAACCGACGTTCCCGCCGGGC
ATCAAGGTGGTGTTCCCGTATGACACGACGCCGGTGATCTCCGACTCGATCCACGAGGTGATCAAGACGCTGCTCGAGGC
AATCGTGCTCGTCTTCCTGGTGATGTATCTGTTCCTGCAGAACTTCCGCGCCACGCTGATCCCAACGATCGCGGTGCCGG
TGGTGCTGCTCGGCACGTTCGGCGTGTTGGCCGCGTTTGGCTATTCGATCAACACACTGACGATGTTCGGCATGGTGCTG
GCCATCGGTCTGCTGGTGGACGATGCCATCGTGGTGGTCGAGAACGTCGAGCGGGTGATGGCCGAAGACGGGCTGGGGCC
AAAGGAAGCCGCACGAAAATCGATGGGGCAGATCCAGGGCGCGCTGGTTGGTATCGCGCTGGTGCTGTCCGCGGTGTTCC
TGCCGATGGCGTTCTTCGGGGGCTCGACGGGTGTGATCTATCGCCAGTTCTCGATCACGATCGTTTCCGCGATGGTGCTG
TCTGTGCTCGTGGCGCTTGTTCTCACGCCGGCACTGTGCGCGACGATGCTCCAGCCGATCGAGAAGGGCGATCACGGCGA
GCACAAGCAGGGCTTCTTCGGCTGGTTCAACCGCAGCTTCATCCGGTCGACGCAAAGCTATGAGCGTGGGGTCTCCGGCA
TTCTCAAGCGCCGGGCTCCGTTCCTGCTGATCTATCTGGCGATCGTGGTGGTGATGGGATTCCTGTTCACGCGCATCCCG
ACCTCGTTCCTGCCGGAAGAAGATCAGGGCGTGCTGTACGCGCAGGTGCAGACACCGGCCGGCTCGTCGGCCGAGCGCAC
GCAGGCCGTGCTTGACCAGATGCGCAACTACCTGCTGAATGACGAAGGCAAGATCGTGGAGTCGCTCTTTACCGTGAACG
GCTTCAACTTTGCCGGCCGTGGCCAGAGTTCGGGTCTCGCGTTTATTCTGCTGAAGCCGTTCAAGGATCGCGAAGGCGAT
GCCACGAGTGTGTTCGACCTGACCAAGCGGGCGCAGGCCAAGTTCAGCACGTTCCGCGACTCGCTGGCATTTGCCTTCGC
GCCGCCGGCGGTGCAGGAACTCGGTAACGCCACGGGCTTCGACTTCTATATGCAGGATCAGGCCGGCCTGGGGCACGACG
CGCTGATGAACGCGCGCAACAAGTTCCTGTCGCTCGCAGCCAAGAACCCCGCGTTGCAGCGAGTGCGTCCGAACGGCCTC
AATGACGAGCCGCAGTACGTCCTCGAAATCGACGATGAGCGCGCGCGCGCGTTGGGGCTGTCTCTGGCGGACATCAACAG
CACGGTGTCAATTGCCTGGGGTTCCAGCTACGTGAACGACTTCATTGACCGGGGCCGCGTCAAGCGTGTGTACCTGCAGG
GTCGGCCGAACTCGCGAATGTCGCCAGAGGACCTCAACAAGTGGTTCGTGCGCAACGACAAGGGTGACATGGTGCCGTTC
TCGTCGTTTGCCACGGGCAAGTGGGGCTTTGGATCGCCGAAGCTGCAGCGCTACAACGGTGTGCCGGCGGTGGAAATCCT
CGGTGAGCCGGCGGCAGGCAAGAGCTCGGGTGAAGCCATGGCGGCGGTAGAGGAAATCATGAAGCAGATGCCAGCCGGCA
TCTCCTATTCGTGGACGGGCCTGTCGTACGAAGAACGGTTGTCGGGCTCCCAGGCACCAGCGCTGTACGCGTTGTCGCTG
CTGGTGGTCTTCCTCTGTCTGGCGGCGCTGTATGAAAGCTGGTCGATTCCGTTCTCGGTGATGCTGGTGGTGCCGCTCGG
GGTGATCGGCGCGCTGCTGGCTACACTCGCACGAGGACTGTCGAACGACGTGTTCTTCCAGGTGGGGCTGTTGACCACGG
TGGGCCTTTCCGCGAAGAACGCGATTCTGATCGTGGAATTCGCCAAGGAACTGCACGATCACGGCAAGGGCCTCGTGGAG
GCGGCGGTGGAGGCGTGCCGAATGCGTTTACGCCCCATCATCATGACCTCGATGGCGTTCATGCTGGGCGTGTTCCCGCT
GGCGGTGTCGCAAGGCGCCGGCGCGGGTAGCCAGCACGCCATCGGTACCGGCGTGATCGGCGGCATGATCACCGCCACCG
TGCTCGCCATCTTCTGGGTGCCGCTGTTCTTTGTCGTGGTCAGCGCGCTCAAGGAGCGGCGCGGCAAGTCCGATTCGTCC
TCCCTCGAGAAGGGAGCCCAAGCATGA

Upstream 100 bases:

>100_bases
CCGATGCGGCCACAGCCGGCCCCGTGGAGGCCTCGGCACCGAGCGCGGCGTCGGCCCCCGCGGCAAAGTCCTGAACGGGA
CGGACGCATGAGGATTCGCC

Downstream 100 bases:

>100_bases
GAAAGACGCTACTTTGCCTGGCCGCCGTGGCGGCGCTTAGCGGCTGCAGCCTGATTCCCAACTACCAGCGGCCCGCCGCG
CCGGTCGATGCGACGTTCCC

Product: multidrug efflux system

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1048; Mature: 1047

Protein sequence:

>1048_residues
MSNFFIERPIFAWVIALVIMLAGVLSIRTLPINQYPAIAPPTIAISVTYPGASAQTVQDTVVQVIEQQLNGLDRLRYISS
ESNSDGSMTITVTFEQGTNPDIAQVQVQNKLALATPLLPQEVQQQGIRVTKSVRNFLLIVGLISTDPNMTREDLSNYIVS
NIQDPLSRTAGVGDFQVFGSQYAMRIWLDPAKLNSYQLAPLDVSNAIKAQNVQVASGQLGGLPAVRGQQLNATVIGKTRL
QTAEQFGDILLKVNPDGSQVRLKDVADVALGGQDYTINAQYNGRPASGIAIRLASGANALETVKNIHNTLAQLEPTFPPG
IKVVFPYDTTPVISDSIHEVIKTLLEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGMVL
AIGLLVDDAIVVVENVERVMAEDGLGPKEAARKSMGQIQGALVGIALVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMVL
SVLVALVLTPALCATMLQPIEKGDHGEHKQGFFGWFNRSFIRSTQSYERGVSGILKRRAPFLLIYLAIVVVMGFLFTRIP
TSFLPEEDQGVLYAQVQTPAGSSAERTQAVLDQMRNYLLNDEGKIVESLFTVNGFNFAGRGQSSGLAFILLKPFKDREGD
ATSVFDLTKRAQAKFSTFRDSLAFAFAPPAVQELGNATGFDFYMQDQAGLGHDALMNARNKFLSLAAKNPALQRVRPNGL
NDEPQYVLEIDDERARALGLSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPNSRMSPEDLNKWFVRNDKGDMVPF
SSFATGKWGFGSPKLQRYNGVPAVEILGEPAAGKSSGEAMAAVEEIMKQMPAGISYSWTGLSYEERLSGSQAPALYALSL
LVVFLCLAALYESWSIPFSVMLVVPLGVIGALLATLARGLSNDVFFQVGLLTTVGLSAKNAILIVEFAKELHDHGKGLVE
AAVEACRMRLRPIIMTSMAFMLGVFPLAVSQGAGAGSQHAIGTGVIGGMITATVLAIFWVPLFFVVVSALKERRGKSDSS
SLEKGAQA

Sequences:

>Translated_1048_residues
MSNFFIERPIFAWVIALVIMLAGVLSIRTLPINQYPAIAPPTIAISVTYPGASAQTVQDTVVQVIEQQLNGLDRLRYISS
ESNSDGSMTITVTFEQGTNPDIAQVQVQNKLALATPLLPQEVQQQGIRVTKSVRNFLLIVGLISTDPNMTREDLSNYIVS
NIQDPLSRTAGVGDFQVFGSQYAMRIWLDPAKLNSYQLAPLDVSNAIKAQNVQVASGQLGGLPAVRGQQLNATVIGKTRL
QTAEQFGDILLKVNPDGSQVRLKDVADVALGGQDYTINAQYNGRPASGIAIRLASGANALETVKNIHNTLAQLEPTFPPG
IKVVFPYDTTPVISDSIHEVIKTLLEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGMVL
AIGLLVDDAIVVVENVERVMAEDGLGPKEAARKSMGQIQGALVGIALVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMVL
SVLVALVLTPALCATMLQPIEKGDHGEHKQGFFGWFNRSFIRSTQSYERGVSGILKRRAPFLLIYLAIVVVMGFLFTRIP
TSFLPEEDQGVLYAQVQTPAGSSAERTQAVLDQMRNYLLNDEGKIVESLFTVNGFNFAGRGQSSGLAFILLKPFKDREGD
ATSVFDLTKRAQAKFSTFRDSLAFAFAPPAVQELGNATGFDFYMQDQAGLGHDALMNARNKFLSLAAKNPALQRVRPNGL
NDEPQYVLEIDDERARALGLSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPNSRMSPEDLNKWFVRNDKGDMVPF
SSFATGKWGFGSPKLQRYNGVPAVEILGEPAAGKSSGEAMAAVEEIMKQMPAGISYSWTGLSYEERLSGSQAPALYALSL
LVVFLCLAALYESWSIPFSVMLVVPLGVIGALLATLARGLSNDVFFQVGLLTTVGLSAKNAILIVEFAKELHDHGKGLVE
AAVEACRMRLRPIIMTSMAFMLGVFPLAVSQGAGAGSQHAIGTGVIGGMITATVLAIFWVPLFFVVVSALKERRGKSDSS
SLEKGAQA
>Mature_1047_residues
SNFFIERPIFAWVIALVIMLAGVLSIRTLPINQYPAIAPPTIAISVTYPGASAQTVQDTVVQVIEQQLNGLDRLRYISSE
SNSDGSMTITVTFEQGTNPDIAQVQVQNKLALATPLLPQEVQQQGIRVTKSVRNFLLIVGLISTDPNMTREDLSNYIVSN
IQDPLSRTAGVGDFQVFGSQYAMRIWLDPAKLNSYQLAPLDVSNAIKAQNVQVASGQLGGLPAVRGQQLNATVIGKTRLQ
TAEQFGDILLKVNPDGSQVRLKDVADVALGGQDYTINAQYNGRPASGIAIRLASGANALETVKNIHNTLAQLEPTFPPGI
KVVFPYDTTPVISDSIHEVIKTLLEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGMVLA
IGLLVDDAIVVVENVERVMAEDGLGPKEAARKSMGQIQGALVGIALVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMVLS
VLVALVLTPALCATMLQPIEKGDHGEHKQGFFGWFNRSFIRSTQSYERGVSGILKRRAPFLLIYLAIVVVMGFLFTRIPT
SFLPEEDQGVLYAQVQTPAGSSAERTQAVLDQMRNYLLNDEGKIVESLFTVNGFNFAGRGQSSGLAFILLKPFKDREGDA
TSVFDLTKRAQAKFSTFRDSLAFAFAPPAVQELGNATGFDFYMQDQAGLGHDALMNARNKFLSLAAKNPALQRVRPNGLN
DEPQYVLEIDDERARALGLSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPNSRMSPEDLNKWFVRNDKGDMVPFS
SFATGKWGFGSPKLQRYNGVPAVEILGEPAAGKSSGEAMAAVEEIMKQMPAGISYSWTGLSYEERLSGSQAPALYALSLL
VVFLCLAALYESWSIPFSVMLVVPLGVIGALLATLARGLSNDVFFQVGLLTTVGLSAKNAILIVEFAKELHDHGKGLVEA
AVEACRMRLRPIIMTSMAFMLGVFPLAVSQGAGAGSQHAIGTGVIGGMITATVLAIFWVPLFFVVVSALKERRGKSDSSS
LEKGAQA

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1786667, Length=1019, Percent_Identity=67.4190382728165, Blast_Score=1442, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1019, Percent_Identity=64.4749754661433, Blast_Score=1362, Evalue=0.0,
Organism=Escherichia coli, GI1788814, Length=1027, Percent_Identity=59.6884128529698, Blast_Score=1279, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1020, Percent_Identity=60.8823529411765, Blast_Score=1259, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1045, Percent_Identity=29.6650717703349, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1788391, Length=1041, Percent_Identity=28.9145052833814, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786788, Length=1074, Percent_Identity=22.5325884543762, Blast_Score=180, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 113215; Mature: 113084

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFFIERPIFAWVIALVIMLAGVLSIRTLPINQYPAIAPPTIAISVTYPGASAQTVQDT
CCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHH
VVQVIEQQLNGLDRLRYISSESNSDGSMTITVTFEQGTNPDIAQVQVQNKLALATPLLPQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCHHHHCCCCHH
EVQQQGIRVTKSVRNFLLIVGLISTDPNMTREDLSNYIVSNIQDPLSRTAGVGDFQVFGS
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
QYAMRIWLDPAKLNSYQLAPLDVSNAIKAQNVQVASGQLGGLPAVRGQQLNATVIGKTRL
CEEEEEEECHHHCCCEEECCCCHHCCHHHCCEEEECCCCCCCCCCCCCCCCEEEECHHHH
QTAEQFGDILLKVNPDGSQVRLKDVADVALGGQDYTINAQYNGRPASGIAIRLASGANAL
HHHHHHCCEEEEECCCCCEEEHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCHH
ETVKNIHNTLAQLEPTFPPGIKVVFPYDTTPVISDSIHEVIKTLLEAIVLVFLVMYLFLQ
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEDGLGPKEAARKSMGQIQGALVGIALVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMVL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
SVLVALVLTPALCATMLQPIEKGDHGEHKQGFFGWFNRSFIRSTQSYERGVSGILKRRAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FLLIYLAIVVVMGFLFTRIPTSFLPEEDQGVLYAQVQTPAGSSAERTQAVLDQMRNYLLN
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
DEGKIVESLFTVNGFNFAGRGQSSGLAFILLKPFKDREGDATSVFDLTKRAQAKFSTFRD
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
SLAFAFAPPAVQELGNATGFDFYMQDQAGLGHDALMNARNKFLSLAAKNPALQRVRPNGL
HHHHHCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
NDEPQYVLEIDDERARALGLSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPNSRM
CCCCCEEEEECCHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHCCCEEEEEEECCCCCCC
SPEDLNKWFVRNDKGDMVPFSSFATGKWGFGSPKLQRYNGVPAVEILGEPAAGKSSGEAM
CHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCHHH
AAVEEIMKQMPAGISYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFSV
HHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MLVVPLGVIGALLATLARGLSNDVFFQVGLLTTVGLSAKNAILIVEFAKELHDHGKGLVE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCEEEHHHHHHHHHHCCHHHH
AAVEACRMRLRPIIMTSMAFMLGVFPLAVSQGAGAGSQHAIGTGVIGGMITATVLAIFWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLFFVVVSALKERRGKSDSSSLEKGAQA
HHHHHHHHHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SNFFIERPIFAWVIALVIMLAGVLSIRTLPINQYPAIAPPTIAISVTYPGASAQTVQDT
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHH
VVQVIEQQLNGLDRLRYISSESNSDGSMTITVTFEQGTNPDIAQVQVQNKLALATPLLPQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCHHHHCCCCHH
EVQQQGIRVTKSVRNFLLIVGLISTDPNMTREDLSNYIVSNIQDPLSRTAGVGDFQVFGS
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
QYAMRIWLDPAKLNSYQLAPLDVSNAIKAQNVQVASGQLGGLPAVRGQQLNATVIGKTRL
CEEEEEEECHHHCCCEEECCCCHHCCHHHCCEEEECCCCCCCCCCCCCCCCEEEECHHHH
QTAEQFGDILLKVNPDGSQVRLKDVADVALGGQDYTINAQYNGRPASGIAIRLASGANAL
HHHHHHCCEEEEECCCCCEEEHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCHH
ETVKNIHNTLAQLEPTFPPGIKVVFPYDTTPVISDSIHEVIKTLLEAIVLVFLVMYLFLQ
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEDGLGPKEAARKSMGQIQGALVGIALVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMVL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
SVLVALVLTPALCATMLQPIEKGDHGEHKQGFFGWFNRSFIRSTQSYERGVSGILKRRAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FLLIYLAIVVVMGFLFTRIPTSFLPEEDQGVLYAQVQTPAGSSAERTQAVLDQMRNYLLN
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
DEGKIVESLFTVNGFNFAGRGQSSGLAFILLKPFKDREGDATSVFDLTKRAQAKFSTFRD
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
SLAFAFAPPAVQELGNATGFDFYMQDQAGLGHDALMNARNKFLSLAAKNPALQRVRPNGL
HHHHHCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
NDEPQYVLEIDDERARALGLSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPNSRM
CCCCCEEEEECCHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHCCCEEEEEEECCCCCCC
SPEDLNKWFVRNDKGDMVPFSSFATGKWGFGSPKLQRYNGVPAVEILGEPAAGKSSGEAM
CHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCHHH
AAVEEIMKQMPAGISYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFSV
HHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MLVVPLGVIGALLATLARGLSNDVFFQVGLLTTVGLSAKNAILIVEFAKELHDHGKGLVE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCEEEHHHHHHHHHHCCHHHH
AAVEACRMRLRPIIMTSMAFMLGVFPLAVSQGAGAGSQHAIGTGVIGGMITATVLAIFWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLFFVVVSALKERRGKSDSSSLEKGAQA
HHHHHHHHHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]