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The map label for this gene is pcaR [H]

Identifier: 94312843

GI number: 94312843

Start: 462744

End: 463556

Strand: Direct

Name: pcaR [H]

Synonym: Rmet_3915

Alternate gene names: 94312843

Gene position: 462744-463556 (Clockwise)

Preceding gene: 94312839

Following gene: 94312844

Centisome position: 17.94

GC content: 64.21

Gene sequence:

>813_bases
ATGCAAATGAACACGCCAGTCGAACAATTCATTGCCGAGCGCCGCCGCGAAGATCCTTCGTTCGGTGGGCTGTTGGCCAA
GGGTTTCGCGCTGCTTCGCTGCTTCATCGACGACCCTCGCCCATTGGGCAACGGAGAACTGGCGCAGCGGCTGCAGTTGC
CGCGGGCCACGGTATCGCGCATCTGCCGCACGTTGTTCGAACTCGGCTACCTCGACTGGGAACCGAAGCTGGACAAGTAC
TTCGTCAGCGCCCAGGTGCTGGCGCTGGGCTATCCGTACATGGCTGGACTGCAGGTCCGCCACCTGGCACGACCGCTGAT
GCAGGCGCTGGCCAATCAGATCGAAGGCGCGGTGTCGATGGGCGTGGCCTACCGGCTCGACGTGACTTACCTGGAATCGT
GCACGCACATGGAAGGCACGCCGGCGCGGCCGGCGATTGGCGCGGTGCGGTCGGTGCTGACGAGCGCGATGGGGCGCGCG
TACCTGTGCACGCTGTCGAAGACCGAATTCGAGAAACTGATGACCACGGCGCGTGCAGAGCGACCCGATGAGTACGCCGC
CTGCTACGAGACCTTGTGCCACTGCATCGCCCACTATCCGAAGCGCGGATTCACGCTCAACGAGGGGGATGCGGGAGCGG
ATGTACATGGCGTGGGGGTGTATTCGCGCGTGGTGTACATGAACCGGCCGCTGCTGTTCAACTGCGCCATCCCCGGGATG
CGCGTCAAGCGGGGCTCGATGGAGAAGCGCGTGGCGCCGCTGCTGCGCGAGATGGTGCGATCGATAGAAAACATGGCTGG
CGTGGGACGCTAG

Upstream 100 bases:

>100_bases
CACCGTCAAGATAGGGGTTACGATTTCCAATATTTGGAAATTCATTCCGCCTTTTGACATACGACGACGTCGCCGACCAC
ACTGGACAACAGGAGACAAG

Downstream 100 bases:

>100_bases
GCCGCCGGTAGGCGGGACCGGACCTTCCCGCCAGGCTGAACGCGTCGCGGCACGTATCGCGCGCGTCATCAACGGAGACA
ACATGCAGGATCTGCAACCC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQMNTPVEQFIAERRREDPSFGGLLAKGFALLRCFIDDPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWEPKLDKY
FVSAQVLALGYPYMAGLQVRHLARPLMQALANQIEGAVSMGVAYRLDVTYLESCTHMEGTPARPAIGAVRSVLTSAMGRA
YLCTLSKTEFEKLMTTARAERPDEYAACYETLCHCIAHYPKRGFTLNEGDAGADVHGVGVYSRVVYMNRPLLFNCAIPGM
RVKRGSMEKRVAPLLREMVRSIENMAGVGR

Sequences:

>Translated_270_residues
MQMNTPVEQFIAERRREDPSFGGLLAKGFALLRCFIDDPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWEPKLDKY
FVSAQVLALGYPYMAGLQVRHLARPLMQALANQIEGAVSMGVAYRLDVTYLESCTHMEGTPARPAIGAVRSVLTSAMGRA
YLCTLSKTEFEKLMTTARAERPDEYAACYETLCHCIAHYPKRGFTLNEGDAGADVHGVGVYSRVVYMNRPLLFNCAIPGM
RVKRGSMEKRVAPLLREMVRSIENMAGVGR
>Mature_270_residues
MQMNTPVEQFIAERRREDPSFGGLLAKGFALLRCFIDDPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWEPKLDKY
FVSAQVLALGYPYMAGLQVRHLARPLMQALANQIEGAVSMGVAYRLDVTYLESCTHMEGTPARPAIGAVRSVLTSAMGRA
YLCTLSKTEFEKLMTTARAERPDEYAACYETLCHCIAHYPKRGFTLNEGDAGADVHGVGVYSRVVYMNRPLLFNCAIPGM
RVKRGSMEKRVAPLLREMVRSIENMAGVGR

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30132; Mature: 30132

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMNTPVEQFIAERRREDPSFGGLLAKGFALLRCFIDDPRPLGNGELAQRLQLPRATVSR
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHH
ICRTLFELGYLDWEPKLDKYFVSAQVLALGYPYMAGLQVRHLARPLMQALANQIEGAVSM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAYRLDVTYLESCTHMEGTPARPAIGAVRSVLTSAMGRAYLCTLSKTEFEKLMTTARAE
CHHHEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCC
RPDEYAACYETLCHCIAHYPKRGFTLNEGDAGADVHGVGVYSRVVYMNRPLLFNCAIPGM
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEEEECCCCC
RVKRGSMEKRVAPLLREMVRSIENMAGVGR
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQMNTPVEQFIAERRREDPSFGGLLAKGFALLRCFIDDPRPLGNGELAQRLQLPRATVSR
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHH
ICRTLFELGYLDWEPKLDKYFVSAQVLALGYPYMAGLQVRHLARPLMQALANQIEGAVSM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAYRLDVTYLESCTHMEGTPARPAIGAVRSVLTSAMGRAYLCTLSKTEFEKLMTTARAE
CHHHEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCC
RPDEYAACYETLCHCIAHYPKRGFTLNEGDAGADVHGVGVYSRVVYMNRPLLFNCAIPGM
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEEEECCCCC
RVKRGSMEKRVAPLLREMVRSIENMAGVGR
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]