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The map label for this gene is rnpA [H]

Identifier: 94312546

GI number: 94312546

Start: 3926622

End: 3927779

Strand: Reverse

Name: rnpA [H]

Synonym: Rmet_3615

Alternate gene names: 94312546

Gene position: 3927779-3926622 (Counterclockwise)

Preceding gene: NA

Following gene: 94312545

Centisome position: 99.99

GC content: 65.72

Gene sequence:

>1158_bases
ATGACCGGGAATACCCACAGAGTTACCCACTGCGACTTGTGGACAATGGCGCACCACGTCGGCGTGACGGATTCGCCGCC
GCCACCGGCCTCAACCATCGGACGCCTTGACAGGCTCAACGAATATCGGTTAAATGGCGGGTTCTGCGATGCGGCAGGGG
ATCACGTATGCGCATCGCCGGGTCTGGCCCGTACCGTGCGTGTGAACCATGTGCGGCATCAGGCAAGCGGCCTGATCCCC
GCCGGCGCTTCGTCCAATGTGGCGATGCCAGCGGCGGCCGGCAGCAAGACAGAACCAGAATCGTCGGCAAGGCCGCAGCT
TTCCCAGAGTCTGCATCGCGGCACAGCCCCATGCGAACCATACGCGGCGGCCAAGGCGCCCCGGCAAATCGCCGGCGCCC
GGAAAGCCCGGATCAACCAGAGAGTGCAACATGAAACGTACCTATCAACCTTCCGTTACCCGCCGCAAGCGTACCCATGG
TTTCCGCGTGCGCATGAAGACCCGTGGCGGCCGTGCCGTGATCAACGCACGCCGCGCCAAGGGCCGCAAGCGCCTGGCGA
TCTGAGTGCCGGGCGACCGGCCCGGGCGGTGAACGTCGGGTTGCGCGATTCGCGCTGCCTCGATGAAAGCCTGCCCGGCC
AAGCGCCTCGCACTCAGGATGGCCGGGAGCACTGCCCGTCGAAGCCCAGCTTGCCGCTAGCTTTGCCAAGCGTGTCGAAC
CATGCCTTTCCCAAAGCCGCGAGGCTCACAAAGACGGATGAGTTTTCATCCGTTTTTGCTTTGCGGCCCCGGCGTCGCAC
TACGCACTTCGTGCTGTACGTGCGCGCCAACGGCCAGGCGCAGGCCCGGCTGGGCATCGTCGTCGGCAAGAAATTCGCAC
CACGCGCGGCCGAGCGTAATCTCGTGAAGCGCATGGTGCGGGAACTGTTTCGGAGCCGGCAGGCCCAATTCGCGGGCCGC
GATATTCTGCTGCGCCTGCAAGCGAAGTTTCCGCGCGCGGAGTTCTCCAGCCGGGTTGCAATCCGCAAGGCCTGCCATGC
GGAGATCAGCGGATTGCTGGACGTGGCGGCCAAGCCGCTACCCGTTGCGCCCGCCGTACCCACGGCACCGCCGACGGCTT
CTGCGGATGTGCCCACCACGCCCGAGGCGCCTGCCTGA

Upstream 100 bases:

>100_bases
GCTGTGCACAACCATGTCAGAAGCCGTTCTCGGTACAAGGCAAAAACGACCAATTGGCTATCGAAAACAATGACTTGATT
GCTGTCGGTAATGCGTATGG

Downstream 100 bases:

>100_bases
CCACCACCATGAAGCGAATCCTGCTTGCCCTGCTGCGCATCTACAAGATCGCCCTGAGTCCTTACCTGGGCTCGCAGTGC
CGCTTCCTGCCCACATGTTC

Product: Ribonuclease P protein component (modular protein)

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTGNTHRVTHCDLWTMAHHVGVTDSPPPPASTIGRLDRLNEYRLNGGFCDAAGDHVCASPGLARTVRVNHVRHQASGLIP
AGASSNVAMPAAAGSKTEPESSARPQLSQSLHRGTAPCEPYAAAKAPRQIAGARKARINQRVQHETYLSTFRYPPQAYPW
FPRAHEDPWRPCRDQRTPRQGPQAPGDLSAGRPARAVNVGLRDSRCLDESLPGQAPRTQDGREHCPSKPSLPLALPSVSN
HAFPKAARLTKTDEFSSVFALRPRRRTTHFVLYVRANGQAQARLGIVVGKKFAPRAAERNLVKRMVRELFRSRQAQFAGR
DILLRLQAKFPRAEFSSRVAIRKACHAEISGLLDVAAKPLPVAPAVPTAPPTASADVPTTPEAPA

Sequences:

>Translated_385_residues
MTGNTHRVTHCDLWTMAHHVGVTDSPPPPASTIGRLDRLNEYRLNGGFCDAAGDHVCASPGLARTVRVNHVRHQASGLIP
AGASSNVAMPAAAGSKTEPESSARPQLSQSLHRGTAPCEPYAAAKAPRQIAGARKARINQRVQHETYLSTFRYPPQAYPW
FPRAHEDPWRPCRDQRTPRQGPQAPGDLSAGRPARAVNVGLRDSRCLDESLPGQAPRTQDGREHCPSKPSLPLALPSVSN
HAFPKAARLTKTDEFSSVFALRPRRRTTHFVLYVRANGQAQARLGIVVGKKFAPRAAERNLVKRMVRELFRSRQAQFAGR
DILLRLQAKFPRAEFSSRVAIRKACHAEISGLLDVAAKPLPVAPAVPTAPPTASADVPTTPEAPA
>Mature_384_residues
TGNTHRVTHCDLWTMAHHVGVTDSPPPPASTIGRLDRLNEYRLNGGFCDAAGDHVCASPGLARTVRVNHVRHQASGLIPA
GASSNVAMPAAAGSKTEPESSARPQLSQSLHRGTAPCEPYAAAKAPRQIAGARKARINQRVQHETYLSTFRYPPQAYPWF
PRAHEDPWRPCRDQRTPRQGPQAPGDLSAGRPARAVNVGLRDSRCLDESLPGQAPRTQDGREHCPSKPSLPLALPSVSNH
AFPKAARLTKTDEFSSVFALRPRRRTTHFVLYVRANGQAQARLGIVVGKKFAPRAAERNLVKRMVRELFRSRQAQFAGRD
ILLRLQAKFPRAEFSSRVAIRKACHAEISGLLDVAAKPLPVAPAVPTAPPTASADVPTTPEAPA

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- ProDom:   PD003629 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 41814; Mature: 41683

Theoretical pI: Translated: 11.27; Mature: 11.27

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNTHRVTHCDLWTMAHHVGVTDSPPPPASTIGRLDRLNEYRLNGGFCDAAGDHVCASP
CCCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
GLARTVRVNHVRHQASGLIPAGASSNVAMPAAAGSKTEPESSARPQLSQSLHRGTAPCEP
CCHHEEHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
YAAAKAPRQIAGARKARINQRVQHETYLSTFRYPPQAYPWFPRAHEDPWRPCRDQRTPRQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPQAPGDLSAGRPARAVNVGLRDSRCLDESLPGQAPRTQDGREHCPSKPSLPLALPSVSN
CCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCCEECCCCCC
HAFPKAARLTKTDEFSSVFALRPRRRTTHFVLYVRANGQAQARLGIVVGKKFAPRAAERN
CCCCCHHHCCCCHHHHHHHEECCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHH
LVKRMVRELFRSRQAQFAGRDILLRLQAKFPRAEFSSRVAIRKACHAEISGLLDVAAKPL
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVAPAVPTAPPTASADVPTTPEAPA
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGNTHRVTHCDLWTMAHHVGVTDSPPPPASTIGRLDRLNEYRLNGGFCDAAGDHVCASP
CCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
GLARTVRVNHVRHQASGLIPAGASSNVAMPAAAGSKTEPESSARPQLSQSLHRGTAPCEP
CCHHEEHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
YAAAKAPRQIAGARKARINQRVQHETYLSTFRYPPQAYPWFPRAHEDPWRPCRDQRTPRQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPQAPGDLSAGRPARAVNVGLRDSRCLDESLPGQAPRTQDGREHCPSKPSLPLALPSVSN
CCCCCCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCCEECCCCCC
HAFPKAARLTKTDEFSSVFALRPRRRTTHFVLYVRANGQAQARLGIVVGKKFAPRAAERN
CCCCCHHHCCCCHHHHHHHEECCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHH
LVKRMVRELFRSRQAQFAGRDILLRLQAKFPRAEFSSRVAIRKACHAEISGLLDVAAKPL
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVAPAVPTAPPTASADVPTTPEAPA
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA