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The map label for this gene is ntrY [H]

Identifier: 94312491

GI number: 94312491

Start: 3860067

End: 3862550

Strand: Reverse

Name: ntrY [H]

Synonym: Rmet_3560

Alternate gene names: 94312491

Gene position: 3862550-3860067 (Counterclockwise)

Preceding gene: 94312492

Following gene: 94312490

Centisome position: 98.33

GC content: 63.77

Gene sequence:

>2484_bases
ATGAACGGCAATCCGTGGGACAGCAGATTCCGACGCCTGCTCTATCGCGTCGTGGTGGGCATCATCGTCTTCCTGGCGTT
GGTGCTGGTGGGACTGCTAGCCGGAGCCTCGGCCAATACCGAGTTCTTCGACCGCTATTTCACGCTGCTCTTCAAGATCA
ATCTCGTCGTCGGCGCCTTGCTGGTGCTGACCGTGGGCGCGCTCGCGCTGACGCTCTGGCTGCGCTATCGCCGCGGCAAG
TTCGGCACGCGGCTGATGTCGAAGCTTGCCGTGTTCTTCGGCGTGGTGGGCGTATTGCCGGGCGTTCTGATCTATCTCGT
CTCGCTGCAGTTTGTTTCCCGCAGTATCGAGTCGTGGTTCGACGTGCGCGTGGAAACCGCGCTCGAGGCCGGCCTCAATC
TCGGCCGCTCCACCATCGACAGCCAGTTGGCCGACCTTCAGGGCAAGGCACGCTTGATGGCCGACCAGCTGACCGGCTCG
ACCGGCATGGCAACGTCACTGCAACTGAACCGCCTGCGCGAGCAGTACGGCGTACAGGAAGCCGCGATCTTTACAGGCAG
CGGCCGCGTGCTGGCAACCGCGTCGAGCAGCTATGCGTCGCTGGTGCCGGACCTGCCATCCGGCGTGCTGGCAGAGCAAG
CGCGCATGGCCGGAGGCTATGCGGCAGTGGAGGGTGGCACCGATCCGTCGACTGGCGACAAACCGCAGCCCAATGTCGAT
AGCAGCCATCTCTACCGGCTGCGCGTGATCATTCCGCTGGGGCCCGCGCCGAGCGCGGCAGCCTCCGACGATCAGGCACA
GGCCACTGCAAGCGCTGCCGTAGCCGCGGCGGCGCGTACCCAGCATCCCCCGCCAAAACTCGGCCTGCCCGTGCCGAGCA
GTCGTTGGGCAGGCTCGGGCCTGTCCGTGGAGCGCCGCCCCGAGGATGCGCCCGCCACGGGCTTCGGCCTGGTGGGCGAC
ACTGTGCGCGAGGAGCGATACCTGCAGGTCCTGCACCCGGTACCTGGCGTGCTGGCGCGCAATGCCGACGAGGTCCAGCG
GGCCTATCAGGAATATCAGGAAAAGGCGCTGGGCCGCACCGGCCTGCGCAAGATGTACATTGGCACGCTGACGCTGACGC
TGTTCCTCGCCGTGTTTATCGCCGTGATGCTGGCGCTGCTGCTGGGCGGCCAGCTAGCCCGCCCGCTGCTGATGCTGCTG
CAGGGCACGAAGGAAGTGGCGGAGGGCGACCTCTCTCCCAAGCGTGAACTCAAGAGCCGCGACGAACTCGGGATGCTGAC
CCAGCAGTTCAACCAGATGACGCGCCAGCTTGCTGAAGCGCGCATCGCCGTGGAAGAGAATCGCAGTGCGCTCGAGCAGT
CGAAGGCGTATCTGGAAAGCGTGCTGCGGAATCTGACCGCAGGTGTGCTCGTGTTCGACCGGCGCTTTGTGCTGATCACC
ACCAACCCCGGCGCCGAGCGCATCTTCCGCCAGCCGCTCAACGGTGTGCTGGGGCACCCGGTGGAACAGATCCCCGGCAT
GAACGACTTCGCGGAGATCGTGCGTCAGGCATTTTCCGAGCAGACCACCAGCGAGGTCCTGGGTGGCGCGCAGCACTGGC
AGAAGCAGATCGAGTTGCCGCAGGGCGACGAGGAGCAGCCGCTCACACTGCTGGTTCGCGGCGCGCATCTTCCTGGCGGC
AGCCATGACGAACCGGGCTACGTGGTGGTGTTCGACGATATCTCAGACGTGATCTCGGCACAGCGTTCGGTGGCCTGGGG
AGAAGTGGCGCGCCGTCTTGCCCACGAGATCAAGAATCCGCTGACACCGATCCAGCTATCGGCGGAACGGCTGCAGATGA
AGCTGTCCCCTAAACTTGAGACGTCGGATGCCGAAGTACTGAAACGTGGGGCGGCGACAATCGTCAACCAGGTGGCAGCG
ATGAAGCGCATGGTCGATGATTTCCGCGACTACGCGCGCACGCCGCCGGCTGTGATGCAGTCGCTGCCGCTCAACGGCCT
GGTGTCGGAAGTCCTGCATCTTTACGGCATCGATGACCCTGCCGTGCACGAGCACCCCGTGATCCATCCGACGCTGGACA
CGGATATGCCTGAAATCAAAGGCGATCCGACCCAACTCAGGCAAGTGATTCACAACCTGTTGCAAAATGCCCAGGATGCG
GTGGCGGAGAACGTTGCGGCCGGTAGGGCGGCGCCCCATATCACTCTGCACACCGAGACTGTAGAATACAAAGATTCTGC
CGGCGAAGACCGGCAAGCCGTCAAGCTGTCCATAGCGGACAATGGCCCCGGCTTCGCACCACGGATTCTGAGCCGCGCGT
TCGAACCCTATGTGACCACGAAGGCCAAGGGCACGGGTCTCGGGCTGGCGATGGTGAAAAAGATCATTGACGAACATGGC
GCACGCATCGAGGTGCGCAATCGCATGAACGGCACCGAGATCATTGGCGCTCAGATCTCGATCCTGTTCGTTAAGCTGGC
ATAG

Upstream 100 bases:

>100_bases
CGCCCGCTTCGGCCGTCAGCGGAGAACCACGCACGCAGTTCTCGCAAACGCTGTCTAACGCGTTGTCCACGAACCAACTG
GTCCAGCCGGTCAGCCAGCC

Downstream 100 bases:

>100_bases
TCAATCTTGCGCACCGGCAACGTCCGGTGACGCTGCGGTGGGGTTAAGAGGAACGTATGGCAACCATCCTCGTAGTCGAT
GACGAAATGGGTATCCGGGA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 827; Mature: 827

Protein sequence:

>827_residues
MNGNPWDSRFRRLLYRVVVGIIVFLALVLVGLLAGASANTEFFDRYFTLLFKINLVVGALLVLTVGALALTLWLRYRRGK
FGTRLMSKLAVFFGVVGVLPGVLIYLVSLQFVSRSIESWFDVRVETALEAGLNLGRSTIDSQLADLQGKARLMADQLTGS
TGMATSLQLNRLREQYGVQEAAIFTGSGRVLATASSSYASLVPDLPSGVLAEQARMAGGYAAVEGGTDPSTGDKPQPNVD
SSHLYRLRVIIPLGPAPSAAASDDQAQATASAAVAAAARTQHPPPKLGLPVPSSRWAGSGLSVERRPEDAPATGFGLVGD
TVREERYLQVLHPVPGVLARNADEVQRAYQEYQEKALGRTGLRKMYIGTLTLTLFLAVFIAVMLALLLGGQLARPLLMLL
QGTKEVAEGDLSPKRELKSRDELGMLTQQFNQMTRQLAEARIAVEENRSALEQSKAYLESVLRNLTAGVLVFDRRFVLIT
TNPGAERIFRQPLNGVLGHPVEQIPGMNDFAEIVRQAFSEQTTSEVLGGAQHWQKQIELPQGDEEQPLTLLVRGAHLPGG
SHDEPGYVVVFDDISDVISAQRSVAWGEVARRLAHEIKNPLTPIQLSAERLQMKLSPKLETSDAEVLKRGAATIVNQVAA
MKRMVDDFRDYARTPPAVMQSLPLNGLVSEVLHLYGIDDPAVHEHPVIHPTLDTDMPEIKGDPTQLRQVIHNLLQNAQDA
VAENVAAGRAAPHITLHTETVEYKDSAGEDRQAVKLSIADNGPGFAPRILSRAFEPYVTTKAKGTGLGLAMVKKIIDEHG
ARIEVRNRMNGTEIIGAQISILFVKLA

Sequences:

>Translated_827_residues
MNGNPWDSRFRRLLYRVVVGIIVFLALVLVGLLAGASANTEFFDRYFTLLFKINLVVGALLVLTVGALALTLWLRYRRGK
FGTRLMSKLAVFFGVVGVLPGVLIYLVSLQFVSRSIESWFDVRVETALEAGLNLGRSTIDSQLADLQGKARLMADQLTGS
TGMATSLQLNRLREQYGVQEAAIFTGSGRVLATASSSYASLVPDLPSGVLAEQARMAGGYAAVEGGTDPSTGDKPQPNVD
SSHLYRLRVIIPLGPAPSAAASDDQAQATASAAVAAAARTQHPPPKLGLPVPSSRWAGSGLSVERRPEDAPATGFGLVGD
TVREERYLQVLHPVPGVLARNADEVQRAYQEYQEKALGRTGLRKMYIGTLTLTLFLAVFIAVMLALLLGGQLARPLLMLL
QGTKEVAEGDLSPKRELKSRDELGMLTQQFNQMTRQLAEARIAVEENRSALEQSKAYLESVLRNLTAGVLVFDRRFVLIT
TNPGAERIFRQPLNGVLGHPVEQIPGMNDFAEIVRQAFSEQTTSEVLGGAQHWQKQIELPQGDEEQPLTLLVRGAHLPGG
SHDEPGYVVVFDDISDVISAQRSVAWGEVARRLAHEIKNPLTPIQLSAERLQMKLSPKLETSDAEVLKRGAATIVNQVAA
MKRMVDDFRDYARTPPAVMQSLPLNGLVSEVLHLYGIDDPAVHEHPVIHPTLDTDMPEIKGDPTQLRQVIHNLLQNAQDA
VAENVAAGRAAPHITLHTETVEYKDSAGEDRQAVKLSIADNGPGFAPRILSRAFEPYVTTKAKGTGLGLAMVKKIIDEHG
ARIEVRNRMNGTEIIGAQISILFVKLA
>Mature_827_residues
MNGNPWDSRFRRLLYRVVVGIIVFLALVLVGLLAGASANTEFFDRYFTLLFKINLVVGALLVLTVGALALTLWLRYRRGK
FGTRLMSKLAVFFGVVGVLPGVLIYLVSLQFVSRSIESWFDVRVETALEAGLNLGRSTIDSQLADLQGKARLMADQLTGS
TGMATSLQLNRLREQYGVQEAAIFTGSGRVLATASSSYASLVPDLPSGVLAEQARMAGGYAAVEGGTDPSTGDKPQPNVD
SSHLYRLRVIIPLGPAPSAAASDDQAQATASAAVAAAARTQHPPPKLGLPVPSSRWAGSGLSVERRPEDAPATGFGLVGD
TVREERYLQVLHPVPGVLARNADEVQRAYQEYQEKALGRTGLRKMYIGTLTLTLFLAVFIAVMLALLLGGQLARPLLMLL
QGTKEVAEGDLSPKRELKSRDELGMLTQQFNQMTRQLAEARIAVEENRSALEQSKAYLESVLRNLTAGVLVFDRRFVLIT
TNPGAERIFRQPLNGVLGHPVEQIPGMNDFAEIVRQAFSEQTTSEVLGGAQHWQKQIELPQGDEEQPLTLLVRGAHLPGG
SHDEPGYVVVFDDISDVISAQRSVAWGEVARRLAHEIKNPLTPIQLSAERLQMKLSPKLETSDAEVLKRGAATIVNQVAA
MKRMVDDFRDYARTPPAVMQSLPLNGLVSEVLHLYGIDDPAVHEHPVIHPTLDTDMPEIKGDPTQLRQVIHNLLQNAQDA
VAENVAAGRAAPHITLHTETVEYKDSAGEDRQAVKLSIADNGPGFAPRILSRAFEPYVTTKAKGTGLGLAMVKKIIDEHG
ARIEVRNRMNGTEIIGAQISILFVKLA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=392, Percent_Identity=26.7857142857143, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790300, Length=369, Percent_Identity=24.9322493224932, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89854; Mature: 89854

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNPWDSRFRRLLYRVVVGIIVFLALVLVGLLAGASANTEFFDRYFTLLFKINLVVGAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVLTVGALALTLWLRYRRGKFGTRLMSKLAVFFGVVGVLPGVLIYLVSLQFVSRSIESWF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRVETALEAGLNLGRSTIDSQLADLQGKARLMADQLTGSTGMATSLQLNRLREQYGVQE
HHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
AAIFTGSGRVLATASSSYASLVPDLPSGVLAEQARMAGGYAAVEGGTDPSTGDKPQPNVD
HEEEECCCCEEEECCCCHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC
SSHLYRLRVIIPLGPAPSAAASDDQAQATASAAVAAAARTQHPPPKLGLPVPSSRWAGSG
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LSVERRPEDAPATGFGLVGDTVREERYLQVLHPVPGVLARNADEVQRAYQEYQEKALGRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHH
GLRKMYIGTLTLTLFLAVFIAVMLALLLGGQLARPLLMLLQGTKEVAEGDLSPKRELKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHCH
DELGMLTQQFNQMTRQLAEARIAVEENRSALEQSKAYLESVLRNLTAGVLVFDRRFVLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEE
TNPGAERIFRQPLNGVLGHPVEQIPGMNDFAEIVRQAFSEQTTSEVLGGAQHWQKQIELP
CCCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
QGDEEQPLTLLVRGAHLPGGSHDEPGYVVVFDDISDVISAQRSVAWGEVARRLAHEIKNP
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTPIQLSAERLQMKLSPKLETSDAEVLKRGAATIVNQVAAMKRMVDDFRDYARTPPAVMQ
CCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SLPLNGLVSEVLHLYGIDDPAVHEHPVIHPTLDTDMPEIKGDPTQLRQVIHNLLQNAQDA
HCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAENVAAGRAAPHITLHTETVEYKDSAGEDRQAVKLSIADNGPGFAPRILSRAFEPYVTT
HHHHHHCCCCCCEEEEEECEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEC
KAKGTGLGLAMVKKIIDEHGARIEVRNRMNGTEIIGAQISILFVKLA
CCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEECCEEEEEEEEEC
>Mature Secondary Structure
MNGNPWDSRFRRLLYRVVVGIIVFLALVLVGLLAGASANTEFFDRYFTLLFKINLVVGAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVLTVGALALTLWLRYRRGKFGTRLMSKLAVFFGVVGVLPGVLIYLVSLQFVSRSIESWF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRVETALEAGLNLGRSTIDSQLADLQGKARLMADQLTGSTGMATSLQLNRLREQYGVQE
HHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
AAIFTGSGRVLATASSSYASLVPDLPSGVLAEQARMAGGYAAVEGGTDPSTGDKPQPNVD
HEEEECCCCEEEECCCCHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC
SSHLYRLRVIIPLGPAPSAAASDDQAQATASAAVAAAARTQHPPPKLGLPVPSSRWAGSG
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LSVERRPEDAPATGFGLVGDTVREERYLQVLHPVPGVLARNADEVQRAYQEYQEKALGRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHH
GLRKMYIGTLTLTLFLAVFIAVMLALLLGGQLARPLLMLLQGTKEVAEGDLSPKRELKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHCH
DELGMLTQQFNQMTRQLAEARIAVEENRSALEQSKAYLESVLRNLTAGVLVFDRRFVLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEE
TNPGAERIFRQPLNGVLGHPVEQIPGMNDFAEIVRQAFSEQTTSEVLGGAQHWQKQIELP
CCCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
QGDEEQPLTLLVRGAHLPGGSHDEPGYVVVFDDISDVISAQRSVAWGEVARRLAHEIKNP
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTPIQLSAERLQMKLSPKLETSDAEVLKRGAATIVNQVAAMKRMVDDFRDYARTPPAVMQ
CCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SLPLNGLVSEVLHLYGIDDPAVHEHPVIHPTLDTDMPEIKGDPTQLRQVIHNLLQNAQDA
HCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAENVAAGRAAPHITLHTETVEYKDSAGEDRQAVKLSIADNGPGFAPRILSRAFEPYVTT
HHHHHHCCCCCCEEEEEECEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEC
KAKGTGLGLAMVKKIIDEHGARIEVRNRMNGTEIIGAQISILFVKLA
CCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEECCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]