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The map label for this gene is putA [H]

Identifier: 94312420

GI number: 94312420

Start: 3774558

End: 3778520

Strand: Reverse

Name: putA [H]

Synonym: Rmet_3489

Alternate gene names: 94312420

Gene position: 3778520-3774558 (Counterclockwise)

Preceding gene: 94312421

Following gene: 94312419

Centisome position: 96.19

GC content: 67.5

Gene sequence:

>3963_bases
ATGGCCACCACCACCCTCGGCGTCAAGCTCGACGACGCATCGCGCGAACGCCTGAAGCGCGTTGCCCAGTCCATCGACCG
CACCCCGCACTGGCTGATCAAGCAGGCCATCTTCACGTACCTGGAACAGGTGGAACGCGGCCATCTGCCCCATGAAGCTG
GTGCCGGCGCGACTGCAGATACCGATGGCGCCGATGCTGGCGACGCGACGCAGGCCGATGCCGCGCCGCAACCTTTCCTC
GAATTCGCGCAGAGCGTCCAGCCTCAGTCGGTACTGCGCGCGGCCATCACGTCCGCCTACCGCCGTCCGGAAACCGAATG
TGTGCCGGTGCTGCTGGAGCAGGCGCGCCTGCCGCAGGCGCAGGCCGATGCCGCCATCAAGATGGCGCGAGCCCTGGCGG
CCCGGCTGCGTGAGCAGAAAGTAGGCAGCGGACGCGAGGGGCTGGTGCAGGGGCTGATCCAGGAGTTCTCGTTGTCGTCG
CAGGAAGGCGTGGCGCTGATGTGCCTGGCCGAAGCGCTGCTGCGCATCCCCGACAAGGCCACGCGCGATGCGCTGATCCG
CGACAAGATCAGCGGCGCCAACTGGCAATCACATCTGGGCCAGAGCCCGTCGCTGTTCGTCAACGCTGCCACCTGGGGCC
TGCTGCTGACCGGCCGGCTGGTGGCCACGCACACCGAAGCCGGACTGTCGAAGGCGCTGACGCGCATCATCGGCAAGGGC
GGCGAGCCGTTGATCCGCAAGGGCGTGGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTGACTGGCGAAACAATCTC
CGAGGCGCTGGCCAACGCGCGCAAGTACGAGGAAGAGGGCTTCCGTTACTCGTATGACATGCTCGGCGAAGCGGCGATGA
CCGAGGCCGATGCCCAGCGCTACCTGGCGTCCTACGAGCAGGCGATCCACGCGATCGGGCAGGCTTCGCGCGGCCGTGGC
ATCTACGAAGGCCCAGGCATCTCGATCAAGCTATCCGCGCTGCACCCGCGCTACAGCCGCGCGCAGCACGAGCGCGTGAT
CACCGAACTCTACGGTCGCCTGAAGAGCCTGACGATGCTGGCCCGCCAGTACGACATCGGTATCAACATCGACGCCGAGG
AAGCGGACCGCCTGGAAATCTCGCTCGACCTGCTTGAGCGGCTCTGCTTCGAGCCGGAGCTGGCCGGTTGGAACGGCATC
GGCTTCGTGGTGCAGGGCTATCAGAAGCGCTGCCCGTTCGTGATCGATTATCTGATCGACCTGGCGCGCCGTAGCCGGCA
TCGCCTGATGATCCGCCTGGTCAAGGGTGCGTACTGGGACAGCGAGATCAAGCGCGCCCAGGTCGACGGCCTGGAGGGCT
ACCCGGTCTACACGCGCAAGGTCTACACCGATGTGTCGTATGTGGCCTGCGCCCGCAAGCTGCTGTCGGTGCCCGACGCG
ATTTATCCACAGTTCGCCACCCACAACGCCCACACGCTGGCAGCCATCTACCAGATCGCCGGCCAGAACTATTACCCCGG
CCAGTACGAATTCCAGTGCCTGCATGGCATGGGCGAGCCGCTGTACGACCAGGTGGTCGGCCCGGTGGCGGATGGCAAAT
TCAACCGGCCGTGCCGGATCTACGCGCCGGTCGGCACCCACGAAACGCTGCTGGCATACCTGGTGCGCCGCCTGCTCGAG
AACGGCGCCAACACCTCGTTCGTGAACCGGATCGCCGACGAGACGATCGCGCTCGACGATCTCGTCGCTGACCCGGTGGC
CGTGGTCGAAACCATGCACAAGACAGAGGGCGTGCTTGGCCTGCCGCATCCGCGTATCCCGCAGCCGCGCGCGCTGTATG
GCAAATCGCGCGCCAATTCGGCCGGCATCGACCTGTCGAATGAACATCGGTTGGCGTCGCTGTCGTCCGCACTGCTGGCC
GGCACCAGCGAGACGCCGCGCGCGGAACCGCTGCTCGGCGCCGCAGTGGCGGGCACGGATGCCACGTCCGAGCCGGTACT
GAATCCGGCGGATCGTCGCGACGTAGTGGGGCAGGTCAGCGAGGCAACGCCGGCTGAGACCGAAGCCGCGCTTGTGGCCG
CCGTCAACGTGGCGCCGATCTGGCAGGCCACGCCGCCCGAAGTGCGTGCCGCCGCGCTGGAACGCGCCGCCGATCTGATG
GAAGCCCAGATGCAGTCGCTGATGGGCATCATCATGCGCGAGGCCGGCAAGACGTTTTCGAACGCCATCGCCGAAGTGCG
CGAGGCGGTCGACTTCCTGCGCTACTACGCGGTGCAGGTCCGCGCGTCGTTCTCGAACGATACCCATCGCCCCCTTGGTC
CGGTGGTCTGCATCAGCCCGTGGAATTTCCCGCTGGCGATCTTCACCGGCCAGGTGGCCGCCGCGCTGGCAGCCGGGAAT
CCGGTGCTGGCCAAGCCGGCCGAACAGACGCCGCTGATCGCCGCCGCCGCCGTGCGTCTGCTGCGCGACGCCGGTGTGCC
CGCAGCCGCGGTGCAATTGCTGCCGGGCCGGGGCGAGACCGTCGGCGCGGCGCTGGTAGGCGACGCCCGGGTCAAGGGCG
TGATGTTCACCGGCTCGACCGAAGTTGCCCGCCTCCTGCAACGCAACGTGGCGAGCCGTCTCGATGCCGCGGGCCGTCCG
ATTCCGCTGATCGCCGAGACGGGCGGGCAGAACGCGATGATCGTCGATTCCTCGGCGCTGGCCGAGCAGGTGGTGGGCGA
CGTGGTGACTTCGGCCTTCGATTCGGCCGGCCAGCGCTGTTCGGCGCTGCGCGTGCTGTGCCTGCAGGAAGACGTGGCCG
ACCGCATCCTGGAAATGCTCAAGGGTGCGATGGGTGAGTTGACGCTGGGCAACCCGGATCGCCTCTCCACTGACGTTGGT
CCTGTGATCGACGAGGAAGCGCGCGGCAATATCCTGCGCCATATCGAAGCGATGCGGGCCAAGGGCCGTCGTGTGCACCA
GGCCGACCCGGGCGCGGCGGACACGCCGGCCTGCCGCCATGGCACGTTCGTGCCGCCGACGCTGATCGAACTCGATTCGA
TCGCGGAGCTGAAGCGGGAGGTGTTCGGTCCGGTGTTGCATGTGGTGCGCTTCCCGCGAACCGCGCTGGACAAGCTGATC
GACCAGATCAATGGCACTGGGTATGGCCTGACGCTCGGCGTCCACACGCGGATCGACGAGACGATCGCGCACATCGTCGA
CCGCGCGGATGTGGGCAATCTCTATGTGAACCGGAATGTCGTCGGCGCCGTGGTGGGCGTGCAGCCATTCGGTGGCGAAG
GGCTGTCCGGCACGGGGCCGAAGGCGGGAGGGCCACTCTATCTGCACCGGCTGCTGTCGGTCTGCCCGCAGGATGCCGTG
GCGCGCGCCGTGCGTGCGTCGGATGCGACTGGTGGCGTGGCCGCCGCGCCGGTGTCGCCCGAACTGGCCGCGCTGAAGGC
CTGGGCGCAGGCGTCGCTGCCCGAGGTGGCCGAGGCCTGCGATCGCCTGGCCGCGGCATCGCCGTCGGGGCTCGGTGTGA
CGCTGCCGGGTCCTACCGGCGAGCGCAACACCTACTCGCTGCTGCCGCGCGAGCGTGTGCTTTGCCTCGCCCAGCAGGAG
TCCGATCTGGTGCTGCAACTGGCCGCCGTGCTGGCCGTCGGCAGCGAGGCGTTGTGCGTTGACACAGCGCAGACCAGGGC
CCTGTCTGAAAGGCTTCCCGCCGCAGTACAATCGCGCGTCCGCATGGTTTCCGACTGGACGTCGACGGATACGGCATTCG
ATGCCGTGCTGCACCACGGCGATTCCGACCAGCTTCGCACGGTTTGCGAGCAGGTGGCCACCCGCACTGGTCCGATCGTC
GGCGTGCAGGGCCTTGCGCACGGTGAACCGAATATCGCTCTGGAGCGTTTGTTGATCGAACGTTCGCTGTCCGTCAATAC
GGCGGCCGCGGGCGGCAATGCAAGTTTGATGACGATCGGCTGA

Upstream 100 bases:

>100_bases
GAGTAAGATCGCGCCAGTCCGGCTATCTGGCGGGTACGCACACGTGCGTATCGCCGGTGCAGCCAACCGATATTCCAAGA
TTCGCTGGAGAACCGATCAC

Downstream 100 bases:

>100_bases
GGCAGGCCTCGACCGTGGCGCGTCGCAGTGCGCGGCGGGGGCCGGTGATCCCGACCCCGTCGCAACCCAGGAACGGAGCG
GTGCTGCCAACGCCGGTCCG

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1320; Mature: 1319

Protein sequence:

>1320_residues
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLEQVERGHLPHEAGAGATADTDGADAGDATQADAAPQPFL
EFAQSVQPQSVLRAAITSAYRRPETECVPVLLEQARLPQAQADAAIKMARALAARLREQKVGSGREGLVQGLIQEFSLSS
QEGVALMCLAEALLRIPDKATRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGRLVATHTEAGLSKALTRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEEEGFRYSYDMLGEAAMTEADAQRYLASYEQAIHAIGQASRGRG
IYEGPGISIKLSALHPRYSRAQHERVITELYGRLKSLTMLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGI
GFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
IYPQFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYDQVVGPVADGKFNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADETIALDDLVADPVAVVETMHKTEGVLGLPHPRIPQPRALYGKSRANSAGIDLSNEHRLASLSSALLA
GTSETPRAEPLLGAAVAGTDATSEPVLNPADRRDVVGQVSEATPAETEAALVAAVNVAPIWQATPPEVRAAALERAADLM
EAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAVQVRASFSNDTHRPLGPVVCISPWNFPLAIFTGQVAAALAAGN
PVLAKPAEQTPLIAAAAVRLLRDAGVPAAAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARLLQRNVASRLDAAGRP
IPLIAETGGQNAMIVDSSALAEQVVGDVVTSAFDSAGQRCSALRVLCLQEDVADRILEMLKGAMGELTLGNPDRLSTDVG
PVIDEEARGNILRHIEAMRAKGRRVHQADPGAADTPACRHGTFVPPTLIELDSIAELKREVFGPVLHVVRFPRTALDKLI
DQINGTGYGLTLGVHTRIDETIAHIVDRADVGNLYVNRNVVGAVVGVQPFGGEGLSGTGPKAGGPLYLHRLLSVCPQDAV
ARAVRASDATGGVAAAPVSPELAALKAWAQASLPEVAEACDRLAAASPSGLGVTLPGPTGERNTYSLLPRERVLCLAQQE
SDLVLQLAAVLAVGSEALCVDTAQTRALSERLPAAVQSRVRMVSDWTSTDTAFDAVLHHGDSDQLRTVCEQVATRTGPIV
GVQGLAHGEPNIALERLLIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1320_residues
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLEQVERGHLPHEAGAGATADTDGADAGDATQADAAPQPFL
EFAQSVQPQSVLRAAITSAYRRPETECVPVLLEQARLPQAQADAAIKMARALAARLREQKVGSGREGLVQGLIQEFSLSS
QEGVALMCLAEALLRIPDKATRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGRLVATHTEAGLSKALTRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEEEGFRYSYDMLGEAAMTEADAQRYLASYEQAIHAIGQASRGRG
IYEGPGISIKLSALHPRYSRAQHERVITELYGRLKSLTMLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGI
GFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
IYPQFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYDQVVGPVADGKFNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADETIALDDLVADPVAVVETMHKTEGVLGLPHPRIPQPRALYGKSRANSAGIDLSNEHRLASLSSALLA
GTSETPRAEPLLGAAVAGTDATSEPVLNPADRRDVVGQVSEATPAETEAALVAAVNVAPIWQATPPEVRAAALERAADLM
EAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAVQVRASFSNDTHRPLGPVVCISPWNFPLAIFTGQVAAALAAGN
PVLAKPAEQTPLIAAAAVRLLRDAGVPAAAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARLLQRNVASRLDAAGRP
IPLIAETGGQNAMIVDSSALAEQVVGDVVTSAFDSAGQRCSALRVLCLQEDVADRILEMLKGAMGELTLGNPDRLSTDVG
PVIDEEARGNILRHIEAMRAKGRRVHQADPGAADTPACRHGTFVPPTLIELDSIAELKREVFGPVLHVVRFPRTALDKLI
DQINGTGYGLTLGVHTRIDETIAHIVDRADVGNLYVNRNVVGAVVGVQPFGGEGLSGTGPKAGGPLYLHRLLSVCPQDAV
ARAVRASDATGGVAAAPVSPELAALKAWAQASLPEVAEACDRLAAASPSGLGVTLPGPTGERNTYSLLPRERVLCLAQQE
SDLVLQLAAVLAVGSEALCVDTAQTRALSERLPAAVQSRVRMVSDWTSTDTAFDAVLHHGDSDQLRTVCEQVATRTGPIV
GVQGLAHGEPNIALERLLIERSLSVNTAAAGGNASLMTIG
>Mature_1319_residues
ATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLEQVERGHLPHEAGAGATADTDGADAGDATQADAAPQPFLE
FAQSVQPQSVLRAAITSAYRRPETECVPVLLEQARLPQAQADAAIKMARALAARLREQKVGSGREGLVQGLIQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGRLVATHTEAGLSKALTRIIGKGG
EPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEEEGFRYSYDMLGEAAMTEADAQRYLASYEQAIHAIGQASRGRGI
YEGPGISIKLSALHPRYSRAQHERVITELYGRLKSLTMLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIG
FVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYVACARKLLSVPDAI
YPQFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYDQVVGPVADGKFNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADETIALDDLVADPVAVVETMHKTEGVLGLPHPRIPQPRALYGKSRANSAGIDLSNEHRLASLSSALLAG
TSETPRAEPLLGAAVAGTDATSEPVLNPADRRDVVGQVSEATPAETEAALVAAVNVAPIWQATPPEVRAAALERAADLME
AQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAVQVRASFSNDTHRPLGPVVCISPWNFPLAIFTGQVAAALAAGNP
VLAKPAEQTPLIAAAAVRLLRDAGVPAAAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARLLQRNVASRLDAAGRPI
PLIAETGGQNAMIVDSSALAEQVVGDVVTSAFDSAGQRCSALRVLCLQEDVADRILEMLKGAMGELTLGNPDRLSTDVGP
VIDEEARGNILRHIEAMRAKGRRVHQADPGAADTPACRHGTFVPPTLIELDSIAELKREVFGPVLHVVRFPRTALDKLID
QINGTGYGLTLGVHTRIDETIAHIVDRADVGNLYVNRNVVGAVVGVQPFGGEGLSGTGPKAGGPLYLHRLLSVCPQDAVA
RAVRASDATGGVAAAPVSPELAALKAWAQASLPEVAEACDRLAAASPSGLGVTLPGPTGERNTYSLLPRERVLCLAQQES
DLVLQLAAVLAVGSEALCVDTAQTRALSERLPAAVQSRVRMVSDWTSTDTAFDAVLHHGDSDQLRTVCEQVATRTGPIVG
VQGLAHGEPNIALERLLIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=465, Percent_Identity=32.6881720430108, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI25777724, Length=464, Percent_Identity=30.8189655172414, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI153266822, Length=454, Percent_Identity=30.1762114537445, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI25777732, Length=457, Percent_Identity=30.8533916849015, Blast_Score=184, Evalue=7e-46,
Organism=Homo sapiens, GI25777736, Length=468, Percent_Identity=31.4102564102564, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI25777734, Length=468, Percent_Identity=31.4102564102564, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI238859541, Length=468, Percent_Identity=31.4102564102564, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI25777730, Length=464, Percent_Identity=30.3879310344828, Blast_Score=177, Evalue=7e-44,
Organism=Homo sapiens, GI25777728, Length=417, Percent_Identity=30.9352517985612, Blast_Score=174, Evalue=6e-43,
Organism=Homo sapiens, GI21614513, Length=502, Percent_Identity=27.8884462151394, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI12007648, Length=443, Percent_Identity=27.313769751693, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI4507229, Length=510, Percent_Identity=29.2156862745098, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI238814322, Length=429, Percent_Identity=26.8065268065268, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI188035924, Length=456, Percent_Identity=28.7280701754386, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=28.7280701754386, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI310128093, Length=456, Percent_Identity=28.2894736842105, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777726, Length=464, Percent_Identity=27.801724137931, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777721, Length=523, Percent_Identity=28.2982791586998, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI115387104, Length=480, Percent_Identity=26.0416666666667, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI11095441, Length=424, Percent_Identity=27.5943396226415, Blast_Score=136, Evalue=2e-31,
Organism=Homo sapiens, GI310128091, Length=391, Percent_Identity=29.923273657289, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI25952152, Length=253, Percent_Identity=31.6205533596838, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI71773324, Length=397, Percent_Identity=25.4408060453401, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI4502043, Length=421, Percent_Identity=24.7030878859857, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI238814371, Length=421, Percent_Identity=24.7030878859857, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI206597441, Length=430, Percent_Identity=25.1162790697674, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI206597439, Length=430, Percent_Identity=25.1162790697674, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI22907049, Length=430, Percent_Identity=25.1162790697674, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI310128087, Length=277, Percent_Identity=29.9638989169675, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310128089, Length=332, Percent_Identity=29.2168674698795, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI4557303, Length=341, Percent_Identity=26.6862170087977, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI73466520, Length=341, Percent_Identity=26.6862170087977, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=29.4303797468354, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI73695881, Length=331, Percent_Identity=24.773413897281, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI73695879, Length=331, Percent_Identity=24.773413897281, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI310128097, Length=260, Percent_Identity=30, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128101, Length=224, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI310128099, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI301500698, Length=439, Percent_Identity=22.7790432801822, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI223972651, Length=393, Percent_Identity=27.4809160305344, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787250, Length=1327, Percent_Identity=72.9464958553127, Blast_Score=1911, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=461, Percent_Identity=31.8872017353579, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI1787715, Length=465, Percent_Identity=32.258064516129, Blast_Score=176, Evalue=7e-45,
Organism=Escherichia coli, GI1788042, Length=440, Percent_Identity=31.8181818181818, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=29.2841648590022, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=30.7692307692308, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI87081896, Length=475, Percent_Identity=28.4210526315789, Blast_Score=146, Evalue=8e-36,
Organism=Escherichia coli, GI87082295, Length=483, Percent_Identity=27.7432712215321, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1786504, Length=467, Percent_Identity=26.7665952890792, Blast_Score=137, Evalue=6e-33,
Organism=Escherichia coli, GI87081926, Length=413, Percent_Identity=25.4237288135593, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1787653, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=464, Percent_Identity=31.0344827586207, Blast_Score=182, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144435, Length=455, Percent_Identity=31.4285714285714, Blast_Score=179, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=31.7073170731707, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=30.9734513274336, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=454, Percent_Identity=29.7356828193833, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=383, Percent_Identity=31.5926892950392, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=478, Percent_Identity=26.5690376569038, Blast_Score=152, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71986308, Length=463, Percent_Identity=27.645788336933, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI32564151, Length=411, Percent_Identity=28.2238442822384, Blast_Score=136, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25143874, Length=504, Percent_Identity=26.984126984127, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143876, Length=504, Percent_Identity=26.984126984127, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=452, Percent_Identity=25.2212389380531, Blast_Score=132, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=470, Percent_Identity=25.9574468085106, Blast_Score=126, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.1851015801354, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=26, Blast_Score=113, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=307, Percent_Identity=28.6644951140065, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32566756, Length=417, Percent_Identity=21.5827338129496, Blast_Score=90, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=417, Percent_Identity=21.5827338129496, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=417, Percent_Identity=21.5827338129496, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=334, Percent_Identity=24.5508982035928, Blast_Score=83, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=481, Percent_Identity=30.3534303534304, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6325196, Length=484, Percent_Identity=29.3388429752066, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6324950, Length=451, Percent_Identity=27.9379157427938, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=484, Percent_Identity=29.7520661157025, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=470, Percent_Identity=31.4893617021277, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=469, Percent_Identity=30.0639658848614, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=471, Percent_Identity=28.6624203821656, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321828, Length=512, Percent_Identity=23.6328125, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=330, Percent_Identity=24.8484848484848, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI20129399, Length=455, Percent_Identity=30.989010989011, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281362580, Length=488, Percent_Identity=29.7131147540984, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472918, Length=488, Percent_Identity=29.7131147540984, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472926, Length=488, Percent_Identity=29.7131147540984, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472936, Length=488, Percent_Identity=29.7131147540984, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21356737, Length=488, Percent_Identity=29.7131147540984, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24650465, Length=452, Percent_Identity=28.3185840707965, Blast_Score=174, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24668425, Length=470, Percent_Identity=28.936170212766, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24668417, Length=470, Percent_Identity=28.936170212766, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24668413, Length=470, Percent_Identity=28.936170212766, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24585660, Length=474, Percent_Identity=27.4261603375527, Blast_Score=158, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571806, Length=475, Percent_Identity=29.0526315789474, Blast_Score=150, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28571802, Length=475, Percent_Identity=29.0526315789474, Blast_Score=150, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28571800, Length=475, Percent_Identity=29.0526315789474, Blast_Score=150, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28571798, Length=475, Percent_Identity=29.0526315789474, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28571796, Length=475, Percent_Identity=29.0526315789474, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28571794, Length=475, Percent_Identity=29.0526315789474, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24666674, Length=450, Percent_Identity=29.5555555555556, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574525, Length=487, Percent_Identity=26.0780287474333, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24638876, Length=427, Percent_Identity=27.8688524590164, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24638878, Length=427, Percent_Identity=27.8688524590164, Blast_Score=114, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281360301, Length=351, Percent_Identity=27.3504273504274, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360299, Length=351, Percent_Identity=27.3504273504274, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360297, Length=351, Percent_Identity=27.3504273504274, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360295, Length=351, Percent_Identity=27.3504273504274, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24586250, Length=351, Percent_Identity=27.3504273504274, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45552499, Length=351, Percent_Identity=26.2108262108262, Blast_Score=94, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281360303, Length=351, Percent_Identity=26.2108262108262, Blast_Score=93, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 141259; Mature: 141127

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLEQVERGHLPHEAGAGATAD
CCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
TDGADAGDATQADAAPQPFLEFAQSVQPQSVLRAAITSAYRRPETECVPVLLEQARLPQA
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
QADAAIKMARALAARLREQKVGSGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIPDKA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHH
TRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGRLVATHTEAGLSKALTRIIGKG
HHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEEEGFRYSYDMLGEAAMTEADAQR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHH
YLASYEQAIHAIGQASRGRGIYEGPGISIKLSALHPRYSRAQHERVITELYGRLKSLTML
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIGFVVQGYQKRCPFVIDYLID
HHHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHHHHHHH
LARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHH
IYPQFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYDQVVGPVADGKFNRPCRI
HCCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADETIALDDLVADPVAVVETMHKTEGVLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
LPHPRIPQPRALYGKSRANSAGIDLSNEHRLASLSSALLAGTSETPRAEPLLGAAVAGTD
CCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
ATSEPVLNPADRRDVVGQVSEATPAETEAALVAAVNVAPIWQATPPEVRAAALERAADLM
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHH
EAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAVQVRASFSNDTHRPLGPVVCISP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEECC
WNFPLAIFTGQVAAALAAGNPVLAKPAEQTPLIAAAAVRLLRDAGVPAAAVQLLPGRGET
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCE
VGAALVGDARVKGVMFTGSTEVARLLQRNVASRLDAAGRPIPLIAETGGQNAMIVDSSAL
ECCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHH
AEQVVGDVVTSAFDSAGQRCSALRVLCLQEDVADRILEMLKGAMGELTLGNPDRLSTDVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVIDEEARGNILRHIEAMRAKGRRVHQADPGAADTPACRHGTFVPPTLIELDSIAELKRE
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VFGPVLHVVRFPRTALDKLIDQINGTGYGLTLGVHTRIDETIAHIVDRADVGNLYVNRNV
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCEEECCCC
VGAVVGVQPFGGEGLSGTGPKAGGPLYLHRLLSVCPQDAVARAVRASDATGGVAAAPVSP
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCH
ELAALKAWAQASLPEVAEACDRLAAASPSGLGVTLPGPTGERNTYSLLPRERVLCLAQQE
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCHHHHHEECCCC
SDLVLQLAAVLAVGSEALCVDTAQTRALSERLPAAVQSRVRMVSDWTSTDTAFDAVLHHG
CHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
DSDQLRTVCEQVATRTGPIVGVQGLAHGEPNIALERLLIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEC
>Mature Secondary Structure 
ATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLEQVERGHLPHEAGAGATAD
CCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
TDGADAGDATQADAAPQPFLEFAQSVQPQSVLRAAITSAYRRPETECVPVLLEQARLPQA
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
QADAAIKMARALAARLREQKVGSGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIPDKA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHH
TRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGRLVATHTEAGLSKALTRIIGKG
HHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEEEGFRYSYDMLGEAAMTEADAQR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHH
YLASYEQAIHAIGQASRGRGIYEGPGISIKLSALHPRYSRAQHERVITELYGRLKSLTML
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIGFVVQGYQKRCPFVIDYLID
HHHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHHHHHHH
LARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHH
IYPQFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYDQVVGPVADGKFNRPCRI
HCCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADETIALDDLVADPVAVVETMHKTEGVLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
LPHPRIPQPRALYGKSRANSAGIDLSNEHRLASLSSALLAGTSETPRAEPLLGAAVAGTD
CCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
ATSEPVLNPADRRDVVGQVSEATPAETEAALVAAVNVAPIWQATPPEVRAAALERAADLM
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHH
EAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAVQVRASFSNDTHRPLGPVVCISP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEECC
WNFPLAIFTGQVAAALAAGNPVLAKPAEQTPLIAAAAVRLLRDAGVPAAAVQLLPGRGET
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCE
VGAALVGDARVKGVMFTGSTEVARLLQRNVASRLDAAGRPIPLIAETGGQNAMIVDSSAL
ECCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHH
AEQVVGDVVTSAFDSAGQRCSALRVLCLQEDVADRILEMLKGAMGELTLGNPDRLSTDVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVIDEEARGNILRHIEAMRAKGRRVHQADPGAADTPACRHGTFVPPTLIELDSIAELKRE
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VFGPVLHVVRFPRTALDKLIDQINGTGYGLTLGVHTRIDETIAHIVDRADVGNLYVNRNV
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCEEECCCC
VGAVVGVQPFGGEGLSGTGPKAGGPLYLHRLLSVCPQDAVARAVRASDATGGVAAAPVSP
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCH
ELAALKAWAQASLPEVAEACDRLAAASPSGLGVTLPGPTGERNTYSLLPRERVLCLAQQE
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCHHHHHEECCCC
SDLVLQLAAVLAVGSEALCVDTAQTRALSERLPAAVQSRVRMVSDWTSTDTAFDAVLHHG
CHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
DSDQLRTVCEQVATRTGPIVGVQGLAHGEPNIALERLLIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]