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The map label for this gene is dsbC [H]

Identifier: 94312121

GI number: 94312121

Start: 3465301

End: 3466059

Strand: Reverse

Name: dsbC [H]

Synonym: Rmet_3190

Alternate gene names: 94312121

Gene position: 3466059-3465301 (Counterclockwise)

Preceding gene: 94312122

Following gene: 94312120

Centisome position: 88.24

GC content: 63.11

Gene sequence:

>759_bases
ATGTTCCAAATGTTCCGCCGCCGTTCCGCTCGCTTCGCCGCAATCGCGGCTCTGGCAAGCGGCGTGGGCGCCGCCGGCTA
TGCCCTGCACGCGCTGGCCGCGGACGAGCCGGGCACGGATCGCATCAAGGCGTCGATCCAGAAGATCCTGGGTGGCCGCG
CCGAGGTCAAGAGCGTGACCAAGGCGCCGGTGCCAGGCCTGTACGAAGTCAACGTCAGCGGCCAGCTTGTCTATACCGAC
GCCACCGGTCGCTACATCATCAACGGCGAACTGATCGACACCAAGACCAACACGAACCTGACCGAGGAGCGTCTGGCCGA
GTTGAACAAGATCAAGTGGTCGGATCTGCCGCTGTCGCGCGCCATCAAGTGGACCAAGGGTGACGGCAGCCGCACCGTGG
CGGTGTTCTCGGACCCGAACTGCGGCTACTGCAAGAAGATCGAGCAGACCTTCCAGCAGATGGACAACATCACGGTCTAC
ACCTTCCTCTATCCGGTGCTGTCGCCGGATTCCACGGTGAAGGCAAAGCAGGTGTGGTGCTCGGCCGATCGCACCAAGGT
CTGGCGCGACTGGATGCTGAACCACGTGGCGCTCACCGGCAACGGATCCTGCAAGACGCCGGTCGATGAGAACCTCGAGC
TTGGCCACAACCTGAACATCACGGGCACGCCGGCGGTGTTCTTCTCCGATGGCACGCGAATCCCTGGAGCCGCTGACGCG
GCCACGCTGGAACGCAAGCTCGCCAGCCTGAAAAAATAA

Upstream 100 bases:

>100_bases
GAGGCGAATCCACAAACGAGCCACAAACCAGCCCATTAACGATTTACCATTCACGAACAAGCCGGCACACTGACCGGCGC
ATCGTTTTCCTGGAGTCACT

Downstream 100 bases:

>100_bases
GACCGACGCCGGACCCCATCCGGCTGTATGAAGCGGCCGGTTGCTACCGGCCGCTTTGCATTTCCGCGCCCCGGATTGAT
TTCGAAAACGACGACGAAAA

Product: Protein-disulfide isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFQMFRRRSARFAAIAALASGVGAAGYALHALAADEPGTDRIKASIQKILGGRAEVKSVTKAPVPGLYEVNVSGQLVYTD
ATGRYIINGELIDTKTNTNLTEERLAELNKIKWSDLPLSRAIKWTKGDGSRTVAVFSDPNCGYCKKIEQTFQQMDNITVY
TFLYPVLSPDSTVKAKQVWCSADRTKVWRDWMLNHVALTGNGSCKTPVDENLELGHNLNITGTPAVFFSDGTRIPGAADA
ATLERKLASLKK

Sequences:

>Translated_252_residues
MFQMFRRRSARFAAIAALASGVGAAGYALHALAADEPGTDRIKASIQKILGGRAEVKSVTKAPVPGLYEVNVSGQLVYTD
ATGRYIINGELIDTKTNTNLTEERLAELNKIKWSDLPLSRAIKWTKGDGSRTVAVFSDPNCGYCKKIEQTFQQMDNITVY
TFLYPVLSPDSTVKAKQVWCSADRTKVWRDWMLNHVALTGNGSCKTPVDENLELGHNLNITGTPAVFFSDGTRIPGAADA
ATLERKLASLKK
>Mature_252_residues
MFQMFRRRSARFAAIAALASGVGAAGYALHALAADEPGTDRIKASIQKILGGRAEVKSVTKAPVPGLYEVNVSGQLVYTD
ATGRYIINGELIDTKTNTNLTEERLAELNKIKWSDLPLSRAIKWTKGDGSRTVAVFSDPNCGYCKKIEQTFQQMDNITVY
TFLYPVLSPDSTVKAKQVWCSADRTKVWRDWMLNHVALTGNGSCKTPVDENLELGHNLNITGTPAVFFSDGTRIPGAADA
ATLERKLASLKK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=202, Percent_Identity=29.2079207920792, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 27530; Mature: 27530

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQMFRRRSARFAAIAALASGVGAAGYALHALAADEPGTDRIKASIQKILGGRAEVKSVT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHH
KAPVPGLYEVNVSGQLVYTDATGRYIINGELIDTKTNTNLTEERLAELNKIKWSDLPLSR
CCCCCCEEEECCCCEEEEEECCCCEEEECEEEECCCCCCCHHHHHHHHHCCCCCCCCHHH
AIKWTKGDGSRTVAVFSDPNCGYCKKIEQTFQQMDNITVYTFLYPVLSPDSTVKAKQVWC
CEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHH
SADRTKVWRDWMLNHVALTGNGSCKTPVDENLELGHNLNITGTPAVFFSDGTRIPGAADA
CCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHH
ATLERKLASLKK
HHHHHHHHHHCC
>Mature Secondary Structure
MFQMFRRRSARFAAIAALASGVGAAGYALHALAADEPGTDRIKASIQKILGGRAEVKSVT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHH
KAPVPGLYEVNVSGQLVYTDATGRYIINGELIDTKTNTNLTEERLAELNKIKWSDLPLSR
CCCCCCEEEECCCCEEEEEECCCCEEEECEEEECCCCCCCHHHHHHHHHCCCCCCCCHHH
AIKWTKGDGSRTVAVFSDPNCGYCKKIEQTFQQMDNITVYTFLYPVLSPDSTVKAKQVWC
CEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHH
SADRTKVWRDWMLNHVALTGNGSCKTPVDENLELGHNLNITGTPAVFFSDGTRIPGAADA
CCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHH
ATLERKLASLKK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]