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The map label for this gene is 94312029

Identifier: 94312029

GI number: 94312029

Start: 3357350

End: 3358231

Strand: Reverse

Name: 94312029

Synonym: Rmet_3098

Alternate gene names: NA

Gene position: 3358231-3357350 (Counterclockwise)

Preceding gene: 94312030

Following gene: 94312028

Centisome position: 85.49

GC content: 65.87

Gene sequence:

>882_bases
ATGAAGCGCGATTCCCGCGCGGGGTACTGTGCGTCTTCGCCCGAGTTGGAGCACTGGCTGACACGCCATATCGCGCAAGG
CTTCGATGCCGAGTCGCTGGTGCTGTCGATGCTGCGCTCCGGCTACGACGCCGCGTTCGCACGCCATGCTGTCAGCGCTG
CAATAGGGCATCCTCCGGCCGTTGCCAGTGCGGCAGCGCCCGCGCCCGTAGCGAAGGCCGCTGCAACGCCAACGGTCACC
GGTGGCAATGCCTTCCGCCACAAGGATCGCGAGATGCCGATCCTGTTCAGGCTGGACTCGCCGCGCATCCTGTTGCTGCA
GAACCTGCTCGATGACGCCGAATGCGATGCCGTCGTGGCGCTGGCGCGCGACCGCCTGCAGCGCTCTCCCGTGGTCAATC
CGGACACTGGCGACGAGAACCTGATCGATGCGCGTACCAGCATGGGCGCGATGTTCCAGGTTGGCGAACATGCGCTGCTG
CAACGCATCGAGGCGCGTATCGCGGCCGTGACCGGCTGGCCCGTCGAGCACGGCGAAGGCTTTCAGGTCCTCAACTACAA
GCCCGGCGGCGAGTATCAGCCGCATTTCGATTTCTTCAATCCCAAGCGTCCCGGCGAAGCGCGCCAGTTGCGCGTGGGCG
GGCAGCGCGTTGCCACGATGGTGATCTACCTGAACAGTCCGGCCTCTGGTGGTGCCACGGCATTCCCGCGCATCGGCCTC
GAGGTGGCGCCGGTGAAGGGCAATGCGGTCCTGTTCAGCTACGGCCTGCCCGATGGCGCGCTCGACGAGCGCACCTTGCA
CGCGGGATTGCCGGTGGAGGCGGGCGAAAAATGGATCGCTACTAAATGGCTGCGCGAGCATCCATACCGCAGCAGGGGCT
GA

Upstream 100 bases:

>100_bases
GCCGCGGTCACCCCGGCACCCGTGCGACGCGCGGTGCCGCCGGAGTCGCCCGCCCGCAATCCGTTCTCGCCGCAACGTCT
TGCCAATCCGTCATGAAGTC

Downstream 100 bases:

>100_bases
ACTTGCATTCGTGCGGTAGCTGAATTACCCGCCTTTGCGTGCTCATGATTTTCCTATAATTCGTAGAATTGCCAGATATA
TCTGATCGATGATTATTGAT

Product: prolyl 4-hydroxylase

Products: NA

Alternate protein names: 2OG-Fe(II) Oxygenase; Prolyl 4-Hydroxylase Alpha Subunit; Oxidoreductase 2OG-Fe(II) Oxygenase Family; Oxygenase; Procollagen-Proline 2-Oxoglutarate-4-Dioxygenase; Response Regulator Receiver Domain-Containing Protein; 2OG-Fe(II) Oxygenase Family Oxidoreductase; Prolyl 4-Hydroxylase Subunit Alpha; 2OG-Fe(II) Oxygenase Superfamily Protein; 2OG-Fe(II) Oxygenase Family Protein; Procollagen-Proline 2-Oxoglutarate-4- Dioxygenase; Prolyl 4-Hydroxylase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKRDSRAGYCASSPELEHWLTRHIAQGFDAESLVLSMLRSGYDAAFARHAVSAAIGHPPAVASAAAPAPVAKAAATPTVT
GGNAFRHKDREMPILFRLDSPRILLLQNLLDDAECDAVVALARDRLQRSPVVNPDTGDENLIDARTSMGAMFQVGEHALL
QRIEARIAAVTGWPVEHGEGFQVLNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRVATMVIYLNSPASGGATAFPRIGL
EVAPVKGNAVLFSYGLPDGALDERTLHAGLPVEAGEKWIATKWLREHPYRSRG

Sequences:

>Translated_293_residues
MKRDSRAGYCASSPELEHWLTRHIAQGFDAESLVLSMLRSGYDAAFARHAVSAAIGHPPAVASAAAPAPVAKAAATPTVT
GGNAFRHKDREMPILFRLDSPRILLLQNLLDDAECDAVVALARDRLQRSPVVNPDTGDENLIDARTSMGAMFQVGEHALL
QRIEARIAAVTGWPVEHGEGFQVLNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRVATMVIYLNSPASGGATAFPRIGL
EVAPVKGNAVLFSYGLPDGALDERTLHAGLPVEAGEKWIATKWLREHPYRSRG
>Mature_293_residues
MKRDSRAGYCASSPELEHWLTRHIAQGFDAESLVLSMLRSGYDAAFARHAVSAAIGHPPAVASAAAPAPVAKAAATPTVT
GGNAFRHKDREMPILFRLDSPRILLLQNLLDDAECDAVVALARDRLQRSPVVNPDTGDENLIDARTSMGAMFQVGEHALL
QRIEARIAAVTGWPVEHGEGFQVLNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRVATMVIYLNSPASGGATAFPRIGL
EVAPVKGNAVLFSYGLPDGALDERTLHAGLPVEAGEKWIATKWLREHPYRSRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI217272849, Length=188, Percent_Identity=40.4255319148936, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI63252888, Length=188, Percent_Identity=40.4255319148936, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI63252886, Length=188, Percent_Identity=39.8936170212766, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI63252893, Length=188, Percent_Identity=36.1702127659575, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI63252891, Length=188, Percent_Identity=36.1702127659575, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI217272861, Length=188, Percent_Identity=36.1702127659575, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI4758868, Length=188, Percent_Identity=35.6382978723404, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI217272863, Length=188, Percent_Identity=35.6382978723404, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI33589818, Length=191, Percent_Identity=40.8376963350785, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI217272851, Length=188, Percent_Identity=34.0425531914894, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17541712, Length=193, Percent_Identity=36.7875647668394, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17552840, Length=190, Percent_Identity=33.1578947368421, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193209070, Length=139, Percent_Identity=30.2158273381295, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193209068, Length=136, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72000637, Length=114, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550388, Length=188, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651477, Length=187, Percent_Identity=36.8983957219251, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24651407, Length=186, Percent_Identity=34.4086021505376, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI116008432, Length=259, Percent_Identity=31.6602316602317, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI116008128, Length=253, Percent_Identity=31.6205533596838, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24651418, Length=188, Percent_Identity=36.1702127659575, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24651424, Length=185, Percent_Identity=35.6756756756757, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281362877, Length=202, Percent_Identity=32.1782178217822, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281361323, Length=198, Percent_Identity=32.3232323232323, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI221460681, Length=147, Percent_Identity=40.1360544217687, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651430, Length=189, Percent_Identity=31.2169312169312, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI116008434, Length=198, Percent_Identity=30.3030303030303, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI116008130, Length=185, Percent_Identity=32.4324324324324, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI116008537, Length=185, Percent_Identity=32.4324324324324, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78706702, Length=193, Percent_Identity=30.5699481865285, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651420, Length=188, Percent_Identity=35.6382978723404, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358233, Length=189, Percent_Identity=31.7460317460317, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45550650, Length=193, Percent_Identity=25.9067357512953, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221512818, Length=129, Percent_Identity=37.2093023255814, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358309, Length=118, Percent_Identity=36.4406779661017, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24651416, Length=185, Percent_Identity=29.1891891891892, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221512810, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24666354, Length=125, Percent_Identity=32.8, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31746; Mature: 31746

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDSRAGYCASSPELEHWLTRHIAQGFDAESLVLSMLRSGYDAAFARHAVSAAIGHPPA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCH
VASAAAPAPVAKAAATPTVTGGNAFRHKDREMPILFRLDSPRILLLQNLLDDAECDAVVA
HHHCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHH
LARDRLQRSPVVNPDTGDENLIDARTSMGAMFQVGEHALLQRIEARIAAVTGWPVEHGEG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
FQVLNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRVATMVIYLNSPASGGATAFPRIGL
EEEEEECCCCCCCCCCCCCCCCCCCCHHEEECCCCEEEEEEEEEECCCCCCCCCCCCCCE
EVAPVKGNAVLFSYGLPDGALDERTLHAGLPVEAGEKWIATKWLREHPYRSRG
EEEECCCCEEEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRDSRAGYCASSPELEHWLTRHIAQGFDAESLVLSMLRSGYDAAFARHAVSAAIGHPPA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCH
VASAAAPAPVAKAAATPTVTGGNAFRHKDREMPILFRLDSPRILLLQNLLDDAECDAVVA
HHHCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHH
LARDRLQRSPVVNPDTGDENLIDARTSMGAMFQVGEHALLQRIEARIAAVTGWPVEHGEG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
FQVLNYKPGGEYQPHFDFFNPKRPGEARQLRVGGQRVATMVIYLNSPASGGATAFPRIGL
EEEEEECCCCCCCCCCCCCCCCCCCCHHEEECCCCEEEEEEEEEECCCCCCCCCCCCCCE
EVAPVKGNAVLFSYGLPDGALDERTLHAGLPVEAGEKWIATKWLREHPYRSRG
EEEECCCCEEEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA