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The map label for this gene is tnpAB [C]

Identifier: 94311923

GI number: 94311923

Start: 3247826

End: 3249364

Strand: Reverse

Name: tnpAB [C]

Synonym: Rmet_2991

Alternate gene names: 94311923

Gene position: 3249364-3247826 (Counterclockwise)

Preceding gene: 94311924

Following gene: 94311922

Centisome position: 82.72

GC content: 52.44

Gene sequence:

>1539_bases
ATGTACTCATACGCAGACAGGATTCGTGCAGTTGCGCTTTACATCAAGCTTGGCTTGCGTGTCAGAGCCACGATTCGCCA
GTTGGGGTACCCAACCAAGAACGCATTGAAAGGCTGGTATCAGCACTACCTGAAGCATCAGGATTTGCCAGCAAGCCAAG
CTCCAAGAGCACCAAAATATTCGCTGCAGCAAAGGCAGGTGGCTATTGCTCATTACCTCGCCCATGATCGCTGTATTGCT
GCAACGATGAGGGCTTTGGGTTATCCGGGTCGAGGAACGTTGACTGCGTGGGTTCGGCAAGACTGCCCTGACACCTGCAA
ATCGAGAGTAGGCAGATCTTGGCCGGCTACAAAGCCTGATGCCTTGATGTGTGAGGGCGTGGTGCAGCTGTGTGCCCGTC
GATCAAGTGCACAGCAGATTGCGGACAAGTTAGGGGTGTGTAGGGGGACCTTGTACAACTGGAAAAATCAGTTGCTTGGC
CCTTGTGCCCCAGCCTCAATGAAACACAGTCCAAAGCGATCGCCAGTGTTGGATGAAGCAGCACTCAGGCGCCAAGTTGA
ATCATTGCGCCAGGATGTTCGGCGGCTGAAGATAGAACGTGAGCTTCTCAAGCAGGCCCATGAAATCTTAAAAAATGGGG
CTGACATTGATCTGCATAGGCTGGCAAACAAAGATAAGGCTGTGCTGGTTGAAGCGTTGCACGGGCAGTATGAATTGCCA
GAACTGCTTTCTCTTGTTGGCCTTGCTAGAAGCTCGTATTTTTACCATCGTGCTCGGCTGAAGCTGGCTGACAAATACGT
TGATTTACGCCGAAGCATCACAGAGATCTTCGACAACAACTACCGTTGCTATGGATATCGCAGGGTGCAGGCATCTCTGC
TCAAGGAGTGCACGGGCATCTCAGAGAAGGTGGTTCGTCGGCTGATGAAGCAGGAGGGGTTGATCGTGGCCAAGCCCAAA
CGCCGCAGATATAACTCCTACCTTGGAGAGATAGGTGCCGCCCCGCAAAACCTCATCAATCGAGACTTCCGTGCCGCTGC
GCCCAATGAGAAGTGGCTCACCGACATTACTGAACTCCAGATTCCTGCTGGCAAGGTTTACCTGTCGCCAGTCATTGATT
GCTTTGACGGGCTGGTGGTGAGCTGGTCGATTGGGACTCATCCCAACGCACATCTCGTCAACACAATGCTGGATGCGGCC
ATTGATGCTGTTCAAGGCAGCGAGAGCCGCCCTGTGATTCATTCTGATCGTGGAGCTCACTACCGCTGGCCAGGCTGGCT
CTCGAGGGTCCATGATGCAAAGTTGACTCGCTCGATGTCTCGCAAAGGGTGCTCACCAGACAACGCTGCGTGCGAAGGCT
TTTTTGGAAGGCTAAAGATGGAGCTGTTCTATCCCAACAACTGGCAATCAACAACGATTGAGCAGTTCATTGAAGCTGTC
GATGCGTACATTCGTTGGTACAACGAAAAACGTATCAAGGTATCTCTGGGACGTTTAAGTCCTGTGGAATACCGGCACAA
ACTTGGCCTAGCCGCATAA

Upstream 100 bases:

>100_bases
TGCTTTGATGCATCTCAATGAATCTAGGCTGTTGATTTCCACGCAGAACTGACCCGCCGGGGATGCGGACAAAAACTTGG
ACTACCAGGGGAGGTAGTTC

Downstream 100 bases:

>100_bases
AACCAGTCCAAGTTTTTATCCGCACCCCCACCGGGGGCTAGTGGGTCACTTCTGGGTGGAAATCAACACGCTGTTCAAGC
CGGGGCTGAAGTTCGAACCC

Product: transposase ISRme17

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MYSYADRIRAVALYIKLGLRVRATIRQLGYPTKNALKGWYQHYLKHQDLPASQAPRAPKYSLQQRQVAIAHYLAHDRCIA
ATMRALGYPGRGTLTAWVRQDCPDTCKSRVGRSWPATKPDALMCEGVVQLCARRSSAQQIADKLGVCRGTLYNWKNQLLG
PCAPASMKHSPKRSPVLDEAALRRQVESLRQDVRRLKIERELLKQAHEILKNGADIDLHRLANKDKAVLVEALHGQYELP
ELLSLVGLARSSYFYHRARLKLADKYVDLRRSITEIFDNNYRCYGYRRVQASLLKECTGISEKVVRRLMKQEGLIVAKPK
RRRYNSYLGEIGAAPQNLINRDFRAAAPNEKWLTDITELQIPAGKVYLSPVIDCFDGLVVSWSIGTHPNAHLVNTMLDAA
IDAVQGSESRPVIHSDRGAHYRWPGWLSRVHDAKLTRSMSRKGCSPDNAACEGFFGRLKMELFYPNNWQSTTIEQFIEAV
DAYIRWYNEKRIKVSLGRLSPVEYRHKLGLAA

Sequences:

>Translated_512_residues
MYSYADRIRAVALYIKLGLRVRATIRQLGYPTKNALKGWYQHYLKHQDLPASQAPRAPKYSLQQRQVAIAHYLAHDRCIA
ATMRALGYPGRGTLTAWVRQDCPDTCKSRVGRSWPATKPDALMCEGVVQLCARRSSAQQIADKLGVCRGTLYNWKNQLLG
PCAPASMKHSPKRSPVLDEAALRRQVESLRQDVRRLKIERELLKQAHEILKNGADIDLHRLANKDKAVLVEALHGQYELP
ELLSLVGLARSSYFYHRARLKLADKYVDLRRSITEIFDNNYRCYGYRRVQASLLKECTGISEKVVRRLMKQEGLIVAKPK
RRRYNSYLGEIGAAPQNLINRDFRAAAPNEKWLTDITELQIPAGKVYLSPVIDCFDGLVVSWSIGTHPNAHLVNTMLDAA
IDAVQGSESRPVIHSDRGAHYRWPGWLSRVHDAKLTRSMSRKGCSPDNAACEGFFGRLKMELFYPNNWQSTTIEQFIEAV
DAYIRWYNEKRIKVSLGRLSPVEYRHKLGLAA
>Mature_512_residues
MYSYADRIRAVALYIKLGLRVRATIRQLGYPTKNALKGWYQHYLKHQDLPASQAPRAPKYSLQQRQVAIAHYLAHDRCIA
ATMRALGYPGRGTLTAWVRQDCPDTCKSRVGRSWPATKPDALMCEGVVQLCARRSSAQQIADKLGVCRGTLYNWKNQLLG
PCAPASMKHSPKRSPVLDEAALRRQVESLRQDVRRLKIERELLKQAHEILKNGADIDLHRLANKDKAVLVEALHGQYELP
ELLSLVGLARSSYFYHRARLKLADKYVDLRRSITEIFDNNYRCYGYRRVQASLLKECTGISEKVVRRLMKQEGLIVAKPK
RRRYNSYLGEIGAAPQNLINRDFRAAAPNEKWLTDITELQIPAGKVYLSPVIDCFDGLVVSWSIGTHPNAHLVNTMLDAA
IDAVQGSESRPVIHSDRGAHYRWPGWLSRVHDAKLTRSMSRKGCSPDNAACEGFFGRLKMELFYPNNWQSTTIEQFIEAV
DAYIRWYNEKRIKVSLGRLSPVEYRHKLGLAA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=248, Percent_Identity=28.2258064516129, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1789981, Length=279, Percent_Identity=42.2939068100358, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788405, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787263, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786753, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786570, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786490, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 58295; Mature: 58295

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSYADRIRAVALYIKLGLRVRATIRQLGYPTKNALKGWYQHYLKHQDLPASQAPRAPKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
SLQQRQVAIAHYLAHDRCIAATMRALGYPGRGTLTAWVRQDCPDTCKSRVGRSWPATKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCH
ALMCEGVVQLCARRSSAQQIADKLGVCRGTLYNWKNQLLGPCAPASMKHSPKRSPVLDEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
ALRRQVESLRQDVRRLKIERELLKQAHEILKNGADIDLHRLANKDKAVLVEALHGQYELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCCCCHH
ELLSLVGLARSSYFYHRARLKLADKYVDLRRSITEIFDNNYRCYGYRRVQASLLKECTGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCC
SEKVVRRLMKQEGLIVAKPKRRRYNSYLGEIGAAPQNLINRDFRAAAPNEKWLTDITELQ
HHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHC
IPAGKVYLSPVIDCFDGLVVSWSIGTHPNAHLVNTMLDAAIDAVQGSESRPVIHSDRGAH
CCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
YRWPGWLSRVHDAKLTRSMSRKGCSPDNAACEGFFGRLKMELFYPNNWQSTTIEQFIEAV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHH
DAYIRWYNEKRIKVSLGRLSPVEYRHKLGLAA
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure
MYSYADRIRAVALYIKLGLRVRATIRQLGYPTKNALKGWYQHYLKHQDLPASQAPRAPKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
SLQQRQVAIAHYLAHDRCIAATMRALGYPGRGTLTAWVRQDCPDTCKSRVGRSWPATKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCH
ALMCEGVVQLCARRSSAQQIADKLGVCRGTLYNWKNQLLGPCAPASMKHSPKRSPVLDEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
ALRRQVESLRQDVRRLKIERELLKQAHEILKNGADIDLHRLANKDKAVLVEALHGQYELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCCCCHH
ELLSLVGLARSSYFYHRARLKLADKYVDLRRSITEIFDNNYRCYGYRRVQASLLKECTGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCC
SEKVVRRLMKQEGLIVAKPKRRRYNSYLGEIGAAPQNLINRDFRAAAPNEKWLTDITELQ
HHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHC
IPAGKVYLSPVIDCFDGLVVSWSIGTHPNAHLVNTMLDAAIDAVQGSESRPVIHSDRGAH
CCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
YRWPGWLSRVHDAKLTRSMSRKGCSPDNAACEGFFGRLKMELFYPNNWQSTTIEQFIEAV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHH
DAYIRWYNEKRIKVSLGRLSPVEYRHKLGLAA
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]