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The map label for this gene is cbbT2 [H]

Identifier: 94311912

GI number: 94311912

Start: 3238831

End: 3240810

Strand: Reverse

Name: cbbT2 [H]

Synonym: Rmet_2980

Alternate gene names: 94311912

Gene position: 3240810-3238831 (Counterclockwise)

Preceding gene: 94311917

Following gene: 94311911

Centisome position: 82.5

GC content: 65.76

Gene sequence:

>1980_bases
ATGGCGGATGCCATCCGCGTGCTTGCCATGGACGCTGTCCAGCAAGCCAACTCCGGTCACCCCGGTGCGCCGATGGGTAT
GGCCGATATGGCCGTGGCGCTGTGGGGCCGGCATCTGAAGCATAACCCCGTCAATCCGCACTGGCCTGACCGCGACCGCT
TCGTGCTGTCCAACGGCCACGGATCGATGCTGATCTACGCGCTGCTGCACCTGACCGGCTATGACCTGCCGATCGAGGAA
CTGAAGAACTTCCGCCAGTTGCACAGCAAGACCGCCGGCCACCCGGAGTATGGCATTACCCCGGGCGTGGAAACCACGAC
CGGCCCGCTGGGCCAGGGCATCACCAATGCCGTCGGCATGGCGCTGGCCGAGCGCCTGCTGGGCGAGGAATTCAACCGCC
CGGGTTTCGACATCGTCAACCACCACACGTACGTGTTCATGGGCGATGGCTGCCTGATGGAAGGCATCAGCCATGAAGCC
TGCTCGCTGGCCGGCACGCTCAAGCTGAACAAGCTGATCGGCTTCTGGGATGACAACGGCATCTCCATCGATGGCGACGT
GGTGCACTGGTTTGCCGACGATACGCCGAAGCGTTTCGAAGCCTATGGCTGGAACGTGATCCGCGCCGTGGACGGCCACG
ACGTGGCTGCCGTCGACAACGCCATCGCGCTGGCCAAGGCCAGCGACAAGCCGACCCTGATCTGCTGCCGCACCGTCATC
GGCAAGGGTGCGCCGAACAAGGCCGGCGGCCACGACGTGCATGGCGCGCCGCTGGGCGGCGCCGAAGTGCTGGCCACCCG
CGAAGCGCTGGGCTGGACCCACGCCCCGTTCGAAGTGCCGCAGGACGCGTACCTCGCCTGGGACGCGAAGCCGAACGGCC
ACGCGCTGGAAAAGGCCTGGGACGCACTGTTCGACGCCTACGCCGAAGTGCATCCGTACGAAGCCGGTGAGTTCAAGCGC
CGCGTGCGCGGCGAGCTGCCGGGCGCGTTCGATGCGGCCGTGGACGCCTACATCGCCAAGTGCGAGGAGAAGGCCGAGAC
GATCGCTACCCGCAAGGCCAGCCAGAACTCGATCGAGGCACTGGCGCCGGTACTGCCGGAACTGCTGGGCGGCTCGGCCG
ACCTGACCGGTTCGAACCTGACCAACTGGTCGGGCACGCAGGCCGTTCGCTTCGACTCGTGGGGCAACCACATCAACTAC
GGTGTGCGTGAGTTCGGCATGAGCGCGATCATGAACGGCATCGCGCTGCATGGTGGCTACATCCCCTACGGCGCCACGTT
CCTGACGTTCTCGGACTACAGTCGCAACGCGTTGCGCATGGCCGCGCTGATGAAGATCCGCTCGCTGTTTGTGTTCACGC
ATGATTCGATCGGCCTGGGCGAAGACGGTCCGACCCACCAGTCGATCGAGCACGTGGCCAGCCTGCGTCTGATCCCGAAC
ATGGATGTCTGGCGTACCGCCGACACCACCGAGACTGCAGTGGCCTGGGCGCAGTCGATCCGCCGCGAGAACGGTCCGAG
CTGCCTGATTTTCAGCCGCCAGAACTTGCCGTTCCAGAAGCGTGACGATGTCACGCGCGCCAATATCGCGCGCGGTGGCT
ACGTGCTGCGCGATGGCACGAATCCGCGCAAGAAGCGCCCGGATGCCGTGATTATCGCCACCGGCTCGGAAGTCGGCCTG
GCCGTGGGCGCCGCCGATGCGCTGGCCGTGGAAGGCGTGCACGTGCGCGTGGTGTCGGTTCCGTCGACCTCCGTCTTTGA
CAAGCAGGACGCCGCCTACAAGGCCAGCGTGCTGCCGGCAGGCGTGCCGCGCATCGCCGTGGAAGCGGGCGTCACCGATT
TCTGGTGGAAGTACCAGGTTCAGGCCGTCGTCGGTATCGACACGTTCGGCGAATCGGCCCCGGCAGGCGTGCTGTTCAAG
CACTTCGGCTTCACCGTGGAAAACGTGGCCGATACGGTGCGCGCCACGCTCGCCCAGTAA

Upstream 100 bases:

>100_bases
TGCTTCTGCTAAAATTGCGGTTTTCCCGCCGTCAGGTTCTCGCATGTCTGCCCTCGCCCATCCCGCCACAAGTCCTTACG
CCAACCAACCCGTCAAACTG

Downstream 100 bases:

>100_bases
TTCTCGCCAGCGCGGTATGCCGGCGCGAGGCGCCGGCTGCGGCGCCGGCCCCAGCTTTATCGCGATTGCACTCTAGGAGA
TAGACATGACCATCAAGATC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MADAIRVLAMDAVQQANSGHPGAPMGMADMAVALWGRHLKHNPVNPHWPDRDRFVLSNGHGSMLIYALLHLTGYDLPIEE
LKNFRQLHSKTAGHPEYGITPGVETTTGPLGQGITNAVGMALAERLLGEEFNRPGFDIVNHHTYVFMGDGCLMEGISHEA
CSLAGTLKLNKLIGFWDDNGISIDGDVVHWFADDTPKRFEAYGWNVIRAVDGHDVAAVDNAIALAKASDKPTLICCRTVI
GKGAPNKAGGHDVHGAPLGGAEVLATREALGWTHAPFEVPQDAYLAWDAKPNGHALEKAWDALFDAYAEVHPYEAGEFKR
RVRGELPGAFDAAVDAYIAKCEEKAETIATRKASQNSIEALAPVLPELLGGSADLTGSNLTNWSGTQAVRFDSWGNHINY
GVREFGMSAIMNGIALHGGYIPYGATFLTFSDYSRNALRMAALMKIRSLFVFTHDSIGLGEDGPTHQSIEHVASLRLIPN
MDVWRTADTTETAVAWAQSIRRENGPSCLIFSRQNLPFQKRDDVTRANIARGGYVLRDGTNPRKKRPDAVIIATGSEVGL
AVGAADALAVEGVHVRVVSVPSTSVFDKQDAAYKASVLPAGVPRIAVEAGVTDFWWKYQVQAVVGIDTFGESAPAGVLFK
HFGFTVENVADTVRATLAQ

Sequences:

>Translated_659_residues
MADAIRVLAMDAVQQANSGHPGAPMGMADMAVALWGRHLKHNPVNPHWPDRDRFVLSNGHGSMLIYALLHLTGYDLPIEE
LKNFRQLHSKTAGHPEYGITPGVETTTGPLGQGITNAVGMALAERLLGEEFNRPGFDIVNHHTYVFMGDGCLMEGISHEA
CSLAGTLKLNKLIGFWDDNGISIDGDVVHWFADDTPKRFEAYGWNVIRAVDGHDVAAVDNAIALAKASDKPTLICCRTVI
GKGAPNKAGGHDVHGAPLGGAEVLATREALGWTHAPFEVPQDAYLAWDAKPNGHALEKAWDALFDAYAEVHPYEAGEFKR
RVRGELPGAFDAAVDAYIAKCEEKAETIATRKASQNSIEALAPVLPELLGGSADLTGSNLTNWSGTQAVRFDSWGNHINY
GVREFGMSAIMNGIALHGGYIPYGATFLTFSDYSRNALRMAALMKIRSLFVFTHDSIGLGEDGPTHQSIEHVASLRLIPN
MDVWRTADTTETAVAWAQSIRRENGPSCLIFSRQNLPFQKRDDVTRANIARGGYVLRDGTNPRKKRPDAVIIATGSEVGL
AVGAADALAVEGVHVRVVSVPSTSVFDKQDAAYKASVLPAGVPRIAVEAGVTDFWWKYQVQAVVGIDTFGESAPAGVLFK
HFGFTVENVADTVRATLAQ
>Mature_658_residues
ADAIRVLAMDAVQQANSGHPGAPMGMADMAVALWGRHLKHNPVNPHWPDRDRFVLSNGHGSMLIYALLHLTGYDLPIEEL
KNFRQLHSKTAGHPEYGITPGVETTTGPLGQGITNAVGMALAERLLGEEFNRPGFDIVNHHTYVFMGDGCLMEGISHEAC
SLAGTLKLNKLIGFWDDNGISIDGDVVHWFADDTPKRFEAYGWNVIRAVDGHDVAAVDNAIALAKASDKPTLICCRTVIG
KGAPNKAGGHDVHGAPLGGAEVLATREALGWTHAPFEVPQDAYLAWDAKPNGHALEKAWDALFDAYAEVHPYEAGEFKRR
VRGELPGAFDAAVDAYIAKCEEKAETIATRKASQNSIEALAPVLPELLGGSADLTGSNLTNWSGTQAVRFDSWGNHINYG
VREFGMSAIMNGIALHGGYIPYGATFLTFSDYSRNALRMAALMKIRSLFVFTHDSIGLGEDGPTHQSIEHVASLRLIPNM
DVWRTADTTETAVAWAQSIRRENGPSCLIFSRQNLPFQKRDDVTRANIARGGYVLRDGTNPRKKRPDAVIIATGSEVGLA
VGAADALAVEGVHVRVVSVPSTSVFDKQDAAYKASVLPAGVPRIAVEAGVTDFWWKYQVQAVVGIDTFGESAPAGVLFKH
FGFTVENVADTVRATLAQ

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=600, Percent_Identity=26.3333333333333, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI4507521, Length=600, Percent_Identity=26.3333333333333, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI133778974, Length=582, Percent_Identity=26.1168384879725, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI225637459, Length=260, Percent_Identity=25.3846153846154, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI48994911, Length=661, Percent_Identity=64.9016641452345, Blast_Score=896, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=60.8169440242057, Blast_Score=826, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=597, Percent_Identity=24.7906197654941, Blast_Score=142, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6325331, Length=669, Percent_Identity=49.3273542600897, Blast_Score=592, Evalue=1e-170,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=45.059880239521, Blast_Score=538, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24645119, Length=670, Percent_Identity=27.1641791044776, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45551847, Length=278, Percent_Identity=34.8920863309352, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45550715, Length=278, Percent_Identity=34.8920863309352, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666278, Length=262, Percent_Identity=33.206106870229, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71088; Mature: 70957

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAIRVLAMDAVQQANSGHPGAPMGMADMAVALWGRHLKHNPVNPHWPDRDRFVLSNGH
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
GSMLIYALLHLTGYDLPIEELKNFRQLHSKTAGHPEYGITPGVETTTGPLGQGITNAVGM
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALAERLLGEEFNRPGFDIVNHHTYVFMGDGCLMEGISHEACSLAGTLKLNKLIGFWDDNG
HHHHHHHHHHCCCCCCEEECCEEEEEECCCHHHCCCCHHHHHHHHHEEEEEEEEEECCCC
ISIDGDVVHWFADDTPKRFEAYGWNVIRAVDGHDVAAVDNAIALAKASDKPTLICCRTVI
EEECCCEEEEECCCCCHHHHHCCCEEEEEECCCCEEHHCCEEEEEECCCCCEEEEEEHHH
GKGAPNKAGGHDVHGAPLGGAEVLATREALGWTHAPFEVPQDAYLAWDAKPNGHALEKAW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
DALFDAYAEVHPYEAGEFKRRVRGELPGAFDAAVDAYIAKCEEKAETIATRKASQNSIEA
HHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LAPVLPELLGGSADLTGSNLTNWSGTQAVRFDSWGNHINYGVREFGMSAIMNGIALHGGY
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
IPYGATFLTFSDYSRNALRMAALMKIRSLFVFTHDSIGLGEDGPTHQSIEHVASLRLIPN
CCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHEEECCC
MDVWRTADTTETAVAWAQSIRRENGPSCLIFSRQNLPFQKRDDVTRANIARGGYVLRDGT
CCCEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCEEEECCC
NPRKKRPDAVIIATGSEVGLAVGAADALAVEGVHVRVVSVPSTSVFDKQDAAYKASVLPA
CCCCCCCCEEEEECCCCCCEEECCCCCEEECCEEEEEEECCCCCCCCCCCCCCEEECCCC
GVPRIAVEAGVTDFWWKYQVQAVVGIDTFGESAPAGVLFKHFGFTVENVADTVRATLAQ
CCCCEEEECCCCHHEEEEEEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADAIRVLAMDAVQQANSGHPGAPMGMADMAVALWGRHLKHNPVNPHWPDRDRFVLSNGH
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
GSMLIYALLHLTGYDLPIEELKNFRQLHSKTAGHPEYGITPGVETTTGPLGQGITNAVGM
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALAERLLGEEFNRPGFDIVNHHTYVFMGDGCLMEGISHEACSLAGTLKLNKLIGFWDDNG
HHHHHHHHHHCCCCCCEEECCEEEEEECCCHHHCCCCHHHHHHHHHEEEEEEEEEECCCC
ISIDGDVVHWFADDTPKRFEAYGWNVIRAVDGHDVAAVDNAIALAKASDKPTLICCRTVI
EEECCCEEEEECCCCCHHHHHCCCEEEEEECCCCEEHHCCEEEEEECCCCCEEEEEEHHH
GKGAPNKAGGHDVHGAPLGGAEVLATREALGWTHAPFEVPQDAYLAWDAKPNGHALEKAW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
DALFDAYAEVHPYEAGEFKRRVRGELPGAFDAAVDAYIAKCEEKAETIATRKASQNSIEA
HHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LAPVLPELLGGSADLTGSNLTNWSGTQAVRFDSWGNHINYGVREFGMSAIMNGIALHGGY
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
IPYGATFLTFSDYSRNALRMAALMKIRSLFVFTHDSIGLGEDGPTHQSIEHVASLRLIPN
CCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHEEECCC
MDVWRTADTTETAVAWAQSIRRENGPSCLIFSRQNLPFQKRDDVTRANIARGGYVLRDGT
CCCEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCEEEECCC
NPRKKRPDAVIIATGSEVGLAVGAADALAVEGVHVRVVSVPSTSVFDKQDAAYKASVLPA
CCCCCCCCEEEEECCCCCCEEECCCCCEEECCEEEEEEECCCCCCCCCCCCCCEEECCCC
GVPRIAVEAGVTDFWWKYQVQAVVGIDTFGESAPAGVLFKHFGFTVENVADTVRATLAQ
CCCCEEEECCCCHHEEEEEEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8241274; 9278503; 2153656 [H]