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The map label for this gene is cbbG2 [H]

Identifier: 94311911

GI number: 94311911

Start: 3237747

End: 3238745

Strand: Reverse

Name: cbbG2 [H]

Synonym: Rmet_2979

Alternate gene names: 94311911

Gene position: 3238745-3237747 (Counterclockwise)

Preceding gene: 94311912

Following gene: 335055640

Centisome position: 82.45

GC content: 61.86

Gene sequence:

>999_bases
ATGACCATCAAGATCGGCATCAACGGCTTTGGCCGCATCGGGCGCATGGTGTTCCGCGCCGCCGCCGCGAACTTCAAGGA
CATTGAAGTCGTCGCCATCAACGACCTGCTGGAACCGGACTACCTGGCGTACATGCTGAAGTACGACTCGGTCCACGGCC
GCTTCGACGGCGAAGTGTCGGTGGAAGGCAACACGCTCGTGGTCAACGGCAAGAAGATCCGCCTGACCGCCGTCAAGGAT
CCGTCCGAGCTGAAGTGGGGCGAAGTCGGCGCCGACGTGGTGATCGAGTCGACCGGCATCTTCCTGACGAAGGAAGGCGC
GCAGAAGCACATCGACGCGGGCGCCAAGAAGGTGATCATGTCGGCCCCGTCGAAGGACGACACCCCGATGTTCGTGTTCG
GCGTGAACCACGAGACGTACAAGGGCGAAGCGATCATCTCGAACGCAAGCTGCACGACCAACTGCCTGGCCCCGGTGGCA
AAGGTCCTGAACGACAAGTGGGGCATCAAGCGCGGCCTGATGACGACCGTGCACGCTGCCACCGCCACGCAGAAGACCGT
GGATGGTCCGTCGAACAAGGACTGGCGCGGTGGCCGTGGCATCCTGGAAAACATCATCCCGTCGTCGACTGGCGCCGCCA
AGGCCGTTGGCGTGGTGATTCCGCAGCTGAACAAGAAGCTGACCGGTATGTCGTTCCGCGTGCCGACCTCGGACGTTTCG
GTGGTCGACCTGACCGTCGAACTGGAAAACCCGGCCAAGTACGAAGAAATCTGCGCCGAGATGAAGGCCCAGAGCCAGGG
CGCGCTGAAGGGCGTGCTGGGCTACACCGAAGACAAGGTTGTGGCCACGGACTTCCGCGGTGATGCCCGCACCTCGATTT
TCGATGCTGAAGCCGGTATCGCGCTGGACGGCACGTTCATCAAGGTCGTGAGCTGGTACGACAACGAGTGGGGCTATTCG
AACAAGTGCCTGGAAATGGCACGCGTCGTGGCCAAGTAA

Upstream 100 bases:

>100_bases
ACGCTCGCCCAGTAATTCTCGCCAGCGCGGTATGCCGGCGCGAGGCGCCGGCTGCGGCGCCGGCCCCAGCTTTATCGCGA
TTGCACTCTAGGAGATAGAC

Downstream 100 bases:

>100_bases
GCCATCCTCGCTGAACAAAAAACGCGCCCTCGGGCGCGTTTTTTGTTGCTCAGGCGGCAGGTGGGGTGACTGGTGGCGTT
AGCGGCCGCGCATCGATAGC

Product: glyceraldehyde-3-phosphate dehydrogenase A

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTIKIGINGFGRIGRMVFRAAAANFKDIEVVAINDLLEPDYLAYMLKYDSVHGRFDGEVSVEGNTLVVNGKKIRLTAVKD
PSELKWGEVGADVVIESTGIFLTKEGAQKHIDAGAKKVIMSAPSKDDTPMFVFGVNHETYKGEAIISNASCTTNCLAPVA
KVLNDKWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPQLNKKLTGMSFRVPTSDVS
VVDLTVELENPAKYEEICAEMKAQSQGALKGVLGYTEDKVVATDFRGDARTSIFDAEAGIALDGTFIKVVSWYDNEWGYS
NKCLEMARVVAK

Sequences:

>Translated_332_residues
MTIKIGINGFGRIGRMVFRAAAANFKDIEVVAINDLLEPDYLAYMLKYDSVHGRFDGEVSVEGNTLVVNGKKIRLTAVKD
PSELKWGEVGADVVIESTGIFLTKEGAQKHIDAGAKKVIMSAPSKDDTPMFVFGVNHETYKGEAIISNASCTTNCLAPVA
KVLNDKWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPQLNKKLTGMSFRVPTSDVS
VVDLTVELENPAKYEEICAEMKAQSQGALKGVLGYTEDKVVATDFRGDARTSIFDAEAGIALDGTFIKVVSWYDNEWGYS
NKCLEMARVVAK
>Mature_331_residues
TIKIGINGFGRIGRMVFRAAAANFKDIEVVAINDLLEPDYLAYMLKYDSVHGRFDGEVSVEGNTLVVNGKKIRLTAVKDP
SELKWGEVGADVVIESTGIFLTKEGAQKHIDAGAKKVIMSAPSKDDTPMFVFGVNHETYKGEAIISNASCTTNCLAPVAK
VLNDKWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPQLNKKLTGMSFRVPTSDVSV
VDLTVELENPAKYEEICAEMKAQSQGALKGVLGYTEDKVVATDFRGDARTSIFDAEAGIALDGTFIKVVSWYDNEWGYSN
KCLEMARVVAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=60.960960960961, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=56.5349544072948, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=70.1807228915663, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=39.7014925373134, Blast_Score=258, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=60.5970149253731, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=60.5970149253731, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=60.4166666666667, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=60.4166666666667, Blast_Score=399, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=61.144578313253, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=60.8433734939759, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=60.5421686746988, Blast_Score=406, Evalue=1e-114,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=59.3272171253823, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=59.3272171253823, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19922412, Length=324, Percent_Identity=61.1111111111111, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=59.3272171253823, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=59.3272171253823, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35830; Mature: 35699

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIGINGFGRIGRMVFRAAAANFKDIEVVAINDLLEPDYLAYMLKYDSVHGRFDGEVS
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCCEEE
VEGNTLVVNGKKIRLTAVKDPSELKWGEVGADVVIESTGIFLTKEGAQKHIDAGAKKVIM
ECCCEEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEECCCCHHHHCCCCCEEEE
SAPSKDDTPMFVFGVNHETYKGEAIISNASCTTNCLAPVAKVLNDKWGIKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPQLNKKLTGMSFRVPTSDVS
HCCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHEEEEEECCCCCCCCCCEEECCCCCCE
VVDLTVELENPAKYEEICAEMKAQSQGALKGVLGYTEDKVVATDFRGDARTSIFDAEAGI
EEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCCEEEECCCCE
ALDGTFIKVVSWYDNEWGYSNKCLEMARVVAK
EECCEEEEEEEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TIKIGINGFGRIGRMVFRAAAANFKDIEVVAINDLLEPDYLAYMLKYDSVHGRFDGEVS
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCCEEE
VEGNTLVVNGKKIRLTAVKDPSELKWGEVGADVVIESTGIFLTKEGAQKHIDAGAKKVIM
ECCCEEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEECCCCHHHHCCCCCEEEE
SAPSKDDTPMFVFGVNHETYKGEAIISNASCTTNCLAPVAKVLNDKWGIKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPQLNKKLTGMSFRVPTSDVS
HCCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHEEEEEECCCCCCCCCCEEECCCCCCE
VVDLTVELENPAKYEEICAEMKAQSQGALKGVLGYTEDKVVATDFRGDARTSIFDAEAGI
EEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCCEEEECCCCE
ALDGTFIKVVSWYDNEWGYSNKCLEMARVVAK
EECCEEEEEEEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]