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The map label for this gene is ubiA

Identifier: 94311871

GI number: 94311871

Start: 3193762

End: 3194646

Strand: Reverse

Name: ubiA

Synonym: Rmet_2939

Alternate gene names: 94311871

Gene position: 3194646-3193762 (Counterclockwise)

Preceding gene: 94311872

Following gene: 94311868

Centisome position: 81.33

GC content: 64.41

Gene sequence:

>885_bases
ATGTCCCATCCCTCCACCGCCCCCGCCCACCCGAGCCGTCTGGCGCTATACGCGCGCCTGGTTCGCATCGACAAGCCGAT
TGGCACGCTGCTGTTGCTATGGCCCACGCTCTGGGCCATGTGGATGGCCGCCGGCGGGCCGCCGGGATGGACCCTGTTCT
GGATCTTCTTCGCTGGCACGTTCCTGATGCGTTCGGCCGGTTGCGCCATGAACGATTGGGCCGACCGCGATTTTGACAAG
CACGTGAAACGCACGAAGGAGCGGCCGCTGACCGCCGGGCTGATTGCCAGCTGGGAAGCGCTGGCCGTGGCGGCGGTGCT
GGCGCTGATCGCGCTGGCGCTGATTCTGCCGTTGAATGCGCTGACCAAATGGCTGGCCGTGGTGGCCGCCGTCCTGGCGG
GAACCTATCCGTTCTTCAAGCGGTTTTTCGCGATCCCGCAAGCGTACCTGGGTATCGCATTCGGCTTCGGCATCCCGATG
GCCTTCGCGGCGATCCAGGATCAGGTGCCGTTCGTGGCCTGGCTGATGCTGCTGGCCAATGTGTTCTGGGCGATTGCCTA
TGACACCGCATACGCGATGGTCGATCGCGATGACGACCTGCTGCTGGGCATGAAGACGTCGGCGATCACGTTTGGCCGGT
TCGACGTGGCCGCGATCATGATCTGCTACGCCGTCTTCCTGGGTTTGATGGCCTGGGCAGGATCGCTGCTCGGACTGGGC
TGGCCGTACTATGCCGGCCTGGTGGCAGCCGCGGGGATGGCGGGCTATCACTACACGCTGATTCGCGAGCGCGACCGCAT
GAAGTGTTTCGCGGCCTTCCGGCACAACAACTGGCTGGGTGCCTGCGTGTTCGCCGGGACGTTCGTGGCGTATCTGCTGA
AGTAA

Upstream 100 bases:

>100_bases
GTCACCGGTTGCCACGTCGCTTGCGGCAACCGGGCCAACGCGTCACGGTCCAACTGGCCGCGGCGCGTTTTTGTTTGAGT
CTTGCCAGAAGTACGCCGCC

Downstream 100 bases:

>100_bases
GAAACCGGGGCCAGGCCCCGGTTTTTTCTTAGTCCTTCCCGAACTCCGCTCCCATCTCGCGGCCCCGCGCGGCGGCGGCC
AGCATGGCGCGAACGAAGGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSHPSTAPAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAAGGPPGWTLFWIFFAGTFLMRSAGCAMNDWADRDFDK
HVKRTKERPLTAGLIASWEALAVAAVLALIALALILPLNALTKWLAVVAAVLAGTYPFFKRFFAIPQAYLGIAFGFGIPM
AFAAIQDQVPFVAWLMLLANVFWAIAYDTAYAMVDRDDDLLLGMKTSAITFGRFDVAAIMICYAVFLGLMAWAGSLLGLG
WPYYAGLVAAAGMAGYHYTLIRERDRMKCFAAFRHNNWLGACVFAGTFVAYLLK

Sequences:

>Translated_294_residues
MSHPSTAPAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAAGGPPGWTLFWIFFAGTFLMRSAGCAMNDWADRDFDK
HVKRTKERPLTAGLIASWEALAVAAVLALIALALILPLNALTKWLAVVAAVLAGTYPFFKRFFAIPQAYLGIAFGFGIPM
AFAAIQDQVPFVAWLMLLANVFWAIAYDTAYAMVDRDDDLLLGMKTSAITFGRFDVAAIMICYAVFLGLMAWAGSLLGLG
WPYYAGLVAAAGMAGYHYTLIRERDRMKCFAAFRHNNWLGACVFAGTFVAYLLK
>Mature_293_residues
SHPSTAPAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAAGGPPGWTLFWIFFAGTFLMRSAGCAMNDWADRDFDKH
VKRTKERPLTAGLIASWEALAVAAVLALIALALILPLNALTKWLAVVAAVLAGTYPFFKRFFAIPQAYLGIAFGFGIPMA
FAAIQDQVPFVAWLMLLANVFWAIAYDTAYAMVDRDDDLLLGMKTSAITFGRFDVAAIMICYAVFLGLMAWAGSLLGLGW
PYYAGLVAAAGMAGYHYTLIRERDRMKCFAAFRHNNWLGACVFAGTFVAYLLK

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=286, Percent_Identity=36.3636363636364, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1790473, Length=280, Percent_Identity=51.0714285714286, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1786631, Length=186, Percent_Identity=24.7311827956989, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553718, Length=290, Percent_Identity=35.8620689655172, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI32565247, Length=290, Percent_Identity=35.1724137931034, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=347, Percent_Identity=30.5475504322767, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=44.8275862068966, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=141, Percent_Identity=44.6808510638298, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=275, Percent_Identity=31.6363636363636, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355567, Length=286, Percent_Identity=36.3636363636364, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_RALME (Q1LJ64)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_585081.1
- STRING:   Q1LJ64
- GeneID:   4039767
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2939
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- PhylomeDB:   Q1LJ64
- ProtClustDB:   PRK12848
- BioCyc:   RMET266264:RMET_2939-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32411; Mature: 32280

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16ef2df8)-; HASH(0x1907f9c8)-; HASH(0x1907f908)-; HASH(0x18d35044)-; HASH(0x190c19f0)-; HASH(0x1883d9c0)-; HASH(0x18d32b10)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPSTAPAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAAGGPPGWTLFWIFFAGT
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FLMRSAGCAMNDWADRDFDKHVKRTKERPLTAGLIASWEALAVAAVLALIALALILPLNA
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTKWLAVVAAVLAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAIQDQVPFVAWLMLLAN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VFWAIAYDTAYAMVDRDDDLLLGMKTSAITFGRFDVAAIMICYAVFLGLMAWAGSLLGLG
HHHHHHHHHHHHEECCCCCEEEEEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WPYYAGLVAAAGMAGYHYTLIRERDRMKCFAAFRHNNWLGACVFAGTFVAYLLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
SHPSTAPAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAAGGPPGWTLFWIFFAGT
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FLMRSAGCAMNDWADRDFDKHVKRTKERPLTAGLIASWEALAVAAVLALIALALILPLNA
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTKWLAVVAAVLAGTYPFFKRFFAIPQAYLGIAFGFGIPMAFAAIQDQVPFVAWLMLLAN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VFWAIAYDTAYAMVDRDDDLLLGMKTSAITFGRFDVAAIMICYAVFLGLMAWAGSLLGLG
HHHHHHHHHHHHEECCCCCEEEEEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WPYYAGLVAAAGMAGYHYTLIRERDRMKCFAAFRHNNWLGACVFAGTFVAYLLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA