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The map label for this gene is dgk [H]

Identifier: 94311848

GI number: 94311848

Start: 3170266

End: 3170907

Strand: Direct

Name: dgk [H]

Synonym: Rmet_2916

Alternate gene names: 94311848

Gene position: 3170266-3170907 (Clockwise)

Preceding gene: 94311847

Following gene: 94311849

Centisome position: 80.71

GC content: 64.49

Gene sequence:

>642_bases
ATGCTCGATCATCTGCGTCGTATTGTCATCGAAGGCCCGGTCGGCTCCGGCAAGGCCGCGCTGGCCCAACGCCTGGCGCG
CCATCTCCAGGCGGCCGAACTCCCCGATGGCGCGCGCAACAACCCCTTCCTCGAACGCTTCTACCGCGAACCACAGCGCT
ATGCGCTGGCGATGCAGCTCGCCTGCCTGAACCAGCGCGTGACCCAGCTCCAGCAGTGGCATTCGGCGATGCTGGCCGGC
CAGCGCATGATCGGCAACTTCCTGTTTGCGCGCGACCGTGTCTACGCTTCGCTGACACTCGAAGCTGACGAACTCGCGCT
CTACGACGCGCTGGCGGCACGCCTGCAAGCGCCAGCGCAGCGCGTGGATCTGGTCATCATGCTGCAGGCCACGCCCTCGC
TGCTGCGTGAGCGAATCGCGCGGCGCGGCCTGCCCGGCGAGAGCGGTATCGACGAGCAATATCTGCAGCGGCTCACCGAT
GCCTATGGCGAGTTGTTCCACCGCTACGACGAAGCCCCGGTGCTGATCGTCGATACCGCACATTTCAACCCGGTAGACAA
CGACGTCGATTTCCGTACACTACTGTCGCGCATCGAGAACATGCGAGGCCGCAGGGCCTTTCTGAATCTCGTAGCGTCCT
GA

Upstream 100 bases:

>100_bases
TGCAAGAACAGCGCATCGAGAAGTTTTCCTCATGCAAATGCTCGCGCATGAAGGAAGGCGACGGCGCGCGGCCATGAGCG
CGCCACGCCGCGGCTGACAC

Downstream 100 bases:

>100_bases
GTCGTCCCGACGCGTCTGTCGAGCCGTTTCCACACGTGAAGCGGCTTTCGCCAGGCAGCACAACACACGAAAAAGACAGC
GGTCGACCCTGGCCATCCGA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MLDHLRRIVIEGPVGSGKAALAQRLARHLQAAELPDGARNNPFLERFYREPQRYALAMQLACLNQRVTQLQQWHSAMLAG
QRMIGNFLFARDRVYASLTLEADELALYDALAARLQAPAQRVDLVIMLQATPSLLRERIARRGLPGESGIDEQYLQRLTD
AYGELFHRYDEAPVLIVDTAHFNPVDNDVDFRTLLSRIENMRGRRAFLNLVAS

Sequences:

>Translated_213_residues
MLDHLRRIVIEGPVGSGKAALAQRLARHLQAAELPDGARNNPFLERFYREPQRYALAMQLACLNQRVTQLQQWHSAMLAG
QRMIGNFLFARDRVYASLTLEADELALYDALAARLQAPAQRVDLVIMLQATPSLLRERIARRGLPGESGIDEQYLQRLTD
AYGELFHRYDEAPVLIVDTAHFNPVDNDVDFRTLLSRIENMRGRRAFLNLVAS
>Mature_213_residues
MLDHLRRIVIEGPVGSGKAALAQRLARHLQAAELPDGARNNPFLERFYREPQRYALAMQLACLNQRVTQLQQWHSAMLAG
QRMIGNFLFARDRVYASLTLEADELALYDALAARLQAPAQRVDLVIMLQATPSLLRERIARRGLPGESGIDEQYLQRLTD
AYGELFHRYDEAPVLIVDTAHFNPVDNDVDFRTLLSRIENMRGRRAFLNLVAS

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24210; Mature: 24210

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDHLRRIVIEGPVGSGKAALAQRLARHLQAAELPDGARNNPFLERFYREPQRYALAMQL
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ACLNQRVTQLQQWHSAMLAGQRMIGNFLFARDRVYASLTLEADELALYDALAARLQAPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHCCHH
RVDLVIMLQATPSLLRERIARRGLPGESGIDEQYLQRLTDAYGELFHRYDEAPVLIVDTA
HHCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HFNPVDNDVDFRTLLSRIENMRGRRAFLNLVAS
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MLDHLRRIVIEGPVGSGKAALAQRLARHLQAAELPDGARNNPFLERFYREPQRYALAMQL
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ACLNQRVTQLQQWHSAMLAGQRMIGNFLFARDRVYASLTLEADELALYDALAARLQAPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHCCHH
RVDLVIMLQATPSLLRERIARRGLPGESGIDEQYLQRLTDAYGELFHRYDEAPVLIVDTA
HHCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HFNPVDNDVDFRTLLSRIENMRGRRAFLNLVAS
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]