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The map label for this gene is argD [H]

Identifier: 94311794

GI number: 94311794

Start: 3111836

End: 3113023

Strand: Direct

Name: argD [H]

Synonym: Rmet_2862

Alternate gene names: 94311794

Gene position: 3111836-3113023 (Clockwise)

Preceding gene: 94311793

Following gene: 94311802

Centisome position: 79.22

GC content: 63.72

Gene sequence:

>1188_bases
ATGGCATTTGCTGAGTTTCCCGTCCAATCCCTGATGTACATCACCAACCGGCCCGAACTGGTTTTCACCGAAGGCAAGGG
CTCTTGGCTGACGGACCATAACGGCAAGCGCTATCTCGATTTCGTGCAGGGTTGGGCGGTCAACGCACTGGGCCATTCGA
ACGAAGGCATGATCCAGGCGCTGGAAAAACAGGCGCGCAAGCTGCTCAACCCGAGCCCGGCGTTCTACAACGAGCCGATG
CTGAAGCTGGCGCAGCAGCTCACCGATAACAGCTGCTTCGACAAGGTCTTCTTCGCCAACAGCGGCGCGGAAGCCAACGA
AGGCGCGATCAAGCTCGCACGCAAGTGGGGCCGCAAGCACAAGAACGGCGCGTACGAGATCATCACGATGGACCACAGCT
TCCATGGCCGCACGTTGGCGACCATGAGCGCGTCGGGCAAGGCCGGCTGGGACACGATCTTCGCGCCGCAGGTGCCGGGC
TTCCCGAAGGCCGAGCTGAACGACCTGGCTTCGGTGGAAAAGCTGATCACCGACAAGACCGTTGGCATCATGCTCGAGCC
GGTGCAGGGCGAAGGCGGCGTGATTCCCGCCACGCGCGAATTCATGCAGGGCCTGCGCGCGCTGGCCGACAAGCACAAGC
TGCTGTTCATCGTCGATGAAGTGCAGACCGGCTGCGGCCGCTGCGGCACGCTGTTCGCGTATGAGCTGTCGGGTGTGGAG
CCGGACATCATGACGCTCGGCAAGGGCATTGGTGGCGGCGTGCCGCTGTCCGCGCTGCTGTGCAAGGCCGATGTCGCCAG
CTTCGAAGCCGGCGACCAGGGCGGCACGTACAACGGCAATCCGCTGATGACGGCCGTGGGCAGCTCGGTCATGGAACAAC
TGACCGCGCCGGGCTTCCTGGACGACGTGAAGGCCAAGGGCGAGTACCTGCGCGAGCAACTGCTGGTGCTGACGAAGGAA
TTCGGCCTGGGTGGCGAACGTGGTGAAGGCCTGCTGCGCGCGCTGGTGCTGGGCAAGGACATCGGCCCGCAACTGGTGGA
AGAAGCACGCGAAATGTCGCCGGTGGGCCTGCTGCTGAACGCGCCGCGCCCGAACCTGCTGCGCTTCATGCCCGCGCTGA
ACGTGACCCGCGAAGAGATCGACCAGATGATCGGCATGCTGCGCGAGTTGCTGAAGAAGCTGGCCTGA

Upstream 100 bases:

>100_bases
ACCGTCAACAGCGTCTGTTCAGGTCAACAAGCCACGGGCAATCCCCGTGGCTTTTTGCTTTTTTCGACTTTTAGTTTCAT
GCCGACCCCAGGAGTCCGCC

Downstream 100 bases:

>100_bases
CTTCACGCCATGCAATGAAAAATGCCTCGCTTTCGCGAGGCATTTTTTGTTTGAAGCACCGGGTGTCTGCTCCCCTCTCC
CGCAAGCAGGAGACAGGAGC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAFAEFPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNALGHSNEGMIQALEKQARKLLNPSPAFYNEPM
LKLAQQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAYEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPG
FPKAELNDLASVEKLITDKTVGIMLEPVQGEGGVIPATREFMQGLRALADKHKLLFIVDEVQTGCGRCGTLFAYELSGVE
PDIMTLGKGIGGGVPLSALLCKADVASFEAGDQGGTYNGNPLMTAVGSSVMEQLTAPGFLDDVKAKGEYLREQLLVLTKE
FGLGGERGEGLLRALVLGKDIGPQLVEEAREMSPVGLLLNAPRPNLLRFMPALNVTREEIDQMIGMLRELLKKLA

Sequences:

>Translated_395_residues
MAFAEFPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNALGHSNEGMIQALEKQARKLLNPSPAFYNEPM
LKLAQQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAYEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPG
FPKAELNDLASVEKLITDKTVGIMLEPVQGEGGVIPATREFMQGLRALADKHKLLFIVDEVQTGCGRCGTLFAYELSGVE
PDIMTLGKGIGGGVPLSALLCKADVASFEAGDQGGTYNGNPLMTAVGSSVMEQLTAPGFLDDVKAKGEYLREQLLVLTKE
FGLGGERGEGLLRALVLGKDIGPQLVEEAREMSPVGLLLNAPRPNLLRFMPALNVTREEIDQMIGMLRELLKKLA
>Mature_394_residues
AFAEFPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNALGHSNEGMIQALEKQARKLLNPSPAFYNEPML
KLAQQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAYEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGF
PKAELNDLASVEKLITDKTVGIMLEPVQGEGGVIPATREFMQGLRALADKHKLLFIVDEVQTGCGRCGTLFAYELSGVEP
DIMTLGKGIGGGVPLSALLCKADVASFEAGDQGGTYNGNPLMTAVGSSVMEQLTAPGFLDDVKAKGEYLREQLLVLTKEF
GLGGERGEGLLRALVLGKDIGPQLVEEAREMSPVGLLLNAPRPNLLRFMPALNVTREEIDQMIGMLRELLKKLA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=376, Percent_Identity=34.0425531914894, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=34.5637583892617, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI13994255, Length=432, Percent_Identity=27.3148148148148, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=29.97542997543, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=29.7297297297297, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=26.9417475728155, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.7927461139896, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=24.3055555555556, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=24.3055555555556, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=24.3055555555556, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1788044, Length=364, Percent_Identity=44.2307692307692, Blast_Score=300, Evalue=8e-83,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=40.2116402116402, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=31.5521628498728, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=29.6675191815857, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=33.2335329341317, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=29.8507462686567, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786991, Length=327, Percent_Identity=27.82874617737, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=33.5078534031414, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=27.972027972028, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25144274, Length=278, Percent_Identity=34.1726618705036, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=27.972027972028, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=31.4465408805031, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=24.4851258581236, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=388, Percent_Identity=34.7938144329897, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323470, Length=383, Percent_Identity=34.2036553524804, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=23.5981308411215, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=420, Percent_Identity=25.952380952381, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=34.3915343915344, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=26.3285024154589, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=26.9953051643192, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574759, Length=380, Percent_Identity=28.1578947368421, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281366494, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667139, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667143, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42931; Mature: 42800

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFAEFPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNALGHSNEGMIQA
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCHHEECCCCCCCHHHHH
LEKQARKLLNPSPAFYNEPMLKLAQQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKH
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCC
KNGAYEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGFPKAELNDLASVEKLITDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCC
VGIMLEPVQGEGGVIPATREFMQGLRALADKHKLLFIVDEVQTGCGRCGTLFAYELSGVE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLSALLCKADVASFEAGDQGGTYNGNPLMTAVGSSVMEQLTAPGFL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DDVKAKGEYLREQLLVLTKEFGLGGERGEGLLRALVLGKDIGPQLVEEAREMSPVGLLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEE
APRPNLLRFMPALNVTREEIDQMIGMLRELLKKLA
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFAEFPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNALGHSNEGMIQA
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCHHEECCCCCCCHHHHH
LEKQARKLLNPSPAFYNEPMLKLAQQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKH
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCC
KNGAYEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGFPKAELNDLASVEKLITDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCC
VGIMLEPVQGEGGVIPATREFMQGLRALADKHKLLFIVDEVQTGCGRCGTLFAYELSGVE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLSALLCKADVASFEAGDQGGTYNGNPLMTAVGSSVMEQLTAPGFL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DDVKAKGEYLREQLLVLTKEFGLGGERGEGLLRALVLGKDIGPQLVEEAREMSPVGLLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEE
APRPNLLRFMPALNVTREEIDQMIGMLRELLKKLA
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]