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The map label for this gene is ldcC [H]

Identifier: 94311686

GI number: 94311686

Start: 2994254

End: 2996518

Strand: Reverse

Name: ldcC [H]

Synonym: Rmet_2754

Alternate gene names: 94311686

Gene position: 2996518-2994254 (Counterclockwise)

Preceding gene: 94311687

Following gene: 94311681

Centisome position: 76.28

GC content: 63.18

Gene sequence:

>2265_bases
ATGAAATTCCGCTTCCCCGTCATCATCATCGATGAAGACTTCCGCTCCGAGAACATCTCCGGCTCGGGCATTCGCGCGTT
GGCCGAGGCCATCGAGAATGAAGGCATGGAAGTGATGGGTCTGACCAGCTATGGCGACTTGACGTCGTTCGCCCAGCAGT
CCAGCCGGGCATCCACGTTCATCGTGTCGATCGACGACGACGAGTTCGTGCGCGCCGACGATCAGCCCGAAGCGGCCGCC
ATCGAGAAGCTGCGCGCGTTCGTGACCGAAGTGCGTCGCCGCAACACGGATCTGCCGATCTTCCTGTATGGCGAGACGCG
CACGTCGCGCCATATTCCGAACGACATCCTGCGCGAGCTGCACGGCTTCATCCACATGTTCGAGGACACCCCCGAATTCG
TGGCGCGCCACATCATCCGCGAAGCCAAGGTCTACCTGGATTCGCTGGCCCCGCCGTTCTTCAAGGCGCTGATCGACTAC
GCGCAGGACAGCTCGTACTCGTGGCACTGCCCGGGGCACTCGGGCGGCGTGGCGTTCCTGAAGAGCCCGGTGGGCCAGGT
GTTCCACCAGTTCTTCGGCGAGAACATGCTGCGCGCCGACGTCTGCAACGCGGTCGAGGAACTTGGCCAGCTGCTGGACC
ACACCGGCCCGGTGGCGGCGTCGGAGCGCAACGCCGCGCGCATCTTCAATTCCGACCACATGTTCTTCGTGACCAACGGC
ACGTCGACGTCGAACAAGATGGTCTGGCACGCCAACGTGGCGCCGGGCGACATCGTGGTGGTGGACCGTAACTGCCACAA
GTCGATCCTGCACGCGATCATGATGACGGGCGCAATTCCGGTGTTCCTGATGCCGACGCGCAACCACTACGGCATCATCG
GCCCGATTCCGAAGAGCGAGTTCGACCCGGAGACGATCCGCAGGAAGATCGAGAACCATCCGTTCGCGAGCAAGGCGAAG
AACCAGAAGCCGCGCATCCTGACGATCACGCAGGGTACGTACGACGGCGTGCTGTACAACGCCGAGCAGATCAAGGAAAT
GCTGACGTCGGAAATCGACACGCTGCATTTCGACGAGGCATGGCTGCCGCACGCGGCGTTCCACGATTTCTATCGCGACA
TGCACGCGATCGGCCGTGACCGTCCGCGCAGCAAGGACGCGCTGGTGTTCGCCACGCAGTCCACGCACAAGCTGCTGGCC
GGCCTGTCGCAGGCCTCGCAGATCCTCGTGCAGGATTCGGAAACGCGCAAGCTGGATCGCTACCGCTTCAACGAGGCGTA
TCTGATGCACACCTCGACGAGCCCGCAGTACTCGATCATTGCCTCGTGCGACGTGGCCGCGGCGATGATGGAAGCGCCGG
GCGGCACCGCGCTGGTCGAGGAAAGCATCCAGGAAGCGCTGGACTTCCGCCGTGCCGTGCGCAAGGTGGAAGCCGACTAC
GACGTCGCCAACAATGGCGACTGGTGGTTCAAGGTGTGGGGCCCGGACGCGCTGGCCGAAGACGGCATTCCTGACCGCGA
AGAGTGGATGCTCAAGGCCAACGAGCGCTGGCATGGCTTCGGCGATCTGGCCGATGGTTTCAACCTGCTGGATCCGATCA
AGGCCACGATCATCACCCCGGGCCTCGACGTGGACGGCGAGTTCAGCGAGCGCGGCATCCCGGCGGCAATCGTCACGAAG
TACCTGGCCGAGCACGGCATCATCATCGAGAAGACGGGTCTGTACTCGTTCTTCATCATGTTCACGATCGGCATCACCAA
GGGCCGCTGGAACTCGCTGGTGACCGAGCTGCAGCAGTTCAAGGACGACTACGACCAGAACCAGCCGCTGTGGCGCGTGC
TGCCCGAGTTCGTGGGCAAGCACCCGCAGTACGAGCGGCTGGGCCTGCGTGATCTGTGCGACGCGATCCACAGCGTCTAC
AAGGCCAACGATGTGGCGCGCGTGACCACCGAGATGTACCTGTCGGACATGGAGCCGGCGATGAAGCCGTCGGATGCCTG
GGCGATGATGGCGCATCGCGAAATCGAGCGCGTGCCCGTCGACGAACTGGAAGGCCGCGTGACCGCGATCCTGCTGACGC
CGTACCCGCCGGGCATTCCGCTGCTGATCCCGGGCGAGCGCTTCAACCGCACGATCGTGAAGTACCTGAAGTTCGCGCGC
GAGTTCAACAAGCTCTTCCCGGGCTTCGAGACCGACATCCACGGCCTGGTCGAGGACGAGGTCGATGGCCAGAAGGCGTA
CTTCGTGGATTGCGTGAAGCAGTAA

Upstream 100 bases:

>100_bases
GTCAGACCTGACGAAAGAGCCACATGCCGCCGTTTGCGGGGAACTCCCCGCCGGCCATGTGGCTCAAGTTCTTTCCAAGC
ACGCTCATCAAGGATGCCCG

Downstream 100 bases:

>100_bases
GGCTTCACAGCAAGGCTTCATTCGATCCAAACAAAAACCCCCGTGCCGTGAGGCCGGGGGTTTTTTGTGTCTTGCGTGAT
CTGTGGGGAGAGGGAGAGGG

Product: Arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIENEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVRADDQPEAAA
IEKLRAFVTEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIENHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLTSEIDTLHFDEAWLPHAAFHDFYRDMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIQEALDFRRAVRKVEADY
DVANNGDWWFKVWGPDALAEDGIPDREEWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSERGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERLGLRDLCDAIHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWAMMAHREIERVPVDELEGRVTAILLTPYPPGIPLLIPGERFNRTIVKYLKFAR
EFNKLFPGFETDIHGLVEDEVDGQKAYFVDCVKQ

Sequences:

>Translated_754_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIENEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVRADDQPEAAA
IEKLRAFVTEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIENHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLTSEIDTLHFDEAWLPHAAFHDFYRDMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIQEALDFRRAVRKVEADY
DVANNGDWWFKVWGPDALAEDGIPDREEWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSERGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERLGLRDLCDAIHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWAMMAHREIERVPVDELEGRVTAILLTPYPPGIPLLIPGERFNRTIVKYLKFAR
EFNKLFPGFETDIHGLVEDEVDGQKAYFVDCVKQ
>Mature_754_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIENEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVRADDQPEAAA
IEKLRAFVTEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIENHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLTSEIDTLHFDEAWLPHAAFHDFYRDMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIQEALDFRRAVRKVEADY
DVANNGDWWFKVWGPDALAEDGIPDREEWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSERGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERLGLRDLCDAIHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWAMMAHREIERVPVDELEGRVTAILLTPYPPGIPLLIPGERFNRTIVKYLKFAR
EFNKLFPGFETDIHGLVEDEVDGQKAYFVDCVKQ

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=768, Percent_Identity=37.7604166666667, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1786384, Length=721, Percent_Identity=37.8640776699029, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1790573, Length=735, Percent_Identity=36.734693877551, Blast_Score=497, Evalue=1e-141,
Organism=Escherichia coli, GI1786909, Length=679, Percent_Identity=33.5787923416789, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI87082193, Length=728, Percent_Identity=32.8296703296703, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85372; Mature: 85372

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAEAIENEGMEVMGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFVRADDQPEAAAIEKLRAFVTEVRRRNTDLPIFLYGETRTSRHIPNDILREL
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
HGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKALIDYAQDSSYSWHCPGHSGGVAFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
KSPVGQVFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCEEEEECC
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSE
CCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCC
FDPETIRRKIENHPFASKAKNQKPRILTITQGTYDGVLYNAEQIKEMLTSEIDTLHFDEA
CCHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHEECCCC
WLPHAAFHDFYRDMHAIGRDRPRSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDR
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEECCCCHHHHHH
YRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIQEALDFRRAVRKVEADY
EECCCEEEEEECCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVANNGDWWFKVWGPDALAEDGIPDREEWMLKANERWHGFGDLADGFNLLDPIKATIITP
CCCCCCCEEEEEECCCHHHCCCCCCHHHHHEECCCCCCCCCCHHCCCCHHCCHHHHEECC
GLDVDGEFSERGIPAAIVTKYLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQF
CCCCCCCHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KDDYDQNQPLWRVLPEFVGKHPQYERLGLRDLCDAIHSVYKANDVARVTTEMYLSDMEPA
HHHHCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MKPSDAWAMMAHREIERVPVDELEGRVTAILLTPYPPGIPLLIPGERFNRTIVKYLKFAR
CCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHH
EFNKLFPGFETDIHGLVEDEVDGQKAYFVDCVKQ
HHHHHCCCCCCCHHHHHHCCCCCCCEEHHHHHCC
>Mature Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAEAIENEGMEVMGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFVRADDQPEAAAIEKLRAFVTEVRRRNTDLPIFLYGETRTSRHIPNDILREL
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
HGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKALIDYAQDSSYSWHCPGHSGGVAFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
KSPVGQVFHQFFGENMLRADVCNAVEELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCEEEEECC
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSE
CCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCC
FDPETIRRKIENHPFASKAKNQKPRILTITQGTYDGVLYNAEQIKEMLTSEIDTLHFDEA
CCHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHEECCCC
WLPHAAFHDFYRDMHAIGRDRPRSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDR
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEECCCCHHHHHH
YRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIQEALDFRRAVRKVEADY
EECCCEEEEEECCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVANNGDWWFKVWGPDALAEDGIPDREEWMLKANERWHGFGDLADGFNLLDPIKATIITP
CCCCCCCEEEEEECCCHHHCCCCCCHHHHHEECCCCCCCCCCHHCCCCHHCCHHHHEECC
GLDVDGEFSERGIPAAIVTKYLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQF
CCCCCCCHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KDDYDQNQPLWRVLPEFVGKHPQYERLGLRDLCDAIHSVYKANDVARVTTEMYLSDMEPA
HHHHCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MKPSDAWAMMAHREIERVPVDELEGRVTAILLTPYPPGIPLLIPGERFNRTIVKYLKFAR
CCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHH
EFNKLFPGFETDIHGLVEDEVDGQKAYFVDCVKQ
HHHHHCCCCCCCHHHHHHCCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]