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The map label for this gene is apaH [H]

Identifier: 94311668

GI number: 94311668

Start: 2971678

End: 2972559

Strand: Direct

Name: apaH [H]

Synonym: Rmet_2736

Alternate gene names: 94311668

Gene position: 2971678-2972559 (Clockwise)

Preceding gene: 94311654

Following gene: 94311677

Centisome position: 75.65

GC content: 57.71

Gene sequence:

>882_bases
ATGCTAAATGTCTGCAAACCCATGCAATATCCTTTAGCCACAGATCGCGACTTATACGCCACTCCAGTAGCAATTGGCGA
CCTCCAAGGCTGCGCGCCCTCGTTTTTTGAACTACTGGAACAGTTACCGCAAGATGCGCCGCTGCGTTTGGTGGGGGATC
TGGTCAACCGCGGCCCGGCTTCGCTGGAAACCCTTCGCACGATCATTTCCATGGGGGATCGGGTGCGAACCGTCCTGGGT
AATCATGATATCCATCTGCTTGCCGTAGCCGCCGGCGTCCGCAAGTCCGGCAAATCAGACACATTAAATGACATTCTTGG
AGCACCTGATAGTGTCGAATTAATCACATGGCTACGCCATCAACCGCTGGCGATCCGCGAAGATGACTACCTGATTGTTC
ATGCAGGTGTCTTGCCCCAATGGACCGCGGAACAGGTAACCAAGCTCGCGCGGGAGGTCGAGGCCGAATTGCAGGGGCCG
AACTGGAAGGCATTTCTGGCCGGGATATTTGGAAATGCCGCCGATCGCTGGCGCGACAACCTGACCGGCATCGAGCGTCA
CCGCGTCATCATCAATGCGCTCACCCGACTGCGCTACTGCACCGCGGATGGCGTCATGGATCTGAAGACCAAGGAAGGAC
TGGACAATGCGCCGGCAGGTGTCATGCCCTGGTTCGAAGTCCCGGACCGGCGCACGAGCGATGTCACCGTGGTGTGCGGT
CACTGGTCCACGCTTGGCCTGGTGATGCGCCCGAATCTGATCGCGCTCGATACGGGCTGCGTCTGGGGCGGCAAACTAAC
CGCCGTGCAAATGGCAGAGCAACCTGAACTGCGTAAGGTCGTTCAGATCGATTGTCCACAATGTCAAGATCCTCTGGCCT
GA

Upstream 100 bases:

>100_bases
GAAGTGGCGGTATTCTATCTGACCCGCAGGCGGCTCCCGAGGCTCCCGTCCAACTTTTTGTAGCGTGGTGTAACCATCCA
TTCATTTTCCTGGGAAACCC

Downstream 100 bases:

>100_bases
GGAACGCGTCCGGCGGCCAGGGGCATTGGAACAGCGGCTCTTAGAGTTGCATGCCCGGATCGGCGAGTCCGCTGATGGCG
CGCTTGCCGTTTTTTGCCTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLNVCKPMQYPLATDRDLYATPVAIGDLQGCAPSFFELLEQLPQDAPLRLVGDLVNRGPASLETLRTIISMGDRVRTVLG
NHDIHLLAVAAGVRKSGKSDTLNDILGAPDSVELITWLRHQPLAIREDDYLIVHAGVLPQWTAEQVTKLAREVEAELQGP
NWKAFLAGIFGNAADRWRDNLTGIERHRVIINALTRLRYCTADGVMDLKTKEGLDNAPAGVMPWFEVPDRRTSDVTVVCG
HWSTLGLVMRPNLIALDTGCVWGGKLTAVQMAEQPELRKVVQIDCPQCQDPLA

Sequences:

>Translated_293_residues
MLNVCKPMQYPLATDRDLYATPVAIGDLQGCAPSFFELLEQLPQDAPLRLVGDLVNRGPASLETLRTIISMGDRVRTVLG
NHDIHLLAVAAGVRKSGKSDTLNDILGAPDSVELITWLRHQPLAIREDDYLIVHAGVLPQWTAEQVTKLAREVEAELQGP
NWKAFLAGIFGNAADRWRDNLTGIERHRVIINALTRLRYCTADGVMDLKTKEGLDNAPAGVMPWFEVPDRRTSDVTVVCG
HWSTLGLVMRPNLIALDTGCVWGGKLTAVQMAEQPELRKVVQIDCPQCQDPLA
>Mature_293_residues
MLNVCKPMQYPLATDRDLYATPVAIGDLQGCAPSFFELLEQLPQDAPLRLVGDLVNRGPASLETLRTIISMGDRVRTVLG
NHDIHLLAVAAGVRKSGKSDTLNDILGAPDSVELITWLRHQPLAIREDDYLIVHAGVLPQWTAEQVTKLAREVEAELQGP
NWKAFLAGIFGNAADRWRDNLTGIERHRVIINALTRLRYCTADGVMDLKTKEGLDNAPAGVMPWFEVPDRRTSDVTVVCG
HWSTLGLVMRPNLIALDTGCVWGGKLTAVQMAEQPELRKVVQIDCPQCQDPLA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=256, Percent_Identity=42.96875, Blast_Score=212, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 32286; Mature: 32286

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVCKPMQYPLATDRDLYATPVAIGDLQGCAPSFFELLEQLPQDAPLRLVGDLVNRGPA
CCCCCCCCCCCCCCCCCCEECCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCC
SLETLRTIISMGDRVRTVLGNHDIHLLAVAAGVRKSGKSDTLNDILGAPDSVELITWLRH
HHHHHHHHHHCCHHHHHHHCCCCEEEEEEEHHHHCCCCCCCHHHHHCCCCHHHHHHHHHC
QPLAIREDDYLIVHAGVLPQWTAEQVTKLAREVEAELQGPNWKAFLAGIFGNAADRWRDN
CCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
LTGIERHRVIINALTRLRYCTADGVMDLKTKEGLDNAPAGVMPWFEVPDRRTSDVTVVCG
CCCHHHHHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
HWSTLGLVMRPNLIALDTGCVWGGKLTAVQMAEQPELRKVVQIDCPQCQDPLA
CCCCCCEEECCCEEEEECCCEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLNVCKPMQYPLATDRDLYATPVAIGDLQGCAPSFFELLEQLPQDAPLRLVGDLVNRGPA
CCCCCCCCCCCCCCCCCCEECCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCC
SLETLRTIISMGDRVRTVLGNHDIHLLAVAAGVRKSGKSDTLNDILGAPDSVELITWLRH
HHHHHHHHHHCCHHHHHHHCCCCEEEEEEEHHHHCCCCCCCHHHHHCCCCHHHHHHHHHC
QPLAIREDDYLIVHAGVLPQWTAEQVTKLAREVEAELQGPNWKAFLAGIFGNAADRWRDN
CCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
LTGIERHRVIINALTRLRYCTADGVMDLKTKEGLDNAPAGVMPWFEVPDRRTSDVTVVCG
CCCHHHHHHHHHHHHHHHHHCCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
HWSTLGLVMRPNLIALDTGCVWGGKLTAVQMAEQPELRKVVQIDCPQCQDPLA
CCCCCCEEECCCEEEEECCCEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]