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The map label for this gene is cpsG [H]

Identifier: 94311648

GI number: 94311648

Start: 2949236

End: 2950621

Strand: Reverse

Name: cpsG [H]

Synonym: Rmet_2716

Alternate gene names: 94311648

Gene position: 2950621-2949236 (Counterclockwise)

Preceding gene: 335055626

Following gene: 94311647

Centisome position: 75.12

GC content: 64.94

Gene sequence:

>1386_bases
ATGCAAATTGAACCTTCGATCTTCAAGGCCTACGACATCCGTGGCATCGTCGGCAAGACGCTGACCCCCGAAGTGGCCCG
CCTCATCGGCCTCTCTTTTGGCTCCGCCGCCGCCGAGCAGGGCGAGCGGGCGGTGGTGGTCGGCCGTGACGGCCGCCTGT
CCGGGCCCGATCTGCTGGGAGGGCTCGTCGAAGGCCTTCGCGCCGCCGGGCTCGACGTGATCGATCTGGGCATGGTTGCC
ACACCGATGGTCTACTTCGGCACCAATATCGAGCTGGACGGCCGCCGCGCCACGTCCGGCATCATGGTCACGGGCAGCCA
CAACCCGCCCGACTACAACGGTTTCAAGATGGTGCTCGGCGGCAAGGCGATCTACGGTGAGCAGATCCAGGCGCTGCGCC
AACGCATCGAGGCGGGCAACTTCGCCAAGGGTAACGGCGGCTACAAGCTCGTCGATGTGCGCCAGCAATACCTGGATCGC
ATCGTCGGCGATGTGAAGCTGGCGCGCCCCATGAAGATCGCGCTCGATGCCGGCAACGGCGTGGCCGGCGCGTTCGTGGG
CGACCTGTTCCGCGCGCTCGGTTGCGAAGTGACCGAACTGTTCTGCGATGTCGACGGCCATTTCCCGAACCACCATCCCG
ATCCCGCCCACGTGGAGAACCTGCAGGACCTGATCCAGTGCCTGCGCGATACGGATTGCGAGCTGGGTCTGGCATTCGAT
GGTGACGGCGACCGCCTGGGGGTGGTCACCAAGGACGGGCAGGTCATCTTCCCGGACCGGCAACTGATGCTATTCGCGGA
GGAGATCCTCTCGCGCAATCCCGGCGCGCAGGTGATCTACGACGTCAAATGCACGGGCAAGCTGGCACCGTGGATCCGCC
AGCACGGCGGCGAACCGCTGATGTGGAAGACGGGCCATTCGCTGGTCAAGGCCAAACTCAAGGAAACGGGCGCGCCGATC
GCCGGCGAGATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGATGGCCTGTACACGGGCGCGCGGCT
GCTCGAGATCCTGTCGCGCCACGCCGACGCCAGCGCCGTGCTCAACGCACTGCCGAACTCGAATTGCACACCCGAGCTGC
AGCTCAAGTGCGCCGAGGGCGAGGCGTTCACGCTGCTCGACAAGATCCGCGCCAATGCGAAGTTCGACGGCGCGAAGGAA
GTCATCACGATCGACGGCGTTCGCGTCGAGTATCCGGACGGCTTTGGCCTGGCGCGTCCGTCCAACACCACGCCGGTGGT
GGTGATGCGTTTCGAGGCCGACAACGATGCCGCGCTGGCCCGTATCCAGGCCGAATTCAAGCGTGTGATTCTGGCTGAGA
AACCGGATGCGAAGCTCCCGTTCTGA

Upstream 100 bases:

>100_bases
AATCCGGCACAATACGAGTTTTTGGCGCCCTGCCCGCGCCCCGTCCGGCTAGCTGTTGCCGGTCGGTATCGCACCGTGAA
CTTCAGACATGGGAAGCCAT

Downstream 100 bases:

>100_bases
CGTCGTGCAGGTATCGAACCAGGAGACACCGTCGCCGCAAGCGGCGGTGTCTCCGTTTGGGCTGCCCGCGCGGCCTCGTA
TCCTGATCGTCAAGGTGTCG

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQIEPSIFKAYDIRGIVGKTLTPEVARLIGLSFGSAAAEQGERAVVVGRDGRLSGPDLLGGLVEGLRAAGLDVIDLGMVA
TPMVYFGTNIELDGRRATSGIMVTGSHNPPDYNGFKMVLGGKAIYGEQIQALRQRIEAGNFAKGNGGYKLVDVRQQYLDR
IVGDVKLARPMKIALDAGNGVAGAFVGDLFRALGCEVTELFCDVDGHFPNHHPDPAHVENLQDLIQCLRDTDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILSRNPGAQVIYDVKCTGKLAPWIRQHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHADASAVLNALPNSNCTPELQLKCAEGEAFTLLDKIRANAKFDGAKE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF

Sequences:

>Translated_461_residues
MQIEPSIFKAYDIRGIVGKTLTPEVARLIGLSFGSAAAEQGERAVVVGRDGRLSGPDLLGGLVEGLRAAGLDVIDLGMVA
TPMVYFGTNIELDGRRATSGIMVTGSHNPPDYNGFKMVLGGKAIYGEQIQALRQRIEAGNFAKGNGGYKLVDVRQQYLDR
IVGDVKLARPMKIALDAGNGVAGAFVGDLFRALGCEVTELFCDVDGHFPNHHPDPAHVENLQDLIQCLRDTDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILSRNPGAQVIYDVKCTGKLAPWIRQHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHADASAVLNALPNSNCTPELQLKCAEGEAFTLLDKIRANAKFDGAKE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
>Mature_461_residues
MQIEPSIFKAYDIRGIVGKTLTPEVARLIGLSFGSAAAEQGERAVVVGRDGRLSGPDLLGGLVEGLRAAGLDVIDLGMVA
TPMVYFGTNIELDGRRATSGIMVTGSHNPPDYNGFKMVLGGKAIYGEQIQALRQRIEAGNFAKGNGGYKLVDVRQQYLDR
IVGDVKLARPMKIALDAGNGVAGAFVGDLFRALGCEVTELFCDVDGHFPNHHPDPAHVENLQDLIQCLRDTDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILSRNPGAQVIYDVKCTGKLAPWIRQHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHADASAVLNALPNSNCTPELQLKCAEGEAFTLLDKIRANAKFDGAKE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=465, Percent_Identity=32.6881720430108, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1789566, Length=443, Percent_Identity=27.765237020316, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49907; Mature: 49907

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIEPSIFKAYDIRGIVGKTLTPEVARLIGLSFGSAAAEQGERAVVVGRDGRLSGPDLLG
CCCCCCHHHHEECCHHCCCCCCHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCCHHHHH
GLVEGLRAAGLDVIDLGMVATPMVYFGTNIELDGRRATSGIMVTGSHNPPDYNGFKMVLG
HHHHHHHHCCCCEEEHHHHHCCCEEECCCEEECCCCCCCCEEEECCCCCCCCCCEEEEEC
GKAIYGEQIQALRQRIEAGNFAKGNGGYKLVDVRQQYLDRIVGDVKLARPMKIALDAGNG
CCCHHHHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
VAGAFVGDLFRALGCEVTELFCDVDGHFPNHHPDPAHVENLQDLIQCLRDTDCELGLAFD
CHHHHHHHHHHHHCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEC
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILSRNPGAQVIYDVKCTGKLAPWIRQHGGEPL
CCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCCCCCE
MWKTGHSLVKAKLKETGAPIAGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHADASAV
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHH
LNALPNSNCTPELQLKCAEGEAFTLLDKIRANAKFDGAKEVITIDGVRVEYPDGFGLARP
HHHCCCCCCCCCEEEEECCCCEEHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
SNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
CCCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure
MQIEPSIFKAYDIRGIVGKTLTPEVARLIGLSFGSAAAEQGERAVVVGRDGRLSGPDLLG
CCCCCCHHHHEECCHHCCCCCCHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCCHHHHH
GLVEGLRAAGLDVIDLGMVATPMVYFGTNIELDGRRATSGIMVTGSHNPPDYNGFKMVLG
HHHHHHHHCCCCEEEHHHHHCCCEEECCCEEECCCCCCCCEEEECCCCCCCCCCEEEEEC
GKAIYGEQIQALRQRIEAGNFAKGNGGYKLVDVRQQYLDRIVGDVKLARPMKIALDAGNG
CCCHHHHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
VAGAFVGDLFRALGCEVTELFCDVDGHFPNHHPDPAHVENLQDLIQCLRDTDCELGLAFD
CHHHHHHHHHHHHCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEC
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILSRNPGAQVIYDVKCTGKLAPWIRQHGGEPL
CCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCCCCCE
MWKTGHSLVKAKLKETGAPIAGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHADASAV
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHH
LNALPNSNCTPELQLKCAEGEAFTLLDKIRANAKFDGAKEVITIDGVRVEYPDGFGLARP
HHHCCCCCCCCCEEEEECCCCEEHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
SNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
CCCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]