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The map label for this gene is ribBA [H]

Identifier: 94311625

GI number: 94311625

Start: 2924379

End: 2925494

Strand: Direct

Name: ribBA [H]

Synonym: Rmet_2693

Alternate gene names: 94311625

Gene position: 2924379-2925494 (Clockwise)

Preceding gene: 94311621

Following gene: 94311626

Centisome position: 74.45

GC content: 65.77

Gene sequence:

>1116_bases
ATGACTATCTCTCGTATCGAAGACATCATTGCCGACATTCGTGCCGGCCGCATGGTCATCCTTGTGGACGAGGAAGATCG
TGAAAACGAGGGCGACCTTGTCCTGGCGGCCGATTTCGTGACGCCGGAAGCGATCAACTTCATGGCCAAGTACGGCCGCG
GCCTGATCTGCCTGACGCTGACCGCCGAACGCTGCCGCCAGCTTGAGCTGTATCCGATGGTGTCACGCAACGGCACTGTG
CATGGCACCAACTTCACGGTATCCATCGAAGCCGCCGAAGGCGTGACCACCGGCATCTCGGCAGCCGACCGTTCCCGCAC
TGTCCAGGCCGCCGTGGCCCGTGACGCCCGCGCGAGCGACCTGGTGCAGCCCGGTCACATCTTCCCGCTGACAGCCCAGC
CTGGCGGCGTGCTGATCCGCGCCGGCCATACCGAGGCTGGCTGCGACCTTGGCACCCTGGCTGGCCTGACGCCCGCCGCG
GTGATCTGCGAAATCATGAAGGACGACGGTACGATGGCCCGGCTGCCGGACCTGATCGAGTTCGCGCGCGAGCACGACCT
CAAGATCGGAACGATCGCCGACCTGATCCACTACCGCAGCCGCACCGAAAGCATCATCGAACGGGTGGGCGAGCGCGACA
TGCAAACGCCGTGGGGCACGTTCCACAGCGTGCTGTATCGCGACAAGCCGTCCGGCCGCGCCCATGTGGCGTTGGTCAAG
GGCAAGCCCCAGCCGGACCGCGAGACACTGGTGCGTGTGCACGAGCCGTTGTCGGTGCTCGACCTGCTGGAAGCCGGCCA
CACCACCCATTCGTGGAGCCTGCCCGCCGCGCTCGAAGTGCTGCATGGCGCCGAACATGGCGTGATGGTGCTGCTGAACT
GCGGCGACTCGCCGGAAATGCTGTTCGAGCAGTTCGCCGCGCTGGATGCTCCGGAGAACCGTCCGCGCCGCAAGCCGGAC
CTGCGCACCTACGGCGTGGGCGCGCAGATCCTGCGCGACATCGGCGTGGGCAAGATGCGCGTGCTGGGTTCGCCGCAGAA
GATGCCGAGCATGACCGGTTACGAACTCGAGATCGTTGGCTGCCAGCCGATGAGCGGCGAGTCGAATCGCGGCTGA

Upstream 100 bases:

>100_bases
CGTACAATAGCGGCCTTGATTTCGCCGGCATCGTCGCATCCCGCCGCCGGCCCTGCCCGCCAAAAAGCATCCCGCTCGCC
ATTCATACGTCGCCCCAATC

Downstream 100 bases:

>100_bases
CCGGGAACGGATCGTACCGATTGACCCGGCAGCGGCGCATCCGCGCGGCTGCCTGACCGAATCACTGGAGAAATAACAAT
GGATCACGGCTTCTACGAGA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTISRIEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPEAINFMAKYGRGLICLTLTAERCRQLELYPMVSRNGTV
HGTNFTVSIEAAEGVTTGISAADRSRTVQAAVARDARASDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGTLAGLTPAA
VICEIMKDDGTMARLPDLIEFAREHDLKIGTIADLIHYRSRTESIIERVGERDMQTPWGTFHSVLYRDKPSGRAHVALVK
GKPQPDRETLVRVHEPLSVLDLLEAGHTTHSWSLPAALEVLHGAEHGVMVLLNCGDSPEMLFEQFAALDAPENRPRRKPD
LRTYGVGAQILRDIGVGKMRVLGSPQKMPSMTGYELEIVGCQPMSGESNRG

Sequences:

>Translated_371_residues
MTISRIEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPEAINFMAKYGRGLICLTLTAERCRQLELYPMVSRNGTV
HGTNFTVSIEAAEGVTTGISAADRSRTVQAAVARDARASDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGTLAGLTPAA
VICEIMKDDGTMARLPDLIEFAREHDLKIGTIADLIHYRSRTESIIERVGERDMQTPWGTFHSVLYRDKPSGRAHVALVK
GKPQPDRETLVRVHEPLSVLDLLEAGHTTHSWSLPAALEVLHGAEHGVMVLLNCGDSPEMLFEQFAALDAPENRPRRKPD
LRTYGVGAQILRDIGVGKMRVLGSPQKMPSMTGYELEIVGCQPMSGESNRG
>Mature_370_residues
TISRIEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPEAINFMAKYGRGLICLTLTAERCRQLELYPMVSRNGTVH
GTNFTVSIEAAEGVTTGISAADRSRTVQAAVARDARASDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGTLAGLTPAAV
ICEIMKDDGTMARLPDLIEFAREHDLKIGTIADLIHYRSRTESIIERVGERDMQTPWGTFHSVLYRDKPSGRAHVALVKG
KPQPDRETLVRVHEPLSVLDLLEAGHTTHSWSLPAALEVLHGAEHGVMVLLNCGDSPEMLFEQFAALDAPENRPRRKPDL
RTYGVGAQILRDIGVGKMRVLGSPQKMPSMTGYELEIVGCQPMSGESNRG

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=54.228855721393, Blast_Score=225, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6320695, Length=205, Percent_Identity=40, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40416; Mature: 40285

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISRIEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPEAINFMAKYGRGLICLTL
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TAERCRQLELYPMVSRNGTVHGTNFTVSIEAAEGVTTGISAADRSRTVQAAVARDARASD
EHHHCCCEEEEEEECCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
LVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGTLAGLTPAAVICEIMKDDGTMARLPDLIE
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
FAREHDLKIGTIADLIHYRSRTESIIERVGERDMQTPWGTFHSVLYRDKPSGRAHVALVK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEE
GKPQPDRETLVRVHEPLSVLDLLEAGHTTHSWSLPAALEVLHGAEHGVMVLLNCGDSPEM
CCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LFEQFAALDAPENRPRRKPDLRTYGVGAQILRDIGVGKMRVLGSPQKMPSMTGYELEIVG
HHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCEEECCCCHHCCCCCCCEEEEEE
CQPMSGESNRG
CCCCCCCCCCC
>Mature Secondary Structure 
TISRIEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPEAINFMAKYGRGLICLTL
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TAERCRQLELYPMVSRNGTVHGTNFTVSIEAAEGVTTGISAADRSRTVQAAVARDARASD
EHHHCCCEEEEEEECCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
LVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGTLAGLTPAAVICEIMKDDGTMARLPDLIE
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
FAREHDLKIGTIADLIHYRSRTESIIERVGERDMQTPWGTFHSVLYRDKPSGRAHVALVK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEE
GKPQPDRETLVRVHEPLSVLDLLEAGHTTHSWSLPAALEVLHGAEHGVMVLLNCGDSPEM
CCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LFEQFAALDAPENRPRRKPDLRTYGVGAQILRDIGVGKMRVLGSPQKMPSMTGYELEIVG
HHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCEEECCCCHHCCCCCCCEEEEEE
CQPMSGESNRG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]