Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 94311588

GI number: 94311588

Start: 2890173

End: 2890811

Strand: Reverse

Name: ahpC [C]

Synonym: Rmet_2654

Alternate gene names: 94311588

Gene position: 2890811-2890173 (Counterclockwise)

Preceding gene: 335055619

Following gene: 94311586

Centisome position: 73.59

GC content: 60.09

Gene sequence:

>639_bases
ATGGCACTGCGTCTTGGCGATATCGCACCGGATTTTGAACAGGAATCGAGCGAAGGCCGCATCCGCTTCCATGATTGGCT
CGGCGATGGCTGGGGTGTCCTGTTTTCGCATCCGGCGGACTACACCCCGGTGTGCACGACCGAACTGGGCCTGACCGCCC
GGCTGAAAGAAGAGTTCGCAAAGCGCAACGTCAAGGCGATCGCCCTGTCGGTGGATAGTGTGGAATCGCATCACGGCTGG
ATCCAGGACATCAACGACACCCAGTCGACCACGGTCAACTTCCCGATCCTGGCCGACGGTGACCGCAAGGTGTCCGAGCT
ATACGACATGATTCACCCGAACGCCAACGAAACCCTGACGGTGCGTTCGCTGTTCGTGATCGACCCGAAGAAGAAGGTCC
GCCTGATCATTACATACCCTGCCAGCACCGGCCGCAACTTCAACGAGATCCTGCGCGTCATCGATTCGCTGCAGCTCACC
GACAATCACAGCGTGGCCACGCCGGGCAACTGGCAGGACGGCGACGACGTGGTGATCGTGCCCTCGCTGAAGGACGAAGA
GGTCATCCGCCAGAAATTCCCGAAGGGTTACAAGGCCGTACGTCCGTACCTGCGTCTGACGCCGCAGCCCAACAAGTGA

Upstream 100 bases:

>100_bases
TTATATTCGTTTGGGTTGGAAGGCAATCCAACTAAGCTCGGTTCCCTGTGTTTGCACGTCATTCCTTACGTTTATTTACT
GTTGTTTCAGGAGACCCCCG

Downstream 100 bases:

>100_bases
AAAAACCGGGCCCGGGGTTTGCCCCCGGGCCCGGTTCAGTGCCACTGACCTTTCTAATGATGTCGTAAAACGGCGGGCTT
GCCCGTCGTCTCCTTGGTAG

Product: antioxidant protein LsfA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MALRLGDIAPDFEQESSEGRIRFHDWLGDGWGVLFSHPADYTPVCTTELGLTARLKEEFAKRNVKAIALSVDSVESHHGW
IQDINDTQSTTVNFPILADGDRKVSELYDMIHPNANETLTVRSLFVIDPKKKVRLIITYPASTGRNFNEILRVIDSLQLT
DNHSVATPGNWQDGDDVVIVPSLKDEEVIRQKFPKGYKAVRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MALRLGDIAPDFEQESSEGRIRFHDWLGDGWGVLFSHPADYTPVCTTELGLTARLKEEFAKRNVKAIALSVDSVESHHGW
IQDINDTQSTTVNFPILADGDRKVSELYDMIHPNANETLTVRSLFVIDPKKKVRLIITYPASTGRNFNEILRVIDSLQLT
DNHSVATPGNWQDGDDVVIVPSLKDEEVIRQKFPKGYKAVRPYLRLTPQPNK
>Mature_211_residues
ALRLGDIAPDFEQESSEGRIRFHDWLGDGWGVLFSHPADYTPVCTTELGLTARLKEEFAKRNVKAIALSVDSVESHHGWI
QDINDTQSTTVNFPILADGDRKVSELYDMIHPNANETLTVRSLFVIDPKKKVRLIITYPASTGRNFNEILRVIDSLQLTD
NHSVATPGNWQDGDDVVIVPSLKDEEVIRQKFPKGYKAVRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=52.2522522522522, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=32.8042328042328, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI4505591, Length=181, Percent_Identity=31.4917127071823, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI32455266, Length=181, Percent_Identity=31.4917127071823, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI32455264, Length=181, Percent_Identity=31.4917127071823, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=33.1081081081081, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=31.055900621118, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=31.055900621118, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=42.2110552763819, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=188, Percent_Identity=32.9787234042553, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32565831, Length=188, Percent_Identity=32.9787234042553, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=31.25, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=54.2452830188679, Blast_Score=231, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=32.0512820512821, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=156, Percent_Identity=30.1282051282051, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=51.5981735159817, Blast_Score=226, Evalue=8e-60,
Organism=Drosophila melanogaster, GI24652434, Length=209, Percent_Identity=48.3253588516746, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24652436, Length=209, Percent_Identity=48.3253588516746, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17975518, Length=209, Percent_Identity=48.3253588516746, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17157991, Length=168, Percent_Identity=31.547619047619, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24641739, Length=168, Percent_Identity=31.547619047619, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=30.1136363636364, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=30.1136363636364, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23939; Mature: 23808

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRLGDIAPDFEQESSEGRIRFHDWLGDGWGVLFSHPADYTPVCTTELGLTARLKEEFA
CEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCEEECCCCCHHHHHHHHH
KRNVKAIALSVDSVESHHGWIQDINDTQSTTVNFPILADGDRKVSELYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPKKKVRLIITYPASTGRNFNEILRVIDSLQLTDNHSVATPGNWQDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEE
PSLKDEEVIRQKFPKGYKAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
ALRLGDIAPDFEQESSEGRIRFHDWLGDGWGVLFSHPADYTPVCTTELGLTARLKEEFA
EEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCEEECCCCCHHHHHHHHH
KRNVKAIALSVDSVESHHGWIQDINDTQSTTVNFPILADGDRKVSELYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPKKKVRLIITYPASTGRNFNEILRVIDSLQLTDNHSVATPGNWQDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEE
PSLKDEEVIRQKFPKGYKAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]