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The map label for this gene is zupT [H]

Identifier: 94311557

GI number: 94311557

Start: 2852063

End: 2852938

Strand: Reverse

Name: zupT [H]

Synonym: Rmet_2621

Alternate gene names: 94311557

Gene position: 2852938-2852063 (Counterclockwise)

Preceding gene: 94311558

Following gene: 94311553

Centisome position: 72.63

GC content: 64.04

Gene sequence:

>876_bases
GTGGCGCCTGCCCGACTCCGGGCGGACACCGGTTCCGGGGAGCCCATCATCCATTCCACGCTTCTGTACATCCTGCTGGC
CGCGACGATCTCGGGCGTCGGCAGCATTTTTGGCGCGGCGCTGCTCTCGCTGACCGTCGCGTCGCGCGTGGTGGAGCGCA
TGGTGAGCTTTTCAGTCGGGGTGCTGCTGGCCACCGCGCTGCTGCATTCGCTGCCCGAGGCCTTCGAATCCGGTGCTGAT
ACGCGTGCGCTGTTCGGCACATTGCTGGCGGGACTTCTCGGCTTCTTCCTGCTGGAGAAGATCTCGCTGCTGCGTCATTC
GCATCACCACGAGGGCGACGGGCATCATCACCATCACGGGCATGACCGCGAGGAAGCGGGGCGCAGCGGCCTGACGATCC
TGGTGGGCGATACCTTCCACAACTTTGCCGACGGCATCGTGATTGCTGCCGCATTCCTTGCCAATCCGCATATCGGCATC
GTCACTGCGCTGGCGATCGCCGCACACGAAATCCCGCAGGAAGTGGGCGACTTCATCGTGCTGCTGAATGCCGGGTTCTC
GAAGGCGCGCGCGTTTGCGTTCAACCTGCTGTCGAGCCTGGCGGCCATCATCGGCGGGCTGGTCGGATATTTTCTGCTCG
ACCAGCTCACGGGCTGGATTCCGTACGTGCTGGTGATCGCGTCGAGCAGCTTCCTCTACATTGCCGTGAGCGATCTGATG
CCGCAGATGCAGCGCAAGCCGCGACTCAAGGAGTCGGCGGTGCAGGTGGTGTTGGTGGCGGCCGGCATTGCGGCCATCGT
TTTCATCACGAATGGCGTGCACGAGCAACACGGGCATCGCCACTCGCGCACCGCCGCCGGGGTGACATCGAACTGA

Upstream 100 bases:

>100_bases
ATGTCCATCTGGCCCTTCCGGCGTTACGGTCATTGCAAAGACTGTGCGGACGTACGTACAATGCCGCTTTCACGTTTTTG
CAACATTGTTGCGTTAATCG

Downstream 100 bases:

>100_bases
TGTCGCTGGCGGGAATTCCGGCTTAGCTGCCGGTGGCGACTGGCCGCTTCGGGTCAGCGCACCACTCGCTCCATGAGCCC
GGATAGAGCGCCGCGCCGGT

Product: putative divalent heavy-metal cations transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAPARLRADTGSGEPIIHSTLLYILLAATISGVGSIFGAALLSLTVASRVVERMVSFSVGVLLATALLHSLPEAFESGAD
TRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIVIAAAFLANPHIGI
VTALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSLAAIIGGLVGYFLLDQLTGWIPYVLVIASSSFLYIAVSDLM
PQMQRKPRLKESAVQVVLVAAGIAAIVFITNGVHEQHGHRHSRTAAGVTSN

Sequences:

>Translated_291_residues
MAPARLRADTGSGEPIIHSTLLYILLAATISGVGSIFGAALLSLTVASRVVERMVSFSVGVLLATALLHSLPEAFESGAD
TRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIVIAAAFLANPHIGI
VTALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSLAAIIGGLVGYFLLDQLTGWIPYVLVIASSSFLYIAVSDLM
PQMQRKPRLKESAVQVVLVAAGIAAIVFITNGVHEQHGHRHSRTAAGVTSN
>Mature_290_residues
APARLRADTGSGEPIIHSTLLYILLAATISGVGSIFGAALLSLTVASRVVERMVSFSVGVLLATALLHSLPEAFESGADT
RALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIVIAAAFLANPHIGIV
TALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSLAAIIGGLVGYFLLDQLTGWIPYVLVIASSSFLYIAVSDLMP
QMQRKPRLKESAVQVVLVAAGIAAIVFITNGVHEQHGHRHSRTAAGVTSN

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI223633937, Length=252, Percent_Identity=32.5396825396825, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI223633939, Length=289, Percent_Identity=30.4498269896194, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI40255101, Length=307, Percent_Identity=27.6872964169381, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI190014617, Length=314, Percent_Identity=27.7070063694268, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI187936949, Length=128, Percent_Identity=39.84375, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI55741750, Length=128, Percent_Identity=39.84375, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI153252201, Length=131, Percent_Identity=35.1145038167939, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI205830424, Length=127, Percent_Identity=34.6456692913386, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI190360568, Length=127, Percent_Identity=34.6456692913386, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI190358541, Length=127, Percent_Identity=34.6456692913386, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI205830407, Length=160, Percent_Identity=32.5, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24586665, Length=161, Percent_Identity=32.2981366459627, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI205830403, Length=161, Percent_Identity=32.2981366459627, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI205830405, Length=131, Percent_Identity=35.1145038167939, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI153252214, Length=128, Percent_Identity=34.375, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI205830426, Length=116, Percent_Identity=36.2068965517241, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI115430255, Length=123, Percent_Identity=39.8373983739837, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI117553619, Length=128, Percent_Identity=34.375, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI117553608, Length=128, Percent_Identity=34.375, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI115430259, Length=123, Percent_Identity=39.8373983739837, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI206597541, Length=146, Percent_Identity=33.5616438356164, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI206597539, Length=146, Percent_Identity=33.5616438356164, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789419, Length=197, Percent_Identity=26.9035532994924, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193209531, Length=273, Percent_Identity=28.2051282051282, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994730, Length=277, Percent_Identity=24.5487364620939, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992548, Length=134, Percent_Identity=30.5970149253731, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71998183, Length=155, Percent_Identity=32.258064516129, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538884, Length=110, Percent_Identity=38.1818181818182, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32566720, Length=145, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32566718, Length=145, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322166, Length=248, Percent_Identity=26.2096774193548, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI161083817, Length=114, Percent_Identity=42.9824561403509, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24664383, Length=114, Percent_Identity=42.9824561403509, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24651189, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24651193, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24651187, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24651191, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24651195, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24651197, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45549201, Length=138, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864610, Length=148, Percent_Identity=33.7837837837838, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 30785; Mature: 30654

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPARLRADTGSGEPIIHSTLLYILLAATISGVGSIFGAALLSLTVASRVVERMVSFSVG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLATALLHSLPEAFESGADTRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HDREEAGRSGLTILVGDTFHNFADGIVIAAAFLANPHIGIVTALAIAAHEIPQEVGDFIV
CCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEE
LLNAGFSKARAFAFNLLSSLAAIIGGLVGYFLLDQLTGWIPYVLVIASSSFLYIAVSDLM
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHH
PQMQRKPRLKESAVQVVLVAAGIAAIVFITNGVHEQHGHRHSRTAAGVTSN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
APARLRADTGSGEPIIHSTLLYILLAATISGVGSIFGAALLSLTVASRVVERMVSFSVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLATALLHSLPEAFESGADTRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HDREEAGRSGLTILVGDTFHNFADGIVIAAAFLANPHIGIVTALAIAAHEIPQEVGDFIV
CCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEE
LLNAGFSKARAFAFNLLSSLAAIIGGLVGYFLLDQLTGWIPYVLVIASSSFLYIAVSDLM
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHH
PQMQRKPRLKESAVQVVLVAAGIAAIVFITNGVHEQHGHRHSRTAAGVTSN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA