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The map label for this gene is mcr [H]

Identifier: 94311533

GI number: 94311533

Start: 2823630

End: 2824733

Strand: Reverse

Name: mcr [H]

Synonym: Rmet_2597

Alternate gene names: 94311533

Gene position: 2824733-2823630 (Counterclockwise)

Preceding gene: 94311534

Following gene: 94311530

Centisome position: 71.91

GC content: 67.75

Gene sequence:

>1104_bases
ATGAGCACGTCCGGTGCCACCCTTGCGGCCCCCGCGGCCCCTGCGGCGAATGCAGCCGCAGCGCCGCCACTCGCGGGCGT
GCGCGTCGTCGACCTGACCGAACTGCTCCCCGGCCCGTTCCTGACGCAGACGCTCCTCGAGATGGGTGCCGAGGTGGTGA
AGATCGAGCGCCCACCGCACGGCGACAATGCCCGGCGTCTGGCGCCGGGGCTGTTCGCAGCGCTCAACCGTGGCAAACAC
AGCCTGTATTGCGACTTGAAGAGCGACAGCGGACTGGCCGAGGTGCGGGCGCAGATCGCGCAGGCGGACATCCTGATCGA
GTCCTATCGCCCGGGCGCGATGCGTCGGCTCGGGCTGGACTACGAGAGCCTCCGCGAGCAGTTTCCCCGGCTGATCTACC
TGTCGCTGACCGGGTTTGGACAGGACGGTCCCCATGCGCTGCTGCCAGGGCACGACATCAACTATCTTGCTGCGGCGGGC
GCGCTGTCGCTGACGGGCACGCCCGGTGGTCCTCCGGTGCACCAAGCCATGCTGCCGATCGCGGATCTGGCCGGGGCCTC
CATGGCGCTATCCGCGCTGCTGGCCGCGCTCTACCAGCGCACAGGGAGTGGACGAGGCCAGTATCTGGATGCGGCGCTCG
CCGATAGCGTTCTGCACTGGATGGCGCCAAGGCTGGGGCTGTTCCGCCAGAAGGCCGCAACTACGGCTGACGCACAGCGA
GCGATGCTGGGCGGTAAGCCAGCCTATGGCGTGTTCCGTTGCAGGGATGGTCGCTATCTGACCATCGCCGCGCTGGAAGA
GCATTTCTGGCGAGGTCTGAATGACGTGCTGGGTCTGTTTGCCGCCAATGATGCGTGTTGCGTGGACCACGCCGCGAGGA
CCGCGAATGCGGAGACGATCAATGCGCGCCTAGCCGAGCGCGTGGCGGAGTATGACGCCGATACGCTGATGGCGCGGCTG
GCGAATGCGGACCTGCCGGTGTTCCCGGTGCTGGATGCGGTGGAGGCTGTCGCGCAAGCCCGTCACAGATCGGGTGCGCG
GATCACGGAGACGGAAGACGGGCCGCTGCCCGGATTCCCCGTGACGCTGGAAGGCATGGCCTGA

Upstream 100 bases:

>100_bases
TGGTCGAGATGGATCTGAATCCGGTATGGGTCGGCGTTGCGGGAGAGGGCGCATTGCCGCTCGATGCGGTGATCGTGATG
GAGCAAGGGGAGGGTGGAAA

Downstream 100 bases:

>100_bases
ACATGGCCTGACGTCACGTGGGGCGCAGGCCTTGCCCGCGCCCCACGATGATGTCCTTGCTGATGCCCCGATGGTCAGTC
CAGCTTGGCGCCGGACTTCT

Product: alpha-methylacyl-CoA racemase MCR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSTSGATLAAPAAPAANAAAAPPLAGVRVVDLTELLPGPFLTQTLLEMGAEVVKIERPPHGDNARRLAPGLFAALNRGKH
SLYCDLKSDSGLAEVRAQIAQADILIESYRPGAMRRLGLDYESLREQFPRLIYLSLTGFGQDGPHALLPGHDINYLAAAG
ALSLTGTPGGPPVHQAMLPIADLAGASMALSALLAALYQRTGSGRGQYLDAALADSVLHWMAPRLGLFRQKAATTADAQR
AMLGGKPAYGVFRCRDGRYLTIAALEEHFWRGLNDVLGLFAANDACCVDHAARTANAETINARLAERVAEYDADTLMARL
ANADLPVFPVLDAVEAVAQARHRSGARITETEDGPLPGFPVTLEGMA

Sequences:

>Translated_367_residues
MSTSGATLAAPAAPAANAAAAPPLAGVRVVDLTELLPGPFLTQTLLEMGAEVVKIERPPHGDNARRLAPGLFAALNRGKH
SLYCDLKSDSGLAEVRAQIAQADILIESYRPGAMRRLGLDYESLREQFPRLIYLSLTGFGQDGPHALLPGHDINYLAAAG
ALSLTGTPGGPPVHQAMLPIADLAGASMALSALLAALYQRTGSGRGQYLDAALADSVLHWMAPRLGLFRQKAATTADAQR
AMLGGKPAYGVFRCRDGRYLTIAALEEHFWRGLNDVLGLFAANDACCVDHAARTANAETINARLAERVAEYDADTLMARL
ANADLPVFPVLDAVEAVAQARHRSGARITETEDGPLPGFPVTLEGMA
>Mature_366_residues
STSGATLAAPAAPAANAAAAPPLAGVRVVDLTELLPGPFLTQTLLEMGAEVVKIERPPHGDNARRLAPGLFAALNRGKHS
LYCDLKSDSGLAEVRAQIAQADILIESYRPGAMRRLGLDYESLREQFPRLIYLSLTGFGQDGPHALLPGHDINYLAAAGA
LSLTGTPGGPPVHQAMLPIADLAGASMALSALLAALYQRTGSGRGQYLDAALADSVLHWMAPRLGLFRQKAATTADAQRA
MLGGKPAYGVFRCRDGRYLTIAALEEHFWRGLNDVLGLFAANDACCVDHAARTANAETINARLAERVAEYDADTLMARLA
NADLPVFPVLDAVEAVAQARHRSGARITETEDGPLPGFPVTLEGMA

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI266456254, Length=341, Percent_Identity=33.7243401759531, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI42794625, Length=341, Percent_Identity=33.7243401759531, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI266458393, Length=272, Percent_Identity=36.7647058823529, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI266458397, Length=253, Percent_Identity=37.9446640316205, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI300863128, Length=351, Percent_Identity=28.4900284900285, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI300863124, Length=341, Percent_Identity=28.7390029325513, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI300863126, Length=160, Percent_Identity=36.875, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI266458395, Length=138, Percent_Identity=44.2028985507246, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI42822893, Length=138, Percent_Identity=44.2028985507246, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI87082093, Length=363, Percent_Identity=32.7823691460055, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1788717, Length=380, Percent_Identity=29.2105263157895, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786222, Length=346, Percent_Identity=27.7456647398844, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115535051, Length=335, Percent_Identity=28.0597014925373, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI32564160, Length=331, Percent_Identity=27.190332326284, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24648431, Length=339, Percent_Identity=32.1533923303835, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24585488, Length=345, Percent_Identity=33.6231884057971, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 38718; Mature: 38586

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSGATLAAPAAPAANAAAAPPLAGVRVVDLTELLPGPFLTQTLLEMGAEVVKIERPPH
CCCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHCCCCEEEEECCCC
GDNARRLAPGLFAALNRGKHSLYCDLKSDSGLAEVRAQIAQADILIESYRPGAMRRLGLD
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
YESLREQFPRLIYLSLTGFGQDGPHALLPGHDINYLAAAGALSLTGTPGGPPVHQAMLPI
HHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHH
ADLAGASMALSALLAALYQRTGSGRGQYLDAALADSVLHWMAPRLGLFRQKAATTADAQR
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLGGKPAYGVFRCRDGRYLTIAALEEHFWRGLNDVLGLFAANDACCVDHAARTANAETI
HHHCCCCCCCEEEECCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCHHH
NARLAERVAEYDADTLMARLANADLPVFPVLDAVEAVAQARHRSGARITETEDGPLPGFP
HHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
VTLEGMA
EEECCCC
>Mature Secondary Structure 
STSGATLAAPAAPAANAAAAPPLAGVRVVDLTELLPGPFLTQTLLEMGAEVVKIERPPH
CCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHCCCCEEEEECCCC
GDNARRLAPGLFAALNRGKHSLYCDLKSDSGLAEVRAQIAQADILIESYRPGAMRRLGLD
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
YESLREQFPRLIYLSLTGFGQDGPHALLPGHDINYLAAAGALSLTGTPGGPPVHQAMLPI
HHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHH
ADLAGASMALSALLAALYQRTGSGRGQYLDAALADSVLHWMAPRLGLFRQKAATTADAQR
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLGGKPAYGVFRCRDGRYLTIAALEEHFWRGLNDVLGLFAANDACCVDHAARTANAETI
HHHCCCCCCCEEEECCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCHHH
NARLAERVAEYDADTLMARLANADLPVFPVLDAVEAVAQARHRSGARITETEDGPLPGFP
HHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
VTLEGMA
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]