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The map label for this gene is paaJ [C]

Identifier: 94311468

GI number: 94311468

Start: 2754413

End: 2755600

Strand: Direct

Name: paaJ [C]

Synonym: Rmet_2532

Alternate gene names: 94311468

Gene position: 2754413-2755600 (Clockwise)

Preceding gene: 94311467

Following gene: 94311469

Centisome position: 70.12

GC content: 65.82

Gene sequence:

>1188_bases
ATGAGTGAAAAAGTACTGGTTGGCGGCGTGGGGATGATTCCCTTCAGCAAGCCGGGCGCCAGCCCCAGCTATACCGACAT
GGGTGCGGAGGCAGTCCGGCGGGCGCTGGCCGACGCCGGCATCGGCTACGAGCAGGTGCAGCAGGCCTACGTCGGCTATG
TGTACGGTGACTCCACCTGCGGCCAGACGGCGTTGTACGAAGTCGGCCTGACCGGCATTCCTGTGGTCAACGTCAACAAC
AACTGTTCGACGGGTTCCACCGCGCTCTACCTGGCCCGCCAGGCCGTGGCGCTGGGCGACGCCGACTGTGTGCTGGCACT
CGGCTTCGAGCAGATGCAGGCCGGCGCGCTGAAGTCGCACTGGGACGACCGCCCCAAAACACGCGCCCGCTTTGCGCACG
TGCTGCAGGATCTGACCGCCGACGTGGCTGACCTGCCGCAGGCACTGCGCACGTTCGGCGGCGCGGGCCGCGAGCATATG
CAGAAGTACGGCACGAAGATGGAAACCTTTGCCGCCATCCGCGCCAAGGCCAGCCGCCACGCCGCCAACAACCCGCTGGC
ACTGTTCCGGAACGTGGTCACCACCGAAGAGGTCATGAACGACAAGGTGATGTGGCCCGGCGTCATGACTCGCCTGATGG
CCTGCCCGCCGACCTGCGGCGCCGCCGCCGCGCTGATCGTCTCGGAGAAGTTCGCGAAGAAGCACGGTCTACGCACCGAC
GTGCAAATCCTGGCCCAGGCCATGGCCACGGATCCAGTCGAATCGTTCGATCCGCCCTCCATGATCAGCTATGCCGGCTT
CCACATGGCGCAAGCCGCTGCCAACAAGGTCTACGAGAAAGCAGGCGTGAACCCGAAGGACATCCGAGTCGCGGAGTTGC
ATGACTGCTTCGCCCATAACGAGTTGCTGAGCTACGAGGCGCTGGGCCTGTGCGGCATTGGCGAAGGCGAGAAGTTCGTG
ATGGACGGCGACAACACCTACGGCGGCCGCGTTGTGACCAATTCCTCCGGTGGCCTGCTGTCGAAGGGCCACCCGCTCGG
CGCGACGGGCCTCGCCCAGTGCTACGAACTGACCCACCAGTTGCGCGGCACCGCGGACAAGCGCCAGGTGGAAGGCGCGA
AGCTCGCGCTGCAGCACAACATCGGCCTGGGCGGCGCCTGCGTGGTGACGCTCTACGGCAAGGCCTGA

Upstream 100 bases:

>100_bases
GTGATGCGCGAACTGATCGCACGCAAGCTCTGAGCGCGACGCGAACGATCACGGTGCTACCTGCCCGCAAGCCGCGGGCC
AATTATCTGGAGAAGACAAG

Downstream 100 bases:

>100_bases
CCAACGGTCACGAATGCGGCGGCTTCGTGTCGCCGCCCCTCGAAATCTTGAAATCCCACAGCGGGAAACATCCAGCAGGA
GTATGAACATGAGCAGGAAA

Product: lipid-transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSEKVLVGGVGMIPFSKPGASPSYTDMGAEAVRRALADAGIGYEQVQQAYVGYVYGDSTCGQTALYEVGLTGIPVVNVNN
NCSTGSTALYLARQAVALGDADCVLALGFEQMQAGALKSHWDDRPKTRARFAHVLQDLTADVADLPQALRTFGGAGREHM
QKYGTKMETFAAIRAKASRHAANNPLALFRNVVTTEEVMNDKVMWPGVMTRLMACPPTCGAAAALIVSEKFAKKHGLRTD
VQILAQAMATDPVESFDPPSMISYAGFHMAQAAANKVYEKAGVNPKDIRVAELHDCFAHNELLSYEALGLCGIGEGEKFV
MDGDNTYGGRVVTNSSGGLLSKGHPLGATGLAQCYELTHQLRGTADKRQVEGAKLALQHNIGLGGACVVTLYGKA

Sequences:

>Translated_395_residues
MSEKVLVGGVGMIPFSKPGASPSYTDMGAEAVRRALADAGIGYEQVQQAYVGYVYGDSTCGQTALYEVGLTGIPVVNVNN
NCSTGSTALYLARQAVALGDADCVLALGFEQMQAGALKSHWDDRPKTRARFAHVLQDLTADVADLPQALRTFGGAGREHM
QKYGTKMETFAAIRAKASRHAANNPLALFRNVVTTEEVMNDKVMWPGVMTRLMACPPTCGAAAALIVSEKFAKKHGLRTD
VQILAQAMATDPVESFDPPSMISYAGFHMAQAAANKVYEKAGVNPKDIRVAELHDCFAHNELLSYEALGLCGIGEGEKFV
MDGDNTYGGRVVTNSSGGLLSKGHPLGATGLAQCYELTHQLRGTADKRQVEGAKLALQHNIGLGGACVVTLYGKA
>Mature_394_residues
SEKVLVGGVGMIPFSKPGASPSYTDMGAEAVRRALADAGIGYEQVQQAYVGYVYGDSTCGQTALYEVGLTGIPVVNVNNN
CSTGSTALYLARQAVALGDADCVLALGFEQMQAGALKSHWDDRPKTRARFAHVLQDLTADVADLPQALRTFGGAGREHMQ
KYGTKMETFAAIRAKASRHAANNPLALFRNVVTTEEVMNDKVMWPGVMTRLMACPPTCGAAAALIVSEKFAKKHGLRTDV
QILAQAMATDPVESFDPPSMISYAGFHMAQAAANKVYEKAGVNPKDIRVAELHDCFAHNELLSYEALGLCGIGEGEKFVM
DGDNTYGGRVVTNSSGGLLSKGHPLGATGLAQCYELTHQLRGTADKRQVEGAKLALQHNIGLGGACVVTLYGKA

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=396, Percent_Identity=56.5656565656566, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI302344760, Length=396, Percent_Identity=53.030303030303, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI302344767, Length=327, Percent_Identity=56.2691131498471, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI302344762, Length=395, Percent_Identity=49.3670886075949, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI55956775, Length=354, Percent_Identity=44.9152542372881, Blast_Score=258, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17537653, Length=397, Percent_Identity=46.5994962216625, Blast_Score=329, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24585051, Length=392, Percent_Identity=55.3571428571429, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI19921506, Length=392, Percent_Identity=54.3367346938776, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 41892; Mature: 41761

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVLVGGVGMIPFSKPGASPSYTDMGAEAVRRALADAGIGYEQVQQAYVGYVYGDSTC
CCCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCC
GQTALYEVGLTGIPVVNVNNNCSTGSTALYLARQAVALGDADCVLALGFEQMQAGALKSH
CCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
WDDRPKTRARFAHVLQDLTADVADLPQALRTFGGAGREHMQKYGTKMETFAAIRAKASRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AANNPLALFRNVVTTEEVMNDKVMWPGVMTRLMACPPTCGAAAALIVSEKFAKKHGLRTD
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
VQILAQAMATDPVESFDPPSMISYAGFHMAQAAANKVYEKAGVNPKDIRVAELHDCFAHN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHH
ELLSYEALGLCGIGEGEKFVMDGDNTYGGRVVTNSSGGLLSKGHPLGATGLAQCYELTHQ
HHHHHHHHCEEECCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
LRGTADKRQVEGAKLALQHNIGLGGACVVTLYGKA
HHCCCHHHHCCCHHEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
SEKVLVGGVGMIPFSKPGASPSYTDMGAEAVRRALADAGIGYEQVQQAYVGYVYGDSTC
CCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCC
GQTALYEVGLTGIPVVNVNNNCSTGSTALYLARQAVALGDADCVLALGFEQMQAGALKSH
CCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
WDDRPKTRARFAHVLQDLTADVADLPQALRTFGGAGREHMQKYGTKMETFAAIRAKASRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AANNPLALFRNVVTTEEVMNDKVMWPGVMTRLMACPPTCGAAAALIVSEKFAKKHGLRTD
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
VQILAQAMATDPVESFDPPSMISYAGFHMAQAAANKVYEKAGVNPKDIRVAELHDCFAHN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHH
ELLSYEALGLCGIGEGEKFVMDGDNTYGGRVVTNSSGGLLSKGHPLGATGLAQCYELTHQ
HHHHHHHHCEEECCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
LRGTADKRQVEGAKLALQHNIGLGGACVVTLYGKA
HHCCCHHHHCCCHHEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]