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The map label for this gene is glmM

Identifier: 94311124

GI number: 94311124

Start: 2393789

End: 2395132

Strand: Reverse

Name: glmM

Synonym: Rmet_2186

Alternate gene names: 94311124

Gene position: 2395132-2393789 (Counterclockwise)

Preceding gene: 94311125

Following gene: 94311123

Centisome position: 60.97

GC content: 63.84

Gene sequence:

>1344_bases
ATGACACGCAAGTATTTCGGGACAGACGGCGTGCGGGGTCGGGTCGGCGACGCGCCGATCACGCCGGATTTTGTGATGCG
ACTTGGCCATGCGGCCGGCAAGGTGCTGGCGCTGGGGCAGAAGACTTCGCAGGGCAAGCCCACCGTCCTGATCGGCAAGG
ATACGCGGATCTCGGGCTATATGCTGGAAGCGGCACTTGAGGCCGGCTTTACAGCGGCGGGCGTCAATGTGCTGCTGACT
GGCCCGTTGCCCACGCCGGGCATTGCCTATCTCACGCGAACGCTCCGGTTGGCGGCGGGCGTGGTGATTTCCGCAAGCCA
CAACCCGTACTACGACAACGGTATCAAGTTCTTTTCGGCATCGGGTGACAAGCTGCCCGATGACGTGGAATCGCAGATCG
AGGCGATGGTCGAAGAGCCGATGACCTGCGTGCACTCGGATGAACTCGGCCGCGCCCGCCGGATCGACGACGCTGCGGGT
CGCTACATCGAGTTCTGCAAGAGCACGTTCCCGTATGAGCATGACCTGCATGGTCTGAAGATCGTAGTCGATTGCGCTAA
TGGTGCCGCTTATCACATTGCCCCGCATGTGTTCCACGAGTTGGGCGCCGAGGTGATCTCGATCGGCAACCAGCCCAATG
GCCGCAACATCAACGCCGGATATGGTGCCACCGCCCCCGAGAAGCTGATCGAAGCAGTGAAGGCTAACGGCGCGGATCTT
GGCCTGGCATTCGACGGCGATGCCGACCGCCTGCAGGTGGTGGACGCCGATGGCCGGTTGTACAACGGCGATGAGTTGCT
CTATCTGATCGTGCGCGATCGTCAGGCGTCTGGCCAGCGGGTAGAAGGCGCGGTCGGCACGCTGATGACGAACATGGCGG
TCGAACTGGCGCTCAAGCGCCTTGGCGTGTCGTTCGTGCGCGCCAAGGTTGGCGACCGTTACGTGCTCGAGGAACTCAAT
CGGCACCACTGGCAACTCGGTGGCGAGGGCTCCGGGCATCTGCTGTGCCTGGACCGGCATACCACGGGCGATGGCATCGT
GTCCGCGCTGCAGGTGCTGGCCGCGCTACGCCGCAGTGGCAAGACTCTGCCGCAACTGCTGGATGGCGTGAGCCTGTTCC
CGCAGACGCTTATCAATGTGCGCGTCGAGAAGGGTTTTGACTGGCAGAACCACGCTGGACTCAAGGCTGTCCGGGACCGC
GTGGAGCCCGAGCTGGAAGGACGGGGACGGGTGCTGATCCGCGCCTCGGGAACGGAGCCCGTGGTCCGTGTGATGGTGGA
GGCCGAGCAGGTGGAAACCGCTGAGCGTGCCGCGCAGGAGCTTGCCGCCGCATTGCGCGCCTGA

Upstream 100 bases:

>100_bases
GGGTACATGATGTTGAACAAACAGTGGACGCCCTCAAGGTGTGGTGGGCCGTCCGCCAAGAATCAGTTGCCCCCGATGGG
CAACACGGAGAATGAGAAAC

Downstream 100 bases:

>100_bases
GCGTTCTTCTGGGCAGCCCAACGCTGTCGGAAGGCCACGGCACTGTGTCGTGGCCTTTTCTTTTTCGCAAATAAAGCAAT
TAACCGCCATCATCCGCCAC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTRKYFGTDGVRGRVGDAPITPDFVMRLGHAAGKVLALGQKTSQGKPTVLIGKDTRISGYMLEAALEAGFTAAGVNVLLT
GPLPTPGIAYLTRTLRLAAGVVISASHNPYYDNGIKFFSASGDKLPDDVESQIEAMVEEPMTCVHSDELGRARRIDDAAG
RYIEFCKSTFPYEHDLHGLKIVVDCANGAAYHIAPHVFHELGAEVISIGNQPNGRNINAGYGATAPEKLIEAVKANGADL
GLAFDGDADRLQVVDADGRLYNGDELLYLIVRDRQASGQRVEGAVGTLMTNMAVELALKRLGVSFVRAKVGDRYVLEELN
RHHWQLGGEGSGHLLCLDRHTTGDGIVSALQVLAALRRSGKTLPQLLDGVSLFPQTLINVRVEKGFDWQNHAGLKAVRDR
VEPELEGRGRVLIRASGTEPVVRVMVEAEQVETAERAAQELAAALRA

Sequences:

>Translated_447_residues
MTRKYFGTDGVRGRVGDAPITPDFVMRLGHAAGKVLALGQKTSQGKPTVLIGKDTRISGYMLEAALEAGFTAAGVNVLLT
GPLPTPGIAYLTRTLRLAAGVVISASHNPYYDNGIKFFSASGDKLPDDVESQIEAMVEEPMTCVHSDELGRARRIDDAAG
RYIEFCKSTFPYEHDLHGLKIVVDCANGAAYHIAPHVFHELGAEVISIGNQPNGRNINAGYGATAPEKLIEAVKANGADL
GLAFDGDADRLQVVDADGRLYNGDELLYLIVRDRQASGQRVEGAVGTLMTNMAVELALKRLGVSFVRAKVGDRYVLEELN
RHHWQLGGEGSGHLLCLDRHTTGDGIVSALQVLAALRRSGKTLPQLLDGVSLFPQTLINVRVEKGFDWQNHAGLKAVRDR
VEPELEGRGRVLIRASGTEPVVRVMVEAEQVETAERAAQELAAALRA
>Mature_446_residues
TRKYFGTDGVRGRVGDAPITPDFVMRLGHAAGKVLALGQKTSQGKPTVLIGKDTRISGYMLEAALEAGFTAAGVNVLLTG
PLPTPGIAYLTRTLRLAAGVVISASHNPYYDNGIKFFSASGDKLPDDVESQIEAMVEEPMTCVHSDELGRARRIDDAAGR
YIEFCKSTFPYEHDLHGLKIVVDCANGAAYHIAPHVFHELGAEVISIGNQPNGRNINAGYGATAPEKLIEAVKANGADLG
LAFDGDADRLQVVDADGRLYNGDELLYLIVRDRQASGQRVEGAVGTLMTNMAVELALKRLGVSFVRAKVGDRYVLEELNR
HHWQLGGEGSGHLLCLDRHTTGDGIVSALQVLAALRRSGKTLPQLLDGVSLFPQTLINVRVEKGFDWQNHAGLKAVRDRV
EPELEGRGRVLIRASGTEPVVRVMVEAEQVETAERAAQELAAALRA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=60.6263982102908, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1788361, Length=453, Percent_Identity=29.3598233995585, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_RALME (Q1LLB1)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_584334.1
- ProteinModelPortal:   Q1LLB1
- SMR:   Q1LLB1
- STRING:   Q1LLB1
- GeneID:   4039003
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2186
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   CRVYIRP
- PhylomeDB:   Q1LLB1
- ProtClustDB:   PRK10887
- BioCyc:   RMET266264:RMET_2186-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48131; Mature: 48000

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKYFGTDGVRGRVGDAPITPDFVMRLGHAAGKVLALGQKTSQGKPTVLIGKDTRISGY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCHH
MLEAALEAGFTAAGVNVLLTGPLPTPGIAYLTRTLRLAAGVVISASHNPYYDNGIKFFSA
HHHHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEC
SGDKLPDDVESQIEAMVEEPMTCVHSDELGRARRIDDAAGRYIEFCKSTFPYEHDLHGLK
CCCCCCHHHHHHHHHHHHCCHHHHCCHHCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCEE
IVVDCANGAAYHIAPHVFHELGAEVISIGNQPNGRNINAGYGATAPEKLIEAVKANGADL
EEEECCCCCEEEHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
GLAFDGDADRLQVVDADGRLYNGDELLYLIVRDRQASGQRVEGAVGTLMTNMAVELALKR
EEEECCCCCEEEEEECCCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGVSFVRAKVGDRYVLEELNRHHWQLGGEGSGHLLCLDRHTTGDGIVSALQVLAALRRSG
HHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KTLPQLLDGVSLFPQTLINVRVEKGFDWQNHAGLKAVRDRVEPELEGRGRVLIRASGTEP
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCC
VVRVMVEAEQVETAERAAQELAAALRA
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRKYFGTDGVRGRVGDAPITPDFVMRLGHAAGKVLALGQKTSQGKPTVLIGKDTRISGY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCHH
MLEAALEAGFTAAGVNVLLTGPLPTPGIAYLTRTLRLAAGVVISASHNPYYDNGIKFFSA
HHHHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEC
SGDKLPDDVESQIEAMVEEPMTCVHSDELGRARRIDDAAGRYIEFCKSTFPYEHDLHGLK
CCCCCCHHHHHHHHHHHHCCHHHHCCHHCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCEE
IVVDCANGAAYHIAPHVFHELGAEVISIGNQPNGRNINAGYGATAPEKLIEAVKANGADL
EEEECCCCCEEEHHHHHHHHHCHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
GLAFDGDADRLQVVDADGRLYNGDELLYLIVRDRQASGQRVEGAVGTLMTNMAVELALKR
EEEECCCCCEEEEEECCCCEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGVSFVRAKVGDRYVLEELNRHHWQLGGEGSGHLLCLDRHTTGDGIVSALQVLAALRRSG
HHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KTLPQLLDGVSLFPQTLINVRVEKGFDWQNHAGLKAVRDRVEPELEGRGRVLIRASGTEP
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCC
VVRVMVEAEQVETAERAAQELAAALRA
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA